The Oncosearch | Oncotarget

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

Stefanie Schlager, Carina Salomon, Sabine Olt, Christoph Albrecht, Anja Ebert, Oliver Bergner, Johannes Wachter, Francesca Trapani, Daniel Gerlach, Tilman Voss, Anna Traunbauer, Julian Jude, Matthias Hinterndorfer, Martina Minnich, Norbert Schweifer, Sophia M. Blake, Vittoria Zinzalla, Barbara Drobits, Darryl B. McConnell, Norbert Kraut, Mark Pearson, Johannes Zuber, Manfred Koegl

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 875-890

Keywords: BCL6, DLBCL, lymphoma, inducible CRISPR/Cas9, in vivo xenograft

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020 · Vol. 11, No. 18 · pp. 1576-1589

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment Research Paper

Shrilekha Misra, Xiaoli Zhang, Nissar Ahmad Wani, Steven Sizemore, Alo Ray

Published Feb 25, 2020 · Vol. 11, No. 8 · pp. 784-800

Keywords: triple-negative breast cancer, MLN4924, cisplatin, cell cycle, DNA damage

SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism Research Paper

Valeria Santoro, Ilya Kovalenko, Kim Vriens, Stefan Christen, Andreas Bernthaler, Andrea Haegebarth, Sarah-Maria Fendt, Sven Christian

Published Feb 25, 2020 · Vol. 11, No. 8 · pp. 801-812

Keywords: transporter, mitochondria, metabolism, ROS, FAD

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Pierre Boyé, Franck Floch, François Serres, Zacharie Segaoula, Juliette Hordeaux, Quentin Pascal, Virginie Coste, Sandy Courapied, Emmanuel Bouchaert, Agata Rybicka, Claire Mazuy, Laurent Marescaux, Kévyn Geeraert, Corinne Fournel-Fleury, Alain Duhamel, François Machuron, Pierre Ferré, Aurélie Pétain, Nicolas Guilbaud, Dominique Tierny, Bruno Gomes

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 671-686

Keywords: etoposide phosphate, F14512, non-Hodgkin lymphoma, pet dog model, P-glycoprotein

Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells Research Paper

Francesca Punzo, Giulia Bellini, Chiara Tortora, Daniela Di Pinto, Maura Argenziano, Elvira Pota, Alessandra Di Paola, Martina Di Martino, Francesca Rossi

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 687-698

Keywords: macrophage polarization, tumor micro-environment, osteosarcoma, Mifamurtide, MG63

DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR Research Paper

Sonia Zicari, Adhikarimayum Lakhikumar Sharma, Geetaram Sahu, Larisa Dubrovsky, Lin Sun, Han Yue, Tejaswi Jada, Alex Ochem, Gary Simon, Michael Bukrinsky, Mudit Tyagi

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 699-726

Keywords: HIV, DNA-PK, transcription, replication, DNA-PK inhibitors

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Manish Charan, Piyush Dravid, Maren Cam, Bhuvana Setty, Ryan D. Roberts, Peter J. Houghton, Hakan Cam

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 510-522

Keywords: pre-metastatic niche formation, osteosarcoma, ANGPTL2, tumor microenvironment, neutrophils

Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib Research Paper

Raquel Carvalho Montenegro, Alison Howarth, Alessandro Ceroni, Vita Fedele, Batoul Farran, Felipe Pantoja Mesquita, Martin Frejno, Benedict-Tilman Berger, Stephanie Heinzlmeir, Heba Z. Sailem, Roberta Tesch, Daniel Ebner, Stefan Knapp, Rommel Burbano, Bernhard Kuster, Susanne Müller

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 535-549

Keywords: gastric cancer, dasatinib, biomarker, SRC-kinases, SIK2

Correction: miR146a-mediated targeting of FANCM during inflammation compromises genome integrity Correction

Devakumar Sundaravinayagam, Hye Rim Kim, TingTing Wu, Hyun Hee Kim, Hyun-Seo Lee, Semo Jun, Jeong-Heon Cha, Younghoon Kee, Ho Jin You, Jung-Hee Lee

Published Jan 30, 2020 · Vol. 11, No. 21 · pp. 2024-2025

Correction: Metabolomic analysis of uterine serous carcinoma with acquired resistance to paclitaxel Correction

Manabu Seino, Tsuyoshi Ohta, Akiko Sugiyama, Hirotsugu Sakaki, Takeshi Sudo, Seiji Tsutsumi, Shogo Shigeta, Hideki Tokunaga, Masafumi Toyoshima, Nobuo Yaegashi, Satoru Nagase

Published Jan 28, 2020 · Vol. 12, No. 23 · pp. 2321-2322

Correction: A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice Correction

Prakash Gangadaran, Xiu Juan Li, Ho Won Lee, Ji Min Oh, Senthilkumar Kalimuthu, Ramya Lakshmi Rajendran, Seung Hyun Son, Se Hwan Baek, Thoudam Debraj Singh, Liya Zhu, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee, Byeong-Cheol Ahn

Published Jan 28, 2020 · Vol. 11, No. 11 · pp. 1004-1005

Sexual dimorphism in atrophic effects of topical glucocorticoids is driven by differential regulation of atrophogene REDD1 in male and female skin Research Paper

Gleb Baida, Shivani Agarwal, Ben Readhead, Joel T. Dudley, Irina Budunova

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 409-418

Keywords: glucocorticoid, skin atrophy, REDD1, mTOR, sexual dimorphism

Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery Research Paper

Ling F. Ye, Eduard Reznik, Joshua M. Korn, Fallon Lin, Guizhi Yang, Kimberly Malesky, Hui Gao, Alice Loo, Raymond Pagliarini, Tom Mikkelsen, Donald C. Lo, Ana C. deCarvalho, Brent R. Stockwell

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 443-451

Keywords: cell death, chemical biology, glioma, cancer

Correction: JARID1B promotes metastasis and epithelial-mesenchymal transition via PTEN/AKT signaling in hepatocellular carcinoma cells Correction

Bo Tang, Guangying Qi, Fang Tang, Shengguang Yuan, Zhenran Wang, Xingsi Liang, Bo Li, Shuiping Yu, Jie Liu, Qi Huang, Yangchao Wei, Run Zhai, Biao Lei, Hongping Yu, Xingyuan Jiao, Songqing He

Published Jan 26, 2020 · Vol. 11, No. 19 · pp. 1797-1798

Correction: Oroxylin A modulates mitochondrial function and apoptosis in human colon cancer cells by inducing mitochondrial translocation of wild-type p53 Correction

Chen Qiao, Na Lu, Yuxin Zhou, Ting Ni, Yuanyuan Dai, Zhiyu Li, Qinglong Guo, Libin Wei

Published Jan 22, 2020

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Hengyu Lu, Chen Liu, Hung Huynh, Thi Bich Uyen Le, Matthew J. LaMarche, Morvarid Mohseni, Jeffrey A. Engelman, Peter S. Hammerman, Giordano Caponigro, Huai-Xiang Hao

Published Jan 21, 2020 · Vol. 11, No. 3 · pp. 265-281

Keywords: SHP2, FGFR, resistance, feedback activation

Correction: P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis Correction

Jun Zhang, Ke Ma, Tingting Qi, Xiaoning Wei, Qing Zhang, Guanwu Li, Jen-Fu Chiu

Published Jan 16, 2020 · Vol. 12, No. 23 · pp. 2320-2320

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Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment Research Paper

SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism Research Paper

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells Research Paper

DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR Research Paper

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib Research Paper

Correction: miR146a-mediated targeting of FANCM during inflammation compromises genome integrity Correction

Correction: Metabolomic analysis of uterine serous carcinoma with acquired resistance to paclitaxel Correction

Correction: A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice Correction

Sexual dimorphism in atrophic effects of topical glucocorticoids is driven by differential regulation of atrophogene REDD1 in male and female skin Research Paper

Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery Research Paper

Correction: JARID1B promotes metastasis and epithelial-mesenchymal transition via PTEN/AKT signaling in hepatocellular carcinoma cells Correction

Correction: Oroxylin A modulates mitochondrial function and apoptosis in human colon cancer cells by inducing mitochondrial translocation of wild-type p53 Correction

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Correction: P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis Correction

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment Research Paper

SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism Research Paper

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells Research Paper

DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR Research Paper

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib Research Paper

Correction: miR146a-mediated targeting of FANCM during inflammation compromises genome integrity Correction

Correction: Metabolomic analysis of uterine serous carcinoma with acquired resistance to paclitaxel Correction

Correction: A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice Correction

Sexual dimorphism in atrophic effects of topical glucocorticoids is driven by differential regulation of atrophogene REDD1 in male and female skin Research Paper

Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery Research Paper

Correction: JARID1B promotes metastasis and epithelial-mesenchymal transition via PTEN/AKT signaling in hepatocellular carcinoma cells Correction

Correction: Oroxylin A modulates mitochondrial function and apoptosis in human colon cancer cells by inducing mitochondrial translocation of wild-type p53 Correction

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Correction: P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis Correction