The Oncosearch | Oncotarget

Tumor necrosis factor related apoptosis inducing ligand (TRAIL) regulates deubiquitinase USP5 in tumor cells Research Paper

Harish Potu, Malathi Kandarpa, Luke F. Peterson, Nicholas J. Donato, Moshe Talpaz

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5745-5754

Keywords: USP5, ubiquitin, TRAIL, DUB inhibitor, G9

GSTΠ stimulates caveolin-1-regulated polyamine uptake via actin remodeling Research Paper

Takeshi Uemura, George Tsaprailis, Eugene W. Gerner

Published Oct 1, 2019 · Vol. 10, No. 55 · pp. 5713-5723

Keywords: polyamine, caveolin, GSTπ, transport, actin

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy Research Paper

Caitlin D. Lowery, Wayne Blosser, Michele Dowless, Matthew Renschler, Lisa V. Perez, Jennifer Stephens, Bronislaw Pytowski, Heather Wasserstrom, Louis F. Stancato, Beverly Falcon

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5523-5533

Keywords: angiogenesis, pediatric cancer, VEGFR2, ramucirumab, DC101

SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells Research Paper

Ming-Bo Huang, Jennifer Y. Wu, James Lillard, Vincent C. Bond

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5419-5438

Keywords: extracellular vesicles, mortalin, complement, SMR peptides, breast cancer

Preliminary observations on soluble programmed cell death protein-1 as a prognostic and predictive biomarker in patients with metastatic melanoma treated with patient-specific autologous vaccines Research Paper

Robert O. Dillman, Gabriel I. Nistor, Bryce T. McLelland, Candace Hsieh, Aleksandra J. Poole, Andrew N. Cornforth, Hans S. Keirstead

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5359-5371

Keywords: programmed cell death protein -1 (PD-1), dendritic cell vaccines, metastatic melanoma

Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells Research Paper

Piyush More, Ute Goedtel-Armbrust, Viral Shah, Marianne Mathaes, Thomas Kindler, Miguel A. Andrade-Navarro, Leszek Wojnowski

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5298-5312

Keywords: topoisomerase II poisons, DNA damage, gene expression, combination therapy, cancer essentiality

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells Research Paper

El-Habib Dakir, Faustino Mollinedo

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5313-5331

Keywords: miRNA, miR-125a-5p, miR-17-92, neutrophil differentiation, human

Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer Research Paper

Maud-Emmanuelle Gilles, Liangliang Hao, Kaelyn Brown, Jihoon Lim, Sangeeta N. Bhatia, Frank J. Slack

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5349-5358

Keywords: miRNAs, KRAS, RNA-based-therapy, PDAC, tumor-penetrating nanocomplexes

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Takeshi Jimbo, Mana Hatanaka, Takahiro Komatsu, Tomoe Taira, Kentaro Kumazawa, Naoyuki Maeda, Takashi Suzuki, Masahiro Ota, Noriyasu Haginoya, Takeshi Isoyama, Kosaku Fujiwara

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5152-5167

Keywords: AXL, DS-1205, EGFR-TKI resistance, erlotinib, osimertinib

TAK228 enhances antitumor activity of eribulin in triple negative breast cancer Research Paper

Nicci Owusu-Brackett, Kurt W. Evans, Argun Akcakanat, Erkan Yuca, Coya Tapia, Yasmeen Qamar Rizvi, Ecaterina Ileana Dumbrava, Filip Janku, Funda Meric-Bernstam

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5011-5019

Keywords: breast cancer, TAK228, PI3K, PTEN, TNBC

Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins Research Paper

Manabu Sasada, Takuya Iyoda, Tatsufumi Asayama, Yusuke Suenaga, Shunsuke Sakai, Naoya Kase, Hiroaki Kodama, Sana Yokoi, Yoichiro Isohama, Fumio Fukai

Published Aug 13, 2019 · Vol. 10, No. 48 · pp. 4960-4972

Keywords: integrin, Myc, proteasomal degradation, fibronectin, neuroblastoma

ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations Research Paper

Simon Durand, Cécile Pierre-Eugène, Olivier Mirabeau, Caroline Louis-Brennetot, Valérie Combaret, Léo Colmet-Daage, Orphée Blanchard, Angela Bellini, Estelle Daudigeos-Dubus, Virginie Raynal, Gudrun Schleiermacher, Sylvain Baulande, Olivier Delattre, Isabelle Janoueix-Lerosey

Published Aug 13, 2019 · Vol. 10, No. 48 · pp. 4937-4950

Keywords: neuroblastoma, ALK mutations, heterogeneity, clonal evolution, ALK inhibitors

Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth Research Paper

Letícia Scussel Bergamin, Marina Capece, Erica Salaro, Alba Clara Sarti, Simonetta Falzoni, Mery Stéfani Leivas Pereira, Marco Antônio De Bastiani, Juliete Nathali Scholl, Ana Maria O. Battastini, Francesco Di Virgilio

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4840-4856

Keywords: cancer, glioma, P2X7R, purinergic signaling, extracellular ATP

AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma Research Paper

Huda H. Al-Khalaf, Abdelilah Aboussekhra

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4868-4879

Keywords: osteosarcoma, AUF1, VEGF-A, HIF-1α, angiogenesis

The p21 levels have the potential to be a monitoring marker for ribociclib in breast cancer Research Paper

Masafumi Iida, Misato Nakamura, Emi Tokuda, Daichi Toyosawa, Toshifumi Niwa, Noriaki Ohuchi, Takanori Ishida, Shin-ichi Hayashi

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4907-4918

Keywords: breast cancer, CDK4/6 inhibitor, resistance, CDK6, p21

Dominant role of the α-chain in rejection of tumor cells bearing a specific alloantigen in TCRα transgenic mice and in in vitro experiments Research Paper

Maria Zamkova, Anastasiya Kalinina, Yuliya Silaeva, Nadezhda Persiyantseva, Alexandra Bruter, Alexey Deikin, Ludmila Khromykh, Dmitry Kazansky

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4808-4821

Keywords: transgenic mice, TCRα, tumor, alloantigen

Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome Research Paper

Tengpeng Hu, Terkild Brink Buus, Thorbjørn Krejsgaard, Anneline Nansen, Betina Kerstin Lundholt, Pieter Spee, Simon Fredholm, David Leander Petersen, Edda Blümel, Maria Gluud, Madalena N. Monteiro, Andreas Willerslev-Olsen, Mads Hald Andersen, Per thor Straten, Özcan Met, Veronica Stolearenco, Hanne Fogh, Robert Gniadecki, Claudia Nastasi, Thomas Litman, Anders Woetmann, Lise Mette Rahbek Gjerdrum, Niels Ødum

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4894-4906

Keywords: Sézary syndrome, Kv1.3 channel, ShK, cutaneous T-cell lymphoma, cancer

Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response Research Paper

Alessia Garufi, Gianandrea Traversi, Maria Saveria Gilardini Montani, Valerio D’Orazi, Giuseppa Pistritto, Mara Cirone, Gabriella D’Orazi

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4691-4702

Keywords: chemoresistance, reactive oxygen species (ROS), high glucose (HG), cancer, nuclear factor erythroid 2-related factor 2 (NRF2)

Transglutaminase 2 maintains a colorectal cancer stem phenotype by regulating epithelial-mesenchymal transition Research Paper

Oluseyi Ayinde, Zhuo Wang, Giulia Pinton, Laura Moro, Martin Griffin

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4556-4569

Keywords: transglutaminase 2, colorectal cancer, epithelial-mesenchymal transition, cancer Stem Cells, β-catenin

Correction: Vanillic acid attenuates testosterone-induced benign prostatic hyperplasia in rats and inhibits proliferation of prostatic epithelial cells Correction

Yunu Jung, Jinbong Park, Hye-Lin Kim, Dong-Hyun Youn, JongWook Kang, Seona Lim, Mi-Young Jeong, Gautam Sethi, Sung-Joo Park, Kwang Seok Ahn, Jae-Young Um

Published Jul 15, 2019 · Vol. 10, No. 44 · pp. 4611-4611

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Tumor necrosis factor related apoptosis inducing ligand (TRAIL) regulates deubiquitinase USP5 in tumor cells Research Paper

GSTΠ stimulates caveolin-1-regulated polyamine uptake via actin remodeling Research Paper

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy Research Paper

SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells Research Paper

Preliminary observations on soluble programmed cell death protein-1 as a prognostic and predictive biomarker in patients with metastatic melanoma treated with patient-specific autologous vaccines Research Paper

Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells Research Paper

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells Research Paper

Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer Research Paper

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

TAK228 enhances antitumor activity of eribulin in triple negative breast cancer Research Paper

Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins Research Paper

ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations Research Paper

Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth Research Paper

AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma Research Paper

The p21 levels have the potential to be a monitoring marker for ribociclib in breast cancer Research Paper

Dominant role of the α-chain in rejection of tumor cells bearing a specific alloantigen in TCRα transgenic mice and in in vitro experiments Research Paper

Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome Research Paper

Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response Research Paper

Transglutaminase 2 maintains a colorectal cancer stem phenotype by regulating epithelial-mesenchymal transition Research Paper

Correction: Vanillic acid attenuates testosterone-induced benign prostatic hyperplasia in rats and inhibits proliferation of prostatic epithelial cells Correction

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Tumor necrosis factor related apoptosis inducing ligand (TRAIL) regulates deubiquitinase USP5 in tumor cells Research Paper

GSTΠ stimulates caveolin-1-regulated polyamine uptake via actin remodeling Research Paper

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy Research Paper

SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells Research Paper

Preliminary observations on soluble programmed cell death protein-1 as a prognostic and predictive biomarker in patients with metastatic melanoma treated with patient-specific autologous vaccines Research Paper

Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells Research Paper

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells Research Paper

Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer Research Paper

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

TAK228 enhances antitumor activity of eribulin in triple negative breast cancer Research Paper

Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins Research Paper

ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations Research Paper

Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth Research Paper

AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma Research Paper

The p21 levels have the potential to be a monitoring marker for ribociclib in breast cancer Research Paper

Dominant role of the α-chain in rejection of tumor cells bearing a specific alloantigen in TCRα transgenic mice and in in vitro experiments Research Paper

Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome Research Paper

Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response Research Paper

Transglutaminase 2 maintains a colorectal cancer stem phenotype by regulating epithelial-mesenchymal transition Research Paper

Correction: Vanillic acid attenuates testosterone-induced benign prostatic hyperplasia in rats and inhibits proliferation of prostatic epithelial cells Correction