The Oncosearch | Oncotarget

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Subarna Ghosh, Priyanka Dey Talukdar, Abhinandan Bhattacharjee, Sarbani Giri, Nitai Pada Bhattacharyya, Urmi Chatterji

Published Jul 2, 2021 · Vol. 12, No. 15 · pp. 1520-1539

Keywords: arecoline, tight junction, head and neck cancer, lncRNA-NEAT1, JunD

Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer Research Paper

Tara Williamson, Michelle Carvalho de Abreu, Dimitri G. Trembath, Cory Brayton, Byunghak Kang, Thais Biude Mendes, Paulo Pimentel de Assumpção, Janete M. Cerutti, Gregory J. Riggins

Published Jun 22, 2021 · Vol. 12, No. 14 · pp. 1326-1338

Keywords: mebendazole, pancreatic cancer, cancer prevention, metastasis, mouse models

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Reza Bayat Mokhtari, Bessi Qorri, Narges Baluch, Angelo Sparaneo, Federico Pio Fabrizio, Lucia Anna Muscarella, Albina Tyker, Sushil Kumar, Hai-Ling Margaret Cheng, Myron R. Szewczuk, Bikul Das, Herman Yeger

Published Jun 22, 2021 · Vol. 12, No. 15 · pp. 1470-1489

Keywords: sulforaphane, acetazolamide, bronchial carcinoid tumors, serotonin, carbonic anhydrase

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Maura Argenziano, Chiara Tortora, Alessandra Di Paola, Elvira Pota, Martina Di Martino, Daniela Di Pinto, Caterina Di Leva, Francesca Rossi

Published Jun 16, 2021 · Vol. 12, No. 14 · pp. 1377-1387

Keywords: acute monocytic leukemia, eltrombopag, deferasirox, iron chelation, cancer

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Catherine T. Haring, Chandan Bhambhani, Collin Brummel, Brittany Jewell, Emily Bellile, Molly E. Heft Neal, Erin Sandford, Ryan M. Spengler, Apurva Bhangale, Matthew E. Spector, Jonathan McHugh, Mark E. Prince, Michelle Mierzwa, Francis P. Worden, Muneesh Tewari, Paul L. Swiecicki, J. Chad Brenner

Published Jun 11, 2021 · Vol. 12, No. 13 · pp. 1214-1229

Keywords: HPV, head and neck cancer, oropharyngeal cancer, ctDNA, circulating tumor DNA

Correction: Enhanced anti-tumor activity and cytotoxic effect on cancer stem cell population of metformin-butyrate compared with metformin HCl in breast cancer Correction

Kyung-Min Lee, Minju Lee, Jiwoo Lee, Sung Wuk Kim, Hyeong-Gon Moon, Dong-Young Noh, Wonshik Han

Published Jun 6, 2021 · Vol. 12, No. 12 · pp. 1197-1198

Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy Research Paper

Lina Alhalhooly, Babak Mamnoon, Jiha Kim, Sanku Mallik, Yongki Choi

Published May 20, 2021 · Vol. 12, No. 12 · pp. 1165-1177

Keywords: cellular stiffness, roughness, adhesion, drug resistance, hypoxia

CEA as a blood-based biomarker in anal cancer Research Paper

Robert Hester, Shailesh Advani, Asif Rashid, Emma Holliday, Craig Messick, Prajnan Das, Yi-Qian N. You, Cullen Taniguchi, Eugene J. Koay, Brian Bednarski, Miguel Rodriguez-Bigas, John Skibber, Robert Wolff, George J. Chang, Bruce D. Minsky, Wai Chin Foo, Nicole Rothschild, Van K. Morris, Cathy Eng

Published May 5, 2021 · Vol. 12, No. 11 · pp. 1037-1045

Keywords: carcinoembryonic antigen, squamous cell carcinoma of anal canal, anal cancer, biomarkers, HPV

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Radhika R. Gudi, Harinarayanan Janakiraman, Philip H. Howe, Viswanathan Palanisamy, Chenthamarakshan Vasu

Published Mar 27, 2021 · Vol. 12, No. 8 · pp. 807-822

Keywords: tumorigenesis, epithelial-mesenchymal transition, oral squamous cell carcinoma, EGFR, CPAP

Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma Research Paper

Julien Schaller, Hélène Maby-El Hajjami, Sylvie Rusakiewicz, Kalliopi Ioannidou, Nathalie Piazzon, Alexandra Miles, Déla Golshayan, Olivier Gaide, Daniel Hohl, Daniel E. Speiser, Karin Schaeuble

Published Mar 5, 2021 · Vol. 12, No. 7 · pp. 638-648

Keywords: lymphatic vessel, CD8+ T cell, perineural infiltration, skin squamous-cell carcinoma, tumor immunology

Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells Research Paper

Bhaskar Bhattacharya, Daniel Q. Huang, Sarah Hong Hui Low, Gim Hwa Tan, Min Ji Han, Sanamerjit Singh, Benny Tang, Sheng Chun Chang, Joey Sze Yun Lim, Mohd Feroz Mohd Omar, Yock Young Dan, Richie Soong

Published Mar 3, 2021 · Vol. 12, No. 7 · pp. 674-685

Keywords: drug development, microenvironment, glycolysis

The interaction between cancer associated fibroblasts and tumor associated macrophages via the osteopontin pathway in the tumor microenvironment of hepatocellular carcinoma Research Paper

Kazunori Tokuda, Yuji Morine, Katsuki Miyazaki, Shinichiro Yamada, Yu Saito, Masaaki Nishi, Takuya Tokunaga, Tetsuya Ikemoto, Satoru Imura, Mitsuo Shimada

Published Jan 27, 2021 · Vol. 12, No. 4 · pp. 333-343

Keywords: hepatocellular carcinoma, osteopontin, cancer associated fibroblast, tumor associated macrophage, tumor microenvironment

MicroRNA-214 enriched exosomes from human cerebral endothelial cells (hCEC) sensitize hepatocellular carcinoma to anti-cancer drugs Research Paper

Louie Semaan, Qingning Zeng, Yong Lu, Yi Zhang, Mehdi Mohamad Zreik, Mohamad Baqer Chamseddine, Michael Chopp, Zheng Gang Zhang, Dilip Moonka

Published Jan 25, 2021 · Vol. 12, No. 3 · pp. 185-198

Keywords: hepatocellular carcinoma (HCC), human cerebral endothelial cells-derived exosomes, microRNA-214, therapeutic efficacy, anti-cancer drug

Krüppel-like factor 4 promotes survival and expansion in acute myeloid leukemia cells Research Paper

Andrew Henry Lewis, Cory Seth Bridges, Viraaj Singh Punia, Abraham Fausto Jornada Cooper, Monica Puppi, H. Daniel Lacorazza

Published Jan 25, 2021 · Vol. 12, No. 4 · pp. 255-267

Keywords: acute myeloid leukemia, KLF4, cancer, gene editing, cell growth

Oncolytic virotherapy with SOCS3 enhances viral replicative potency and oncolysis for gastric cancer Research Paper

Shuichi Matsumura, Mikihito Nakamori, Toshiaki Tsuji, Tomoya Kato, Masaki Nakamura, Toshiyasu Ojima, Hiroshi Fukuhara, Yasushi Ino, Tomoki Todo, Hiroki Yamaue

Published Jan 22, 2021 · Vol. 12, No. 4 · pp. 344-354

Keywords: oncolytic virus, herpes simplex virus, gastric cancer

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Harish Potu, Malathi Kandarpa, Luke F. Peterson, Alison Durham, Nicholas J. Donato, Moshe Talpaz

Published Jan 12, 2021 · Vol. 12, No. 3 · pp. 160-172

Keywords: melanoma, deubiquitinase (DUB) enzyme, transcription factors, USP9X, DUB inhibitor

The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation Research Paper

Karim Abid, Maja Beck Popovic, Katia Balmas Bourloud, Jacqueline Schoumans, Joana Grand-Guillaume, Eric Grouzmann, Annick Mühlethaler-Mottet

Published Dec 23, 2020 · Vol. 12, No. 1 · pp. 49-60

Keywords: neuroblastoma, metanephrine, patient-derived xenograft, mouse model, Phenylethanolamine N-Methyltransferase

Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Research Paper

Hector A. Cuello, Gretel M. Ferreira, Cynthia A. Gulino, Alejandro Gomez Toledo, Valeria I. Segatori, Mariano R. Gabri

Published Dec 16, 2020 · Vol. 11, No. 52 · pp. 4822-4835

Keywords: glioma, glioblastoma, Lewis glycans, histone acetylation, N-glycans

Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model Research Paper

Adilson Kleber Ferreira, Brunella Cristofaro, Milene Cristina Menezes, Ana Karina de Oliveira, Alexandre Keiji Tashima, Robson Lopes de Melo, Cristiane Castilho Fernandes Silva, Miryam Guillermina Palomino Rodriguez, Daniela Cajado de Oliveira Souza Carvalho, Ricardo Alexandre de Azevedo, Paulo Luiz de Sá Junior, Lisley Inata Mambelli, Fernanda Vieira Portaro, Luc Pardanaud, Anne Eichmann, Osvaldo Augusto Sant’Anna, Mxarcella Faria

Published Nov 30, 2020 · Vol. 11, No. 51 · pp. 4770-4787

Keywords: alphastatin-C, angiogenesis, peptides, melanoma, angiostatic

Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model Research Paper

Bart Vanderborght, Kevin De Muynck, Sander Lefere, Anja Geerts, Helena Degroote, Xavier Verhelst, Hans Van Vlierberghe, Lindsey Devisscher

Published Nov 24, 2020 · Vol. 11, No. 48 · pp. 4504-4520

Keywords: hepatocellular carcinoma, hypoxia-inducible factor, antisense oligonucleotides, tumor microenvironment, experimental mouse model

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JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer Research Paper

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Correction: Enhanced anti-tumor activity and cytotoxic effect on cancer stem cell population of metformin-butyrate compared with metformin HCl in breast cancer Correction

Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy Research Paper

CEA as a blood-based biomarker in anal cancer Research Paper

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma Research Paper

Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells Research Paper

The interaction between cancer associated fibroblasts and tumor associated macrophages via the osteopontin pathway in the tumor microenvironment of hepatocellular carcinoma Research Paper

MicroRNA-214 enriched exosomes from human cerebral endothelial cells (hCEC) sensitize hepatocellular carcinoma to anti-cancer drugs Research Paper

Krüppel-like factor 4 promotes survival and expansion in acute myeloid leukemia cells Research Paper

Oncolytic virotherapy with SOCS3 enhances viral replicative potency and oncolysis for gastric cancer Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation Research Paper

Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Research Paper

Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model Research Paper

Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer Research Paper

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Correction: Enhanced anti-tumor activity and cytotoxic effect on cancer stem cell population of metformin-butyrate compared with metformin HCl in breast cancer Correction

Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy Research Paper

CEA as a blood-based biomarker in anal cancer Research Paper

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma Research Paper

Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells Research Paper

The interaction between cancer associated fibroblasts and tumor associated macrophages via the osteopontin pathway in the tumor microenvironment of hepatocellular carcinoma Research Paper

MicroRNA-214 enriched exosomes from human cerebral endothelial cells (hCEC) sensitize hepatocellular carcinoma to anti-cancer drugs Research Paper

Krüppel-like factor 4 promotes survival and expansion in acute myeloid leukemia cells Research Paper

Oncolytic virotherapy with SOCS3 enhances viral replicative potency and oncolysis for gastric cancer Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation Research Paper

Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Research Paper

Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model Research Paper

Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model Research Paper