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2,090 results found — showing 101–120

PD-1/PD-L1 expression in anal squamous intraepithelial lesions Research Paper

Margot Bucau, Nathalie Gault, Nanthara Sritharan, Emy Valette, Charlotte Charpentier, Francine Walker, Anne Couvelard, Laurent Abramowitz
Published Sep 17, 2020 · Vol. 11, No. 39 · pp. 3582-3589
Keywords: anal dysplasia, PD-L1, HPV, anal cancer, immune microenvironment

Deconstructing tumor heterogeneity: the stromal perspective Meeting Report

Renee E. Vickman, Douglas V. Faget, Philip Beachy, David Beebe, Neil A. Bhowmick, Edna Cukierman, Wu-Min Deng, James G. Granneman, Jeffrey Hildesheim, Raghu Kalluri, Ken S. Lau, Ernst Lengyel, Joakim Lundeberg, Jorge Moscat, Peter S. Nelson, Kristian Pietras, Katerina Politi, Ellen Puré, Ruth Scherz-Shouval, Mara H. Sherman, David Tuveson, Ashani T. Weeraratna, Richard M. White, Melissa H. Wong, Elisa C. Woodhouse, Ying Zheng, Simon W. Hayward, Sheila A. Stewart
Published Aug 29, 2020 · Vol. 11, No. 40 · pp. 3621-3632
Keywords: tumor microenvironment, stromal heterogeneity, extracellular matrix, cellular plasticity, therapy resistance

Novel combination therapy for melanoma induces apoptosis via a gap junction positive feedback mechanism Research Paper

Archis Bagati, Timothy C. Hutcherson, Zethan Koch, Joseph Pechette, Hossein Dianat, Cory Higley, Lisa Chiu, Yesul Song, Jay Shah, Elana Chazen, Andrew Nicolais, Peter Casey, Kyle Thompson, Kevin Burke, Mikhail A. Nikiforov, Jennifer Zirnheld, Shoshanna N. Zucker
Published Aug 27, 2020 · Vol. 11, No. 37 · pp. 3443-3458
Keywords: non-thermal plasma, gap junction, tirapazamine, melanoma, intercellular communication

Advances in epidermal growth factor receptor specific immunotherapy: lessons to be learned from armed antibodies Review

Fleury Augustin Nsole Biteghe, Neelakshi Mungra, Nyangone Ekome Toung Chalomie, Jean De La Croix Ndong, Jean Engohang-Ndong, Guillaume Vignaux, Eden Padayachee, Krupa Naran, Stefan Barth
Published Aug 26, 2020 · Vol. 11, No. 38 · pp. 3531-3557
Keywords: epidermal growth factor receptor (EGFR), recombinant immunotoxins (ITs), targeted human cytolytic fusion proteins (hCFPs), recombinant antibody-drug conjugates (rADCs), recombinant antibody photoimmunoconjugates (rAPCs)

An integrative microenvironment approach for follicular lymphoma: roles of inflammatory cell subsets and immune-response polymorphisms on disease clinical course Research Paper

Guilherme Rossi Assis-Mendonça, André Fattori, Rafael Malagoli Rocha, Gustavo Jacob Lourenço, Márcia Torresan Delamain, Suely Nonogaki, Vladmir Cláudio Cordeiro de Lima, Gisele Wally Braga Colleoni, Cármino Antonio de Souza, Fernando Augusto Soares, Carmen Silvia Passos Lima, José Vassallo
Published Jul 25, 2020 · Vol. 11, No. 33 · pp. 3153-3173
Keywords: follicular lymphoma, tumor microenvironment, immunohistochemistry, single nucleotide polymorphisms, prognosis

Losartan improves the therapeutic effect of metronomic cyclophosphamide in triple negative mammary cancer models Research Paper

Leandro E. Mainetti, María José Rico, Cintia Daniela Kaufman, Monica Carolina Grillo, Julian Guercetti, María Virginia Baglioni, Antonela Del Giúdice, Maria Celeste Capitani, Matias Fusini, Viviana Rosa Rozados, O. Graciela Scharovsky
Published Jul 22, 2020 · Vol. 11, No. 32 · pp. 3048-3060
Keywords: mammary cancer, metronomic chemotherapy, drug repurposing, cyclophosphamide, losartan

Differentially expressed full-length, fusion and novel isoforms transcripts-based signature of well-differentiated keratinized oral squamous cell carcinoma Research Paper

Neetu Singh, Dinesh Kumar Sahu, Ratnesh Kumar Tripathi, Archana Mishra, Hari Shyam, Pratap Shankar, Mayank Jain, Nawazish Alam, Anil Kumar, Abhishek Mishra, Rebecca Chowdhry, Anjana Singh, Sameer Gupta, Divya Mehrotra, Preeti Agarwal, Madhu Mati Goel, Arun Chaturvedi, Satya Prakash Agarwal, Manish Bajpai, Devendra Kumar Gupta, Madan Lal Brahma Bhatt, Ravi Kant
Published Jul 22, 2020 · Vol. 11, No. 34 · pp. 3227-3243
Keywords: oral tongue squamous cell carcinoma, microarray, transcriptomics, integrative bioinformatics, differentially expressed gene

Clonality and antigen-specific responses shape the prognostic effects of tumor-infiltrating T cells in ovarian cancer Research Paper

Takemasa Tsuji, Kevin H. Eng, Junko Matsuzaki, Sebastiano Battaglia, J. Brian Szender, Anthony Miliotto, Sacha Gnjatic, Wiam Bshara, Carl D. Morrison, Shashikant Lele, Ryan O. Emerson, Jianmin Wang, Song Liu, Harlan Robins, Amit A. Lugade, Kunle Odunsi
Published Jun 23, 2020 · Vol. 11, No. 27 · pp. 2669-2683
Keywords: T-cell repertoire, ovarian cancer, tumor immunity

Rapid onset type 1 diabetes with anti-PD-1 directed therapy Research Paper

Karen Yun, Gregory Daniels, Kathryn Gold, Karen Mccowen, Sandip Pravin Patel
Published Jun 23, 2020 · Vol. 11, No. 28 · pp. 2740-2746
Keywords: type 1 diabetes, diabetic ketoacidosis (DKA), immune-related adverse event (irAE), immunotherapy, PD-1 inhibitors

Renal cell tumors convert natural killer cells to a proangiogenic phenotype Research Paper

Yue Guan, Christopher B. Chambers, Taylor Tabatabai, Ha Hatley, Kristin R. Delfino, Kathy Robinson, Shaheen R. Alanee, Sophia Ran, Donald S. Torry, Andrew Wilber
Published Jun 12, 2020 · Vol. 11, No. 26 · pp. 2571-2585
Keywords: kidney cancer, innate immunity, natural killer cells, immunosuppression, angiogenesis

Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation Research Paper

Ron C. Gaba, Lobna Elkhadragy, F. Edward Boas, Sulalita Chaki, Hanna H. Chen, Mohammed El-Kebir, Kelly D. Garcia, Eileena F. Giurini, Grace Guzman, Francesca V. LoBianco, Mario F. Neto, Jordan L. Newson, Aisha Qazi, Maureen Regan, Lauretta A. Rund, Regina M. Schwind, Matthew C. Stewart, Faith M. Thomas, Herbert E. Whiteley, Jiaqi Wu, Lawrence B. Schook, Kyle M. Schachtschneider
Published Jun 10, 2020 · Vol. 11, No. 28 · pp. 2686-2701
Keywords: liver cancer, transgenic pigs, large animal model, interventional radiology, personalized medicine
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