The Oncosearch | Oncotarget

Real-world evidence to guide healthcare policies in oncology Research Perspective

Marco Donia, Steen Werner Hansen, Inge Marie Svane

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4513-4515

Keywords: real-world evidence, real-world data, clinical trial eligibility

Prognostic immune markers for recurrence and survival in locally advanced esophageal adenocarcinoma Research Paper

Laila Babar, Juliann E. Kosovec, Vida Jahangiri, Nobel Chowdhury, Ping Zheng, Ashten N. Omstead, Madison S. Salvitti, Matthew A. Smith, Ajay Goel, Ronan J. Kelly, Blair A. Jobe, Ali H. Zaidi

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4546-4555

Keywords: esophageal adenocarcinoma, LAG3, IDO1, CXCL9, TIM3

The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment Research Paper

Stephen G. Gaffney, Elizabeth B. Perry, Ping-Min Chen, Andrew Greenstein, Susan M. Kaech, Jeffrey P. Townsend

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4532-4545

Keywords: immunotherapy, tumor microenvironment, T lymphocyte, cancer genomics, RNA-seq

Semi-automated analysis of digital whole slides from humanized lung-cancer xenograft models for checkpoint inhibitor response prediction Research Paper

Daniel Bug, Friedrich Feuerhake, Eva Oswald, Julia Schüler, Dorit Merhof

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4587-4597

Keywords: deep learning, digital pathology, histology, non small cell lung cancer, xenograft

Cystic fibrosis transmembrane conductance regulator (CFTR) and autophagy: hereditary defects in cystic fibrosis versus gluten-mediated inhibition in celiac disease Review

Luigi Maiuri, Valeria Raia, Mauro Piacentini, Antonella Tosco, Valeria Rachela Villella, Guido Kroemer

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4492-4500

Keywords: CFTR, cystic fibrosis, autophagy, celiac disease, transglutaminase 2

CD90^low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer Research Paper

Yang Zeng, Binghao Li, Tao Li, Wei Liu, Chongzhao Ran, Richard T. Penson, Mark C. Poznansky, Yanan Du, Huabiao Chen

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4479-4491

Keywords: mesenchymal stem cells, CD90, ovarian cancer, immunotherapy

Residual disease and immune infiltration as a new surrogate endpoint for TNBC post neoadjuvant chemotherapy Editorial

Stephen L. Luen, Roberto Salgado, Sherene Loi

Published Jul 4, 2019 · Vol. 10, No. 45 · pp. 4612-4614

Keywords: triple negative breast cancer, tumor infiltrating lymphocytes, neoadjuvant chemotherapy, prognosis

The emerging role of human cytomegalovirus infection in human carcinogenesis: a review of current evidence and potential therapeutic implications Review

Cecilia Söderberg Nauclér, Jürgen Geisler, Katja Vetvik

Published Jul 2, 2019 · Vol. 10, No. 42 · pp. 4333-4347

Keywords: human cytomegalovirus, HCMV, oncovirus, cancer, glioblastoma

Cryoablation inhibition of distant untreated tumors (abscopal effect) is immune mediated Research Paper

Xueling Yang, Yongfei Guo, Zhi Guo, Tongguo Si, Wenge Xing, Wenwen Yu, Yan Wang

Published Jun 25, 2019 · Vol. 10, No. 41 · pp. 4180-4191

Constructing personalized longitudinal holoâ€™omes of colon cancer-prone humans and their modeling in flies and mice Review

Myrofora Panagi, Konstantina Georgila, Aristides G. Eliopoulos, Yiorgos Apidianakis

Published Jun 25, 2019 · Vol. 10, No. 41 · pp. 4224-4246

Prevalence of established and emerging biomarkers of immune checkpoint inhibitor response in advanced hepatocellular carcinoma Research Paper

Celina Ang, Samuel J. Klempner, Siraj M. Ali, Russell Madison, Jeffrey S. Ross, Eric A. Severson, David Fabrizio, Aaron Goodman, Razelle Kurzrock, James Suh, Sherri Z. Millis

Published Jun 18, 2019 · Vol. 10, No. 40 · pp. 4018-4025

Keywords: immunotherapy, biomarkers, hepatocellular carcinoma, tumor mutation burden

Immunomodulatory and immunotherapeutic implications of tobacco smoking in squamous cell carcinomas and normal airway epithelium Research Perspective

Jingming Wang, Maximilian Linxweiler, Wei Yang, Timothy A. Chan, Luc G.T. Morris

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3835-3839

Keywords: immune, microenvironment

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall Research Paper

Ann M. Moyer, Jia Yu, Jason P. Sinnwell, Travis J. Dockter, Vera J. Suman, Richard M. Weinshilboum, Judy C. Boughey, Matthew P. Goetz, Daniel W. Visscher, Liewei Wang

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3924-3930

Keywords: patient-derived xenografts, breast cancer, Ki67, NOD-SCID mice, NSG mice

Flow based single cell analysis of the immune landscape distinguishes Barrett’s esophagus from adjacent normal tissue Research Paper

Moen Sen, Friedrich Hahn, Taylor A. Black, Maureen DeMarshall, Warren Porter, Eileen Snowden, Stephanie S. Yee, Frances Tong, Mitchell Ferguson, Emylee N. Fleshman, Hiroshi Nakagawa, Gary W. Falk, Gregory G. Ginsberg, Michael L. Kochman, Rainer Blaesius, Anil K. Rustgi, Erica L. Carpenter

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3592-3604

Keywords: Barrett’s esophagus, microenvironment, immune cells, single cell, flow cytometry

1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours Research Paper

Clare T. Butler, Susan A. Kennedy, Amy Buckley, Ronan Doyle, Emer Conroy, William M. Gallagher, Jacintha O’Sullivan, Breandán N. Kennedy

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3725-3744

Keywords: colorectal cancer, angiogenesis, cysteinyl leukotriene, drug discovery, xenograft

IgG based immunome analyses of breast cancer patients reveal underlying signaling pathways Research Paper

István Gyurján, Sandra Rosskopf, Johana A. Luna Coronell, Daniela Muhr, Christian Singer, Andreas Weinhäusel

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3491-3505

Keywords: protein microarray, immunome, breast cancer, signaling pathways, differentially reactive antigens

Interleukin 1 is a key driver of inflammatory bowel disease-demonstration in a murine IL-1Ra knockout model Research Paper

Rasha H. Dosh, Nicola Jordan-Mahy, Christopher Sammon, Christine Le Maitre

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3559-3575

Keywords: IL-1Ra deficient, inflammatory bowel disease, pro-inflammatory cytokines, matrix-degrading enzymes, intestinal enzymes

Endotoxin tolerance modulates TREG and TH17 lymphocytes protecting septic mice Research Paper

Mariana M.C. Andrade, Suely S.K. Ariga, Denise F. Barbeiro, Hermes V. Barbeiro, Rosangela N. Pimentel, Ricardo C. Petroni, Francisco G. Soriano

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3451-3461

A DNA telomerase vaccine for canine cancer immunotherapy Research Paper

Jessie Thalmensi, Elodie Pliquet, Christelle Liard, Gabriel Chamel, Christine Kreuz, Thomas Bestetti, Marie Escande, Anna Kostrzak, Anne-Sophie Pailhes-Jimenez, Emmanuèle Bourges, Marion Julithe, Ludovic Bourre, Olivier Keravel, Pascal Clayette, Thierry Huet, Simon Wain-Hobson, Pierre Langlade-Demoyen

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3361-3372

Keywords: DNA vaccine, canine TERT, cancer, immunotherapy, Electro-Gene-Transfer

EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis Research Paper

Kelly M. Bailey, Claire M. Julian, Ariel N. Klinghoffer, Heather Bernard, Peter C. Lucas, Linda M. McAllister-Lucas

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3385-3399

Keywords: EWS-FLI1, Ewing sarcoma, T-cell, interferon, apoptosis

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Real-world evidence to guide healthcare policies in oncology Research Perspective

Prognostic immune markers for recurrence and survival in locally advanced esophageal adenocarcinoma Research Paper

The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment Research Paper

Semi-automated analysis of digital whole slides from humanized lung-cancer xenograft models for checkpoint inhibitor response prediction Research Paper

Cystic fibrosis transmembrane conductance regulator (CFTR) and autophagy: hereditary defects in cystic fibrosis versus gluten-mediated inhibition in celiac disease Review

CD90^low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer Research Paper

Residual disease and immune infiltration as a new surrogate endpoint for TNBC post neoadjuvant chemotherapy Editorial

The emerging role of human cytomegalovirus infection in human carcinogenesis: a review of current evidence and potential therapeutic implications Review

Cryoablation inhibition of distant untreated tumors (abscopal effect) is immune mediated Research Paper

Constructing personalized longitudinal holoâ€™omes of colon cancer-prone humans and their modeling in flies and mice Review

Prevalence of established and emerging biomarkers of immune checkpoint inhibitor response in advanced hepatocellular carcinoma Research Paper

Immunomodulatory and immunotherapeutic implications of tobacco smoking in squamous cell carcinomas and normal airway epithelium Research Perspective

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall Research Paper

Flow based single cell analysis of the immune landscape distinguishes Barrett’s esophagus from adjacent normal tissue Research Paper

1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours Research Paper

IgG based immunome analyses of breast cancer patients reveal underlying signaling pathways Research Paper

Interleukin 1 is a key driver of inflammatory bowel disease-demonstration in a murine IL-1Ra knockout model Research Paper

Endotoxin tolerance modulates TREG and TH17 lymphocytes protecting septic mice Research Paper

A DNA telomerase vaccine for canine cancer immunotherapy Research Paper

EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Real-world evidence to guide healthcare policies in oncology Research Perspective

Prognostic immune markers for recurrence and survival in locally advanced esophageal adenocarcinoma Research Paper

The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment Research Paper

Semi-automated analysis of digital whole slides from humanized lung-cancer xenograft models for checkpoint inhibitor response prediction Research Paper

Cystic fibrosis transmembrane conductance regulator (CFTR) and autophagy: hereditary defects in cystic fibrosis versus gluten-mediated inhibition in celiac disease Review

CD90low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer Research Paper

Residual disease and immune infiltration as a new surrogate endpoint for TNBC post neoadjuvant chemotherapy Editorial

The emerging role of human cytomegalovirus infection in human carcinogenesis: a review of current evidence and potential therapeutic implications Review

Cryoablation inhibition of distant untreated tumors (abscopal effect) is immune mediated Research Paper

Constructing personalized longitudinal holoâ€™omes of colon cancer-prone humans and their modeling in flies and mice Review

Prevalence of established and emerging biomarkers of immune checkpoint inhibitor response in advanced hepatocellular carcinoma Research Paper

Immunomodulatory and immunotherapeutic implications of tobacco smoking in squamous cell carcinomas and normal airway epithelium Research Perspective

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall Research Paper

Flow based single cell analysis of the immune landscape distinguishes Barrett’s esophagus from adjacent normal tissue Research Paper

1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours Research Paper

IgG based immunome analyses of breast cancer patients reveal underlying signaling pathways Research Paper

Interleukin 1 is a key driver of inflammatory bowel disease-demonstration in a murine IL-1Ra knockout model Research Paper

Endotoxin tolerance modulates TREG and TH17 lymphocytes protecting septic mice Research Paper

A DNA telomerase vaccine for canine cancer immunotherapy Research Paper

EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis Research Paper

CD90^low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer Research Paper