The Oncosearch | Oncotarget

Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival Research Paper

Saif Zaman, Fred S. Gorelick, Andrea Chrobrutskiy, Boris I. Chobrutskiy, Gary V. Desir, George Blanck

Published Jul 20, 2024 · Vol. 15, No. 1 · pp. 550-561

Keywords: RNLS, melanoma, T-cell receptor CDR3s, chemical complementarity

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma Research Paper

Caroline Naomi Valdez, Gabriela Athziri Sánchez-Zuno, Lais Osmani, Wael Ibrahim, Anjela Galan, Antonietta Bacchiocchi, Ruth Halaban, Rajan P. Kulkarni, Insoo Kang, Richard Bucala, Thuy Tran

Published Jul 15, 2024 · Vol. 15, No. 1 · pp. 507-520

Keywords: MIF, DDT, melanoma, immune checkpoint inhibition, cancer transcriptomics

Strategies to disrupt NKG2A:HLA-E interactions for improved anti-cancer immunity Editorial

Jack G. Fisher, Lara V. Graham, Matthew D. Blunt

Published Jul 5, 2024 · Vol. 15, No. 1 · pp. 501-503

Keywords: Natural killer (NK) cells, immunotherapy, NKG2A, immune checkpoint blockade, HLA-E

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

Chantal L. Duurland, Thijs de Gunst, Harm C. den Boer, Marion T.J. van den Bosch, Bryony J. Telford, Rogier M. Vos, Xiaolei Xie, Mingfa Zang, Fang Wang, Yingying Shao, Xiaoyu An, Jingjing Wang, Jie Cai, Ludovic Bourré, Laurens A.H. van Pinxteren, Roel Q.J. Schaapveld, Michel Janicot, Sanaz Yahyanejad

Published Jul 4, 2024 · Vol. 15, No. 1 · pp. 470-485

Keywords: miR-193a-3p, microRNA mimic, T cell mediated immunity, immunogenic cell death, cancer

Starving cancer cells to enhance DNA damage and immunotherapy response Research Perspective

Aashirwad Shahi, Dawit Kidane

Published Jun 12, 2024 · Vol. 15, No. 1 · pp. 392-399

Keywords: amino acid depletion, DNA damage, DNA repair, Immunotherapy, tumor immunity

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response Research Paper

Lulzim Shkreta, Johanne Toutant, Aurélie Delannoy, David Durantel, Anna Salvetti, Sophie Ehresmann, Martin Sauvageau, Julien A. Delbrouck, Alice Gravel-Trudeau, Christian Comeau, Caroline Huard, Jasmin Coulombe-Huntington, Mike Tyers, David Grierson, Pierre-Luc Boudreault, Benoit Chabot

Published May 9, 2024 · Vol. 15, No. 1 · pp. 313-325

Keywords: CLK kinases inhibitors, EMT, antiviral immune response, microtubules, metastasis

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer Research Paper

Haven R. Garber, Sreyashi Basu, Sonali Jindal, Zhong He, Khoi Chu, Akshara Singareeka Raghavendra, Clinton Yam, Lumarie Santiago, Beatriz E. Adrada, Padmanee Sharma, Elizabeth A. Mittendorf, Jennifer K. Litton

Published Mar 2, 2024 · Vol. 15, No. 1 · pp. 238-247

Keywords: breast cancer, ER positive, immunotherapy, neoadjuvant chemotherapy, tumor microenvironment

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines Research Paper

Mathew Lozinski, Nikola A. Bowden, Moira C. Graves, Michael Fay, Bryan W. Day, Brett W. Stringer, Paul A. Tooney

Published Jan 5, 2024 · Vol. 15, No. 1 · pp. 1-18

Keywords: glioblastoma, DNA damage response, ataxia-telangiectasia and rad3-related protein, radiation therapy, temozolomide

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma Research Perspective

Ashley Del Dosso, Elizabeth Tadevosyan, James R. Berenson

Published Dec 23, 2023 · Vol. 15, No. 1 · pp. 65-75

Keywords: multiple myeloma, ruxolitinib, JAK/STAT, cytokine, clinical trial

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation Research Perspective

Mark Lee, Luc GT Morris

Published Dec 15, 2023 · Vol. 15, No. 1 · pp. 36-48

Keywords: thyroid cancer, drug resistance, anaplastic transformation, BRAF inhibitors, PIK3CA

FAAH inhibition ameliorates breast cancer in a murine model Research Paper

Mallika Tripathy, Amy Bui, Jared Henderson, Jeffrey Sun, Christian Rutan Woods, Soumya Somani, Thao Doan, Anto Sam Crosslee Louis Sam Titus, Chandra Mohan

Published Oct 26, 2023 · Vol. 14, No. 1 · pp. 910-918

Keywords: FAAH, breast cancer, cancer therapy, apoptosis

Correction: Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis Correction

Dominique Thuringer, Gaetan Jego, Kevin Berthenet, Arlette Hammann, Eric Solary, Carmen Garrido

Published Oct 6, 2023 · Vol. 15, No. 1 · pp. 285-287

Peripheral surrogates of tumor burden to guide chemotherapeutic and immunotherapeutic strategies for HPV-associated malignancies Review

Meghali Goswami, Jeffrey Schlom, Renee N. Donahue

Published Aug 3, 2023 · Vol. 14, No. 1 · pp. 758-774

Keywords: HPV-associated malignancies, immunotherapy, circulating tumor DNA, circulating tumor cells, HPV-specific antibodies

Addendum: Immune-related adverse events and atypical radiological response with checkpoint inhibitor immunotherapy in an elderly patient with high PD-L1 expressing lung adenocarcinoma Addendum

Eduard Teixidor, Elia Sais, Carmen Amalia Vásquez, Walter Carbajal, Alejandro Hernández, Gloria Sánchez, Angel Izquierdo, Sara Verdura, Javier A. Menéndez, Joaquim Bosch-Barrera

Published Jun 27, 2023 · Vol. 14, No. 1 · pp. 668-668

Transformation of immunosuppressive mtKRAS tumors into immunostimulatory tumors by Nerofe and Doxorubicin Research Paper

Joel Ohana, Uziel Sandler, Orly Devary, Yoram Devary

Published Jun 20, 2023 · Vol. 14, No. 1 · pp. 688-699

Keywords: Colorectal cancer, KRAS, apoptosis, hormone peptide, endoplasmic reticulum stress

Targeting GITR in cancer immunotherapy – there is no perfect knowledge Research Perspective

Diwakar Davar, Roberta Zappasodi

Published Jun 12, 2023 · Vol. 14, No. 1 · pp. 614-621

Keywords: cancer, immunotherapy, programmed death-1 (PD-1), cytotoxic T-lymphocyte Antigen-4 (CTLA-4), glucocorticoid-induced TNFR-related protein (GITR)

Inhibition of glutamine metabolism: acting on tumoral cells or on tumor microenvironment? Editorial

Raul Peña

Published May 16, 2023 · Vol. 14, No. 1 · pp. 755-757

Keywords: glutamine, tumor microenvironment, fibroblasts, CAF, snail1

Correction: Changes in the cellular immune system and circulating inflammatory markers of stroke patients Correction

Chao Jiang, Weixia Kong, Yuejuan Wang, Wendy Ziai, Qingwu Yang, Fangfang Zuo, Fangfang Li, Yali Wang, Hongwei Xu, Qian Li, Jie Yang, Hong Lu, Jiewen Zhang, Jian Wang

Published Apr 27, 2023

The critical immune basis for differential responses to immunotherapy in primary versus metastatic pancreatic cancer Editorial

Brian Diskin, Sarah Schwartz, George Miller

Published Feb 16, 2023 · Vol. 14, No. 1 · pp. 364-365

Keywords: pancreatic cancer, liver metastasis, immunnotherapy

Proof-of-principle: targeted childhood leukemia prevention Editorial

César Cobaleda, Manuel Ramírez-Orellana, Carolina Vicente-Dueñas, Andreas Weiss, Kim E. Nichols, Isidro Sánchez-García

Published Feb 16, 2023 · Vol. 14, No. 1 · pp. 190-192

Keywords: leukemia, infection, murine models, genetic susceptibility, prevention

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Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival Research Paper

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma Research Paper

Strategies to disrupt NKG2A:HLA-E interactions for improved anti-cancer immunity Editorial

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

Starving cancer cells to enhance DNA damage and immunotherapy response Research Perspective

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response Research Paper

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer Research Paper

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines Research Paper

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma Research Perspective

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation Research Perspective

FAAH inhibition ameliorates breast cancer in a murine model Research Paper

Correction: Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis Correction

Peripheral surrogates of tumor burden to guide chemotherapeutic and immunotherapeutic strategies for HPV-associated malignancies Review

Addendum: Immune-related adverse events and atypical radiological response with checkpoint inhibitor immunotherapy in an elderly patient with high PD-L1 expressing lung adenocarcinoma Addendum

Transformation of immunosuppressive mtKRAS tumors into immunostimulatory tumors by Nerofe and Doxorubicin Research Paper

Targeting GITR in cancer immunotherapy – there is no perfect knowledge Research Perspective

Inhibition of glutamine metabolism: acting on tumoral cells or on tumor microenvironment? Editorial

Correction: Changes in the cellular immune system and circulating inflammatory markers of stroke patients Correction

The critical immune basis for differential responses to immunotherapy in primary versus metastatic pancreatic cancer Editorial

Proof-of-principle: targeted childhood leukemia prevention Editorial

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival Research Paper

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma Research Paper

Strategies to disrupt NKG2A:HLA-E interactions for improved anti-cancer immunity Editorial

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

Starving cancer cells to enhance DNA damage and immunotherapy response Research Perspective

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response Research Paper

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer Research Paper

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines Research Paper

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma Research Perspective

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation Research Perspective

FAAH inhibition ameliorates breast cancer in a murine model Research Paper

Correction: Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis Correction

Peripheral surrogates of tumor burden to guide chemotherapeutic and immunotherapeutic strategies for HPV-associated malignancies Review

Addendum: Immune-related adverse events and atypical radiological response with checkpoint inhibitor immunotherapy in an elderly patient with high PD-L1 expressing lung adenocarcinoma Addendum

Transformation of immunosuppressive mtKRAS tumors into immunostimulatory tumors by Nerofe and Doxorubicin Research Paper

Targeting GITR in cancer immunotherapy – there is no perfect knowledge Research Perspective

Inhibition of glutamine metabolism: acting on tumoral cells or on tumor microenvironment? Editorial

Correction: Changes in the cellular immune system and circulating inflammatory markers of stroke patients Correction

The critical immune basis for differential responses to immunotherapy in primary versus metastatic pancreatic cancer Editorial

Proof-of-principle: targeted childhood leukemia prevention Editorial