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2,090 results found
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COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review
Keywords: COVID, vaccine, cancer, infection, lymphoma, leukemia, sarcoma, carcinoma
Exploring the potential link between mRNA COVID-19 vaccinations and cancer: A case report with a review of haematopoietic malignancies with insights into pathogenic mechanisms Case Report
Keywords: COVID-19 genetic vaccines, adverse effects, cancer, lymphoblastic leukaemia, lymphoblastic lymphoma
Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper
Keywords: mutant KRAS, Nerofe, ST2 Receptor, tumor immune microenvironment, nuclear immunomodulation
ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response Research Paper
Keywords: tumor microenvironment, bacterial vector, myeloid cells, STING, IL-15
Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper
Keywords: high-grade serous ovarian carcinoma, orthotopic models, inflammation, microenvironment
A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment Research Paper
Keywords: Treg, CD25, TME, mAb, GVHD
Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors Review
Keywords: CHEK2 , immune checkpoint inhibitors, immunomodulation
Molecular landscape of HER2-mutated non-small cell lung cancer in Northeastern Brazil: Clinical, histopathological, and genomic insights Research Paper
Keywords: HER2 mutation, NSCLC, lung cancer, targeted therapy, genomic profiling
Advancements in bladder cancer treatment: The synergy of radiation and immunotherapy Review
Keywords: bladder cancer, immunotherapy, radiation, microenvironment, abscopal
Immune-mediated adverse events following atezolizumab and bevacizumab in a multinational Latin American cohort of unresectable hepatocellular carcinoma Research Paper
Keywords: liver cancer, immunotherapy, adverse events, immunology, real-world
PD-L1 and FOXP3 expression in high-grade squamous intraepithelial lesions of the anogenital region Research Paper
Keywords: HPV, high-grade intraepithelial lesion, immune evasion, PD-L1, FOXP3
Worldwide Innovative Network (WIN) Consortium in Personalized Cancer Medicine: Bringing next-generation precision oncology to patients Precision Oncology
Keywords: precision oncology, N-of-1 basket trials, AI algorithms, digital pathology, drug access
Signaling pathway dysregulation in breast cancer Review
Keywords: breast cancer, oncogenic pathways, signal dysregulation in cancer, therapeutic approaches, clinical trials
Mesenchymal stem cells - the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists Review
Keywords: mesenchymal stem cells, genetic engineering, cancer immunotherapy, mesenchymal stem cell homing, stem cell delivery
Understanding the interplay between extracellular matrix topology and tumor-immune interactions: Challenges and opportunities Review
Keywords: ECM, tumor-T cell evolution, tumor microenvironment
A case of adenosquamous pancreatic cancer with a KRAS G12C mutation with an exceptional response to immunotherapy Case Report
Keywords: pancreatic cancer, immunotherapy, metastasis
Linking FOXM1 and PD-L1 to CDK4/6-MEK targeted therapy resistance in malignant peripheral nerve sheath tumors Mini-Review
Keywords: MPNST, FOXM1, PD-L1, CDK4/6-MEK targeting, therapy resistance
UBA1 dysfunction in VEXAS and cancer Research Perspective
Keywords: VEXAS, MDS, clonal cytopenia, ubiquitin, inflammation
Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche Research Perspective
Keywords: hematopoietic stem and progenitor cells, acute myeloid leukemia, inflammation, innate immune reprogramming, trained immunity