The Oncosearch | Oncotarget

p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia Priority Research Paper

Alper Yetil, Benedict Anchang, Arvin M. Gouw, Stacey J. Adam, Tahera Zabuawala, Ramya Parameswaran, Jan van Riggelen, Sylvia Plevritis, Dean W. Felsher

Published Jan 13, 2015 · Vol. 6, No. 6 · pp. 3563-3577

Cyclosporine A and tacrolimus inhibit bladder cancer growth through down-regulation of NFATc1 Research Paper

Takashi Kawahara, Eiji Kashiwagi, Hiroki Ide, Yi Li, Yichun Zheng, Yurina Miyamoto, George J. Netto, Hitoshi Ishiguro, Hiroshi Miyamoto

Published Jan 8, 2015 · Vol. 6, No. 3 · pp. 1582-1593

Keywords: bladder cancer, cyclosporine, NFAT, tacrolimus, tumor progression

IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment Research Paper

Jon N Buzzelli, Dan I Pavlic, Heather V Chalinor, Louise Oâ€™Connor, Trevelyan R Menheniott, Andrew S Giraud, Louise M Judd

Published Jan 6, 2015 · Vol. 6, No. 2 · pp. 679-695

Keywords: Mucosal immunity, cancer immunobiology, cytokines, IL-11, STAT3, IL-1, MDSCs

Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors Research Paper

Sebastian SchÃ¶lch, Conrad Rauber, Alexandra Tietz, Nuh N. Rahbari, Ulrich Bork, Thomas Schmidt, Christoph Kahlert, Uwe Haberkorn, Mark A. Tomai, Kenneth E. Lipson, Rafael Carretero, JÃ¼rgen Weitz, Moritz Koch, Peter E. Huber

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4663-4676

Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma Research Paper

Ziming Du, Malak Abedalthagafi, Ayal A. Aizer, Allison R. McHenry, Heather H. Sun, Mark-Anthony Bray, Omar Viramontes, Revaz Machaidze, Priscilla K. Brastianos, David A. Reardon, Ian F. Dunn, Gordon J. Freeman, Keith L. Ligon, Anne E. Carpenter, Brian M. Alexander, Nathalie Y. Agar, Scott J. Rodig, Elizabeth M. Bradshaw, Sandro Santagata

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4704-4716

Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma Research Paper

Iris Chiara Salaroglio, Ivana Campia, Joanna Kopecka, Elena Gazzano, Sara Orecchia, Dario Ghigo, Chiara Riganti

Published Dec 31, 2014 · Vol. 6, No. 2 · pp. 1128-1142

Keywords: malignant mesothelioma, chemoresistance, P-glycoprotein, immunosuppression, indoleamine 1, 2 dioxygenase, zoledronic acid

Prognostic and predictive value of PDL1 expression in breast cancer Clinical Research Papers

Renaud Sabatier, Pascal Finetti, Emilie Mamessier, JosÃ© Adelaide, Max Chaffanet, Hamid Raza Ali, Patrice Viens, Carlos Caldas, Daniel Birnbaum, FranÃ§ois Bertucci

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5449-5464

Targeting the tumor microenvironment to enhance antitumor immune responses Review

Kevin Van der Jeught, Lukasz Bialkowski, Lidia Daszkiewicz, Katrijn Broos, Cleo Goyvaerts, Dries Renmans, Sandra Van Lint, Carlo Heirman, Kris Thielemans, Karine Breckpot

Published Dec 26, 2014 · Vol. 6, No. 3 · pp. 1359-1381

In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma Research Paper

Ken Maes, Eva De Smedt, Alboukadel Kassambara, Dirk Hose, Anja Seckinger, Els Van Valckenborgh, Eline Menu, Bernard Klein, Karin Vanderkerken, JÃ©rÃ´me Moreaux, Elke De Bruyne

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3319-3334

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor Research Paper

Loredana Vesci, Elena Bernasconi, Ferdinando Maria Milazzo, Rita De Santis, Eugenio Gaudio, Ivo Kwee, Andrea Rinaldi, Silvia Pace, Valeria Carollo, Giuseppe Giannini, Francesco Bertoni

Published Dec 25, 2014 · Vol. 6, No. 8 · pp. 5735-5748

Classification of current anticancer immunotherapies Review

Lorenzo Galluzzi, Erika Vacchelli, JosÃ©-Manuel Bravo-San Pedro, Aitziber BuquÃ©, Laura Senovilla, Elisa Elena Baracco, Norma Bloy, Francesca Castoldi, Jean-Pierre Abastado, Patrizia Agostinis, Ron N. Apte, Fernando Aranda, Maha Ayyoub, Philipp Beckhove, Jean-Yves Blay, Laura Bracci, Anne Caignard, Chiara Castelli, Federica Cavallo, Estaban Celis, Vincenzo Cerundolo, Aled Clayton, Mario P. Colombo, Lisa Coussens, Madhav V. Dhodapkar, Alexander M. Eggermont, Douglas T. Fearon, Wolf H. Fridman, Jitka FuÄÃkovÃ¡, Dmitry I. Gabrilovich, JÃ©rÃ´me Galon, Abhishek Garg, FranÃ§ois Ghiringhelli, Giuseppe Giaccone, Eli Gilboa, Sacha Gnjatic, Axel Hoos, Anne Hosmalin, Dirk JÃ¤ger, Pawel Kalinski, Klas KÃ¤rre, Oliver Kepp, Rolf Kiessling, John M. Kirkwood, Eva Klein, Alexander Knuth, Claire E. Lewis, Roland Liblau, Michael T. Lotze, Enrico Lugli, Jean-Pierre Mach, Fabrizio Mattei, Domenico Mavilio, Ignacio Melero, Cornelis J. Melief, Elizabeth A. Mittendorf, Lorenzo Moretta, Adekunke Odunsi, Hideho Okada, Anna Karolina Palucka, Marcus E. Peter, Kenneth J. Pienta, Angel Porgador, George C. Prendergast, Gabriel A. Rabinovich, Nicholas P. Restifo, Naiyer Rizvi, Catherine SautÃ¨s-Fridman, Hans Schreiber, Barbara Seliger, Hiroshi Shiku, Bruno Silva-Santos, Mark J. Smyth, Daniel E. Speiser, Radek Spisek, Pramod K. Srivastava, James E. Talmadge, Eric Tartour, Sjoerd H. Van Der Burg, BenoÃ®t J. Van Den Eynde, Richard Vile, Hermann Wagner, JeffreyÂ S. Weber, Theresa L. Whiteside, Jedd D. Wolchok, Laurence Zitvogel, Weiping Zou, Guido Kroemer

Published Dec 18, 2014 · Vol. 5, No. 24 · pp. 12472-12508

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy Research Paper

Aaron Raymond, Bin Liu, Hong Liang, Ciamaio Wei, Michele Guindani, Yue Lu, Shoudan Liang, Lisa S. St. John, Jeff Molldrem, Lalitha Nagarajan

Published Dec 17, 2014 · Vol. 5, No. 24 · pp. 12675-12693

The TLR7 agonist induces tumor regression both by promoting CD4+T cells proliferation and by reversing T regulatory cell-mediated suppression via dendritic cells Research Paper

Chenchen Wang, Quan Zhou, Xiaofeng Wang, Xiongyan Wu, Xuehua Chen, Jianfang Li, Zhenggang Zhu, Bingya Liu, Liping Su

Published Dec 15, 2014 · Vol. 6, No. 3 · pp. 1779-1789

Keywords: TLR7, Treg cells, Immune suppression, Anti-tumor effect

Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/Î²-catenin pathway Research Paper

Dong Li, Wenfan Liu, Xuan Wang, Junlu Wu, Wenqiang Quan, Yiwen Yao, Robert Bals, Shurong Ji, Kaiyin Wu, Jia Guo, Haiying Wan

Published Dec 15, 2014 · Vol. 6, No. 5 · pp. 2939-2950

Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration Research Paper

Timothy J. Zumwalt, Mildred Arnold, Ajay Goel, C. Richard Boland

Published Dec 11, 2014 · Vol. 6, No. 5 · pp. 2981-2991

Inhibition of HIF-1Î± by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Research Paper

Tiansuo Zhao, He Ren, Li Jia, Jing Chen, Wen Xin, Fan Yan, Jing Li, Xiuchao Wang, Song Gao, Dong Qian, Chongbiao Huang, Jihui Hao

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2250-2262

Targeting of TGF-Î²-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer Research Paper

Hui-Ling Huang, Chi-Hsiang Chiang, Wen-Chun Hung, Ming-Feng Hou

Published Dec 10, 2014 · Vol. 6, No. 2 · pp. 995-1007

Keywords: TGF-Î²-activated protein kinase 1 (TAK1), TAK1 binding proteins (TABs), chemokine (C-C motif) receptor 7 (CCR7), NF-ÎºB, c-JUN, lymphatic invasion

The antimicrobial peptide pardaxin exerts potent anti-tumor activity against canine perianal gland adenoma Research Paper

Chieh-Yu Pan, Chao-Nan Lin, Ming-Tang Chiou, Chao Yuan Yu, Jyh-Yih Chen, Chi-Hsien Chien

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2290-2301

Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells Research Paper

Bo-Ra Lee, Sun-Young Chang, Eun-Hye Hong, Bo-Eun Kwon, Hong Min Kim, Yeon-Jeong Kim, Jongkook Lee, Hyun-Jong Cho, Jae-Hee Cheon, Hyun-Jeong Ko

Published Dec 2, 2014 · Vol. 5, No. 23 · pp. 12331-12345

Keywords: cancer, ER stress, MDSC, immunosuppression, arginase-1

Dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma Research Paper

Chunyan Li, Gang Meng, Lei Su, Aiping Chen, Mao Xia, Chun Xu, Decai Yu, Aiqin Jiang, Jiwu Wei

Published Dec 2, 2014 · Vol. 6, No. 3 · pp. 1544-1555

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia Priority Research Paper

Cyclosporine A and tacrolimus inhibit bladder cancer growth through down-regulation of NFATc1 Research Paper

IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment Research Paper

Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors Research Paper

Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma Research Paper

Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma Research Paper

Prognostic and predictive value of PDL1 expression in breast cancer Clinical Research Papers

Targeting the tumor microenvironment to enhance antitumor immune responses Review

In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma Research Paper

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor Research Paper

Classification of current anticancer immunotherapies Review

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy Research Paper

The TLR7 agonist induces tumor regression both by promoting CD4+T cells proliferation and by reversing T regulatory cell-mediated suppression via dendritic cells Research Paper

Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/Î²-catenin pathway Research Paper

Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration Research Paper

Inhibition of HIF-1Î± by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Research Paper

Targeting of TGF-Î²-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer Research Paper

The antimicrobial peptide pardaxin exerts potent anti-tumor activity against canine perianal gland adenoma Research Paper

Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells Research Paper

Dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia Priority Research Paper

Cyclosporine A and tacrolimus inhibit bladder cancer growth through down-regulation of NFATc1 Research Paper

IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment Research Paper

Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors Research Paper

Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma Research Paper

Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma Research Paper

Prognostic and predictive value of PDL1 expression in breast cancer Clinical Research Papers

Targeting the tumor microenvironment to enhance antitumor immune responses Review

In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma Research Paper

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor Research Paper

Classification of current anticancer immunotherapies Review

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy Research Paper

The TLR7 agonist induces tumor regression both by promoting CD4+T cells proliferation and by reversing T regulatory cell-mediated suppression via dendritic cells Research Paper

Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/Î²-catenin pathway Research Paper

Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration Research Paper

Inhibition of HIF-1Î± by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Research Paper

Targeting of TGF-Î²-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer Research Paper

The antimicrobial peptide pardaxin exerts potent anti-tumor activity against canine perianal gland adenoma Research Paper

Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells Research Paper

Dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma Research Paper