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A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. Mc Nulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Dec 16, 2019

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. Mc Nulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Dec 16, 2019

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. Mc Nulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Dec 16, 2019

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

The emerging role of human cytomegalovirus infection in human carcinogenesis: a review of current evidence and potential therapeutic implications Review

Cecilia Söderberg Nauclér, Jürgen Geisler, Katja Vetvik

Published Jul 2, 2019 · Vol. 10, No. 42 · pp. 4333-4347

Keywords: human cytomegalovirus, HCMV, oncovirus, cancer, glioblastoma

Differential microglia and macrophage profiles in human IDH-mutant and -wild type glioblastoma Research Paper

Candice C. Poon, Paul M.K. Gordon, Katherine Liu, Runze Yang, Susobhan Sarkar, Reza Mirzaei, Shiekh Tanveer Ahmad, Martha L. Hughes, V. Wee Yong, John J.P. Kelly

Published May 3, 2019 · Vol. 10, No. 33 · pp. 3129-3143

A novel anti-melanoma SRC-family kinase inhibitor Research Paper

Ruth Halaban, Antonella Bacchiocchi, Robert Straub, Jian Cao, Mario Sznol, Deepak Narayan, Ahmed Allam, Michael Krauthammer, Tarek S. Mansour

Published Mar 19, 2019 · Vol. 10, No. 23 · pp. 2237-2251

Keywords: melanoma, SRC-family kinase inhibitors, MAPK, MITF

FGF2-FGFR1 pathway activation together with thymidylate synthase upregulation is induced in pemetrexed-resistant lung cancer cells Research Paper

Kentaro Miura, Takaaki Oba, Kazutoshi Hamanaka, Ken-ichi Ito

Published Feb 5, 2019 · Vol. 10, No. 11 · pp. 1171-1192

Immunonutritional consequences of different serine-type protease inhibitors in a C57BL/6 hepatocarcinoma model Research Paper

Jose Laparra, Bartosz Fotschki, Claudia Haros

Published Jan 22, 2019 · Vol. 10, No. 7 · pp. 760-772

Genetically coating oncolytic herpes simplex virus with CD47 allows efficient systemic delivery and prolongs virus persistence at tumor site Research Paper

Xinping Fu, Lihua Tao, Xiaoliu Zhang

Published Oct 2, 2018 · Vol. 9, No. 77 · pp. 34543-34553

The double stranded RNA analog poly-IC elicits both robust IFN-Î» production and oncolytic activity in human gastrointestinal cancer cells Research Paper

Chantal Bou-Hanna, Anne Jarry, Jean-FranÃ§ois Mosnier, CÃ©line Bossard, Christian L. Laboisse

Published Oct 2, 2018 · Vol. 9, No. 77 · pp. 34471-34484

Intestinal epithelial Notch-1 protects from colorectal mucinous adenocarcinoma Research Paper

David Dunkin, Alina C. Iuga, Sanda Mimouna, Carolyn L. Harris, Jean-Vianney Haure-Mirande, Dominique Bozec, Garabet Yeretssian, Stephanie Dahan

Published Sep 11, 2018 · Vol. 9, No. 71 · pp. 33536-33548

Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy Review

Jack W. Singer, Angela Fleischman, Suliman Al-Fayoumi, John O. Mascarenhas, Qiang Yu, Anupriya Agarwal

Published Sep 7, 2018 · Vol. 9, No. 70 · pp. 33416-33439

Cell-specific plasticity associated with integrative memory of triple sensory signals in the barrel cortex Research Paper

Jing Feng, Wei Lu, Guang-Yan Wang, Zhao-Ming Zhu, Yan Sun, Kaixin Du, Jin-Hui Wang

Published Jul 24, 2018 · Vol. 9, No. 57 · pp. 30962-30978

The inhibition of malignant melanoma cell invasion of bone by the TLR7 agonist R848 is dependent upon pro-inflammatory cytokines produced by bone marrow macrophages Research Paper

Yoko Manome, Dai Suzuki, Ayako Mochizuki, Emi Saito, Kiyohito Sasa, Kentaro Yoshimura, Tomio Inoue, Masamichi Takami, Katsunori Inagaki, Takahiro Funatsu, Ryutaro Kamijo

Published Jul 6, 2018 · Vol. 9, No. 52 · pp. 29934-29943

Harnessing RIG-I and intrinsic immunity in the tumor microenvironment for therapeutic cancer treatment Review

David L. Elion, Rebecca S. Cook

Published Jun 22, 2018 · Vol. 9, No. 48 · pp. 29007-29017

Lysis-independent potentiation of immune checkpoint blockade by oncolytic virus Research Paper

Anton Oseledchyk, Jacob M. Ricca, Mathieu Gigoux, Brian Ko, Gil Redelman-Sidi, Tyler Walther, Cailian Liu, Gopa Iyer, Taha Merghoub, Jedd D. Wolchok, Dmitriy Zamarin

Published Jun 19, 2018 · Vol. 9, No. 47 · pp. 28702-28716

PD-L1 is expressed on human platelets and is affected by immune checkpoint therapy Research Paper

Verena Rolfes, Christian Idel, Ralph Pries, Kirstin PlÃ¶tze-Martin, Jens Habermann, Timo Gemoll, Sabine Bohnet, Eicke Latz, Julika Ribbat-Idel, Bernardo S. Franklin, Barbara Wollenberg

Published Jun 8, 2018 · Vol. 9, No. 44 · pp. 27460-27470

Prognostic values of the mRNA expression of natural killer receptor ligands and their association with clinicopathological features in breast cancer patients Research Paper

Ali Abouelghar, Reem Hasnah, Ghina Taouk, Mohamad Saad, Manale Karam

Published Jun 5, 2018 · Vol. 9, No. 43 · pp. 27171-27196

Development of a preclinical humanized mouse model to evaluate acute toxicity of an influenza vaccine Research Paper

Eita Sasaki, Haruka Momose, Yuki Hiradate, Keiko Furuhata, Takuo Mizukami, Isao Hamaguchi

Published May 25, 2018 · Vol. 9, No. 40 · pp. 25751-25763

Development of a cell-based assay to identify hepatitis B virus entry inhibitors targeting the sodium taurocholate cotransporting polypeptide Research Paper

Kei Miyakawa, Satoko Matsunaga, Yutaro Yamaoka, Mina Dairaku, Kento Fukano, Hirokazu Kimura, Tomoyuki Chimuro, Hironori Nishitsuji, Koichi Watashi, Kunitada Shimotohno, Takaji Wakita, Akihide Ryo

Published May 4, 2018 · Vol. 9, No. 34 · pp. 23681-23694

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A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

The emerging role of human cytomegalovirus infection in human carcinogenesis: a review of current evidence and potential therapeutic implications Review

Differential microglia and macrophage profiles in human IDH-mutant and -wild type glioblastoma Research Paper

A novel anti-melanoma SRC-family kinase inhibitor Research Paper

FGF2-FGFR1 pathway activation together with thymidylate synthase upregulation is induced in pemetrexed-resistant lung cancer cells Research Paper

Immunonutritional consequences of different serine-type protease inhibitors in a C57BL/6 hepatocarcinoma model Research Paper

Genetically coating oncolytic herpes simplex virus with CD47 allows efficient systemic delivery and prolongs virus persistence at tumor site Research Paper

The double stranded RNA analog poly-IC elicits both robust IFN-Î» production and oncolytic activity in human gastrointestinal cancer cells Research Paper

Intestinal epithelial Notch-1 protects from colorectal mucinous adenocarcinoma Research Paper

Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy Review

Cell-specific plasticity associated with integrative memory of triple sensory signals in the barrel cortex Research Paper

The inhibition of malignant melanoma cell invasion of bone by the TLR7 agonist R848 is dependent upon pro-inflammatory cytokines produced by bone marrow macrophages Research Paper

Harnessing RIG-I and intrinsic immunity in the tumor microenvironment for therapeutic cancer treatment Review

Lysis-independent potentiation of immune checkpoint blockade by oncolytic virus Research Paper

PD-L1 is expressed on human platelets and is affected by immune checkpoint therapy Research Paper

Prognostic values of the mRNA expression of natural killer receptor ligands and their association with clinicopathological features in breast cancer patients Research Paper

Development of a preclinical humanized mouse model to evaluate acute toxicity of an influenza vaccine Research Paper

Development of a cell-based assay to identify hepatitis B virus entry inhibitors targeting the sodium taurocholate cotransporting polypeptide Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

The emerging role of human cytomegalovirus infection in human carcinogenesis: a review of current evidence and potential therapeutic implications Review

Differential microglia and macrophage profiles in human IDH-mutant and -wild type glioblastoma Research Paper

A novel anti-melanoma SRC-family kinase inhibitor Research Paper

FGF2-FGFR1 pathway activation together with thymidylate synthase upregulation is induced in pemetrexed-resistant lung cancer cells Research Paper

Immunonutritional consequences of different serine-type protease inhibitors in a C57BL/6 hepatocarcinoma model Research Paper

Genetically coating oncolytic herpes simplex virus with CD47 allows efficient systemic delivery and prolongs virus persistence at tumor site Research Paper

The double stranded RNA analog poly-IC elicits both robust IFN-Î» production and oncolytic activity in human gastrointestinal cancer cells Research Paper

Intestinal epithelial Notch-1 protects from colorectal mucinous adenocarcinoma Research Paper

Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy Review

Cell-specific plasticity associated with integrative memory of triple sensory signals in the barrel cortex Research Paper

The inhibition of malignant melanoma cell invasion of bone by the TLR7 agonist R848 is dependent upon pro-inflammatory cytokines produced by bone marrow macrophages Research Paper

Harnessing RIG-I and intrinsic immunity in the tumor microenvironment for therapeutic cancer treatment Review

Lysis-independent potentiation of immune checkpoint blockade by oncolytic virus Research Paper

PD-L1 is expressed on human platelets and is affected by immune checkpoint therapy Research Paper

Prognostic values of the mRNA expression of natural killer receptor ligands and their association with clinicopathological features in breast cancer patients Research Paper

Development of a preclinical humanized mouse model to evaluate acute toxicity of an influenza vaccine Research Paper

Development of a cell-based assay to identify hepatitis B virus entry inhibitors targeting the sodium taurocholate cotransporting polypeptide Research Paper