The Oncosearch | Oncotarget

mTOR inhibition as an adjuvant therapy in a metastatic model of HPV+ HNSCC Research Paper

Joseph D. Coppock, Paola D. Vermeer, Daniel W. Vermeer, Kimberly M. Lee, W. Keith Miskimins, William C. Spanos, John H. Lee

Published Mar 23, 2016 · Vol. 7, No. 17 · pp. 24228-24241

Advanced malignancies treated with a combination of the VEGF inhibitor bevacizumab, anti-EGFR antibody cetuximab, and the mTOR inhibitor temsirolimus Research Paper

Xiaochun Liu, Susan Kambrick, Siqing Fu, Aung Naing, Vivek Subbiah, George R. Blumenschein, Bonnie S. Glisson, Merrill S. Kies, Apostolia M. Tsimberidou, Jennifer J. Wheler, Ralph G. Zinner, David S. Hong, Razelle Kurzrock, Sarina A. Piha-Paul

Published Feb 24, 2016 · Vol. 7, No. 17 · pp. 23227-23238

Development of a metabolites risk score for one-year mortality risk prediction in pancreatic adenocarcinoma patients Research Paper

Andrea Fontana, Massimiliano Copetti, Iole Maria Di Gangi, Tommaso Mazza, Francesca Tavano, Domenica Gioffreda, Fulvio Mattivi, Angelo Andriulli, Urska Vrhovsek, Valerio Pazienza

Published Feb 1, 2016 · Vol. 7, No. 8 · pp. 8968-8978

Identifying anti-cancer drug response related genes using an integrative analysis of transcriptomic and genomic variations with cell line-based drug perturbations Research Paper

Yi Sun, Wei Zhang, Yunqin Chen, Qin Ma, Jia Wei, Qi Liu

Published Jan 25, 2016 · Vol. 7, No. 8 · pp. 9404-9419

The pepperâ€™s natural ingredient capsaicin induces autophagy blockage in prostate cancer cells Research Paper

Ãgata Ramos-Torres, Alicia Bort, Cecilia Morell, Nieves RodrÃguez-Henche, InÃ©s DÃaz-Laviada

Published Nov 27, 2015 · Vol. 7, No. 2 · pp. 1569-1583

Phase 1b study of lenvatinib (E7080) in combination with temozolomide for treatment of advanced melanoma Clinical Research Papers

David S. Hong, Razelle Kurzrock, Gerald S. Falchook, Corina Andresen, Jennifer Kwak, Min Ren, Lucy Xu, Goldy C. George, Kevin B. Kim, Ly M. Nguyen, James P. Oâ€™Brien, John Nemunaitis

Published Oct 15, 2015 · Vol. 6, No. 40 · pp. 43127-43134

Differential susceptibility to colorectal cancer due to naturally occurring gut microbiota Research Paper

Aaron C. Ericsson, Sadia Akter, Marina M. Hanson, Susheel B. Busi, Taybor W. Parker, Rebecca J. Schehr, Miriam A. Hankins, Carin E. Ahner, Justin W. Davis, Craig L. Franklin, James M. Amos-Landgraf, Elizabeth C. Bryda

Published Sep 10, 2015 · Vol. 6, No. 32 · pp. 33689-33704

Triple negative breast cancer: looking for the missing link between biology and treatments Research Perspective

Giuseppe Palma, Giuseppe Frasci, Andrea Chirico, Emanuela Esposito, Claudio Siani, Carmela Saturnino, Claudio Arra, Gennaro Ciliberto, Antonio Giordano, Massimiliano Dâ€™Aiuto

Published Aug 30, 2015 · Vol. 6, No. 29 · pp. 26560-26574

Transcriptional profiling of interleukin-2-primed human adipose derived mesenchymal stem cells revealed dramatic changes in stem cells response imposed by replicative senescence Research Paper

Ping Niu, Aibek Smagul, Lu Wang, Aiman Sadvakas, Ying Sha, Laura M. PÃ©rez, Aliya Nussupbekova, Aday Amirbekov, Akan A. Akanov, Beatriz G. GÃ¡lvez, I. King Jordan, Victoria V. Lunyak

Published Jul 14, 2015 · Vol. 6, No. 20 · pp. 17938-17957

A plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2 Research Paper

Ammara Abdullah, Sanam Sane, Kate A. Branick, Jessica L Freeling, Hongmin Wang, Dong Zhang, Khosrow Rezvani

Published Jul 11, 2015 · Vol. 6, No. 27 · pp. 23561-23581

An open-label, single-arm, phase I/II study of lower-dose decitabine based therapy in patients with advanced hepatocellular carcinoma Clinical Research Papers

Qian Mei, Meixia Chen, Xuechun Lu, Xiang Li, Feng Duan, Maoqiang Wang, Guangbin Luo, Weidong Han

Published Mar 29, 2015 · Vol. 6, No. 18 · pp. 16698-16711

Extracellular vesicles from bone marrow mesenchymal stem/stromal cells transport tumor regulatory microRNA, proteins, and metabolites Research Paper

Krishna C. Vallabhaneni, Patrice Penfornis, Santosh Dhule, Francois Guillonneau, Kristen V. Adams, Yin Yuan Mo, Rui Xu, Yiming Liu, Kounosuke Watabe, Mohan C. Vemuri, Radhika Pochampally

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4953-4967

Targeting hypoxia-inducible factor-1Î± (HIF-1Î±) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab Clinical Research Papers

Gerald S. Falchook, Jennifer J. Wheler, Aung Naing, Edward F. Jackson, Filip Janku, David Hong, Chaan S. Ng, Nizar M. Tannir, Kristie N. Lawhorn, Mei Huang, Laura S. Angelo, Deeksha Vishwamitra, Kenneth Hess, Adrienne N. Howard, Kristin L. Parkhurst, Hesham M. Amin, Razelle Kurzrock

Published Nov 8, 2014 · Vol. 5, No. 21 · pp. 10280-10292

Stromal TGF-Î² signaling induces AR activation in prostate cancer Research Paper

Feng Yang, Yizhen Chen, Tao Shen, Dan Guo, Olga Dakhova, Michael M. Ittmann, Chad J. Creighton, Yiqun Zhang, Truong D. Dang, David R. Rowley

Published Nov 6, 2014 · Vol. 5, No. 21 · pp. 10854-10869

Keywords: TGF-ï¢, AR, tumor microenvironment, prostate stroma, prostate cancer, co-culture.

Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience Clinical Research Papers

Ming-Mo Hou, Xiaochun Liu, Jennifer Wheler, Aung Naing, David Hong, Robert L. Coleman, Apostolia Tsimberidou, Filip Janku, Ralph Zinner, Karen Lu, Razelle Kurzrock, Siqing Fu

Published Oct 29, 2014 · Vol. 5, No. 22 · pp. 11168-11179

Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice Research Paper

Sandra Dupouy, Van Kien Doan, Zherui Wu, Najat Mourra, Olivier De Wever, FrÃ©dÃ©rique Penault Llorca, Anne Cayre, Amal Kouchkar, Anne Gompel, Patricia Forgez

Published Oct 3, 2014 · Vol. 5, No. 18 · pp. 8235-8251

Keywords: ancer growth and metastasis, neurotensin, EGFR, HER2, HER3, EGF like ligands.

Neurotensin (NTS) and its receptor (NTSR1) causes EGFR, HER2 and HER3 over-expression and their autocrine/paracrine activation in lung tumors, confirming responsiveness to erlotinib Research Paper

Mohamad Younes, Zherui Wu, Sandra Dupouy, Audrey Mansuet Lupo, Najat Mourra, Takashi Takahashi, Jean-Francois Flejou, Jean TrÃ©daniel, Jean FranÃ§ois RÃ©gnard, Diane Damotte, Marco Alifano, Patricia Forgez

Published Sep 26, 2014 · Vol. 5, No. 18 · pp. 8252-8269

Keywords: Cancer growth and metastasis, neurotensin, EGFR, HER2, HER3, EGF like ligands.

Protein kinase D1 attenuates tumorigenesis in colon cancer by modulating Î²-catenin/T cell factor activity Research Paper

Vasudha Sundram, Aditya Ganju, Joshua E. Hughes, Sheema Khan, Subhash C. Chauhan, Meena Jaggi

Published Aug 4, 2014 · Vol. 5, No. 16 · pp. 6867-6884

Microsatellite instability and ploidy status define three categories with distinctive prognostic impact in endometrioid endometrial cancer Research Paper

Cristina Bilbao-Sieyro, Raquel RamÃrez-Moreno, GermÃ¡n RodrÃguez-GonzÃ¡lez, Orlando FalcÃ³n, Laureano LeÃ³n, Santiago Torres, Leandro FernÃ¡ndez, Sergio Alonso, NicolÃ¡s DÃaz-Chico, Manuel Perucho, Juan Carlos DÃaz-Chico

Published Jul 8, 2014 · Vol. 5, No. 15 · pp. 6206-6217

Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands Review

Pradip De, Jennifer Carlson, Brian Leyland-Jones, Nandini Dey

Published Jun 22, 2014 · Vol. 5, No. 13 · pp. 4581-4602

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mTOR inhibition as an adjuvant therapy in a metastatic model of HPV+ HNSCC Research Paper

Advanced malignancies treated with a combination of the VEGF inhibitor bevacizumab, anti-EGFR antibody cetuximab, and the mTOR inhibitor temsirolimus Research Paper

Development of a metabolites risk score for one-year mortality risk prediction in pancreatic adenocarcinoma patients Research Paper

Identifying anti-cancer drug response related genes using an integrative analysis of transcriptomic and genomic variations with cell line-based drug perturbations Research Paper

The pepperâ€™s natural ingredient capsaicin induces autophagy blockage in prostate cancer cells Research Paper

Phase 1b study of lenvatinib (E7080) in combination with temozolomide for treatment of advanced melanoma Clinical Research Papers

Differential susceptibility to colorectal cancer due to naturally occurring gut microbiota Research Paper

Triple negative breast cancer: looking for the missing link between biology and treatments Research Perspective

Transcriptional profiling of interleukin-2-primed human adipose derived mesenchymal stem cells revealed dramatic changes in stem cells response imposed by replicative senescence Research Paper

A plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2 Research Paper

An open-label, single-arm, phase I/II study of lower-dose decitabine based therapy in patients with advanced hepatocellular carcinoma Clinical Research Papers

Extracellular vesicles from bone marrow mesenchymal stem/stromal cells transport tumor regulatory microRNA, proteins, and metabolites Research Paper

Targeting hypoxia-inducible factor-1Î± (HIF-1Î±) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab Clinical Research Papers

Stromal TGF-Î² signaling induces AR activation in prostate cancer Research Paper

Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience Clinical Research Papers

Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice Research Paper

Neurotensin (NTS) and its receptor (NTSR1) causes EGFR, HER2 and HER3 over-expression and their autocrine/paracrine activation in lung tumors, confirming responsiveness to erlotinib Research Paper

Protein kinase D1 attenuates tumorigenesis in colon cancer by modulating Î²-catenin/T cell factor activity Research Paper

Microsatellite instability and ploidy status define three categories with distinctive prognostic impact in endometrioid endometrial cancer Research Paper

Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

mTOR inhibition as an adjuvant therapy in a metastatic model of HPV+ HNSCC Research Paper

Advanced malignancies treated with a combination of the VEGF inhibitor bevacizumab, anti-EGFR antibody cetuximab, and the mTOR inhibitor temsirolimus Research Paper

Development of a metabolites risk score for one-year mortality risk prediction in pancreatic adenocarcinoma patients Research Paper

Identifying anti-cancer drug response related genes using an integrative analysis of transcriptomic and genomic variations with cell line-based drug perturbations Research Paper

The pepperâ€™s natural ingredient capsaicin induces autophagy blockage in prostate cancer cells Research Paper

Phase 1b study of lenvatinib (E7080) in combination with temozolomide for treatment of advanced melanoma Clinical Research Papers

Differential susceptibility to colorectal cancer due to naturally occurring gut microbiota Research Paper

Triple negative breast cancer: looking for the missing link between biology and treatments Research Perspective

Transcriptional profiling of interleukin-2-primed human adipose derived mesenchymal stem cells revealed dramatic changes in stem cells response imposed by replicative senescence Research Paper

A plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2 Research Paper

An open-label, single-arm, phase I/II study of lower-dose decitabine based therapy in patients with advanced hepatocellular carcinoma Clinical Research Papers

Extracellular vesicles from bone marrow mesenchymal stem/stromal cells transport tumor regulatory microRNA, proteins, and metabolites Research Paper

Targeting hypoxia-inducible factor-1Î± (HIF-1Î±) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab Clinical Research Papers

Stromal TGF-Î² signaling induces AR activation in prostate cancer Research Paper

Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience Clinical Research Papers

Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice Research Paper

Neurotensin (NTS) and its receptor (NTSR1) causes EGFR, HER2 and HER3 over-expression and their autocrine/paracrine activation in lung tumors, confirming responsiveness to erlotinib Research Paper

Protein kinase D1 attenuates tumorigenesis in colon cancer by modulating Î²-catenin/T cell factor activity Research Paper

Microsatellite instability and ploidy status define three categories with distinctive prognostic impact in endometrioid endometrial cancer Research Paper

Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands Review