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427 results found — showing 1–20

Correction: Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism Correction

Claudia Fumarola, Daniele Cretella, Silvia La Monica, Mara A. Bonelli, Roberta Alfieri, Cristina Caffarra, Federico Quaini, Denise Madeddu, Angela Falco, Andrea Cavazzoni, Graziana Digiacomo, Giulia Mazzaschi, Valentina Vivo, Elisabetta Barocelli, Marcello Tiseo, Pier Giorgio Petronini, Andrea Ardizzoni
Published Mar 30, 2026 · Vol. 17, No. 1 · pp. 76-77

CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer Research Paper

Allison Makovec, John T. Phoenix, Hannah E. Bergom, Ella Boytim, Ava P. Gustafson, Aiden Deacon, Sydney Tape, Atef Ali, Megan Ludwig, Samuel P. Pitzen, David Moline, Camden Richter, Hudson Longie, Mei-Chi Su, Sampreeti Jena, Pornlada Likasitwatanakul, Justin M. Drake, R. Stephanie Huang, William C. Hahn, Jonathan P. Rennhack, Scott M. Dehm, Steven Kregel, Emmanuel S. Antonarakis, Justin Hwang
Published Mar 30, 2026 · Vol. 17, No. 1 · pp. 59-73
Keywords: prostate cancer, CREB5, basal-like, stem cell-like, AP-1 transcription factors

ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response Research Paper

Kyle R. Cron, Ping Fang, Oanh Pham, Julie Janes, John Brandenburg, William Lu, Jonathan Zhu, Bret Peterson, Sara Tribble, Haixing Kehoe, Anastasia Makarova, Alex Iannello, Jean Chan, Justin Skoble, Hailey He, Chris Rae, Christopher D. Thanos, Akshata R. Udyavar
Published Oct 2, 2025 · Vol. 16, No. 1 · pp. 721-740
Keywords: tumor microenvironment, bacterial vector, myeloid cells, STING, IL-15

Worldwide Innovative Network (WIN) Consortium in Personalized Cancer Medicine: Bringing next-generation precision oncology to patients Precision Oncology

Wafik S. El-Deiry, Catherine Bresson, Fanny Wunder, Benedito A. Carneiro, Don S. Dizon, Jeremy L. Warner, Stephanie L. Graff, Christopher G. Azzoli, Eric T. Wong, Liang Cheng, Sendurai A. Mani, Howard P. Safran, Casey Williams, Tobias Meissner, Benjamin Solomon, Eitan Rubin, Angel Porgador, Guy Berchem, Pierre Saintigny, Amir Onn, Jair Bar, Raanan Berger, Manon Gantenbein, Zhen Chen, Cristiano de Pádua Souza, Rui Manuel Vieira Reis, Marina Sekacheva, Andrés Cervantes, William L. Dahut, Christina M. Annunziata, Kerri Gober, Khaled M. Musallam, Humaid O. Al-Shamsi, Ibrahim Abu-Gheida, Ramon Salazar, Sewanti Limaye, Adel T. Aref, Roger R. Reddel, Mohammed Ussama Al Homsi, Abdul Rouf, Said Dermime, Jassim Al Suwaidi, Catalin Vlad, Rares Buiga, Amal Al Omari, Hikmat Abdel-Razeq, Luis F. Oñate-Ocaña, Finn Cilius Nielsen, Leah Graham, Jens Rueter, Anthony M. Joshua, Eugenia Girda, Steven Libutti, Gregory Riedlinger, Mohammed E. Salem, Carol J. Farhangfar, Ruben A. Mesa, Bishoy M. Faltas, Olivier Elemento, C.S. Pramesh, Manju Sengar, Satoru Aoyama, Sadakatsu Ikeda, Ioana Berindan-Neagoe, Himabindu Gaddipati, Mandar Kulkarni, Elisabeth Auzias, Maria Gerogianni, Nicolas Wolikow, Simon Istolainen, Pessie Schlafrig, Naftali Z. Frankel, Amanda R. Ferraro, Jim Palma, Alejandro Piris Gimenez, Alberto Hernando-Calvo, Enriqueta Felip, Apostolia M. Tsimberidou, Roy S. Herbst, Josep Tabernero, Richard L. Schilsky, Jia Liu, Yves Lussier, Jacques Raynaud, Gerald Batist, Shai Magidi, Razelle Kurzrock
Published Mar 12, 2025 · Vol. 16, No. 1 · pp. 140-162
Keywords: precision oncology, N-of-1 basket trials, AI algorithms, digital pathology, drug access

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

Chantal L. Duurland, Thijs de Gunst, Harm C. den Boer, Marion T.J. van den Bosch, Bryony J. Telford, Rogier M. Vos, Xiaolei Xie, Mingfa Zang, Fang Wang, Yingying Shao, Xiaoyu An, Jingjing Wang, Jie Cai, Ludovic Bourré, Laurens A.H. van Pinxteren, Roel Q.J. Schaapveld, Michel Janicot, Sanaz Yahyanejad
Published Jul 4, 2024 · Vol. 15, No. 1 · pp. 470-485
Keywords: miR-193a-3p, microRNA mimic, T cell mediated immunity, immunogenic cell death, cancer

Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma Research Paper

Kazuhiro Kitajima, Kozo Kuribayashi, Toshiyuki Minami, Hiroyuki Yokoyama, Akifumi Nakamura, Masaki Hashimoto, Takashi Kijima, Seiki Hasegawa, Hayato Kaida, Koichiro Yamakado
Published Jun 11, 2024 · Vol. 15, No. 1 · pp. 408-417
Keywords: mesothelioma, immunotherapy, FDG (fluorodeoxyglucose), PET-CT (positron emission tomography-computed tomography), immunotherapy-modified PERCIST (positron emission tomography response criteria in solid tumors)

GZ17-6.02 kills PDX isolates of uveal melanoma Research Paper

Laurence Booth, Jane L. Roberts, Ivan Spasojevic, Kaitlyn C. Baker, Andrew Poklepovic, Cameron West, John M. Kirkwood, Paul Dent
Published May 9, 2024 · Vol. 15, No. 1 · pp. 328-344
Keywords: autophagy, ER stress, GZ17-6.02, doxorubicin, afatinib, neratinib
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