Oncotarget

Corrections:

Correction: Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer

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Oncotarget. 2024; 15:504-506. https://doi.org/10.18632/oncotarget.28527

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Yiyao Zhang1,2,3,4, Li Liu1,2,3, Pei Fan1,2,3, Nathalie Bauer1,2,3, Jury Gladkich1,2,3, Eduard Ryschich2,3, Alexandr V. Bazhin3, Nathalia A. Giese3, Oliver Strobel3, Thilo Hackert3, Ulf Hinz3, Wolfgang Gross1,2,3, Franco Fortunato2,3 and Ingrid Herr1,2,3

1Molecular OncoSurgery, University of Heidelberg and German Cancer Research Center (DKFZ), Heidelberg, Germany
2Section Surgical Research, University of Heidelberg, Heidelberg, Germany
3Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany
4Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University, Xiamen, China

Published: July 17, 2024

Copyright: © 2024 Zhang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

This article has been corrected: In Figure 7, images for the control groups were accidentally inserted into the ASA, GEM, and A+G rows, instead of those from the treatment groups. In addition, in Supplementary Figure 3, panel T22, the images for samples act. Casp3 and c-Met are accidental duplicates. The corrected Figure 7 and Supplementary Figure 3, produced using the original data, are shown below. The authors declare that these corrections do not change the results or conclusions of this paper.

Original article: Oncotarget. 2015; 6:9999–10015. DOI: https://doi.org/10.18632/oncotarget.3171

Figure 7: Aspirin intake before surgery inhibits the expression of progression markers in PDA patient tissue. Tumor tissue sections derived from patients with documented pre-operative administration of aspirin (n = 7), gemcitabine (n = 5), aspirin plus gemcitabine (n = 3), or neither aspirin nor gemcitabine (n = 6) were evaluated by immunohistochemistry for the expression of the proliferation marker Ki67, the inflammatory factor TNF-α, and the CSC markers c-Met, CD44 and CXCR4. The scale bar indicates 50 μm. The number of positive cells was quantified in 10 visual fields at 400× magnification, and the means ± SD are shown in the diagrams. The data are presented as means ± SD (**P < 0.01, *P < 0.05).

Supplementary Figure 3: Aspirin inhibits the expression of progression markers in primary CSCs spheroids and enhances gemcitabine efficacy. Immunohistochemical staining is shown for primary spheroids, which were obtained and treated as described in Figure 4.


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