A low psoas muscle volume is associated with a poor prognosis in penile cancer

Daiji Takkamoto; Takashi Kawahara; Takashi Tokita; Jun Kasuga; Yasushi Yumura; Hiroji Uemura

doi:10.18632/oncotarget.27719

Oncotarget

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. The term was introduced in the inaugural Editorial, Introducing Oncotarget.

As of January 1, 2022, Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Subscribe to receive alerts once a paper has been published by Oncotarget.

Learn about our FREE

Post-Publication Promotion Services

50% on all publication fees until the end of 2024.

Impact Journals, LLC is the publisher of Oncotarget: www.impactjournals.com.

Impact Journals is a member of the Wellcome Trust List of Compliant Publishers.

Impact Journals is a member of the Society for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control. This malicious action will be reported to the FBI.

Research Papers:

A low psoas muscle volume is associated with a poor prognosis in penile cancer

Daiji Takkamoto, Takashi Kawahara _, Takashi Tokita, Jun Kasuga, Yasushi Yumura and Hiroji Uemura

PDF | Full Text | Supplementary Files | How to cite

Oncotarget. 2020; 11:3526-3530. https://doi.org/10.18632/oncotarget.27719

Metrics: PDF 1001 views | Full Text 1438 views | ?

Abstract

Daiji Takkamoto1, Takashi Kawahara1, Takashi Tokita2, Jun Kasuga1, Yasushi Yumura1 and Hiroji Uemura1

1 Department of Urology and Renal Transportation, Yokohama City University Medical Center, Yokohama, Japan

2 Department of Urology, Toshiba Rinkan Hospital, Sagamihara, Japan

Correspondence to:

Takashi Kawahara,

email:

[email protected]

Keywords: sarcopenia; penile cancer; psoas muscle; psoas muscle volume; penectomy

Received: July 22, 2020 Accepted: August 11, 2020 Published: September 22, 2020

ABSTRACT

Background: Sarcopenia was initially recognized as a marker representing the nutritional condition or aging. Recently, sarcopenia has been associated with a poor prognosis and postoperative complications. We examined the importance of sarcopenia as a predictive marker of the prognosis in penile cancer.

Materials and Methods: A total of 25 patients diagnosed with penile cancer who underwent penile resection from 2000 to 2010 were analyzed in this study. The psoas muscle index (PMI) was calculated based on psoas area using preoperative axial computed tomography images at the right L3 level divided by the square of the body height.

Results: Nineteen (76.0%) patients underwent partial penectomy, and 6 (24.0%) underwent total penectomy. The median (mean ± standard deviation) age was 69.3 (69.0 ± 10.1) years old. Regarding the site of penile cancer, 17 (76.0%) cases were in the glans, 6 (24.0%) were in the foreskin, and 2 (8.0%) were in the shaft. Lymph node metastasis were seen in 6 cases (24.0%), and distant metastasis was seen in 1 case (4.0%). The lower PMI group (< 320.0) showed a significantly poorer progression-free survival than the higher PMI group (≥ 320.0) (p = 0.030), although no significant difference in the overall survival was noted (p = 0.076).

Conclusions: Sarcopenia might be a useful prognostic factor in penile cancer patients.

All site content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 License.
PII: 27719

Publication Alerts

Post-Publication Promotion

Publication Discount

Research Papers:

A low psoas muscle volume is associated with a poor prognosis in penile cancer

Abstract