Oncotarget

Meta-Analysis:

Difference in the prevalence of non-fatal suicidal behaviours in patients with unipolar and bipolar depression in China: a meta-analysis

Peiwei Shan _, Liuzhen Hu, Dali Xu, Chunxia Fang, Jie Li, Deguo Jiang, Wei Zhang and Chuanjun Zhuo

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Oncotarget. 2018; 9:35493-35499. https://doi.org/10.18632/oncotarget.24554

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Abstract

Peiwei Shan1,*, Liuzhen Hu2,*, Dali Xu1,*, Chunxia Fang1, Jie Li2, Deguo Jiang1,#, Wei Zhang1,# and Chuanjun Zhuo1,3,#

1The Department of Psychiatry, Wenzhou Seventh People’s Hospital, Wenzhou City, 325000, Zhejiang Province, China

2The Department of Psychiatry, Changzhou Dean Hospital, Changzhou City, 213000, Jiangsu Province, China

3The Department of Psychiatry, Tianjin Anding Hospital, Tianjin Mental Health Center, Tianjin City, 300222, China

*These authors contributed equally to this work

#These authors are considered as the co-corresponding authors

Correspondence to:

Chuanjun Zhuo, email: [email protected]

Deguo Jiang, email: [email protected]

Wei Zhang, email: [email protected]

Keywords: unipolar depression; bipolar depression; non-fatal suicidal behaviours

Received: September 01, 2017     Accepted: October 29, 2017     Epub: February 22, 2018     Published: October 26, 2018

ABSTRACT

Difference in the prevalence of non-fatal suicidal behaviours in patients with unipolar and bipolar depression in China is rarely reported. We conducted a meta-analysis to examine this difference. Major Chinese and English literature databases were searched online to collect studies comparing the prevalence of non-fatal suicidal behaviours of patients with unipolar and bipolar depression. The quality of the included studies was assessed according to the matching principle. Risk difference (RD) of prevalence rates of non-fatal suicidal behaviours between patients with unipolar and bipolar depression was calculated. A total of 16 studies, containing 1678 cases with unipolar depression and 1069 cases with bipolar depression, were included. Differences in rates of suicidal ideation and attempt were not statistically significant between patients with unipolar and bipolar depression, but rates of overall non-fatal suicidal behaviours in patients with unipolar depression was significantly higher than those with bipolar depression (RD: 0.28, 95% CI: 0.20, 0.36). In summary, the rate of overall non-fatal suicidal behaviours of patients with unipolar depression is higher than that of patients with bipolar depression in China.


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