Experimental study of brachial plexus and vessel compression: evaluation of combined central and peripheral electrodiagnostic approach

Chaoqun Yang; Jianguang Xu; Jie Chen; Shulin Li; Yu Cao; Yi Zhu; Lei Xu

doi:10.18632/oncotarget.16817

Oncotarget

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. The term was introduced in the inaugural Editorial, Introducing Oncotarget.

As of January 1, 2022, Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Subscribe to receive alerts once a paper has been published by Oncotarget.

Learn about our FREE

Post-Publication Promotion Services

50% on all publication fees until the end of 2024.

Impact Journals, LLC is the publisher of Oncotarget: www.impactjournals.com.

Impact Journals is a member of the Wellcome Trust List of Compliant Publishers.

Impact Journals is a member of the Society for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control. This malicious action will be reported to the FBI.

Research Papers:

Experimental study of brachial plexus and vessel compression: evaluation of combined central and peripheral electrodiagnostic approach

Chaoqun Yang, Jianguang Xu, Jie Chen, Shulin Li, Yu Cao, Yi Zhu and Lei Xu _

PDF | HTML | How to cite

Oncotarget. 2017; 8:50618-50628. https://doi.org/10.18632/oncotarget.16817

Metrics: PDF 1469 views | HTML 2105 views | ?

Abstract

Chaoqun Yang1, Jianguang Xu1, Jie Chen1, Shulin Li1, Yu Cao1, Yi Zhu1 and Lei Xu1

1Department of Hand Surgery, Huashan Hospital, Fudan University, Shanghai, China

Correspondence to:

Lei Xu, email: [email protected]

Keywords: brachial plexus, electrodiagnosis, electrophysiology, experimental study

Received: January 23, 2017 Accepted: March 09, 2017 Published: April 04, 2017

ABSTRACT

Introduction: We sought to investigate the reliability of a new electrodiagnostic method for identifying Electrodiagnosis of Brachial Plexus & Vessel Compression Syndrome (BPVCS) in rats that involves the application of transcranial electrical stimulation motor evoked potentials (TES-MEPs) combined with peripheral nerve stimulation compound muscle action potentials (PNS-CMAPs).

Results: The latencies of the TES-MEP and PNS-CMAP were initially elongated in the 8-week group. The amplitudes of TES-MEP and PNS-CMAP were initially attenuated in the 16-week group. The isolateral amplitude ratio of the TES-MEP to the PNS-CMAP was apparently decreased, and spontaneous activities emerged at 16 weeks postoperatively.

Materials and Methods: Superior and inferior trunk models of BPVCS were created in 72 male Sprague Dawley (SD) rats that were divided into six experimental groups. The latencies, amplitudes and isolateral amplitude ratios of the TES-MEPs and PNS-CMAPs were recorded at different postoperative intervals.

Conclusions: Electrophysiological and histological examinations of the rats’ compressed brachial plexus nerves were utilized to establish preliminary electrodiagnostic criteria for BPVCS.

All site content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 License.
PII: 16817

Publication Alerts

Post-Publication Promotion

Publication Discount

Research Papers:

Experimental study of brachial plexus and vessel compression: evaluation of combined central and peripheral electrodiagnostic approach

Abstract