Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature

Qinjie Weng; Xiao Li; Hong Ren; Jingyuan Xie; Xiaoxia Pan; Jing Xu; Nan Chen

doi:10.18632/oncotarget.15397

Oncotarget

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. The term was introduced in the inaugural Editorial, Introducing Oncotarget.

As of January 1, 2022, Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Subscribe to receive alerts once a paper has been published by Oncotarget.

Learn about our FREE

Post-Publication Promotion Services

Impact Journals, LLC is the publisher of Oncotarget: www.impactjournals.com.

Impact Journals is a member of the Wellcome Trust List of Compliant Publishers.

Impact Journals is a member of the Society for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control. This malicious action will be reported to the FBI.

Case Reports:

Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature

Qinjie Weng _, Xiao Li, Hong Ren, Jingyuan Xie, Xiaoxia Pan, Jing Xu and Nan Chen

PDF | HTML | How to cite

Oncotarget. 2017; 8:22299-22303. https://doi.org/10.18632/oncotarget.15397

Metrics: PDF 2439 views | HTML 2523 views | ?

Abstract

Qinjie Weng1, Xiao Li1, Hong Ren1, Jingyuan Xie1, Xiaoxia Pan1, Jing Xu1 and Nan Chen1

1 Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

Correspondence to:

Nan Chen, email:

Keywords: hepatitis C virus, membranous nephropathy, hepatitis C virus-related glomerulonephritis, Ledipasvir-Sofosbuvir, case report

Received: October 02, 2016 Accepted: January 25, 2017 Published: February 16, 2017

Abstract

Background: Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults. As many clinical cases have reported, it may be associated with hepatitis C virus (HCV) infection. Antiviral therapy can be various.

Case summary: We report a case of patient with chronic HCV infection and MN, who presented with was proteinuria. He was treated with ledipasvir and sofosbuvir (Harvoni; Gilead Sciences, Foster City, CA) and was found to be virus-free.

Conclusion: We have reported this case to provide insight into whether Ledipasvir-Sofosbuvir should be administered for HCV-related glomerulonephritis.

All site content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 License.
PII: 15397

Publication Alerts

Post-Publication Promotion

Case Reports:

Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature

Abstract