Clinical significance of circulating tumor cells in gastric cancer patients

Jitao Zhou; Xin Ma; Feng Bi; Ming Liu

doi:10.18632/oncotarget.14879

Oncotarget

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. The term was introduced in the inaugural Editorial, Introducing Oncotarget.

As of January 1, 2022, Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Subscribe to receive alerts once a paper has been published by Oncotarget.

Learn about our FREE

Post-Publication Promotion Services

50% on all publication fees until the end of 2024.

Impact Journals, LLC is the publisher of Oncotarget: www.impactjournals.com.

Impact Journals is a member of the Wellcome Trust List of Compliant Publishers.

Impact Journals is a member of the Society for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control. This malicious action will be reported to the FBI.

Reviews:

Clinical significance of circulating tumor cells in gastric cancer patients

Jitao Zhou, Xin Ma, Feng Bi and Ming Liu _

PDF | HTML | How to cite

Oncotarget. 2017; 8:25713-25720. https://doi.org/10.18632/oncotarget.14879

Metrics: PDF 5027 views | HTML 5919 views | ?

Abstract

Jitao Zhou1,*, Xin Ma1,*, Feng Bi1 and Ming Liu1

1 Department of Medical Oncology/Laboratory of Signal Transduction & Molecular Targeted Therapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China

* These authors have contributed equally to this work

Correspondence to:

Ming Liu, email:

Keywords: CTC; gastric cancer; EMT; Cellsearch; cancer metastasis

Received: August 29, 2016 Accepted: January 16, 2017 Published: January 28, 2017

Abstract

Circulating tumor cells (CTCs) are rare cancer cells released from tumors into the blood stream that are thought to have a key role in cancer metastasis. Investigation of CTCs is an exciting area of research but remains in its infancy, and the presence of CTCs has been associated with worse prognosis in several major cancer types. Gastric cancer (GC) is a highly lethal malignancy and a serious public health concern in East Asia especially in China. There is an urgent need for identifying new, better prognostic markers to enhance diagnosis and prognosis, facilitate drug development, and to improve the treatment of gastric cancer patients. There are considerable interests in gastric CTCs given their potential use as gastric cancer biomarkers. This review highlights recent advances in studies of gastric CTCs, including the isolation and biological molecular characteristics of gastric CTCs, and their clinical significance.

All site content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 License.
PII: 14879

Publication Alerts

Post-Publication Promotion

Publication Discount

Reviews:

Clinical significance of circulating tumor cells in gastric cancer patients

Abstract