Oncotarget

Clinical Research Papers:

Factors that influence treatment delay in patients with colorectal cancer

Irene Zarcos-Pedrinaci _, Alberto Fernández-López, Teresa Téllez, Francisco Rivas-Ruiz, Antonio Rueda A, María Manuela Morales Suarez-Varela, Eduardo Briones, Marisa Baré, Antonio Escobar, Cristina Sarasqueta, Nerea Fernández de Larrea, Urko Aguirre, José María Quintana, Maximino Redondo and on behalf of the CARESS-CCR Study Group

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Oncotarget. 2017; 8:36728-36742. https://doi.org/10.18632/oncotarget.13574

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Abstract

Irene Zarcos-Pedrinaci1,11, Alberto Fernández-López2, Teresa Téllez1,11, Francisco Rivas-Ruiz1,11, Antonio Rueda A3,11, María Manuela Morales Suarez-Varela4, Eduardo Briones5, Marisa Baré6,11, Antonio Escobar7,11, Cristina Sarasqueta8,11, Nerea Fernández de Larrea9,11, Urko Aguirre10,11, José María Quintana10,11, Maximino Redondo1,11 and On Behalf of the CARESS-CCR Study Group

1Research Unit, Agencia Sanitaria Costa del Sol, Marbella, Spain

2Servicio de Cirugía, Agencia Sanitaria Costa del Sol, Marbella, Spain

3Servicio de Oncología Médica, Agencia Sanitaria Costa del Sol, Marbella, Spain

4Unit of Public Health, Hygiene and Environmental Health, Department of Preventive Medicine and Public Health, Food Science, Toxicology and Legal Medicine, University of Valencia, CIBER-Epidemiology and Public Health (CIBERESP), Valencia, Spain

5Public Health Unit, Distrito Sanitario Sevilla, Consorcio de Investigación Biomédica de Epidemiología y Salud Pública, Madrid, Spain

6Clinical Epidemiology and Cancer Screening, Corporació Sanitària Parc Taulí, Sabadell, Spain

7Research Unit, Hospital Universitario Basurto, Bilbao, Spain

8Research Unit, Donostia University Hospital, San Sebastián, Spain

9Area of Environmental Epidemiology and Cancer, National Epidemiology Centre, Instituto de Salud Carlos III, Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública, CIBERESP), Madrid, Spain

10Research Unit, Hospital Galdakao-Usansolo, Galdakao, Spain

11Red de Investigación en Servicios de Salud en Enfermedades Crónicas – REDISSEC, Spain

Correspondence to:

Maximino Redondo, email: [email protected]

Keywords: colorectal, cancer, delay, treatment, education

Received: May 30, 2016    Accepted: November 12, 2016    Published: November 24, 2016

ABSTRACT

A prospective study was performed of patients diagnosed with colorectal cancer (CRC), distinguishing between colonic and rectal location, to determine the factors that may provoke a delay in the first treatment (DFT) provided.

2749 patients diagnosed with CRC were studied. The study population was recruited between June 2010 and December 2012. DFT is defined as time elapsed between diagnosis and first treatment exceeding 30 days.

Excessive treatment delay was recorded in 65.5% of the cases, and was more prevalent among rectal cancer patients. Independent predictor variables of DFT in colon cancer patients were a low level of education, small tumour, ex-smoker, asymptomatic at diagnosis and following the application of screening. Among rectal cancer patients, the corresponding factors were primary school education and being asymptomatic.

We conclude that treatment delay in CRC patients is affected not only by clinicopathological factors, but also by sociocultural ones. Greater attention should be paid by the healthcare provider to social groups with less formal education, in order to optimise treatment attention.


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