Oncotarget

December 14, 2018

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About The Cover

The cover for issue 98 of Oncotarget features Figure 7, "A working model: The payload (DM1)-mediated cytotoxicity," by Endo, et al.

Table of Contents

Editorial

No equal opportunity for leukemia initiating cells

No equal opportunity for leukemia initiating cells

https://doi.org/10.18632/oncotarget.26454

Tom Verbiest, Simon Bouffler,  and Christophe Badie
37078-37079
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Research Papers

A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models

A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models

https://doi.org/10.18632/oncotarget.26354

Kaiming Sun, Keith Mikule, Zebin Wang, Grace Poon, Aparajitha Vaidyanathan, Gillian Smith, Zhi-Yi Zhang, Jeffrey Hanke, Sridhar Ramaswamy,  and Jing Wang
37080-37096
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Oncogenic transgelin-2 is differentially regulated in isocitrate dehydrogenase wild-type vs. mutant gliomas

Oncogenic transgelin-2 is differentially regulated in isocitrate dehydrogenase wild-type vs. mutant gliomas

https://doi.org/10.18632/oncotarget.26365

Sasha J. Beyer, Erica H. Bell, Joseph P. McElroy, Jessica L. Fleming, Tiantian Cui, Aline Becker, Emily Bassett, Benjamin Johnson, Pooja Gulati, Ilinca Popp, Ori Staszewski, Marco Prinz, Anca L. Grosu, Saikh Jaharul Haque,  and Arnab Chakravarti
37097-37111
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Detection of histone H3 K27M mutation and post-translational modifications in pediatric diffuse midline glioma via tissue immunohistochemistry informs diagnosis and clinical outcomes

Detection of histone H3 K27M mutation and post-translational modifications in pediatric diffuse midline glioma via tissue immunohistochemistry informs diagnosis and clinical outcomes

https://doi.org/10.18632/oncotarget.26430

Tina Huang, Roxanna Garcia, Jin Qi, Rishi Lulla, Craig Horbinski, Amir Behdad, Nitin Wadhwani, Ali Shilatifard, Charles James,  and Amanda M. Saratsis
37112-37124
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Predicting clinically significant prostate cancer using DCE-MRI habitat descriptors

Predicting clinically significant prostate cancer using DCE-MRI habitat descriptors

https://doi.org/10.18632/oncotarget.26437

N. Andres Parra, Hong Lu, Qian Li, Radka Stoyanova, Alan Pollack, Sanoj Punnen, Jung Choi, Mahmoud Abdalah, Christopher Lopez, Kenneth Gage, Jong Y. Park, Yamoah Kosj, Julio M. Pow-Sang, Robert J. Gillies,  and Yoganand Balagurunathan
37125-37136
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

The molecular mechanism of action of methylene quinuclidinone and its effects on the structure of p53 mutants

The molecular mechanism of action of methylene quinuclidinone and its effects on the structure of p53 mutants

https://doi.org/10.18632/oncotarget.26440

Sara Ibrahim Omar,  and Jack Tuszynski
37137-37156
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

STAT1 deficiency supports PD-1/PD-L1 signaling resulting in dysfunctional TNFα mediated immune responses in a model of NSCLC

STAT1 deficiency supports PD-1/PD-L1 signaling resulting in dysfunctional TNFα mediated immune responses in a model of NSCLC

https://doi.org/10.18632/oncotarget.26441

Juliane Friedrich, Lisanne Heim, Denis I. Trufa, Horia Sirbu, Ralf J. Rieker, Mircea T. Chiriac,  and Susetta Finotto
37157-37172
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Chronic lymphocytic leukemia cells from ibrutinib treated patients are sensitive to Axl receptor tyrosine kinase inhibitor therapy

Chronic lymphocytic leukemia cells from ibrutinib treated patients are sensitive to Axl receptor tyrosine kinase inhibitor therapy

https://doi.org/10.18632/oncotarget.26444

Sutapa Sinha, Justin C. Boysen, Kari G. Chaffee, Brian F. Kabat, Susan L. Slager, Sameer A. Parikh, Charla R. Secreto, Tim Call, Tait D. Shanafelt, Jose F. Leis, Steven L. Warner, David J. Bearss, Asish K. Ghosh,  and Neil E. Kay
37173-37184
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Microenvironment-derived ADAM28 prevents cancer dissemination

Microenvironment-derived ADAM28 prevents cancer dissemination

https://doi.org/10.18632/oncotarget.26449

Catherine Gérard, Céline Hubeau, Oriane Carnet, Marine Bellefroid, Nor Eddine Sounni, Silvia Blacher, Guillaume Bendavid, Markus Moser, Reinhard Fässler, Agnès Noel, Didier Cataldo,  and Natacha Rocks
37185-37199
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Payload of T-DM1 binds to cell surface cytoskeleton-associated protein 5 to mediate cytotoxicity of hepatocytes

Payload of T-DM1 binds to cell surface cytoskeleton-associated protein 5 to mediate cytotoxicity of hepatocytes

https://doi.org/10.18632/oncotarget.26461

Yukinori Endo, Kazuyo Takeda, Nishant Mohan, Yi Shen, Jiangsong Jiang, David Rotstein,  and Wen Jin Wu
37200-37215
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite  |  Press Release

Y-box binding protein YBX1 and its correlated genes as biomarkers for poor outcomes in patients with breast cancer

Y-box binding protein YBX1 and its correlated genes as biomarkers for poor outcomes in patients with breast cancer

https://doi.org/10.18632/oncotarget.26469

Tomohiro Shibata, Eriko Tokunaga, Satoshi Hattori, Kosuke Watari, Yuichi Murakami, Nami Yamashita, Eiji Oki, Junji Itou, Masakazu Toi, Yoshihiko Maehara, Michihiko Kuwano,  and Mayumi Ono
37216-37228
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Reviews

Extracellular vesicles: biomarkers and regulators of vascular function during extracorporeal circulation

Extracellular vesicles: biomarkers and regulators of vascular function during extracorporeal circulation

https://doi.org/10.18632/oncotarget.26433

Mark J. McVey,  and Wolfgang M. Kuebler
37229-37251
Abstract  |  PDF  |  HTML  |  How to cite

Cell penetrating peptides in preclinical and clinical cancer diagnosis and therapy

Cell penetrating peptides in preclinical and clinical cancer diagnosis and therapy

https://doi.org/10.18632/oncotarget.26442

Prem Prakash Tripathi, Hamed Arami, Ivneet Banga, Jalaj Gupta,  and Sonu Gandhi
37252-37267
Abstract  |  PDF  |  HTML  |  How to cite

Corrections

Correction: Verteporfin inhibits gastric cancer cell growth by suppressing adhesion molecule FAT1

Correction: Verteporfin inhibits gastric cancer cell growth by suppressing adhesion molecule FAT1

https://doi.org/10.18632/oncotarget.26488

Myoung-Hee Kang, Gi Seok Jeong, Duane T. Smoot, Hassan Ashktorab, Chang Mo Hwang, Byung Sik Kim, Hee Sung Kim,  and Yun-Yong Park
37268-37268
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Correction: Oncogenomics of c-Myc transgenic mice reveal novel regulators of extracellular signaling, angiogenesis and invasion with clinical significance for human lung adenocarcinoma

Correction: Oncogenomics of c-Myc transgenic mice reveal novel regulators of extracellular signaling, angiogenesis and invasion with clinical significance for human lung adenocarcinoma

https://doi.org/10.18632/oncotarget.26489

Yari Ciribilli,  and Jürgen Borlak
37269-37269
Correction  |  PDF  |  How to cite


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