Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-β receptor type I inhibitor
Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-β receptor type I inhibitor |
https://doi.org/10.18632/oncotarget.23795
Jonathan M. Yingling,
William T. McMillen,
Lei Yan,
Huocong Huang,
J. Scott Sawyer,
Jeremy Graff,
David K. Clawson,
Karen S. Britt,
Bryan D. Anderson,
Douglas W. Beight,
Durisala Desaiah,
Michael M. Lahn,
Karim A. Benhadji,
Maria J. Lallena,
Rikke B. Holmgaard,
Xiaohong Xu,
Faming Zhang,
Jason R. Manro,
Philip W. Iversen,
Chandrasekar V. Iyer,
Rolf A. Brekken,
Michael D. Kalos,
and Kyla E. Driscoll
|
6659-6677 |
Interleukin-13 peptide vaccine induces protective humoral immunity in murine asthma models
Interleukin-13 peptide vaccine induces protective humoral immunity in murine asthma models |
https://doi.org/10.18632/oncotarget.19950
Fengbo Wu,
Yan Huang,
Peng Zhang,
Chunting Wang,
Yaomei Tian,
Lian Lu,
Gu He,
and Li Yang
|
6678-6690 |
Idiopathic multicentric Castleman’s disease: a clinicopathologic study in comparison with IgG4-related disease
Idiopathic multicentric Castleman’s disease: a clinicopathologic study in comparison with IgG4-related disease |
https://doi.org/10.18632/oncotarget.24068
Kyoko Otani,
Dai Inoue,
Kohei Fujikura,
Takahiro Komori,
Shiho Abe-Suzuki,
Takuma Tajiri,
Tomoo Itoh,
and Yoh Zen
|
6691-6706 |
Endoplasmic reticulum stress stimulates the release of extracellular vesicles carrying danger-associated molecular pattern (DAMP) molecules
Endoplasmic reticulum stress stimulates the release of extracellular vesicles carrying danger-associated molecular pattern (DAMP) molecules |
https://doi.org/10.18632/oncotarget.24158
Gavin P. Collett,
Christopher W. Redman,
Ian L. Sargent,
and Manu Vatish
|
6707-6717 |
Type 2 diabetes epidemic in East Asia: a 35–year systematic trend analysis
Type 2 diabetes epidemic in East Asia: a 35–year systematic trend analysis |
https://doi.org/10.18632/oncotarget.22961
Huiping Yuan,
Xinghui Li,
Gang Wan,
Liang Sun,
Xiaoquan Zhu,
Fugang Che,
and Ze Yang
|
6718-6727 |
Synthetic analysis of associations between IL-10 polymorphisms and skin cancer risk
Synthetic analysis of associations between IL-10 polymorphisms and skin cancer risk |
https://doi.org/10.18632/oncotarget.23385
Hongbo Zhao,
Jiaoli Yang,
Zhenzhen Yu,
Hui Shen,
Xinlin Huang,
Mi Zhang,
Teng Long,
Cailing A,
and Wenhui Wang
|
6728-6736 |
Prognostic significance of Cytokeratin 20-positive lymph node vascular endothelial growth factor A mRNA and chromodomain helicase DNA binding protein 4 in pN0 colorectal cancer patients
Prognostic significance of Cytokeratin 20-positive lymph node vascular endothelial growth factor A mRNA and chromodomain helicase DNA binding protein 4 in pN0 colorectal cancer patients |
https://doi.org/10.18632/oncotarget.23424
Sze Chuen Cesar Wong,
Moon Tong Cheung,
Lewis Lai Yin Luk,
Vivian Ha Man Lee,
Pak Tat Chan,
Hin Fung Andy Tsang,
Evelyn Yin Kwan Wong,
Vivian Weiwen Xue,
Amanda Kit Ching Chan,
and John Kwok Cheung Chan
|
6737-6751 |
Plasma YKL-40 as a biomarker for bevacizumab efficacy in patients with newly diagnosed glioblastoma in the phase 3 randomized AVAglio trial
Plasma YKL-40 as a biomarker for bevacizumab efficacy in patients with newly diagnosed glioblastoma in the phase 3 randomized AVAglio trial |
https://doi.org/10.18632/oncotarget.22886
Mogens K. Boisen,
Camilla B. Holst,
Nicola Consalvo,
Olivier L. Chinot,
and Julia S. Johansen
|
6752-6762 |
Distinct pattern of cerebral blood flow alterations specific to schizophrenics experiencing auditory verbal hallucinations with and without insight: a pilot study
Distinct pattern of cerebral blood flow alterations specific to schizophrenics experiencing auditory verbal hallucinations with and without insight: a pilot study |
https://doi.org/10.18632/oncotarget.23631
Rixing Jing,
Jiangjie Huang,
Deguo Jiang,
Xiaodong Lin,
Xiaolei Ma,
Hongjun Tian,
Jie Li,
and Chuanjun Zhuo
|
6763-6770 |
Kanglaite inhibits EMT caused by TNF-α via NF-κΒ inhibition in colorectal cancer cells
Kanglaite inhibits EMT caused by TNF-α via NF-κΒ inhibition in colorectal cancer cells |
https://doi.org/10.18632/oncotarget.23645
Guiling Shi,
Xiaoli Zheng,
Shiwu Zhang,
Xiaojing Wu,
Fei Yu,
Yijia Wang,
and Fei Xing
|
6771-6779 |
Inferring modes of evolution from colorectal cancer with residual polyp of origin
Inferring modes of evolution from colorectal cancer with residual polyp of origin |
https://doi.org/10.18632/oncotarget.23687
Minsoo Kim,
Brooke R. Druliner,
Nikolaos Vasmatzis,
Taejeong Bae,
Nicholas Chia,
Alexej Abyzov,
and Lisa A. Boardman
|
6780-6792 |
The SNPs in pre-miRNA are related to the response of capecitabine-based therapy in advanced colon cancer patients
The SNPs in pre-miRNA are related to the response of capecitabine-based therapy in advanced colon cancer patients |
https://doi.org/10.18632/oncotarget.23190
Yong Mao,
Chengda Zou,
Fanyi Meng,
Jiehong Kong,
Weipeng Wang,
and Dong Hua
|
6793-6799 |
Identification of the potential crucial genes in invasive ductal carcinoma using bioinformatics analysis
Identification of the potential crucial genes in invasive ductal carcinoma using bioinformatics analysis |
https://doi.org/10.18632/oncotarget.23239
Chunguang Li,
Liangtao Luo,
Sheng Wei,
and Xiongbiao Wang
|
6800-6813 |
Toll-like receptor 2 induces adenosine receptor A2a and promotes human squamous carcinoma cell growth via extracellular signal regulated kinases ½
Toll-like receptor 2 induces adenosine receptor A2a and promotes human squamous carcinoma cell growth via extracellular signal regulated kinases ½ |
https://doi.org/10.18632/oncotarget.23784
Chithra Devi Palani,
Lalitha Ramanathapuram,
Aroonwan Lam-ubol,
and Zoya B. Kurago
|
6814-6829 |
Characterization of aptamer-mediated gene delivery system for liver cancer therapy
Characterization of aptamer-mediated gene delivery system for liver cancer therapy |
https://doi.org/10.18632/oncotarget.23564
Zhongbing Liu,
Xiaoduan Sun,
Shuangli Xiao,
Yan Lin,
Chunhong Li,
Na Hao,
Meiling Zhou,
Ruolan Deng,
Siyun Ke,
and Zhirong Zhong
|
6830-6840 |
Determinants of variability of five programmed death ligand-1 immunohistochemistry assays in non-small cell lung cancer samples
Determinants of variability of five programmed death ligand-1 immunohistochemistry assays in non-small cell lung cancer samples |
https://doi.org/10.18632/oncotarget.23827
Ross A Soo,
Joey Sze Yun Lim,
Bernadette Reyna Asuncion,
Zul Fazreen,
Maria Cynthia Herrera,
Mohd Feroz Mohd Omar,
Nguyen Hoang Diem Phuong,
Ju Ee Seet,
Benhur Amanuel,
Barry Iacopetta,
David Byrne,
Shona Hendry,
Stephen Fox,
and Richie Soong
|
6841-6851 |
Effects of STC1 overexpression on tumorigenicity and metabolism of hepatocellular carcinoma
Effects of STC1 overexpression on tumorigenicity and metabolism of hepatocellular carcinoma |
https://doi.org/10.18632/oncotarget.23566
Cherry CT Leung,
and Chris KC Wong
|
6852-6861 |
A robust gene expression-based prognostic risk score predicts overall survival of lung adenocarcinoma patients
A robust gene expression-based prognostic risk score predicts overall survival of lung adenocarcinoma patients |
https://doi.org/10.18632/oncotarget.23490
En-Guo Chen,
Pin Wang,
Haizhou Lou,
Yunshan Wang,
Hong Yan,
Lei Bi,
Liang Liu,
Bin Li,
Antoine M. Snijders,
Jian-Hua Mao,
and Bo Hang
|
6862-6871 |
Dynamic changes in CD44v-positive cells after preoperative anti-HER2 therapy and its correlation with pathologic complete response in HER2-positive breast cancer
Dynamic changes in CD44v-positive cells after preoperative anti-HER2 therapy and its correlation with pathologic complete response in HER2-positive breast cancer |
https://doi.org/10.18632/oncotarget.23914
Teruo Yamauchi,
Jose Rodrigo Espinosa Fernandez,
Chiyo K. Imamura,
Hideko Yamauchi,
Hiromitsu Jinno,
Maiko Takahashi,
Yuko Kitagawa,
Seigo Nakamura,
Bora Lim,
Savitri Krishnamurthy,
James M. Reuben,
Diane Liu,
Debasish Tripathy,
Helen Chen,
Naoko Takebe,
Hideyuki Saya,
and Naoto T. Ueno
|
6872-6882 |
Temozolomide, sirolimus and chloroquine is a new therapeutic combination that synergizes to disrupt lysosomal function and cholesterol homeostasis in GBM cells
Temozolomide, sirolimus and chloroquine is a new therapeutic combination that synergizes to disrupt lysosomal function and cholesterol homeostasis in GBM cells |
https://doi.org/10.18632/oncotarget.23855
Sanford P.C. Hsu,
John S. Kuo,
Hsin-Chien Chiang,
Hsin-Ell Wang,
Yu-Shan Wang,
Cheng-Chung Huang,
Yi-Chun Huang,
Mau-Shin Chi,
. P. Mehta,
and Kwan-Hwa Chi
|
6883-6896 |
SMAD4-independent activation of TGF-β signaling by MUC1 in a human pancreatic cancer cell line
SMAD4-independent activation of TGF-β signaling by MUC1 in a human pancreatic cancer cell line |
https://doi.org/10.18632/oncotarget.23966
Priyanka Grover,
Sritama Nath,
Monica D. Nye,
Ru Zhou,
Mohammad Ahmad,
and Pinku Mukherjee
|
6897-6910 |
Socioeconomic status is inversely associated with esophageal squamous cell carcinoma risk: results from a population-based case-control study in China
Socioeconomic status is inversely associated with esophageal squamous cell carcinoma risk: results from a population-based case-control study in China |
https://doi.org/10.18632/oncotarget.24003
Peipei Gao,
Xiaorong Yang,
Chen Suo,
Ziyu Yuan,
Hongwei Cheng,
Yuechan Zhang,
Li Jin,
Ming Lu,
Xingdong Chen,
and Weimin Ye
|
6911-6923 |
ZB716, a steroidal selective estrogen receptor degrader (SERD), is orally efficacious in blocking tumor growth in mouse xenograft models
ZB716, a steroidal selective estrogen receptor degrader (SERD), is orally efficacious in blocking tumor growth in mouse xenograft models |
https://doi.org/10.18632/oncotarget.24023
Shanchun Guo,
Changde Zhang,
Melyssa Bratton,
Madhusoodanan Mottamal,
Jiawang Liu,
Peng Ma,
Shilong Zheng,
Qiu Zhong,
Lin Yang,
Thomas E. Wiese,
Yong Wu,
Matthew J. Ellis,
Margarite Matossian,
Matthew E. Burow,
Lucio Miele,
Rene Houtman,
and Guangdi Wang
|
6924-6937 |
Spiclomazine displays a preferential anti-tumor activity in mutant KRas-driven pancreatic cancer
Spiclomazine displays a preferential anti-tumor activity in mutant KRas-driven pancreatic cancer |
https://doi.org/10.18632/oncotarget.24025
Xiaoyu Guo,
Wenjing Zhao,
Zuojia Liu,
and Jin Wang
|
6938-6951 |
In vitro, in vivo and ex vivo demonstration of the antitumoral role of hypocretin-1/orexin-A and almorexant in pancreatic ductal adenocarcinoma
In vitro, in vivo and ex vivo demonstration of the antitumoral role of hypocretin-1/orexin-A and almorexant in pancreatic ductal adenocarcinoma |
https://doi.org/10.18632/oncotarget.24084
Stéphanie Dayot,
Daniela Speisky,
Anne Couvelard,
Pierre Bourgoin,
Valérie Gratio,
Jérôme Cros,
Vinciane Rebours,
Alain Sauvanet,
Pierre Bedossa,
Valérie Paradis,
Philippe Ruszniewski,
Alain Couvineau,
and Thierry Voisin
|
6952-6967 |
The modified glasgow prognostic score is an independent prognostic indicator in neoadjuvantly treated adenocarcinoma of the esophagogastric junction
The modified glasgow prognostic score is an independent prognostic indicator in neoadjuvantly treated adenocarcinoma of the esophagogastric junction |
https://doi.org/10.18632/oncotarget.24087
Gerd Jomrich,
Marlene Hollenstein,
Maximilian John,
Andreas Baierl,
Matthias Paireder,
Ivan Kristo,
Aysegül Ilhan-Mutlu,
Reza Asari,
Matthias Preusser,
and Sebastian F. Schoppmann
|
6968-6976 |
Distinct expression of CDCA3, CDCA5, and CDCA8 leads to shorter relapse free survival in breast cancer patient
Distinct expression of CDCA3, CDCA5, and CDCA8 leads to shorter relapse free survival in breast cancer patient |
https://doi.org/10.18632/oncotarget.24059
Nam Nhut Phan,
Chih-Yang Wang,
Kuan-Lun Li,
Chien-Fu Chen,
Chung-Chieh Chiao,
Han-Gang Yu,
Pung-Ling Huang,
and Yen-Chang Lin
|
6977-6992 |
A comparative study of PD-L1 immunohistochemical assays with four reliable antibodies in thymic carcinoma
A comparative study of PD-L1 immunohistochemical assays with four reliable antibodies in thymic carcinoma |
https://doi.org/10.18632/oncotarget.24075
Tadashi Sakane,
Takayuki Murase,
Katsuhiro Okuda,
Hisashi Takino,
Ayako Masaki,
Risa Oda,
Takuya Watanabe,
Osamu Kawano,
Hiroshi Haneda,
Satoru Moriyama,
Yushi Saito,
Takeshi Yamada,
Ryoichi Nakanishi,
and Hiroshi Inagaki
|
6993-7009 |
The prognostic efficacy of cell-free DNA hypermethylation in colorectal cancer
The prognostic efficacy of cell-free DNA hypermethylation in colorectal cancer |
https://doi.org/10.18632/oncotarget.24097
Simon Ladefoged Rasmussen,
Henrik Bygum Krarup,
Kåre Gotschalck Sunesen,
Martin Berg Johansen,
Mogens Tornby Stender,
Inge Søkilde Pedersen,
Poul Henning Madsen,
and Ole Thorlacius-Ussing
|
7010-7022 |
Metformin inhibits TGF-β1-induced epithelial-to-mesenchymal transition-like process and stem-like properties in GBM via AKT/mTOR/ZEB1 pathway
Metformin inhibits TGF-β1-induced epithelial-to-mesenchymal transition-like process and stem-like properties in GBM via AKT/mTOR/ZEB1 pathway |
https://doi.org/10.18632/oncotarget.23317
Yang Song,
Yong Chen,
Yunqian Li,
Xiaoyan Lyu,
Jiayue Cui,
Ye Cheng,
Liyan Zhao,
and Gang Zhao
|
7023-7035 |
Challenges in using liquid biopsies for gene expression profiling
Challenges in using liquid biopsies for gene expression profiling |
https://doi.org/10.18632/oncotarget.24140
Tania B. Porras,
Pushpinder Kaur,
Alexander Ring,
Naomi Schechter,
and Julie E. Lang
|
7036-7053 |
Identification and characterisation of NANOG+/ OCT-4high/SOX2+ doxorubicin-resistant stem-like cells from transformed trophoblastic cell lines
Identification and characterisation of NANOG+/ OCT-4high/SOX2+ doxorubicin-resistant stem-like cells from transformed trophoblastic cell lines |
https://doi.org/10.18632/oncotarget.24151
Reham M. Balahmar,
David J. Boocock,
Clare Coveney,
Sankalita Ray,
Jayakumar Vadakekolathu,
Tarik Regad,
Selman Ali,
and Shiva Sivasubramaniam
|
7054-7065 |
Genetic polymorphisms in HLA-DP and STAT4 are associated with IgA nephropathy in a Southwest Chinese population
Genetic polymorphisms in HLA-DP and STAT4 are associated with IgA nephropathy in a Southwest Chinese population |
https://doi.org/10.18632/oncotarget.23829
Bin Yang,
Junlong Zhang,
Xinle Liu,
Zhuochun Huang,
Zhenzhen Su,
Yun Liao,
and Lanlan Wang
|
7066-7074 |
Reverting iodine avidity of radioactive-iodine refractory thyroid cancer with a new tyrosine kinase inhibitor (K905-0266) excavated by high-throughput NIS (sodium iodide symporter) enhancer screening platform using dual reporter gene system
Reverting iodine avidity of radioactive-iodine refractory thyroid cancer with a new tyrosine kinase inhibitor (K905-0266) excavated by high-throughput NIS (sodium iodide symporter) enhancer screening platform using dual reporter gene system |
https://doi.org/10.18632/oncotarget.24159
Ji Min Oh,
Senthilkumar Kalimuthu,
Prakash Gangadaran,
Se Hwan Baek,
Liya Zhu,
Ho Won Lee,
Ramya Lakshmi Rajendran,
Chae Moon Hong,
Shin Young Jeong,
Sang-Woo Lee,
Jaetae Lee,
and Byeong-Cheol Ahn
|
7075-7087 |
Diffusion-weighted imaging in identifying breast cancer pathological response to neoadjuvant chemotherapy: A meta-analysis
Diffusion-weighted imaging in identifying breast cancer pathological response to neoadjuvant chemotherapy: A meta-analysis |
https://doi.org/10.18632/oncotarget.23195
Wei Chu,
Weiwei Jin,
Daihong Liu,
Jian Wang,
Chengjun Geng,
Lihua Chen,
and Xuequan Huang
|
7088-7100 |
Meta-analysis of a 10-plex urine-based biomarker assay for the detection of bladder cancer
Meta-analysis of a 10-plex urine-based biomarker assay for the detection of bladder cancer |
https://doi.org/10.18632/oncotarget.23872
Norihiko Masuda,
Osamu Ogawa,
Meyeon Park,
Alvin Y. Liu,
Steve Goodison,
Yunfeng Dai,
Landon Kozai,
Hideki Furuya,
Yair Lotan,
Charles J. Rosser,
and Takashi Kobayashi
|
7101-7111 |
Efficacy and safety of thrombopoietin receptor agonists in children with chronic immune thrombocytopenia: a meta-analysis
Efficacy and safety of thrombopoietin receptor agonists in children with chronic immune thrombocytopenia: a meta-analysis |
https://doi.org/10.18632/oncotarget.23487
Jian-Chun Guo,
Yi Zheng,
Hai-Tao Chen,
Haixia Zhou,
Xian-Hui Huang,
Li-Ping Zhong,
Huai-Bin Zhou,
Yu Huang,
Dan-Li Xie,
and Yong-Liang Lou
|
7112-7125 |
Milk/dairy products consumption and gastric cancer: an update meta-analysis of epidemiological studies
Milk/dairy products consumption and gastric cancer: an update meta-analysis of epidemiological studies |
https://doi.org/10.18632/oncotarget.23496
Shuai Wang,
Mi Zhou,
Alin Ji,
Dahong Zhang,
and Jinjing He
|
7126-7135 |
Vitamin D receptor Taq I polymorphism and the risk of prostate cancer: a meta-analysis
Vitamin D receptor Taq I polymorphism and the risk of prostate cancer: a meta-analysis |
https://doi.org/10.18632/oncotarget.23606
Shaosan Kang,
Yansheng Zhao,
Lei Wang,
Jian Liu,
Xi Chen,
Xiaofeng Liu,
Zhijie Shi,
Weixing Gao,
and Fenghong Cao
|
7136-7147 |
Gemcitabine-based chemotherapy as a viable option for treatment of advanced breast cancer patients: a meta-analysis and literature review
Gemcitabine-based chemotherapy as a viable option for treatment of advanced breast cancer patients: a meta-analysis and literature review |
https://doi.org/10.18632/oncotarget.23426
Zhibo Xie,
Yifan Zhang,
Chen Jin,
and Deliang Fu
|
7148-7161 |
Pharmacokinetic properties of radiolabeled mutant Interleukin-2v: a PET imaging study
Pharmacokinetic properties of radiolabeled mutant Interleukin-2v: a PET imaging study |
https://doi.org/10.18632/oncotarget.23852
Siddesh V. Hartimath,
Valeria Manuelli,
Rolf Zijlma,
Alberto Signore,
Tapan K. Nayak,
Anne Freimoser-Grundschober,
Christian Klein,
Rudi A.J.O. Dierckx,
and Erik F.J.
|
7162-7174 |
Apatinib as a third- or further- line treatment in patients with advanced NSCLC harboring wild-type EGFR
Apatinib as a third- or further- line treatment in patients with advanced NSCLC harboring wild-type EGFR |
https://doi.org/10.18632/oncotarget.23612
Shencun Fang,
Meiling Zhang,
Guihong Wei,
and Kai-Hua Lu
|
7175-7181 |
A liquid biopsy for bronchopulmonary/lung carcinoid diagnosis
A liquid biopsy for bronchopulmonary/lung carcinoid diagnosis |
https://doi.org/10.18632/oncotarget.23820
Mark Kidd,
Irvin M. Modlin,
Ignat Drozdov,
Harry Aslanian,
Lisa Bodei,
Somer Matar,
and Kyung-Min Chung
|
7182-7196 |
The outcomes and prognostic factors of acute respiratory failure in the patients 90 years old and over
The outcomes and prognostic factors of acute respiratory failure in the patients 90 years old and over |
https://doi.org/10.18632/oncotarget.24051
Wan-Ling Chen,
Chin-Ming Chen,
Shu-Chen Kung,
Ching-Min Wang,
Chih-Cheng Lai,
and Chien-Ming Chao
|
7197-7203 |
Inflammatory responses and inflammation-associated diseases in organs
Inflammatory responses and inflammation-associated diseases in organs |
https://doi.org/10.18632/oncotarget.23208
Linlin Chen,
Huidan Deng,
Hengmin Cui,
Jing Fang,
Zhicai Zuo,
Junliang Deng,
Yinglun Li,
Xun Wang,
and Ling Zhao
|
7204-7218 |
New extracellular factors in glioblastoma multiforme development: neurotensin, growth differentiation factor-15, sphingosine-1-phosphate and cytomegalovirus infection
New extracellular factors in glioblastoma multiforme development: neurotensin, growth differentiation factor-15, sphingosine-1-phosphate and cytomegalovirus infection |
https://doi.org/10.18632/oncotarget.24102
Jan Korbecki,
Izabela Gutowska,
Ireneusz Kojder,
Dariusz Jeżewski,
Marta Goschorska,
Agnieszka Łukomska,
Anna Lubkowska,
Dariusz Chlubek,
and Irena Baranowska-Bosiacka
|
7219-7270 |
Correction: Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress
Correction: Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress |
https://doi.org/10.18632/oncotarget.24288
Xiangyun Li,
Mei Li,
Hang Ruan,
Wei Qiu,
Xiang Xu,
Lin Zhang,
and Jian Yu
|
7271-7271 |