Oncotarget

January 12, 2018

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About The Cover

The cover for issue 4 of Oncotarget features Figure 1, "Niclosamide effectively and selectively inhibits viability of AML cells," from Chae, et al.

Table of Contents

Editorial

What is treatment free remission in chronic myeloid leukemia?

What is treatment free remission in chronic myeloid leukemia?

https://doi.org/10.18632/oncotarget.23398

Delphine Rea, Gabriel Etienne,  and François-Xavier Mahon
4279-4279
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Targeting PR1 in myeloid leukemia

Targeting PR1 in myeloid leukemia

https://doi.org/10.18632/oncotarget.23403

Gheath Alatrash, Jeffrey J. Molldrem,  and Muzaffar H. Qazilbas
4280-4281
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Priority Research Papers

Progesterone receptor isoforms, agonists and antagonists differentially reprogram estrogen signaling

Progesterone receptor isoforms, agonists and antagonists differentially reprogram estrogen signaling

https://doi.org/10.18632/oncotarget.21378

Hari Singhal, Marianne E. Greene, Allison L. Zarnke, Muriel Laine, Rose Al Abosy, Ya-Fang Chang, Anna G. Dembo, Kelly Schoenfelt, Raga Vadhi, Xintao Qiu, Prakash Rao, Bindu Santhamma, Hareesh B. Nair, Klaus J. Nickisch, Henry W. Long, Lev Becker, Myles Brown,  and Geoffrey L. Greene
4282-4300
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Niclosamide suppresses acute myeloid leukemia cell proliferation through inhibition of CREB-dependent signaling pathways

Niclosamide suppresses acute myeloid leukemia cell proliferation through inhibition of CREB-dependent signaling pathways

https://doi.org/10.18632/oncotarget.23794

Hee-Don Chae, Nick Cox, Gary V. Dahl, Norman J. Lacayo, Kara L. Davis, Samanta Capolicchio, Mark Smith,  and Kathleen M. Sakamoto
4301-4317
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Research Papers: Immunology

Sodium fluoride causes hepatocellular S-phase arrest by activating ATM-p53-p21 and ATR-Chk1-Cdc25A pathways in mice

Sodium fluoride causes hepatocellular S-phase arrest by activating ATM-p53-p21 and ATR-Chk1-Cdc25A pathways in mice

https://doi.org/10.18632/oncotarget.23093

Huan Liu, Qin Luo, Hengmin Cui, Huidan Deng, Ping Kuang, Yujiao Lu, Jing Fang, Zhicai Zuo, Junliang Deng, Yinglun Li, Xun Wang,  and Ling Zhao
4318-4337
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Research Papers

Overexpression of β1 integrin contributes to polarity reversal and a poor prognosis of breast invasive micropapillary carcinoma

Overexpression of β1 integrin contributes to polarity reversal and a poor prognosis of breast invasive micropapillary carcinoma

https://doi.org/10.18632/oncotarget.22774

Bingbing Liu, Xia Zheng, Fanfan Meng, Yunwei Han, Yawen Song, Fangfang Liu, Shuai Li, Lanjing Zhang, Feng Gu, Xinmin Zhang,  and Li Fu
4338-4353
Abstract  |  PDF  |  HTML  |  How to cite

Discovery and functional implications of a miR-29b-1/miR-29a cluster polymorphism in acute myeloid leukemia

Discovery and functional implications of a miR-29b-1/miR-29a cluster polymorphism in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.23150

Apollinaire Ngankeu, Parvathi Ranganathan, Violaine Havelange, Deedra Nicolet, Stefano Volinia, Bayard L. Powell, Jonathan E. Kolitz, Geoffrey L. Uy, Richard M. Stone, Steven M. Kornblau, Michael Andreeff, Carlo M. Croce, Clara D. Bloomfield,  and Ramiro Garzon
4354-4365
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Genetic and functional analysis of two missense DUOX2 mutations in congenital hypothyroidism and goiter

Genetic and functional analysis of two missense DUOX2 mutations in congenital hypothyroidism and goiter

https://doi.org/10.18632/oncotarget.10525

Shiguo Liu, Wenhui Zhang, Liqin Zhang, Hui Zou, Kunna Lu, Qiang Li, Hongfei Xia, Shengli Yan,  and Xu Ma
4366-4374
Abstract  |  PDF  |  HTML  |  How to cite

Clinical and molecular features of innate and acquired resistance to anti-PD-1/PD-L1 therapy in lung cancer

Clinical and molecular features of innate and acquired resistance to anti-PD-1/PD-L1 therapy in lung cancer

https://doi.org/10.18632/oncotarget.23315

Shalin Shah, Kevin Wood, Brian Labadie, Brian Won, Ryan Brisson, Theodore Karrison, Thomas Hensing, Mark Kozloff, Riyue Bao, Jyoti D. Patel,  and Jason J. Luke
4375-4384
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Transfusion-associated adverse reactions (TAARs) and cytokine accumulations in the stored blood components: the impact of prestorage versus poststorage leukoreduction

Transfusion-associated adverse reactions (TAARs) and cytokine accumulations in the stored blood components: the impact of prestorage versus poststorage leukoreduction

https://doi.org/10.18632/oncotarget.23136

Chih-Chun Chang, Tai-Chen Lee, Ming-Jang Su, Hsiu-Chen Lin, Fang-Yi Cheng, Yi-Ting Chen, Tzung-Hai Yen,  and Fang-Yeh Chu
4385-4394
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Impact of DLK1-DIO3 imprinted cluster hypomethylation in smoker patients with lung cancer

Impact of DLK1-DIO3 imprinted cluster hypomethylation in smoker patients with lung cancer

https://doi.org/10.18632/oncotarget.10611

Sonia Molina-Pinelo, Ana Salinas, Nicolás Moreno-Mata, Irene Ferrer, Rocío Suarez, Eduardo Andrés-León, Manuel Rodríguez-Paredes, Julian Gutekunst, Eloisa Jantus-Lewintre, Carlos Camps, Amancio Carnero,  and Luis Paz-Ares
4395-4410
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

LncRNA MALAT1 regulates smooth muscle cell phenotype switch via activation of autophagy

LncRNA MALAT1 regulates smooth muscle cell phenotype switch via activation of autophagy

https://doi.org/10.18632/oncotarget.23230

Tie-Feng Song, Li-Wen Huang, Ying Yuan, Hui-qin Wang, Hong-Peng He, Wen-Jian Ma, Li-Hong Huo, Hao Zhou, Nan Wang,  and Tong-Cun Zhang
4411-4426
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Comparative gene expression profiling of human metallothionein-3 up-regulation in neuroblastoma cells and its impact on susceptibility to cisplatin

Comparative gene expression profiling of human metallothionein-3 up-regulation in neuroblastoma cells and its impact on susceptibility to cisplatin

https://doi.org/10.18632/oncotarget.23333

Miguel Angel Merlos Rodrigo, Simona Dostalova, Hana Buchtelova, Vladislav Strmiska, Petr Michalek, Sona Krizkova, Ales Vicha, Pavla Jencova, Tomas Eckschlager, Marie Stiborova, Zbynek Heger,  and Vojtech Adam
4427-4439
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

RAS GTPases are modified by SUMOylation

RAS GTPases are modified by SUMOylation

https://doi.org/10.18632/oncotarget.23269

Byeong Hyeok Choi, Changyan Chen, Mark Philips,  and Wei Dai
4440-4450
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Fibrosis-related miRNAs as serum biomarkers for pancreatic ductal adenocarcinoma

Fibrosis-related miRNAs as serum biomarkers for pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.23377

Rei Suzuki, Hiroyuki Asama, Yuichi Waragai, Tadayuki Takagi, Takuto Hikichi, Mitsuru Sugimoto, Naoki Konno, Ko Watanabe, Jun Nakamura, Hitomi Kikuchi, Yuki Sato, Shigeru Marubashi, Atsushi Masamune,  and Hiromasa Ohira
4451-4460
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

The inhibition of PLCγ1 protects chondrocytes against osteoarthritis, implicating its binding to Akt

The inhibition of PLCγ1 protects chondrocytes against osteoarthritis, implicating its binding to Akt

https://doi.org/10.18632/oncotarget.23286

Heguo Cai, Ning Qu, Xiaolei Chen, Yang Zhou, Xinpeng Zheng, Bing Zhang,  and Chun Xia
4461-4474
Abstract  |  PDF  |  HTML  |  How to cite

Replication of hepatitis E virus in the ovary and promotion of oocyte apoptosis in rabbits infected with HEV-4

Replication of hepatitis E virus in the ovary and promotion of oocyte apoptosis in rabbits infected with HEV-4

https://doi.org/10.18632/oncotarget.23381

Junqing An, Tianlong Liu, Ruiping She, Qiaoxing Wu, Jijing Tian, Ruihan Shi, Wenzhuo Hao, Xinxin Ren, Yue Yang, Yiyao Lu, Yifei Yang,  and Yuanheng Wu
4475-4484
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Assessment of folate receptor alpha and beta expression in selection of lung and pancreatic cancer patients for receptor targeted therapies

Assessment of folate receptor alpha and beta expression in selection of lung and pancreatic cancer patients for receptor targeted therapies

https://doi.org/10.18632/oncotarget.23321

Jiayin Shen, Yingwen Hu, Karson S. Putt, Sunil Singhal, Haiyong Han, Daniel W. Visscher, Linda M. Murphy,  and Philip S. Low
4485-4495
Abstract  |  PDF  |  HTML  |  How to cite

A dual mechanism of activation of the Sonic Hedgehog pathway in anaplastic thyroid cancer: crosstalk with RAS-BRAF-MEK pathway and ligand secretion by tumor stroma

A dual mechanism of activation of the Sonic Hedgehog pathway in anaplastic thyroid cancer: crosstalk with RAS-BRAF-MEK pathway and ligand secretion by tumor stroma

https://doi.org/10.18632/oncotarget.23388

Alessia Parascandolo, Mikko O. Laukkanen, Nancy De Rosa, Clara Ugolini, Maria Carmela Cantisani, Anna Maria Cirafici, Fulvio Basolo, Massimo Santoro,  and Maria Domenica Castellone
4496-4510
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

AMPK activation by Tanshinone IIA protects neuronal cells from oxygen-glucose deprivation

AMPK activation by Tanshinone IIA protects neuronal cells from oxygen-glucose deprivation

https://doi.org/10.18632/oncotarget.23391

Yingfeng Weng, Jixian Lin, Hui Liu, Hui Wu, Zhimin Yan,  and Jing zhao
4511-4521
Abstract  |  PDF  |  HTML  |  How to cite

Lipidomics reveals altered biosynthetic pathways of glycerophospholipids and cell signaling as biomarkers of the polycystic ovary syndrome

Lipidomics reveals altered biosynthetic pathways of glycerophospholipids and cell signaling as biomarkers of the polycystic ovary syndrome

https://doi.org/10.18632/oncotarget.23393

Mariona Jové, Irene Pradas, Alba Naudí, Susana Rovira-Llopis, Celia Bañuls, Milagros Rocha, Manuel Portero-Otin, Antonio Hernández-Mijares, Victor M. Victor,  and Reinald Pamplona
4522-4536
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

APOBEC-mediated mutagenesis in urothelial carcinoma is associated with improved survival, mutations in DNA damage response genes, and immune response

APOBEC-mediated mutagenesis in urothelial carcinoma is associated with improved survival, mutations in DNA damage response genes, and immune response

https://doi.org/10.18632/oncotarget.23344

Alexander P. Glaser, Damiano Fantini, Yiduo Wang, Yanni Yu, Kalen J. Rimar, Joseph R. Podojil, Stephen D. Miller,  and Joshua J. Meeks
4537-4548
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Signature of survival: a 18F-FDG PET based whole-liver radiomic analysis predicts survival after 90Y-TARE for hepatocellular carcinoma

Signature of survival: a 18F-FDG PET based whole-liver radiomic analysis predicts survival after 90Y-TARE for hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.23423

Paul Blanc-Durand, Axel Van Der Gucht, Mario Jreige, Marie Nicod-Lalonde, Marina Silva-Monteiro, John O. Prior, Alban Denys, Adrien Depeursinge,  and Niklaus Schaefer
4549-4558
Abstract  |  PDF  |  HTML  |  How to cite

Adduction to arginine detoxifies aflatoxin B1 by eliminating genotoxicity and altering in vitro toxicokinetic profiles

Adduction to arginine detoxifies aflatoxin B1 by eliminating genotoxicity and altering in vitro toxicokinetic profiles

https://doi.org/10.18632/oncotarget.23382

Blake R. Rushing,  and Mustafa I. Selim
4559-4570
Abstract  |  PDF  |  HTML  |  How to cite

Inhibition of autophagy-attenuated calcium oxalate crystal-induced renal tubular epithelial cell injury in vivo and in vitro

Inhibition of autophagy-attenuated calcium oxalate crystal-induced renal tubular epithelial cell injury in vivo and in vitro

https://doi.org/10.18632/oncotarget.23383

Yunlong Liu, Derong Li, Ziqi He, Quan Liu, Jihua Wu, Xiaofeng Guan, Zhiwei Tao,  and Yaoliang Deng
4571-4582
Abstract  |  PDF  |  HTML  |  How to cite

Quantitative metabolomics for investigating the value of polyamines in the early diagnosis and therapy of colorectal cancer

Quantitative metabolomics for investigating the value of polyamines in the early diagnosis and therapy of colorectal cancer

https://doi.org/10.18632/oncotarget.22885

Ran Liu, Xiaohui Lin, Zuojing Li, Qing Li,  and Kaishun Bi
4583-4592
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

α-Tocopherol succinate enhances pterostilbene anti-tumor activity in human breast cancer cells in vivo and in vitro

α-Tocopherol succinate enhances pterostilbene anti-tumor activity in human breast cancer cells in vivo and in vitro

https://doi.org/10.18632/oncotarget.23390

Ka-Wai Tam, Chi-Tang Ho, Shih-Hsin Tu, Wen-Jui Lee, Ching-Shui Huang, Ching-Shyang Chen, Chih-Hsiung Wu, Chia-Hwa Lee,  and Yuan-Soon Ho
4593-4606
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Prognostic factors for olfactory groove meningioma with nasal cavity extension

Prognostic factors for olfactory groove meningioma with nasal cavity extension

https://doi.org/10.18632/oncotarget.23461

Ji Zhang, Ke Sai, Zheng-Quan Zhu, Fu Hua Lin, Zi-Feng Wang, Yong-Ming Chen, Chun-Yu Huang, Yun-Lin Ye, Xiao-Li Wang, You-Ping Li, Shu-Xin Sun, Wei-Ying Zhong, Jian-Bin Chen,  and Yun-Qiang Yang
4607-4613
Abstract  |  PDF  |  HTML  |  How to cite

Computational methods reveal novel functionalities of PIWI-interacting RNAs in human papillomavirus-induced head and neck squamous cell carcinoma

Computational methods reveal novel functionalities of PIWI-interacting RNAs in human papillomavirus-induced head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.23464

Aswini R. Krishnan, Yuanhao Qu, Pin Xue Li, Angela E. Zou, Joseph A. Califano, Jessica Wang-Rodriguez,  and Weg M. Ongkeko
4614-4624
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

O-linked N-acetylglucosamine transferase enhances secretory clusterin expression via liver X receptors and sterol response element binding protein regulation in cervical cancer

O-linked N-acetylglucosamine transferase enhances secretory clusterin expression via liver X receptors and sterol response element binding protein regulation in cervical cancer

https://doi.org/10.18632/oncotarget.23588

Min Jun Kim, Mee Young Choi, Dong Hoon Lee, Gu Seob Roh, Hyun Joon Kim, Sang Soo Kang, Gyeong Jae Cho, Yoon Sook Kim,  and Wan Sung Choi
4625-4636
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

PD-L1 confers resistance to EGFR mutation-independent tyrosine kinase inhibitors in non-small cell lung cancer via upregulation of YAP1 expression

PD-L1 confers resistance to EGFR mutation-independent tyrosine kinase inhibitors in non-small cell lung cancer via upregulation of YAP1 expression

https://doi.org/10.18632/oncotarget.23161

Jai-Nien Tung, Po-Lin Lin, Yao-Chen Wang, De-Wei Wu, Chi-Yi Chen,  and Huei Lee
4637-4646
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity in VHL-deficient human renal cell carcinoma

Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity in VHL-deficient human renal cell carcinoma

https://doi.org/10.18632/oncotarget.23470

Susan E. Scanlon, Denise C. Hegan, Parker L. Sulkowski,  and Peter M. Glazer
4647-4660
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Elucidating mechanisms of sunitinib resistance in renal cancer: an integrated pathological-molecular analysis

Elucidating mechanisms of sunitinib resistance in renal cancer: an integrated pathological-molecular analysis

https://doi.org/10.18632/oncotarget.23163

Henriett Butz, Qiang Ding, Roy Nofech-Mozes, Zsuzsanna Lichner, Heyu Ni,  and George M. Yousef
4661-4674
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Silver nanoparticles of different sizes induce a mixed type of programmed cell death in human pancreatic ductal adenocarcinoma

Silver nanoparticles of different sizes induce a mixed type of programmed cell death in human pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.22563

Ewelina Zielinska, Agata Zauszkiewicz-Pawlak, Michal Wojcik,  and Iwona Inkielewicz-Stepniak
4675-4697
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Association of SNPs in the TIMP-2 gene and large artery atherosclerotic stroke in southern Chinese Han population

Association of SNPs in the TIMP-2 gene and large artery atherosclerotic stroke in southern Chinese Han population

https://doi.org/10.18632/oncotarget.23473

Tie Guo, Haizhen Hao, Lv Zhou, Feng Zhou,  and Dan Yu
4698-4706
Abstract  |  PDF  |  HTML  |  How to cite

Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer

Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer

https://doi.org/10.18632/oncotarget.23523

Hironori Aoki, Eiichiro Yamamoto, Akira Takasawa, Takeshi Niinuma, Hiro-O Yamano, Taku Harada, Hiro-O Matsushita, Kenjiro Yoshikawa, Ryo Takagi, Eiji Harada, Yoshihito Tanaka, Yuko Yoshida, Tomoyuki Aoyama, Makoto Eizuka, Akira Yorozu, Hiroshi Kitajima, Masahiro Kai, Norimasa Sawada, Tamotsu Sugai, Hiroshi Nakase,  and Hiromu Suzuki
4707-4721
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Activation of MAPK signalling results in resistance to saracatinib (AZD0530) in ovarian cancer

Activation of MAPK signalling results in resistance to saracatinib (AZD0530) in ovarian cancer

https://doi.org/10.18632/oncotarget.23524

Niamh McGivern, Aya El-Helali, Paul Mullan, Iain A. McNeish, D. Paul Harkin, Richard D. Kennedy,  and Nuala McCabe
4722-4736
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Personalized adoptive immunotherapy for patients with EBV-associated tumors and complications: Evaluation of novel naturally processed and presented EBV-derived T-cell epitopes

Personalized adoptive immunotherapy for patients with EBV-associated tumors and complications: Evaluation of novel naturally processed and presented EBV-derived T-cell epitopes

https://doi.org/10.18632/oncotarget.23531

Maren Bieling, Sabine Tischer, Ulrich Kalinke, Rainer Blasczyk, Søren Buus, Britta Maecker-Kolhoff,  and Britta Eiz-Vesper
4737-4757
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing

Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing

https://doi.org/10.18632/oncotarget.23462

Min Shen, Rosita Asawa, Ya-Qin Zhang, Elizabeth Cunningham, Hongmao Sun, Alexander Tropsha, William P. Janzen, Eugene N. Muratov, Stephen J. Capuzzi, Sherif Farag, Ajit Jadhav, Julie Blatt, Anton Simeonov,  and Natalia J. Martinez
4758-4772
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Triplications of human chromosome 21 orthologous regions in mice result in expansion of megakaryocyte-erythroid progenitors and reduction of granulocyte-macrophage progenitors

Triplications of human chromosome 21 orthologous regions in mice result in expansion of megakaryocyte-erythroid progenitors and reduction of granulocyte-macrophage progenitors

https://doi.org/10.18632/oncotarget.23463

Chunhong Liu, Tao Yu, Zhuo Xing, Xiaoling Jiang, Yichen Li, Annie Pao, Justin Mu, Paul K. Wallace, George Stoica, Andrei V. Bakin,  and Y. Eugene Yu
4773-4786
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Induction of endoplasmic reticulum stress and mitochondrial dysfunction dependent apoptosis signaling pathway in human renal cancer cells by norcantharidin

Induction of endoplasmic reticulum stress and mitochondrial dysfunction dependent apoptosis signaling pathway in human renal cancer cells by norcantharidin

https://doi.org/10.18632/oncotarget.23465

Min-Hua Wu, Hui-Ling Chiou, Chu-Liang Lin, Ching-Yi Lin, Shun-Fa Yang,  and Yi-Hsien Hsieh
4787-4797
Abstract  |  PDF  |  HTML  |  How to cite

Co-expression analysis revealed PTCH1-3’UTR promoted cell migration and invasion by activating miR-101-3p/SLC39A6 axis in non-small cell lung cancer: implicating the novel function of PTCH1

Co-expression analysis revealed PTCH1-3’UTR promoted cell migration and invasion by activating miR-101-3p/SLC39A6 axis in non-small cell lung cancer: implicating the novel function of PTCH1

https://doi.org/10.18632/oncotarget.23219

Xuechao Wan, Zhe Kong, Kaili Chu, Chuanyou Yi, Jian Hu, Rui Qin, Chen Zhao, Fangqiu Fu, Hai Wu, Yao Li,  and Yan Huang
4798-4813
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A novel classifier based on three preoperative tumor markers predicting the cancer-specific survival of gastric cancer (CEA, CA19-9 and CA72-4)

A novel classifier based on three preoperative tumor markers predicting the cancer-specific survival of gastric cancer (CEA, CA19-9 and CA72-4)

https://doi.org/10.18632/oncotarget.23307

Jing Guo, Shangxiang Chen, Shun Li, Xiaowei Sun, Wei Li, Zhiwei Zhou, Yingbo Chen,  and Dazhi Xu
4814-4822
Abstract  |  PDF  |  HTML  |  How to cite

miRNA regulation of Tip110 expression and self-renewal and differentiation of human CD34+ hematopoietic cells

miRNA regulation of Tip110 expression and self-renewal and differentiation of human CD34+ hematopoietic cells

https://doi.org/10.18632/oncotarget.23572

Ying Liu, Xinxin Huang, Khalid A. Timani, Hal E. Broxmeyer,  and Johnny J. He
4823-4832
Abstract  |  PDF  |  HTML  |  How to cite

TNF-α inhibits SATB2 expression and osteoblast differentiation through NF-κB and MAPK pathways

TNF-α inhibits SATB2 expression and osteoblast differentiation through NF-κB and MAPK pathways

https://doi.org/10.18632/oncotarget.23373

Chijian Zuo, Xiaoying Zhao, Yu Shi, Wen Wu, Ning Zhang, Jiake Xu, Chuandong Wang, Guoli Hu,  and Xiaoling Zhang
4833-4850
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Upregulation of LncRNA BCYRN1 promotes tumor progression and enhances EpCAM expression in gastric carcinoma

Upregulation of LncRNA BCYRN1 promotes tumor progression and enhances EpCAM expression in gastric carcinoma

https://doi.org/10.18632/oncotarget.23585

Hao Ren, Xiaomin Yang, Yongmei Yang, Xiaoyu Zhang, Rui Zhao, Ran Wei, Xin Zhang,  and Yi Zhang
4851-4861
Abstract  |  PDF  |  HTML  |  How to cite

Morphologic predictors of pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

Morphologic predictors of pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

https://doi.org/10.18632/oncotarget.23419

Chongda Zhang, Feng Ye, Yuan Liu, Han Ouyang, Xinming Zhao,  and Hongmei Zhang
4862-4874
Abstract  |  PDF  |  HTML  |  How to cite

Peptide inhibition of the SETD6 methyltransferase catalytic activity

Peptide inhibition of the SETD6 methyltransferase catalytic activity

https://doi.org/10.18632/oncotarget.23591

Michal Feldman,  and Dan Levy
4875-4885
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

MiR-361-5p suppresses chemoresistance of gastric cancer cells by targeting FOXM1 via the PI3K/Akt/mTOR pathway

MiR-361-5p suppresses chemoresistance of gastric cancer cells by targeting FOXM1 via the PI3K/Akt/mTOR pathway

https://doi.org/10.18632/oncotarget.23513

Lei Tian, Zhifeng Zhao, Ling Xie,  and JinPeng Zhu
4886-4896
Abstract  |  PDF  |  HTML  |  How to cite

Blood-brain barrier disruption induced by diagnostic ultrasound combined with microbubbles in mice

Blood-brain barrier disruption induced by diagnostic ultrasound combined with microbubbles in mice

https://doi.org/10.18632/oncotarget.23527

Bingxia Zhao, Yihan Chen, Jinfeng Liu, Li Zhang, Jing Wang, Yali Yang, Qing Lv,  and Mingxing Xie
4897-4914
Abstract  |  PDF  |  HTML  |  How to cite

Arsenic exposure assists ccm3 genetic polymorphism in elevating blood pressure

Arsenic exposure assists ccm3 genetic polymorphism in elevating blood pressure

https://doi.org/10.18632/oncotarget.23518

Yanfang Gao, Zhiqiang Zhao, Linqing Yang, Xinxia Liu, Xiumei Xing, Huimin Zhang, Jianpei Yun, Xiaoyan Ou, Xiaolin Su, Yao Lu, Yi Sun, Yarui Yang, Jun Jiang, Dong Cui, Zhixiong Zhuang,  and Yun He
4915-4923
Abstract  |  PDF  |  HTML  |  How to cite

miR-30a suppresses lung cancer progression by targeting SIRT1

miR-30a suppresses lung cancer progression by targeting SIRT1

https://doi.org/10.18632/oncotarget.23529

Yaowu Guan, Zhongming Rao,  and Cheng Chen
4924-4934

Heterotypic breast cancer model based on a silk fibroin scaffold to study the tumor microenvironment

Heterotypic breast cancer model based on a silk fibroin scaffold to study the tumor microenvironment

https://doi.org/10.18632/oncotarget.23574

Ewelina Dondajewska, Wojciech Juzwa, Andrzej Mackiewicz,  and Hanna Dams-Kozlowska
4935-4950
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Efficacy of granulocyte-macrophage colony-stimulating factor combined with metronomic paclitaxel in the treatment of Lewis lung carcinoma transplanted in mice

Efficacy of granulocyte-macrophage colony-stimulating factor combined with metronomic paclitaxel in the treatment of Lewis lung carcinoma transplanted in mice

https://doi.org/10.18632/oncotarget.23530

Nengping Zhu, Rongsheng Qin, Qin Zhang, Shaozhi Fu, Shanshan Liu, Yue Chen, Juan Fan,  and Yunwei Han
4951-4960
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Assessment of a new genomic classification system in acute myeloid leukemia with a normal karyotype

Assessment of a new genomic classification system in acute myeloid leukemia with a normal karyotype

https://doi.org/10.18632/oncotarget.23575

Jae-Sook Ahn, Hyeoung-Joon Kim, Yeo-Kyeoung Kim, Seung-Shin Lee, Seo-Yeon Ahn, Sung-Hoon Jung, Deok-Hwan Yang, Je-Jung Lee, Hee Jeong Park, Ja-Yeon Lee, Seung Hyun Choi, Chul Won Jung, Jun-Ho Jang, Hee Je Kim, Joon Ho Moon, Sang Kyun Sohn, Yoo Jin Lee, Jong-Ho Won, Sung-Hyun Kim, Zhaolei Zhang, TaeHyung Kim,  and Dennis Dong Hwan Kim
4961-4968
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Cis-trimethoxy resveratrol induces intrinsic apoptosis via prometaphase arrest and prolonged CDK1 activation pathway in human Jurkat T cells

Cis-trimethoxy resveratrol induces intrinsic apoptosis via prometaphase arrest and prolonged CDK1 activation pathway in human Jurkat T cells

https://doi.org/10.18632/oncotarget.23576

Chae Eun Kim, Do Youn Jun, Jong-Sik Kim,  and Young Ho Kim
4969-4984
Abstract  |  PDF  |  HTML  |  How to cite

The microtubule-associated protein PRC1 is a potential therapeutic target for lung cancer

The microtubule-associated protein PRC1 is a potential therapeutic target for lung cancer

https://doi.org/10.18632/oncotarget.23577

Steffen Hanselmann, Patrick Wolter, Jonas Malkmus,  and Stefan Gaubatz
4985-4997

Osteopontin–integrin engagement induces HIF-1α–TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer

Osteopontin–integrin engagement induces HIF-1α–TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer

https://doi.org/10.18632/oncotarget.23578

Chi-Shuan Fan, Wei-Shone Chen, Li-Li Chen, Chia-Chi Chen, Yu-Ting Hsu, Kee Voon Chua, Horng-Dar Wang,  and Tze-Sing Huang
4998-5015
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Undermining ribosomal RNA transcription in both the nucleolus and mitochondrion: an offbeat approach to target MYC-driven cancer

Undermining ribosomal RNA transcription in both the nucleolus and mitochondrion: an offbeat approach to target MYC-driven cancer

https://doi.org/10.18632/oncotarget.23579

Stefano Rossetti, Andrzej J. Wierzbicki,  and Nicoletta Sacchi
5016-5031
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Comparison of hepatic and serum lipid signatures in hepatocellular carcinoma patients leads to the discovery of diagnostic and prognostic biomarkers

Comparison of hepatic and serum lipid signatures in hepatocellular carcinoma patients leads to the discovery of diagnostic and prognostic biomarkers

https://doi.org/10.18632/oncotarget.23494

Yonghai Lu, Juanjuan Chen, Chong Huang, Ning Li, Li Zou, Sin Eng Chia, Shengsen Chen, Kangkang Yu, Qingxia Ling, Qi Cheng, Mengqi Zhu, Weidong Zhang, Mingquan Chen,  and Choon Nam Ong
5032-5043
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Nonlinear mixed effects dose response modeling in high throughput drug screens: application to melanoma cell line analysis

Nonlinear mixed effects dose response modeling in high throughput drug screens: application to melanoma cell line analysis

https://doi.org/10.18632/oncotarget.23495

Kuan-Fu Ding, Emanuel F. Petricoin, Darren Finlay, Hongwei Yin, William P.D. Hendricks, Chris Sereduk, Jeffrey Kiefer, Aleksandar Sekulic, Patricia M. LoRusso, Kristiina Vuori, Jeffrey M. Trent,  and Nicholas J. Schork
5044-5057
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Prognostic value of PD –L1 expression in patients with primary solid tumors

Prognostic value of PD –L1 expression in patients with primary solid tumors

https://doi.org/10.18632/oncotarget.23580

Xiao Xiang, Peng-Cheng Yu, Di Long, Xiao-Li Liao, Sen Zhang, Xue-Mei You, Jian-Hong Zhong,  and Le-Qun Li
5058-5072
Abstract  |  PDF  |  HTML  |  How to cite

Aberrant frequency of TNFR2+ Treg and related cytokines in patients with CIN and cervical cancer

Aberrant frequency of TNFR2+ Treg and related cytokines in patients with CIN and cervical cancer

https://doi.org/10.18632/oncotarget.23581

Teng Zhang, Jun Jiao, Xinlin Jiao, Lu Zhao, Xinli Tian, Qing Zhang, Daoxin Ma,  and Baoxia Cui
5073-5083
Abstract  |  PDF  |  HTML  |  How to cite

Overexpression of Na+/Mg2+ exchanger SLC41A1 attenuates pro-survival signaling

Overexpression of Na+/Mg2+ exchanger SLC41A1 attenuates pro-survival signaling

https://doi.org/10.18632/oncotarget.23598

Gerhard Sponder, Nasrin Abdulhanan, Nadine Fröhlich, Lucia Mastrototaro, Jörg R. Aschenbach, Monika Röntgen, Ivana Pilchova, Michal Cibulka, Peter Racay,  and Martin Kolisek
5084-5104
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

LncRNA gadd7, increased in varicocele patients, suppresses cell proliferation and promotes cell apoptosis

LncRNA gadd7, increased in varicocele patients, suppresses cell proliferation and promotes cell apoptosis

https://doi.org/10.18632/oncotarget.23696

Jun Zhao, Huan Li, Hao Deng, Li Zhu, Bingyu Zhou, MeiQiong Yang, QianRu Liu, GuoQun Luo, Yunxia Yang,  and WenMin Ma
5105-5110
Abstract  |  PDF  |  HTML  |  How to cite

Acquired resistance to tyrosine kinase inhibitors may be linked with the decreased sensitivity to X-ray irradiation

Acquired resistance to tyrosine kinase inhibitors may be linked with the decreased sensitivity to X-ray irradiation

https://doi.org/10.18632/oncotarget.23700

Maxim Sorokin, Roman Kholodenko, Anna Grekhova, Maria Suntsova, Margarita Pustovalova, Natalia Vorobyeva, Irina Kholodenko, Galina Malakhova, Andrew Garazha, Artem Nedoluzhko, Raif Vasilov, Elena Poddubskaya, Olga Kovalchuk, Leila Adamyan, Vladimir Prassolov, Daria Allina, Denis Kuzmin, Kirill Ignatev, Andreyan Osipov,  and Anton Buzdin
5111-5124
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Pentraxin-3, procalcitonin and lactate as prognostic markers in patients with sepsis and septic shock

Pentraxin-3, procalcitonin and lactate as prognostic markers in patients with sepsis and septic shock

https://doi.org/10.18632/oncotarget.23701

Chenggong Hu, Yongfang Zhou, Chang Liu,  and Yan Kang
5125-5136
Abstract  |  PDF  |  HTML  |  How to cite

Low FAT4 expression is associated with a poor prognosis in gastric cancer patients

Low FAT4 expression is associated with a poor prognosis in gastric cancer patients

https://doi.org/10.18632/oncotarget.23702

Xiaoting Jiang, Zhengchuang Liu, Yingjie Xia, Jungang Luo, Ji Xu, Xujun He,  and Houquan Tao
5137-5154
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

MicroRNA-340 inhibits the proliferation and promotes the apoptosis of colon cancer cells by modulating REV3L

MicroRNA-340 inhibits the proliferation and promotes the apoptosis of colon cancer cells by modulating REV3L

https://doi.org/10.18632/oncotarget.23703

Roshini Arivazhagan, Jaesuk Lee, Delger Bayarsaikhan, Peter Kwak, Myeongjoo Son, Kyunghee Byun, Ghasem Hosseini Salekdeh,  and Bonghee Lee
5155-5168
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis in vivo; therapeutic and chemopreventive applications

Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis in vivo; therapeutic and chemopreventive applications

https://doi.org/10.18632/oncotarget.23704

Niaz Mahmood, David Cheishvili, Ani Arakelian, Imrana Tanvir, Haseeb Ahmed Khan, Anne-Sophie Pépin, Moshe Szyf,  and Shafaat A. Rabbani
5169-5183
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Brucella induces unfolded protein response and inflammatory response via GntR in alveolar macrophages

Brucella induces unfolded protein response and inflammatory response via GntR in alveolar macrophages

https://doi.org/10.18632/oncotarget.23706

Dong Zhou, Fei-Jie Zhi, Mao-Zhen Qi, Fu-Rong Bai, Guangdong Zhang, Jun-Mei Li, Huan Liu, Hua-Tao Chen, Peng-Fei Lin, Ke-Qiong Tang, Wei Liu, Ya-Ping Jin,  and Ai-Hua Wang
5184-5196
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Promiximab-duocarmycin, a new CD56 antibody-drug conjugates, is highly efficacious in small cell lung cancer xenograft models

Promiximab-duocarmycin, a new CD56 antibody-drug conjugates, is highly efficacious in small cell lung cancer xenograft models

https://doi.org/10.18632/oncotarget.23708

Lin Yu, Ying Lu, Yuqin Yao, Yu Liu, Yuxi Wang, Qinhuai Lai, Ruirui Zhang, Wenting Li, Ruixue Wang, Yuyin Fu, Yiran Tao, Shuli Yi, Lantu Gou, Ligong Chen,  and Jinliang Yang
5197-5207
Abstract  |  PDF  |  HTML  |  How to cite

CRISPR knock out of programmed cell death protein 1 enhances anti-tumor activity of cytotoxic T lymphocytes

CRISPR knock out of programmed cell death protein 1 enhances anti-tumor activity of cytotoxic T lymphocytes

https://doi.org/10.18632/oncotarget.23730

Zhilong Zhao, Long Shi, Wei Zhang, Jinsheng Han, Shaohui Zhang, Zexian Fu,  and Jianhui Cai
5208-5215
Abstract  |  PDF  |  HTML  |  How to cite

Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy

Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy

https://doi.org/10.18632/oncotarget.23749

Caroline M. Robb, Smit Kour, Jacob I. Contreras, Ekta Agarwal, Carter J. Barger, Sandeep Rana, Yogesh Sonawane, Beth K. Neilsen, Margaret Taylor, Smitha Kizhake, Rhishikesh N. Thakare, Sanjib Chowdhury, Jing Wang, Jennifer D. Black, Michael A. Hollingsworth, Michael G. Brattain,  and Amarnath Natarajan
5216-5232
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature

REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature

https://doi.org/10.18632/oncotarget.23750

Shavali Shaik, Bridget Kennis, Shinji Maegawa, Keri Schadler, Yang Yanwen, Keri Callegari, Rishi R. Lulla, Stewart Goldman, Javad Nazarian, Veena Rajaram, Jason Fangusaro,  and Vidya Gopalakrishnan
5233-5250
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Carotid artery wall shear stress is independently correlated with renal function in the elderly

Carotid artery wall shear stress is independently correlated with renal function in the elderly

https://doi.org/10.18632/oncotarget.23825

Yuqi Guo, Fang Wei, Juan Wang, Yingxin Zhao, Shangwen Sun, Hua Zhang,  and Zhendong Liu
5251-5262
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Prostate-selective α antagonists increase fracture risk in prostate cancer patients with and without a history of androgen deprivation therapy: a nationwide population-based study

Prostate-selective α antagonists increase fracture risk in prostate cancer patients with and without a history of androgen deprivation therapy: a nationwide population-based study

https://doi.org/10.18632/oncotarget.23828

Wei-Heng Kao, Chang-Fu Kuo, I-Jun Chou, Lai-Chu See, Wen-Kuan Huang, Meng-Jiun Chiou, Weiya Zhang, Michael Doherty, Chun-Chieh Wang, Jun-Te Hsu, Hsien-Hsin Chen,  and Ji-Hong Hong
5263-5273
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Inhibition of the MEK/ERK pathway augments nab-paclitaxel-based chemotherapy effects in preclinical models of pancreatic cancer

Inhibition of the MEK/ERK pathway augments nab-paclitaxel-based chemotherapy effects in preclinical models of pancreatic cancer

https://doi.org/10.18632/oncotarget.23684

Niranjan Awasthi, Sheena Monahan, Alexis Stefaniak, Margaret A. Schwarz,  and Roderich E. Schwarz
5274-5286
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Identifying characteristic miRNAs-genes and risk pathways of multiple sclerosis based on bioinformatics analysis

Identifying characteristic miRNAs-genes and risk pathways of multiple sclerosis based on bioinformatics analysis

https://doi.org/10.18632/oncotarget.23866

Deling Luo,  and Jin Fu
5287-5300
Abstract  |  PDF  |  HTML  |  How to cite

New cGMP analogues restrain proliferation and migration of melanoma cells

New cGMP analogues restrain proliferation and migration of melanoma cells

https://doi.org/10.18632/oncotarget.23685

Eleonora Vighi, Andreas Rentsch, Philipp Henning, Antonella Comitato, Dorit Hoffmann, Daniela Bertinetti, Evelina Bertolotti, Frank Schwede, Friedrich W. Herberg, Hans-Gottfried Genieser,  and Valeria Marigo
5301-5320
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Hyperglycemia induced testicular damage in type 2 diabetes mellitus rats exhibiting microcirculation impairments associated with vascular endothelial growth factor decreased via PI3K/Akt pathway

Hyperglycemia induced testicular damage in type 2 diabetes mellitus rats exhibiting microcirculation impairments associated with vascular endothelial growth factor decreased via PI3K/Akt pathway

https://doi.org/10.18632/oncotarget.23915

Lingli Long, Han Qiu, Bing Cai, Ningning Chen, Xiaofang Lu, Shuhui Zheng, Xiaoxin Ye,  and Yubin Li
5321-5336
Abstract  |  PDF  |  HTML  |  How to cite

Dual trigger of triptorelin and HCG optimizes clinical outcome for high ovarian responder in GnRH-antagonist protocols

Dual trigger of triptorelin and HCG optimizes clinical outcome for high ovarian responder in GnRH-antagonist protocols

https://doi.org/10.18632/oncotarget.23916

Saijiao Li, Danni Zhou, Tailang Yin, Wangming Xu, Qingzhen Xie, Dan Cheng,  and Jing Yang
5337-5343
Abstract  |  PDF  |  HTML  |  How to cite

Expression and function of nuclear receptor coactivator 4 isoforms in transformed endometriotic and malignant ovarian cells

Expression and function of nuclear receptor coactivator 4 isoforms in transformed endometriotic and malignant ovarian cells

https://doi.org/10.18632/oncotarget.23747

Stephanie Rockfield, Idhaliz Flores,  and Meera Nanjundan
5344-5367
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Meta-Analysis

Dipyridamole decreases dialysis risk and improves survival in patients with pre-dialysis advanced chronic kidney disease

Dipyridamole decreases dialysis risk and improves survival in patients with pre-dialysis advanced chronic kidney disease

https://doi.org/10.18632/oncotarget.19850

Ko-Lin Kuo, Szu-Chun Hung, Wei-Cheng Tseng, Jia-Sin Liu, Ming-Huang Lin, Chih-Cheng Hsu,  and Der-Cherng Tarng
5368-5377
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Diagnostic value of WIF1 methylation for colorectal cancer: a meta-analysis

Diagnostic value of WIF1 methylation for colorectal cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.23870

Haochang Hu, Bin Li, Cong Zhou, Xiuru Ying, Min Chen, Tianyi Huang, Yuehong Chen, Huihui Ji, Ranran Pan, Tiangong Wang, Danjie Jiang, Yanfei Chen, Yong Yang,  and Shiwei Duan
5378-5386
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Prevalence of celiac disease in patients with Down syndrome: a meta-analysis

Prevalence of celiac disease in patients with Down syndrome: a meta-analysis

https://doi.org/10.18632/oncotarget.23624

Yang Du, Ling-Fei Shan, Zong-Ze Cao, Jin-Chao Feng,  and Yong Cheng
5387-5396
Abstract  |  PDF  |  HTML  |  How to cite

Diagnostic value of circulating microRNAs for liver cirrhosis: a meta-analysis

Diagnostic value of circulating microRNAs for liver cirrhosis: a meta-analysis

https://doi.org/10.18632/oncotarget.23332

Liwei Guo, Weiyan Li, Liyang Hu, Huanhuan Zhou, Lei Zheng, Lifei Yu,  and Weifeng Liang
5397-5405
Abstract  |  PDF  |  HTML  |  How to cite

A meta-analysis of the lymphatic microvessel density and survival in gastric cancer with 1809 cases

A meta-analysis of the lymphatic microvessel density and survival in gastric cancer with 1809 cases

https://doi.org/10.18632/oncotarget.23526

Liang Liang, Wen-Ting Huang, Rong-Quan He, Hai-Wei Liang, Chun-Qin Huang, Hong Zhou, Fang-Lin Wei, Sheng-Sheng Zhou, Zhi-Gang Peng, Gang Chen, Jun-Qiang Chen,  and Xin-Gan Qin
5406-5415
Abstract  |  PDF  |  HTML  |  How to cite

Clinical Research Papers

Effect of metformin on kidney function in patients with type 2 diabetes mellitus and moderate chronic kidney disease

Effect of metformin on kidney function in patients with type 2 diabetes mellitus and moderate chronic kidney disease

https://doi.org/10.18632/oncotarget.23387

Wei-Hao Hsu, Pi-Jung Hsiao, Pi-Chen Lin, Szu-Chia Chen, Mei-Yueh Lee,  and Shyi-Jang Shin
5416-5423
Abstract  |  PDF  |  HTML  |  How to cite

Experiment research of focused ultrasound combined with drug and microbubble for treatment of central nervous system leukemia

Experiment research of focused ultrasound combined with drug and microbubble for treatment of central nervous system leukemia

https://doi.org/10.18632/oncotarget.23521

Xiao-Ping Xi, Yu-Jin Zong, Yan-Hong Ji, Bing Wang,  and Hua-Sheng Liu
5424-5434
Abstract  |  PDF  |  HTML  |  How to cite

Effect of postoperative systemic therapy on pulmonary adenocarcinoma with unexpected pleural spread detected during thoracotomy or thoracoscopy

Effect of postoperative systemic therapy on pulmonary adenocarcinoma with unexpected pleural spread detected during thoracotomy or thoracoscopy

https://doi.org/10.18632/oncotarget.23686

Chi-Lu Chiang, Lei-Chi Wang, Hsiang-Ling Ho, Chun-Ming Tsai, Yi-Chen Yeh, Wen-Hu Hsu, Teh-Ying Chou, Chao-Hua Chiu,  and Yu-Chung Wu
5435-5444
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Reviews

MicroRNA expression and activity in T-cell acute lymphoblastic leukemia

MicroRNA expression and activity in T-cell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.23539

Fang Ye
5445-5458
Abstract  |  PDF  |  HTML  |  How to cite

Targeted drugs for systemic therapy of lung cancer with brain metastases

Targeted drugs for systemic therapy of lung cancer with brain metastases

https://doi.org/10.18632/oncotarget.23616

Ya-Wen Sun, Jian Xu, Jun Zhou,  and Wen-Juan Liu
5459-5472
Abstract  |  PDF  |  HTML  |  How to cite

miRNA dysregulation and the risk of metastasis and invasion in papillary thyroid cancer: a systematic review and meta-analysis

miRNA dysregulation and the risk of metastasis and invasion in papillary thyroid cancer: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.16681

Tiantian Wang, Hao Xu, Ming Qi, Xingsong Tian,  and Xingsong Tian
5473-5479
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Decorin is a pivotal effector in the extracellular matrix and tumour microenvironment

Decorin is a pivotal effector in the extracellular matrix and tumour microenvironment

https://doi.org/10.18632/oncotarget.23869

Wen Zhang, Yan Ge, Qian Cheng, Qi Zhang, Lin Fang,  and Junnian Zheng
5480-5491
Abstract  |  PDF  |  HTML  |  How to cite

Exon 3 mutations of CTNNB1 drive tumorigenesis: a review

Exon 3 mutations of CTNNB1 drive tumorigenesis: a review

https://doi.org/10.18632/oncotarget.23695

Chao Gao, Yingmei Wang, Russell Broaddus, Longhao Sun, Fengxia Xue,  and Wei Zhang
5492-5508
Abstract  |  PDF  |  HTML  |  How to cite

Case Reports

Successful retreatment with sofosbuvir plus ledipasvir for cirrhotic patients with hepatitis C virus genotype 1b, who discontinued the prior treatment with asunaprevir plus daclatasvir: A case series and review of the literature

Successful retreatment with sofosbuvir plus ledipasvir for cirrhotic patients with hepatitis C virus genotype 1b, who discontinued the prior treatment with asunaprevir plus daclatasvir: A case series and review of the literature

https://doi.org/10.18632/oncotarget.23768

Yuki Haga, Tatsuo Kanda, Shin Yasui, Masato Nakamura, Yoshihiko Ooka, Koji Takahashi, Shuang Wu, Shingo Nakamoto, Makoto Arai, Tetsuhiro Chiba, Hitoshi Maruyama, Osamu Yokosuka, Nobuo Takada, Mitsuhiko Moriyama, Fumio Imazeki,  and Naoya Kato
5509-5513
Abstract  |  PDF  |  HTML  |  How to cite

Corrections

Correction: Diagnostic performance enhancement of pancreatic cancer using proteomic multimarker panel

Correction: Diagnostic performance enhancement of pancreatic cancer using proteomic multimarker panel

https://doi.org/10.18632/oncotarget.24175

Jiyoung Park, Yonghwan Choi, Junghyun Namkung, Sung Gon Yi, Hyunsoo Kim, Jiyoung Yu, Yongkang Kim, Min-Seok Kwon, Wooil Kwon, Do-Youn Oh, Sun-Whe Kim, Seung-Yong Jeong, Wonshik Han, Kyu Eun Lee, Jin Seok Heo, Joon Oh Park, Joo Kyung Park, Song Cheol Kim, Chang Moo Kang, Woo Jin Lee, Seungyeoun Lee, Sangjo Han, Taesung Park, Jin-Young Jang,  and Youngsoo Kim
5514-5514
Correction  |  PDF  |  How to cite


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