
About The Cover
The cover for issue 33 of Oncotarget features Figure 7A, "Anti-STn ADCs impede OvCa xenograft growth in vivo and target STn+ cells," from Starbuck, et al.
Table of Contents
Research Papers
SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia
SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia |
https://doi.org/10.18632/oncotarget.25089 Jolanda Sarno, Angela M. Savino, Chiara Buracchi, Chiara Palmi, Stefania Pinto, Cristina Bugarin, Astraea Jager, Silvia Bresolin, Ruth C. Barber, Daniela Silvestri, Shai Israeli, Martin J.S. Dyer, Giovanni Cazzaniga, Garry P. Nolan, Andrea Biondi, Kara L. Davis, and Giuseppe Gaipa |
22872-22885 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Analysis of KIT gene mutations in patients with melanoma of the head and neck mucosa: a retrospective clinical report
Analysis of KIT gene mutations in patients with melanoma of the head and neck mucosa: a retrospective clinical report |
https://doi.org/10.18632/oncotarget.25094 Ullyanov Bezerra Toscano de Mendonça, Claudio Roberto Cernea, Leandro Luongo Matos, and Roberto Rego Monteiro de Araujo Lima |
22886-22894 |
Abstract | PDF | HTML | How to cite |
Comprehensive molecular analysis based on somatic copy number alterations in intramucosal colorectal neoplasias and early invasive colorectal cancers
Comprehensive molecular analysis based on somatic copy number alterations in intramucosal colorectal neoplasias and early invasive colorectal cancers |
https://doi.org/10.18632/oncotarget.25112 Tamotsu Sugai, Makoto Eizuka, Wataru Habano, Yasuko Fujita, Ayaka Sato, Ryo Sugimoto, Kouki Otsuka, Eiichiro Yamamoto, Takayuki Matsumoto, and Hiromu Suzuki |
22895-22906 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Involvement of SNPs in miR-3117 and miR-3689d2 in childhood acute lymphoblastic leukemia risk
Involvement of SNPs in miR-3117 and miR-3689d2 in childhood acute lymphoblastic leukemia risk |
https://doi.org/10.18632/oncotarget.25144 Angela Gutierrez-Camino, Idoia Martin-Guerrero, Vita Dolza, Janez Jazbec, Ana Carbone-Bañeres, Nagore Garcia de Andoin, Ana Sastre, Itziar Astigarraga, Aurora Navajas, and Africa Garcia-Orad |
22907-22914 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
YdjC chitooligosaccharide deacetylase homolog induces keratin reorganization in lung cancer cells: involvement of interaction between YDJC and CDC16
YdjC chitooligosaccharide deacetylase homolog induces keratin reorganization in lung cancer cells: involvement of interaction between YDJC and CDC16 |
https://doi.org/10.18632/oncotarget.25145 Eun Ji Kim, Mi Kyung Park, Hyun Jung Byun, Gyeoung Jin Kang, Lu Yu, Hyun Ji Kim, Jae Gal Shim, Ho Lee, and Chang Hoon Lee |
22915-22928 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Disturbed alternative splicing of FIR (PUF60) directed cyclin E overexpression in esophageal cancers
Disturbed alternative splicing of FIR (PUF60) directed cyclin E overexpression in esophageal cancers |
https://doi.org/10.18632/oncotarget.25149 Yukiko Ogura, Tyuji Hoshino, Nobuko Tanaka, Guzhanuer Ailiken, Sohei Kobayashi, Kouichi Kitamura, Bahityar Rahmutulla, Masayuki Kano, Kentarou Murakami, Yasunori Akutsu, Fumio Nomura, Sakae Itoga, Hisahiro Matsubara, and Kazuyuki Matsushita |
22929-22944 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Using antibody directed phototherapy to target oesophageal adenocarcinoma with heterogeneous HER2 expression
Using antibody directed phototherapy to target oesophageal adenocarcinoma with heterogeneous HER2 expression |
https://doi.org/10.18632/oncotarget.25159 Hayley Pye, Mohammed Adil Butt, Laura Funnell, Halla W. Reinert, Ignazio Puccio, Saif U. Rehman Khan, Savvas Saouros, Jared S. Marklew, Ioanna Stamati, Maryam Qurashi, Rehan Haidry, Vinay Sehgal, Dahmane Oukrif, Michael Gandy, Hayley C. Whitaker, Manuel Rodriguez-Justo, Marco Novelli, Rifat Hamoudi, Gokhan Yahioglu, Mahendra P. Deonarain, and Laurence B. Lovat |
22945-22959 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Preclinical evaluation of a GFRA1 targeted antibody-drug conjugate in breast cancer
Preclinical evaluation of a GFRA1 targeted antibody-drug conjugate in breast cancer |
https://doi.org/10.18632/oncotarget.25160 Emily E. Bosco, R. James Christie, Rosa Carrasco, Darrin Sabol, Jiping Zha, Karma DaCosta, Lee Brown, Maureen Kennedy, John Meekin, Sandrina Phipps, Joanne Ayriss, Qun Du, Binyam Bezabeh, Partha Chowdhury, Shannon Breen, Cui Chen, Molly Reed, MaryJane Hinrichs, Haihong Zhong, Zhan Xiao, Rakesh Dixit, Ronald Herbst, and David A. Tice |
22960-22975 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Carbon ion radiotherapy for inoperable pediatric osteosarcoma
Carbon ion radiotherapy for inoperable pediatric osteosarcoma |
https://doi.org/10.18632/oncotarget.25165 Osama Mohamad, Reiko Imai, Tadashi Kamada, Yuki Nitta, Nobuhito Araki, and the Working Group for Bone and Soft Tissue Sarcoma |
22976-22985 |
Abstract | PDF | HTML | How to cite |
Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition
Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition |
https://doi.org/10.18632/oncotarget.25184 Takaaki Oba, and Ken-Ichi Ito |
22986-23002 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Bromodomain protein BRD4 inhibitor JQ1 regulates potential prognostic molecules in advanced renal cell carcinoma
Bromodomain protein BRD4 inhibitor JQ1 regulates potential prognostic molecules in advanced renal cell carcinoma |
https://doi.org/10.18632/oncotarget.25190 Takashi Sakaguchi, Hirofumi Yoshino, Satoshi Sugita, Kazutaka Miyamoto, Masaya Yonemori, Yoichi Osako, Makiko Meguro-Horike, Shin-ichi Horike, Masayuki Nakagawa, and Hideki Enokida |
23003-23017 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Aberrant ATRX protein expression is associated with poor overall survival in NF1-MPNST
Aberrant ATRX protein expression is associated with poor overall survival in NF1-MPNST |
https://doi.org/10.18632/oncotarget.25195 Hsiang-Chih Lu, Vanessa Eulo, Anthony J. Apicelli, Melike Pekmezci, Yu Tao, Jingqin Luo, Angela C. Hirbe, and Sonika Dahiya |
23018-23028 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity
Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity |
https://doi.org/10.18632/oncotarget.25196 Lydia A. Hepburn, Angela McHugh, Kenneth Fernandes, Garry Boag, Charlotte M. Proby, Irene M. Leigh, and Mark K. Saville |
23029-23046 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Risk-stratified surveillance protocol improves cost-effectiveness after radical nephroureterectomy in patients with upper tract urothelial carcinoma
Risk-stratified surveillance protocol improves cost-effectiveness after radical nephroureterectomy in patients with upper tract urothelial carcinoma |
https://doi.org/10.18632/oncotarget.25198 Masaki Momota, Shingo Hatakeyama, Hayato Yamamoto, Hiromichi Iwamura, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Ikuya Iwabuchi, Masaru Ogasawara, Toshiaki Kawaguchi, and Chikara Ohyama |
23047-23057 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Oncodriver inhibition and CD4+ Th1 cytokines cooperate through Stat1 activation to induce tumor senescence and apoptosis in HER2+ and triple negative breast cancer: implications for combining immune and targeted therapies
Oncodriver inhibition and CD4+ Th1 cytokines cooperate through Stat1 activation to induce tumor senescence and apoptosis in HER2+ and triple negative breast cancer: implications for combining immune and targeted therapies |
https://doi.org/10.18632/oncotarget.25208 Cinthia Rosemblit, Jashodeep Datta, Lea Lowenfeld, Shuwen Xu, Amrita Basu, Krithika Kodumudi, Doris Wiener, and Brian J. Czerniecki |
23058-23077 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Metabolomics based predictive classifier for early detection of pancreatic ductal adenocarcinoma
Metabolomics based predictive classifier for early detection of pancreatic ductal adenocarcinoma |
https://doi.org/10.18632/oncotarget.25212 Keith Unger, Khyati Y. Mehta, Prabhjit Kaur, Yiwen Wang, Smrithi S. Menon, Shreyans K. Jain, Rose A. Moonjelly, Shubhankar Suman, Kamal Datta, Rajbir Singh, Paul Fogel, and Amrita K. Cheema |
23078-23090 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Abundance of TRAIL attenuated by HIF2α and c-FLIP affects malignancy in renal cell carcinomas
Abundance of TRAIL attenuated by HIF2α and c-FLIP affects malignancy in renal cell carcinomas |
https://doi.org/10.18632/oncotarget.25214 Takahiro Isono, Tokuhiro Chano, Tetsuya Yoshida, Susumu Kageyama, Akihiro Kawauchi, Junji Yonese, and Takeshi Yuasa |
23091-23101 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
A targeted transforming growth factor-beta (TGF-β) blocker, TTB, inhibits tumor growth and metastasis
A targeted transforming growth factor-beta (TGF-β) blocker, TTB, inhibits tumor growth and metastasis |
https://doi.org/10.18632/oncotarget.24562 Changhua Zhou, Jing Li, Limin Lin, Rui Shu, Bin Dong, Donglin Cao, Qing Li, and Zhong Wang |
23102-23113 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Association of increased primary breast tumor AGR2 with decreased disease-specific survival
Association of increased primary breast tumor AGR2 with decreased disease-specific survival |
https://doi.org/10.18632/oncotarget.25225 Phoebe Ann, Brandon-Luke L. Seagle, Arunima Shilpi, Manoj Kandpal, and Shohreh Shahabi |
23114-23125 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Differential prognostic impact of interleukin-34 mRNA expression and infiltrating immune cell composition in intrinsic breast cancer subtypes
Differential prognostic impact of interleukin-34 mRNA expression and infiltrating immune cell composition in intrinsic breast cancer subtypes |
https://doi.org/10.18632/oncotarget.25226 Karin Zins, Gerwin Heller, Mathias Mayerhofer, Martin Schreiber, and Dietmar Abraham |
23126-23148 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1
SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1 |
https://doi.org/10.18632/oncotarget.25234 Margit Schwartz, Sabine Böckmann, Philipp Borchert, and Burkhard Hinz |
23149-23163 |
Abstract | PDF | HTML | How to cite |
Preoperative tumor size is associated with deep myometrial invasion and lymph node metastases and is a negative prognostic indicator for patients with endometrial carcinoma
Preoperative tumor size is associated with deep myometrial invasion and lymph node metastases and is a negative prognostic indicator for patients with endometrial carcinoma |
https://doi.org/10.18632/oncotarget.25248 Kohei Nakamura, Kentaro Nakayama, Noriyoshi Ishikawa, Toshiko Minamoto, Tomoka Ishibashi, Kaori Ohnishi, Hitomi Yamashita, Ruriko Ono, Hiroki Sasamori, Sultana Razia, Mohammad Mahmud Hossain, Shanta Kamrunnahar, Masako Ishikawa, and Satoru Kyo |
23164-23172 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Gene expression profiling in prognosis of distant recurrence in HR-positive and HER2-negative breast cancer patients
Gene expression profiling in prognosis of distant recurrence in HR-positive and HER2-negative breast cancer patients |
https://doi.org/10.18632/oncotarget.25258 Tzu-Ting Huang, Nicolas Pennarun, Yu-Hao Cheng, Cheng-Fang Horng, Jason Lei, and Skye Hung-Chun Cheng |
23173-23182 |
Abstract | PDF | HTML | How to cite |
RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry
RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry |
https://doi.org/10.18632/oncotarget.25259 Sarita Rani Patnaik, Xun Zhang, Lincoln Biswas, Saeed Akhtar, Xinzhi Zhou, Deva Krupakar Kusuluri, James Reilly, Helen May-Simera, Susan Chalmers, John McCarron, and Xinhua Shu |
23183-23197 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
DGC-specific RHOA mutations maintained cancer cell survival and promoted cell migration via ROCK inactivation
DGC-specific RHOA mutations maintained cancer cell survival and promoted cell migration via ROCK inactivation |
https://doi.org/10.18632/oncotarget.25269 Takashi Nishizawa, Kiyotaka Nakano, Aya Harada, Miwako Kakiuchi, Shin-Ichi Funahashi, Masami Suzuki, Shumpei Ishikawa, and Hiroyuki Aburatani |
23198-23207 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
PKD1 is a potential biomarker and therapeutic target in triple-negative breast cancer
PKD1 is a potential biomarker and therapeutic target in triple-negative breast cancer |
https://doi.org/10.18632/oncotarget.25292 Caroline Spasojevic, Elisabetta Marangoni, Sophie Vacher, Franck Assayag, Didier Meseure, Sophie Château-Joubert, Martine Humbert, Manale Karam, Jean Marc Ricort, Christian Auclair, Marie Regairaz, and Ivan Bièche |
23208-23219 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
MAP4K4 controlled integrin β1 activation and c-Met endocytosis are associated with invasive behavior of medulloblastoma cells
MAP4K4 controlled integrin β1 activation and c-Met endocytosis are associated with invasive behavior of medulloblastoma cells |
https://doi.org/10.18632/oncotarget.25294 Dimitra Tripolitsioti, Karthiga Santhana Kumar, Anuja Neve, Jessica Migliavacca, Charles Capdeville, Elisabeth J. Rushing, Min Ma, Noriyuki Kijima, Ashish Sharma, Martin Pruschy, Scott McComb, Michael D. Taylor, Michael A. Grotzer, and Martin Baumgartner |
23220-23236 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Chloride intracellular channel 1 as a switch among tumor behaviors in human esophageal squamous cell carcinoma
Chloride intracellular channel 1 as a switch among tumor behaviors in human esophageal squamous cell carcinoma |
https://doi.org/10.18632/oncotarget.25296 Toshiyuki Kobayashi, Atsushi Shiozaki, Yoshito Nako, Daisuke Ichikawa, Toshiyuki Kosuga, Katsutoshi Shoda, Tomohiro Arita, Hirotaka Konishi, Shuhei Komatsu, Takeshi Kubota, Hitoshi Fujiwara, Kazuma Okamoto, Mitsuo Kishimoto, Eiichi Konishi, Yoshinori Marunaka, and Eigo Otsuji |
23237-23252 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
miR-34a, miR-424 and miR-513 inhibit MMSET expression to repress endometrial cancer cell invasion and sphere formation
miR-34a, miR-424 and miR-513 inhibit MMSET expression to repress endometrial cancer cell invasion and sphere formation |
https://doi.org/10.18632/oncotarget.25298 Peixin Dong, Ying Xiong, Junming Yue, Sharon J.B. Hanley, and Hidemichi Watari |
23253-23263 |
Abstract | PDF | HTML | How to cite |
Cytokeratin 8/18 protects breast cancer cell lines from TRAIL-induced apoptosis
Cytokeratin 8/18 protects breast cancer cell lines from TRAIL-induced apoptosis |
https://doi.org/10.18632/oncotarget.25297 William P. Bozza, Yaqin Zhang, and Baolin Zhang |
23264-23273 |
Abstract | PDF | HTML | How to cite |
The effects of restricted glycolysis on stem-cell like characteristics of breast cancer cells
The effects of restricted glycolysis on stem-cell like characteristics of breast cancer cells |
https://doi.org/10.18632/oncotarget.25299 Arindam Banerjee, Pardis Arvinrad, Matthew Darley, Stéphanie A. Laversin, Rachel Parker, Matthew J.J. Rose-Zerilli, Paul A. Townsend, Ramsey I. Cutress, Stephen A. Beers, Franchesca D. Houghton, Charles N. Birts, and Jeremy P. Blaydes |
23274-23288 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Treatment of ovarian cancer by targeting the tumor stem cell-associated carbohydrate antigen, Sialyl-Thomsen-nouveau
Treatment of ovarian cancer by targeting the tumor stem cell-associated carbohydrate antigen, Sialyl-Thomsen-nouveau |
https://doi.org/10.18632/oncotarget.25289 Kristen Starbuck, Linah Al-Alem, David A. Eavarone, Silvia Fatima Hernandez, Chiara Bellio, Jillian M. Prendergast, Jenna Stein, Daniel T. Dransfield, Bianca Zarrella, Whitfield B. Growdon, Jeff Behrens, Rosemary Foster, and Bo R. Rueda |
23289-23305 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Reviews
Cancer stem cells of hepatocellular carcinoma
Cancer stem cells of hepatocellular carcinoma |
https://doi.org/10.18632/oncotarget.24623 Kewei Wang, and Dianjun Sun |
23306-23314 |
Abstract | PDF | HTML | How to cite |
Case Reports
A case of ALK-rearranged non–small cell lung cancer that responded to ceritinib after development of resistance to alectinib
A case of ALK-rearranged non–small cell lung cancer that responded to ceritinib after development of resistance to alectinib |
https://doi.org/10.18632/oncotarget.25143 Yosuke Makuuchi, Hidetoshi Hayashi, Koji Haratani, Junko Tanizaki, Kaoru Tanaka, Masayuki Takeda, Kazuko Sakai, Shigeki Shimizu, Akihiko Ito, Kazuto Nishio, and Kazuhiko Nakagawa |
23315-23319 |
Abstract | PDF | HTML | How to cite |
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