IL-21 modulates memory and exhaustion phenotype of T-cells in a fatty acid oxidation-dependent manner

Targeting DYRK1B suppresses the proliferation and migration of liposarcoma cells

Phthalate exposure promotes chemotherapeutic drug resistance in colon cancer cells

Exploring the pathogenesis of canine epilepsy using a systems genetics method and implications for anti-epilepsy drug discovery

EIF3C-enhanced exosome secretion promotes angiogenesis and tumorigenesis of human hepatocellular carcinoma

Targeting of embryonic annexin A2 expressed on ovarian and breast cancer by the novel monoclonal antibody 2448

The single-nucleotide polymorphisms in CHD5 affect the prognosis of patients with hepatocellular carcinoma

Reprogrammed lipid metabolism in bladder cancer with cisplatin resistance

miR-128 inhibits telomerase activity by targeting TERT mRNA

Mitochondrial fission as a driver of stemness in tumor cells: mDIVI1 inhibits mitochondrial function, cell migration and cancer stem cell (CSC) signalling

Neutrophil extracellular traps promote lipopolysaccharide-induced airway inflammation and mucus hypersecretion in mice

Deficiency of protein-L-isoaspartate (D-aspartate) O-methyl-transferase expression under endoplasmic reticulum stress promotes epithelial mesenchymal transition in lung adenocarcinoma

Systemic administration of a TLR7 agonist attenuates regulatory T cells by dendritic cell modification and overcomes resistance to PD-L1 blockade therapy

CD151 promotes cell metastasis via activating TGF-β1/Smad signaling in renal cell carcinoma

Methotrexate sensitizes drug-resistant metastatic melanoma cells to BRAF V600E inhibitors dabrafenib and encorafenib

Colorectal cancer cells require glycogen synthase kinase-3β for sustaining mitosis via translocated promoter region (TPR)-dynein interaction

The metal-nonoate Ni(SalPipNONO) inhibits in vitro tumor growth, invasiveness and angiogenesis

Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPin^® protein MP0250: a preclinical study

Efficacy of different spinal nerve roots for neuromodulation of micturition reflex in rats

Amiodarone promotes cancer cell death through elevated truncated SRSF3 and downregulation of miR-224

Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis

The new allosteric inhibitor asciminib is susceptible to resistance mediated by ABCB1 and ABCG2 overexpression in vitro

Trifluridine/tipiracil overcomes the resistance of human gastric 5-fluorouracil-refractory cells with high thymidylate synthase expression

Therapeutic significance of targeting survivin in cervical cancer and possibility of combination therapy with TRAIL

Gram-negative bacteria facilitate tumor progression through TLR4/IL-33 pathway in patients with non-small-cell lung cancer

CDK8/19 inhibition induces premature G1/S transition and ATR-dependent cell death in prostate cancer cells

Effects of Cetuximab and Erlotinib on the behaviour of cancer stem cells in head and neck squamous cell carcinoma

Increased expression of MNK1b, the spliced isoform of MNK1, predicts poor prognosis and is associated with triple-negative breast cancer

An open label trial of folate receptor-targeted intraoperative molecular imaging to localize pulmonary squamous cell carcinomas

Quantitative mass spectrometry analysis reveals a panel of nine proteins as diagnostic markers for colon adenocarcinomas

CHL1 gene polymorphisms increase lung cancer susceptibility

Molecular profiling of ALDH1⁺ colorectal cancer stem cells reveals preferential activation of MAPK, FAK, and oxidative stress pro-survival signalling pathways

Human tripartite motif protein 52 is required for cell context-dependent proliferation

Leukocyte telomere length throughout the continuum of colorectal carcinogenesis

Adenosine A_2A receptor ligand recognition and signaling is blocked by A_2B receptors

Nuclear myosin/actin-motored contact between homologous chromosomes is initiated by ATM kinase and homology-directed repair proteins at double-strand DNA breaks to suppress chromosome rearrangements

Prolonged in vivo expression and anti-tumor response of DNA-based anti-HER2 antibodies

Protective role of integrin-linked kinase against oxidative stress and in maintenance of genomic integrity

Structural insights into drug development strategy targeting EGFR T790M/C797S

Persistent DNA strand breaks induce a CAF-like phenotype in normal fibroblasts

Correlation of MET gene amplification and TP53 mutation with PD-L1 expression in non-small cell lung cancer

Engineered T lymphocytes eliminate lung metastases in models of pancreatic cancer

Inter-assay precision of clonogenic assays for radiosensitivity in cancer cell line A549

Computational modeling suggests impaired interactions between NKX2.5 and GATA4 in individuals carrying a novel pathogenic D16N NKX2.5 mutation

Characterization of brain tumor initiating cells isolated from an animal model of CNS primitive neuroectodermal tumors

Proline oxidase silencing induces proline-dependent pro-survival pathways in MCF-7 cells

MicroRNA-630 may confer favorable cisplatin-based chemotherapy and clinical outcomes in non-small cell lung cancer by targeting Bcl-2

Artificial neural network approach to predict surgical site infection after free-flap reconstruction in patients receiving surgery for head and neck cancer

Cardiac glycoside bufalin blocks cancer cell growth by inhibition of Aurora A and Aurora B activation via PI3K-Akt pathway

Merestinib (LY2801653) inhibits neurotrophic receptor kinase (NTRK) and suppresses growth of NTRK fusion bearing tumors

Integrated DNA methylation analysis identifies topographical and tumoral biomarkers in pilocytic astrocytomas

Nucleolar stress enhances lytic reactivation of the Kaposi's sarcoma-associated herpesvirus

Bcl-xL as a poor prognostic biomarker and predictor of response to adjuvant chemotherapy specifically in BRAF-mutant stage II and III colon cancer

CTBP1 and metabolic syndrome induce an mRNA and miRNA expression profile critical for breast cancer progression and metastasis

Chemopreventive effects of angiotensin II receptor type 2 agonist on prostate carcinogenesis by the down-regulation of the androgen receptor

A single digital droplet PCR assay to detect multiple KIT exon 11 mutations in tumor and plasma from patients with gastrointestinal stromal tumors

Structural considerations for functional anti-EGFR × anti-CD3 bispecific diabodies in light of domain order and binding affinity

Exosomal microRNA profiling to identify hypoxia-related biomarkers in prostate cancer

Prognostic value of PD-L1 in esophageal squamous cell carcinoma: a meta-analysis

Clinicopathologic and prognostic significance of C-reactive protein/albumin ratio in patients with solid tumors: an updated systemic review and meta-analysis

MiR-486 as an effective biomarker in cancer diagnosis and prognosis: a systematic review and meta-analysis

Association of body mass index with mortality and postoperative survival in renal cell cancer patients, a meta-analysis

Prevalence of non-syndromic orofacial clefts: based on 15,094,978 Chinese perinatal infants

Impact of physical exercise in cancer survivors during and after antineoplastic treatments