VOLUME 9 (2018)
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About The Cover
The cover for issue 1 of Oncotarget features Figure 2, "Radiation-induced alternative splice events in the transcriptome and the translatome," from Wahba, et al.
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Table of Contents
News
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| IDH1 R132H predicts sensitivity to BclxL inhibitionmediated programmed cell death |
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https://doi.org/10.18632/oncotarget.23399
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| 1-2 |
Priority Research Papers
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| Accelerated bottomup drug design platform enables the discovery of novel stearoylCoA desaturase 1 inhibitors for cancer therapy |
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https://doi.org/10.18632/oncotarget.21545
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| 3-20 |
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| cMyb and C/EBPβ regulate OPN and other senescenceassociated secretory phenotype factors |
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https://doi.org/10.18632/oncotarget.22940
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| 21-36 |
Research Papers: Gerotarget (Focus on Aging)
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| PINK1 suppresses alphasynucleininduced neuronal injury: a novel mechanism in protein phosphatase 2A activation |
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https://doi.org/10.18632/oncotarget.21554
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| 37-53 |
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| RCAN1 in the inverse association between Alzheimer’s disease and cancer |
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https://doi.org/10.18632/oncotarget.23094
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| 54-66 |
Research Papers: Immunology
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| Urine antiPLA2R antibody is a novel biomarker of idiopathic membranous nephropathy |
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https://doi.org/10.18632/oncotarget.19859
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| 67-74 |
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| Peptide adjacent to glycosylation sites impacts immunogenicity of glycoconjugate vaccine |
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https://doi.org/10.18632/oncotarget.19944
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| 75-82 |
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| Genomewide comparison of the proteincoding repertoire reveals fast evolution of immunerelated genes in cephalochordates and Osteichthyes superclass |
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https://doi.org/10.18632/oncotarget.22749
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| 83-95 |
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| Quantitative assessment of HLADQ gene polymorphisms with the development of hepatitis B virus infection clearance liver cirrhosis and hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.22941
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| 96-109 |
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| Impaired autophagic flux and its related inflammation in patients with adultonset Still’s disease |
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https://doi.org/10.18632/oncotarget.23098
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| 110-121 |
Research Papers: Chromosome
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| Genetic identification and molecular modeling characterization reveal a novel PROM1 mutation in Stargardt4like macular dystrophy |
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https://doi.org/10.18632/oncotarget.22343
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| 122-141 |
Research Papers
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| The prognostic significance of nuclear expression of PHF2 and C/EBPα in clear cell renal cell carcinoma with consideration of adipogenic metabolic evolution |
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https://doi.org/10.18632/oncotarget.19949
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| 142-151 |
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| Deguelin suppresses angiogenesis in human hepatocellular carcinoma by targeting HGFcMet pathway |
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https://doi.org/10.18632/oncotarget.22077
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| 152-166 |
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| CUNR scoring system for the prediction of lateral lymph node metastasis in papillary thyroid carcinoma |
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https://doi.org/10.18632/oncotarget.22772
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| 167-177 |
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| Human DKK1 and human HSP70 fusion DNA vaccine induces an effective antitumor efficacy in murine multiple myeloma |
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https://doi.org/10.18632/oncotarget.23352
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| 178-191 |
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| SOX9PDK1 axis is essential for glioma stem cell selfrenewal and temozolomide resistance |
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https://doi.org/10.18632/oncotarget.22773
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| 192-204 |
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| A method of respiratory phase optimization for better dose sparing of organs at risks: A validation study in patients with lung cancer |
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https://doi.org/10.18632/oncotarget.23353
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| 205-216 |
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| Squamous differentiation in pT1 bladder urothelial carcinoma predicts poor response for intravesical chemotherapy |
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https://doi.org/10.18632/oncotarget.18563
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| 217-223 |
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| Alcohol and hepatitis virusdysregulated lncRNAs as potential biomarkers for hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.22921
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| 224-235 |
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| Altered tolllike receptor expression and function in HPVassociated oropharyngeal carcinoma |
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https://doi.org/10.18632/oncotarget.18959
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| 236-248 |
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| Threedimensional tumor model mimics stromal – breast cancer cells signaling |
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https://doi.org/10.18632/oncotarget.22922
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| 249-267 |
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| Docking of THPDTPI: to explore Pselectin as a common target of antitumor antithrombotic and antiinflammatory agent |
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https://doi.org/10.18632/oncotarget.19374
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| 268-281 |
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| Efficient inhibition of cervical cancer by dual drugs loaded in biodegradable thermosensitive hydrogel composites |
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https://doi.org/10.18632/oncotarget.22965
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| 282-292 |
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| Extracellular signal regulated kinase 5 and inflammasome in progression of mesothelioma |
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https://doi.org/10.18632/oncotarget.22968
|
| 293-305 |
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| Prognostic significance of Ecadherin and ZEB1 expression in intraductal papillary mucinous neoplasm |
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https://doi.org/10.18632/oncotarget.23012
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| 306-320 |
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| MicroRNA761 promotes the sensitivity of colorectal cancer cells to 5Fluorouracil through targeting FOXM1 |
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https://doi.org/10.18632/oncotarget.20109
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| 321-331 |
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| Low dose radiation prevents doxorubicininduced cardiotoxicity |
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https://doi.org/10.18632/oncotarget.23013
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| 332-345 |
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| Preclinical efficacy and biological effects of the oral proteasome inhibitor ixazomib in diffuse large Bcell lymphoma |
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https://doi.org/10.18632/oncotarget.20378
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| 346-360 |
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| The inhibitory activity of gallic acid against DNA methylation: application of gallic acid on epigenetic therapy of human cancers |
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https://doi.org/10.18632/oncotarget.23015
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| 361-374 |
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| Iodine stimulates estrogen receptor singling and its systemic level is increased in surgical patients due to topical absorption |
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https://doi.org/10.18632/oncotarget.20633
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| 375-384 |
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| A prognostic score model to determine which breast cancer patients with 1–3 positive lymph nodes after modified radical mastectomy should receive radiotherapy |
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https://doi.org/10.18632/oncotarget.21531
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| 385-393 |
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| MnTBAP therapy attenuates the downregulation of sodium transporters in obstructive kidney disease |
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https://doi.org/10.18632/oncotarget.23037
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| 394-403 |
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| HBXIP activates the PPARδ/NFκB feedback loop resulting in cell proliferation |
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https://doi.org/10.18632/oncotarget.23057
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| 404-417 |
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| 125Dihydroxyvitamin D3 inhibits the proliferation of rat mesangial cells induced by high glucose via DDIT4 |
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https://doi.org/10.18632/oncotarget.23063
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| 418-427 |
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| Comparison of clinical and survival characteristics between prostate cancer patients of PSAbased screening and clinical diagnosis in China |
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https://doi.org/10.18632/oncotarget.20787
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| 428-441 |
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| Utilizing glycine Nmethyltransferasegene knockout mice as a model for identification of missing proteins in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.23064
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| 442-452 |
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| Transcriptome evolution from breast epithelial cells to basallike tumors |
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https://doi.org/10.18632/oncotarget.23065
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| 453-463 |
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| Exome sequencing reveals aberrant signalling pathways as hallmark of treatmentnaive anal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.23066
|
| 464-476 |
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| Homing of endogenous bone marrow mesenchymal stem cells to rat infarcted myocardium via ultrasoundmediated recombinant SDF1α adenovirus in microbubbles |
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https://doi.org/10.18632/oncotarget.23068
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| 477-487 |
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| Prognostic value of quantitative ctDNA levels in non small cell lung cancer patients |
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https://doi.org/10.18632/oncotarget.22470
|
| 488-494 |
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| In vitro and in vivo antileukemic effects of cladoloside C2 are mediated by activation of Fas/ceramide synthase 6/p38 kinase/ cJun NH2terminal kinase/caspase8 |
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https://doi.org/10.18632/oncotarget.23069
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| 495-511 |
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| HDAC inhibitor PAC320 induces G2/M cell cycle arrest and apoptosis in human prostate cancer |
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https://doi.org/10.18632/oncotarget.23070
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| 512-523 |
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| Allogeneic hematopoietic stem cell transplantation for relapsed acute myeloid leukemia in ETO positive with reducedintensity conditioning |
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https://doi.org/10.18632/oncotarget.22612
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| 524-538 |
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| Loss of epitheliumspecific GPx2 results in aberrant cell fate decisions during intestinal differentiation |
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https://doi.org/10.18632/oncotarget.22640
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| 539-552 |
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| OTUD7B upregulation predicts a poor response to paclitaxel in patients with triplenegative breast cancer |
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https://doi.org/10.18632/oncotarget.23074
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| 553-565 |
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| Pathwayfocused PCR array profiling of CAL27 cell with overexpressed ZNF750 |
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https://doi.org/10.18632/oncotarget.23075
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| 566-575 |
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| Liver X receptors agonist promotes differentiation of rat bone marrow derived mesenchymal stem cells into dopaminergic neuronlike cells |
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https://doi.org/10.18632/oncotarget.23076
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| 576-590 |
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| Nicotineenhanced stemness and epithelialmesenchymal transition of human umbilical cord mesenchymal stem cells promote tumor formation and growth in nude mice |
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https://doi.org/10.18632/oncotarget.22712
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| 591-606 |
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| Expression of ANO1/DOG1 is associated with shorter survival and progression of breast carcinomas |
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https://doi.org/10.18632/oncotarget.23078
|
| 607-621 |
|
| Development of suspension cell culture model to mimic circulating tumor cells |
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https://doi.org/10.18632/oncotarget.23079
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| 622-640 |
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| PDL1 CD274 and PDL2 PDCD1LG2 promoter methylation is associated with HPV infection and transcriptional repression in head and neck squamous cell carcinomas |
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https://doi.org/10.18632/oncotarget.23080
|
| 641-650 |
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| Progesterone inhibits contraction and increases TREK1 potassium channel expression in late pregnant rat uterus |
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https://doi.org/10.18632/oncotarget.23084
|
| 651-661 |
|
| Clinical validation of serum endocan ESM1 as a potential biomarker in patients with renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.23087
|
| 662-667 |
|
| CMYC and BCL2 mediate YAPregulated tumorigenesis in OSCC |
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https://doi.org/10.18632/oncotarget.23089
|
| 668-679 |
|
| PGK1 and GRP78 overexpression correlates with clinical significance and poor prognosis in Chinese endometrial cancer patients |
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https://doi.org/10.18632/oncotarget.23090
|
| 680-690 |
|
| Radiationinduced alternative transcripts as detected in total and polysomebound mRNA |
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https://doi.org/10.18632/oncotarget.21672
|
| 691-705 |
|
| The dual PI3K/mTOR inhibitor dactolisib elicits antitumor activity in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.23091
|
| 706-717 |
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| Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2 |
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https://doi.org/10.18632/oncotarget.22002
|
| 718-725 |
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| Cooperation between ZEB2 and Sp1 promotes cancer cell survival and angiogenesis during metastasis through induction of survivin and VEGF |
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https://doi.org/10.18632/oncotarget.23139
|
| 726-742 |
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| Organic cation transporter 3 mediates cisplatin and copper crossresistance in hepatoma cells |
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https://doi.org/10.18632/oncotarget.23142
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| 743-754 |
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| Jazf1 promotes prostate cancer progression by activating JNK/Slug |
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https://doi.org/10.18632/oncotarget.23146
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| 755-765 |
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| Phase II study of rituximab given in conjunction with standard chemotherapy in primary central nervous system lymphoma PCNSL: a trial of the ECOGACRIN cancer research group E1F05 |
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https://doi.org/10.18632/oncotarget.22332
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| 766-773 |
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| Thyroid cancer risk in the Swedish AMORIS study: the role of inflammatory biomarkers in serum |
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https://doi.org/10.18632/oncotarget.22891
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| 774-782 |
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| Downregulation of long noncoding RNA ESCCAL_1 inhibits tumor growth of esophageal squamous cell carcinoma in a xenograft mouse model |
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https://doi.org/10.18632/oncotarget.23153
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| 783-790 |
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| Folate receptorα targeted nearinfrared fluorescence imaging in highrisk endometrial cancer patients: a tissue microarray and clinical feasibility study |
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https://doi.org/10.18632/oncotarget.23155
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| 791-801 |
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| Propranolol enhanced the antitumor effect of sunitinib by inhibiting proliferation and inducing G0/G1/S phase arrest in malignant melanoma |
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https://doi.org/10.18632/oncotarget.22696
|
| 802-811 |
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| Efficient leukocyte depletion by a novel microfluidic platform enables the molecular detection and characterization of circulating tumor cells |
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https://doi.org/10.18632/oncotarget.22549
|
| 812-823 |
|
| Frizzled10 and cancer progression: Is it a new prognostic marker |
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https://doi.org/10.18632/oncotarget.23159
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| 824-830 |
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| Recombinant rabies virus with the glycoprotein fused with a DCbinding peptide is an efficacious rabies vaccine |
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https://doi.org/10.18632/oncotarget.23160
|
| 831-841 |
|
| FoxM1 is a promising candidate target in the treatment of breast cancer |
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https://doi.org/10.18632/oncotarget.23182
|
| 842-852 |
|
| Gli is activated and promotes epithelialmesenchymal transition in human esophageal adenocarcinoma |
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https://doi.org/10.18632/oncotarget.22856
|
| 853-865 |
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| Xanthohumol prevents dextran sulfate sodiuminduced colitis via inhibition of IKKβ/NFκB signaling in mice |
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https://doi.org/10.18632/oncotarget.23183
|
| 866-880 |
|
| Genetic variation in CDH13 gene was associated with nonsmall cell lung cancer NSCLC: A populationbased casecontrol study |
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https://doi.org/10.18632/oncotarget.22971
|
| 881-891 |
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| Direct bilirubin levels are prognostic in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.23184
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| 892-900 |
|
| Baicalin hydrate inhibits cancer progression in nasopharyngeal carcinoma by affecting genome instability and splicing |
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https://doi.org/10.18632/oncotarget.22868
|
| 901-914 |
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| Recombinant methioninase rMETase is an effective therapeutic for BRAFV600Enegative as well as positive melanoma in patientderived orthotopic xenograft PDOX mouse models |
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https://doi.org/10.18632/oncotarget.23185
|
| 915-923 |
|
| Discovery of a FLT3 inhibitor LDD1937 as an antileukemic agent for acute myeloid leukemia |
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https://doi.org/10.18632/oncotarget.23221
|
| 924-936 |
|
| Molecular mechanisms of cardioprotective effects mediated by transplanted cardiac ckit+ cells through the activation of an inflammatory hypoxiadependent reparative response |
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https://doi.org/10.18632/oncotarget.22946
|
| 937-957 |
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| Association of DNA repair gene polymorphisms with the risk of radiation pneumonitis in lung cancer patients |
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https://doi.org/10.18632/oncotarget.22982
|
| 958-968 |
|
| Genomic landscape of colitisassociated cancer indicates the impact of chronic inflammation and its stratification by mutations in the Wnt signaling |
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https://doi.org/10.18632/oncotarget.22867
|
| 969-981 |
|
| Prostaglandin receptor EP3 regulates cell proliferation and migration with impact on survival of endometrial cancer patients |
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https://doi.org/10.18632/oncotarget.23140
|
| 982-994 |
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| Mitochondrial dysfunction activates lysosomaldependent mitophagy selectively in cancer cells |
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https://doi.org/10.18632/oncotarget.23171
|
| 995-1011 |
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| Splice variants of the endonucleases XPF and XPG contain residual DNA repair capabilities and could be a valuable tool for personalized medicine |
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https://doi.org/10.18632/oncotarget.23105
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| 1012-1027 |
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| SNHG16/miR1405p axis promotes esophagus cancer cell proliferation migration and EMT formation through regulating ZEB1 |
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https://doi.org/10.18632/oncotarget.23178
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| 1028-1040 |
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| Phosphorylation of caspase9 at Thr125 directs paclitaxel resistance in ovarian cancer |
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https://doi.org/10.18632/oncotarget.23133
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| 1041-1047 |
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| Long noncoding RNA GAS5 and ZFAS1 are prognostic markers involved in translation targeted by miR940 in prostate cancer |
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https://doi.org/10.18632/oncotarget.23254
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| 1048-1062 |
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| Identification of human ageassociated gene coexpressions in functional modules using liquid association |
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https://doi.org/10.18632/oncotarget.23148
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| 1063-1074 |
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| MiR27a as a predictor for the activation of hepatic stellate cells and hepatitis B virusinduced liver cirrhosis |
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https://doi.org/10.18632/oncotarget.23262
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| 1075-1090 |
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| CONCORD biomarker prediction for novel drug introduction to different cancer types |
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https://doi.org/10.18632/oncotarget.23124
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| 1091-1106 |
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| Elevated transgelin/TNS1 expression is a potential biomarker in human colorectal cancer |
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https://doi.org/10.18632/oncotarget.23275
|
| 1107-1113 |
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| Changes in metabolism affect expression of ABC transporters through ERK5 and depending on p53 status |
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https://doi.org/10.18632/oncotarget.23305
|
| 1114-1129 |
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| Mechanism of action and efficacy of LY2109761a TGFβ receptor inhibitor targeting tumor microenvironment in liver cancer after TACE |
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https://doi.org/10.18632/oncotarget.23193
|
| 1130-1142 |
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| CCAR2 negatively regulates IL8 production in cervical cancer cells |
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https://doi.org/10.18632/oncotarget.23199
|
| 1143-1155 |
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| Downregulation of long noncoding RNA LET predicts poor prognosis and increases Notch signaling in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.23452
|
| 1156-1168 |
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| Estrogen/ERα signaling axis participates in osteoblast maturation via upregulating chromosomal and mitochondrial complex gene expressions |
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https://doi.org/10.18632/oncotarget.23453
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| 1169-1186 |
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| Exosomes released by metabotropic glutamate receptor 1 GRM1 expressing melanoma cells increase cell migration and invasiveness |
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https://doi.org/10.18632/oncotarget.23455
|
| 1187-1199 |
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| No differences in brain microstructure between young KIBRAC carriers and noncarriers |
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https://doi.org/10.18632/oncotarget.23348
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| 1200-1209 |
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| KSHV LANA upregulates the expression of epidermal growth factor like domain 7 to promote angiogenesis |
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https://doi.org/10.18632/oncotarget.23456
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| 1210-1228 |
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| Molecular regulation of ERK5 in development of diabetic retinopathy |
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https://doi.org/10.18632/oncotarget.23392
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| 1229-1236 |
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| High mobility group protein A2 overexpression indicates poor prognosis for cancer patients: a metaanalysis |
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https://doi.org/10.18632/oncotarget.23085
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| 1237-1247 |
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| Chinese C allele carriers of the ERCC5 rs1047768 polymorphism are more sensitive to platinumbased chemotherapy: a metaanalysis |
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https://doi.org/10.18632/oncotarget.18981
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| 1248-1256 |
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| The prognostic value of NRF2 in solid tumor patients: a metaanalysis |
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https://doi.org/10.18632/oncotarget.19838
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| 1257-1265 |
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| Serum levels of adipokines and cytokines in psoriasis patients: a systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.22260
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| 1266-1278 |
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| Prognostic and clinicopathological significance of microRNA494 overexpression in cancers: a metaanalysis |
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https://doi.org/10.18632/oncotarget.22633
|
| 1279-1290 |
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| Association between hypertensive disorders of pregnancy and risk of autism in offspring: a systematic review and metaanalysis of observational studies |
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https://doi.org/10.18632/oncotarget.23030
|
| 1291-1301 |
Clinical Research Papers
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| TNFR/TNFα signaling pathway regulates apoptosis of alveolar macrophages in coal workers' pneumoconiosis |
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https://doi.org/10.18632/oncotarget.18921
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| 1302-1310 |
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| Midarm muscle circumference as a substantial factor against mortality among people with elevated gamma gaps |
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https://doi.org/10.18632/oncotarget.19372
|
| 1311-1325 |
Reviews
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| 3D modeling of cancer stem cell niche |
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https://doi.org/10.18632/oncotarget.19847
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| 1326-1345 |
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| LGR5 and LGR6 in stem cell biology and ovarian cancer |
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https://doi.org/10.18632/oncotarget.20178
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| 1346-1355 |
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| Equine infectious anemia virus in China |
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https://doi.org/10.18632/oncotarget.20381
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| 1356-1364 |
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| Exploring the molecular aspects associated with testicular germ cell tumors: a review |
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https://doi.org/10.18632/oncotarget.22373
|
| 1365-1379 |
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| Drug resistance related to aberrant glycosylation in colorectal cancer |
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https://doi.org/10.18632/oncotarget.22377
|
| 1380-1402 |
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| Current research on head and neck cancerassociated long noncoding RNAs |
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https://doi.org/10.18632/oncotarget.22608
|
| 1403-1425 |
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| LncRNAs regulate cancer metastasis via binding to functional proteins |
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https://doi.org/10.18632/oncotarget.22840
|
| 1426-1443 |
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| Circular RNAs: clinical relevance in cancer |
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https://doi.org/10.18632/oncotarget.22846
|
| 1444-1460 |
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| Troponin through the lookingglass: emerging roles beyond regulation of striated muscle contraction |
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https://doi.org/10.18632/oncotarget.22879
|
| 1461-1482 |
|
| Protein dysregulation in graft versus host disease |
|
https://doi.org/10.18632/oncotarget.23276
|
| 1483-1491 |
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