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About The Cover

The cover for issue 53 of Oncotarget features Figure 8, "Schematic diagram of the mechanism of TC45 nuclear translocation in keratinocytes following UVB irradiation," from Kim, et al.

Table of Contents

Editorial

Replication stress in colorectal cancer stem cells

https://doi.org/10.18632/oncotarget.18045

Gwenola Manic, Ruggero De Maria, and Ilio Vitale
90606-90607
Abstract  |  PDF  |  How to cite

Molecular insights into desmoid tumors

https://doi.org/10.18632/oncotarget.21293

Nam Bui, and Shivaani Kummar
90608-90609
Abstract  |  PDF  |  How to cite

Circulating tumour DNA analysis in multiple myeloma

https://doi.org/10.18632/oncotarget.21595

Sridurga Mithraprabhu, and Andrew Spencer
90610-90611
Abstract  |  PDF  |  How to cite

Targeting the value of targeted therapy

https://doi.org/10.18632/oncotarget.21596

Joseph C. Del Paggio, Richard Sullivan, and Christopher M. Booth
90612-90613
Abstract  |  PDF  |  How to cite

Targeting multiple nodes of MLL complexes to improve leukemia therapy

https://doi.org/10.18632/oncotarget.21598

Caroline Dafflon, Ralph Tiedt, and Jürg Schwaller
90614-90615
Abstract  |  PDF  |  How to cite

Our young cancer patients talk—we learn

https://doi.org/10.18632/oncotarget.21599

Andrea Ferrari, and Maura Massimino
90616-90617
Abstract  |  PDF  |  How to cite

Autologous transplant for myeloma: when the old meets the new

https://doi.org/10.18632/oncotarget.21605

Francesca Gay, Mariella Genuardi, and Mario Boccadoro
90618-90619
Abstract  |  PDF  |  How to cite

miR301a mediated immune evasion by Japanese encephalitis virus

https://doi.org/10.18632/oncotarget.21674

Bibhabasu Hazra, Surajit Chakraborty, and Anirban Basu
90620-90621
Abstract  |  PDF  |  How to cite

Multifaceted CK2 in malignant and healthy T cells

https://doi.org/10.18632/oncotarget.21700

Sérgio T. Ribeiro, João T. Barata, and Bruno Silva-Santos
90622-90623
Abstract  |  PDF  |  How to cite

Targeting autoreactive germinal centers to curb autoimmunity

https://doi.org/10.18632/oncotarget.21701

Søren E. Degn, Cees E. van der Poel, and Michael C. Carroll
90624-90625
Abstract  |  PDF  |  How to cite

Cobll1: A new player in CML

https://doi.org/10.18632/oncotarget.21705

Hongtae Kim, Dong-Wook Kim, and Kyungjae Myung
90626-90627
Abstract  |  PDF  |  How to cite

Traceback: leveraging archived biospecimens to identify mutation carriers

https://doi.org/10.18632/oncotarget.21742

Goli Samimi, and Mark E. Sherman
90628-90629
Abstract  |  PDF  |  How to cite

Tolerogenic dendritic cellbased immunotherapy

https://doi.org/10.18632/oncotarget.21867

Kiyuk Chang, Jie-Young Song, and Dae-Seog Lim
90630-90631
Abstract  |  PDF  |  How to cite

Microvesicles in CLL: predictor of disease progression/relapse

https://doi.org/10.18632/oncotarget.21868

Guru P. Maiti, Neil E. Kay, and Asish K. Ghosh
90632-90633
Abstract  |  PDF  |  How to cite

Integrative cancer care: crossing communication barriers

https://doi.org/10.18632/oncotarget.21890

Eran Ben-Arye, and Noah Samuels
90634-90635
Abstract  |  PDF  |  How to cite

Unproven stem cell therapy for macular degeneration

https://doi.org/10.18632/oncotarget.21891

Zubair A. Ansari, Ajay E. Kuriyan, and Thomas A. Albini
90636-90637
Abstract  |  PDF  |  How to cite

Priority Research Papers

Deregulated cMyc requires a functional HSF1 for experimental and human hepatocarcinogenesis

https://doi.org/10.18632/oncotarget.21469

Antonio Cigliano, Maria G. Pilo, Lei Li, Gavinella Latte, Marta Szydlowska, Maria M. Simile, Panagiotis Paliogiannis, Li Che, Giovanni M. Pes, Giuseppe Palmieri, Maria C. Sini, Antonio Cossu, Alberto Porcu, Gianpaolo Vidili, Maria A. Seddaiu, Rosa M. Pascale, Silvia Ribback, Frank Dombrowski, Xin Chen, and Diego F. Calvisi
90638-90650
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cancermutated ribosome protein L22 RPL22/eL22 suppresses cancer cell survival by blocking p53MDM2 circuit

https://doi.org/10.18632/oncotarget.21544

Bo Cao, Ziling Fang, Peng Liao, Xiang Zhou, Jianping Xiong, Shelya Zeng, and Hua Lu
90651-90661
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CDK1 promotes nascent DNA synthesis and induces resistance of cancer cells to DNAdamaging therapeutic agents

https://doi.org/10.18632/oncotarget.21730

Hongwei Liao, Fang Ji, Xinwei Geng, Meichun Xing, Wen Li, Zhihua Chen, Huahao Shen, and Songmin Ying
90662-90673
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

UVBinduced nuclear translocation of TCPTP by AKT/1433σ axis inhibits keratinocyte survival and proliferation

https://doi.org/10.18632/oncotarget.21794

Mihwa Kim, Liza D. Morales, Minwoo Baek, Thomas J. Slaga, John DiGiovanni, and Dae Joon Kim
90674-90692
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Pathology

Inhibition of Miro1 disturbs mitophagy and pancreatic βcell function interfering insulin release via IRSAktFoxo1 in diabetes

https://doi.org/10.18632/oncotarget.20963

Lingling Chen, Chunyan Liu, Jianfeng Gao, Zhiwen Xie, Lawrence W.C. Chan, Damien J. Keating, Yibin Yang, Jiazhong Sun, Fuling Zhou, Yongchang Wei, Xiuli Men, and Sijun Yang
90693-90705
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Low expression of SerpinB2 is associated with reduced survival in lung adenocarcinomas

https://doi.org/10.18632/oncotarget.21456

Maria Ramnefjell, Christina Aamelfot, Lars Helgeland, and Lars A. Akslen
90706-90718
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Automated histological classification of whole slide images of colorectal biopsy specimens

https://doi.org/10.18632/oncotarget.21819

Hiroshi Yoshida, Yoshiko Yamashita, Taichi Shimazu, Eric Cosatto, Tomoharu Kiyuna, Hirokazu Taniguchi, Shigeki Sekine, and Atsushi Ochiai
90719-90729
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Host cell transcriptome modification upon exogenous HPV16 L2 protein expression

https://doi.org/10.18632/oncotarget.21817

Xinwei An, Yuhan Hao, and Patricio I. Meneses
90730-90747
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Immunology

Dissecting the mechanisms involved in antihuman Tlymphocyte immunoglobulin ATGinduced tolerance in the setting of allogeneic stem cell transplantation potential implications for graft versus host disease

https://doi.org/10.18632/oncotarget.21797

Katia Beider, David Naor, Valeria Voevoda, Olga Ostrovsky, Hanna Bitner, Evgenia Rosenberg, Nira Varda-Bloom, Victoria Marcu-Malina, Jonathan Canaani, Ivetta Danilesko, Avichai Shimoni, and Arnon Nagler
90748-90765
Abstract  |  PDF  |  Full Text  |  How to cite

The TRPV1 ion channel regulates thymocyte differentiation by modulating autophagy and proteasome activity

https://doi.org/10.18632/oncotarget.21798

Consuelo Amantini, Valerio Farfariello, Claudio Cardinali, Maria Beatrice Morelli, Oliviero Marinelli, Massimo Nabissi, Matteo Santoni, Laura Bonfili, Valentina Cecarini, Anna Maria Eleuteri, and Giorgio Santoni
90766-90780
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effects of baicalein on IL1βinduced inflammation and apoptosis in rat articular chondrocytes

https://doi.org/10.18632/oncotarget.21796

Yue Li, Jinglu Wang, Xiaopeng Song, Hui Bai, Tianwen Ma, Zhiheng Zhang, Xinran Li, Renli Jiang, Guanying Wang, Xiaojing Fan, Xu Liu, and Li Gao
90781-90795
Abstract  |  PDF  |  Full Text  |  How to cite

Canis familiaris allergen Can f 6: expression purification and analysis of Bcell epitopes in Chinese dog allergic children

https://doi.org/10.18632/oncotarget.21822

Yu-Jie Wang, Lin Li, Wei-Juan Song, Yan-Jun Zhou, Meng-Da Cao, Xiang-Rong Zuo, and Ji-Fu Wei
90796-90807
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

VEGF121 is predictor for survival in activated Bcelllike diffuse large Bcell lymphoma and is related to an immune response gene signature conserved in cancers

https://doi.org/10.18632/oncotarget.19385

Julien Broséus, Samia Mourah, Gérard Ramstein, Sophie Bernard, Nicolas Mounier, Wendy Cuccuini, Philippe Gaulard, Christian Gisselbrecht, Josette Brière, Rémi Houlgatte, and Catherine Thieblemont
90808-90824
Abstract  |  PDF  |  Full Text  |  How to cite

Combination therapy with an OX40L fusion protein and a vaccine targeting the transcription factor twist inhibits metastasis in a murine model of breast cancer

https://doi.org/10.18632/oncotarget.19967

Anthony S. Malamas, Scott A. Hammond, Jeffrey Schlom, and James W. Hodge
90825-90841
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cyclin A2 regulates homologous recombination DNA repair and sensitivity to DNA damaging agents and polyADPribose polymerase PARP inhibitors in human breast cancer cells

https://doi.org/10.18632/oncotarget.20412

Wei Wei Gu, Jie Lin, and Xing Yu Hong
90842-90851
Abstract  |  PDF  |  Full Text  |  How to cite

GSTA1 diplotypes affect busulfan clearance and toxicity in children undergoing allogeneic hematopoietic stem cell transplantation: a multicenter study

https://doi.org/10.18632/oncotarget.20310

Marc Ansari, Patricia Huezo-Diaz Curtis, Chakradhara Rao S. Uppugunduri, Mohammed Aziz Rezgui, Tiago Nava, Vid Mlakar, Laurence Lesne, Yves Théoret, Yves Chalandon, Lee L. Dupuis, Tao Schechter, Imke H. Bartelink, Jaap J. Boelens, Robbert Bredius, Jean-Hugues Dalle, Saba Azarnoush, Petr Sedlacek, Victor Lewis, Martin Champagne, Christina Peters, Henrique Bittencourt, and Maja Krajinovic
90852-90867
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reciprocal regulation of DGCR5 and miR320a affects the cellular malignant phenotype and 5FU response in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.18377

Sun Yong, Yu Yabin, Zhou Bing, Zhu Chuanrong, Gu Dianhua, Zhang Jianhuai, Yuan Weidong, Wang Shuming, and Liu Ling
90868-90878
Abstract  |  PDF  |  Full Text  |  How to cite

Integration of microRNAome proteomics and metabolomics to analyze arsenicinduced malignant cell transformation

https://doi.org/10.18632/oncotarget.18741

Youyou Zhou, Yanfu Wang, Juan Su, Zheng Wu, Chao Wang, Weiming Zhong, Xiaomei Liu, Linhui Cui, Xiaoyu Zhou, Yufang Ma, Yi Xin, Jianglin Zhang, Lisha Wu, Xing Hu, Xiang Chen, Cong Peng, and Mingyang Gao
90879-90896
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The positivity of Gproteincoupled receptor30 GPR 30 an alternative estrogen receptor is not different between type 1 and type 2 endometrial cancer

https://doi.org/10.18632/oncotarget.18545

Jiayi Wan, Yongxiang Yin, Min Zhao, Fang Shen, Miaoxin Chen, and Qi Chen
90897-90904
Abstract  |  PDF  |  Full Text  |  How to cite

The antitumor effect of arsenic trioxide on hepatocellular carcinoma is enhanced by andrographolide

https://doi.org/10.18632/oncotarget.18677

Xuhua Duan, Tengfei Li, Xinwei Han, Jianzhuang Ren, Pengfei Chen, Hao Li, and Shaojun Gong
90905-90915
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Changes in renal function indices in cirrhotic chronic hepatitis C patients treated with sofosbuvircontaining regimens

https://doi.org/10.18632/oncotarget.18701

Jianhong Chen, Xiaxia Zhang, Hao Luo, Chihong Wu, Min Yu, Dan Liu, Hongli Xi, Yihang Zhou, Yaoyu An, and Xiaoyuan Xu
90916-90924
Abstract  |  PDF  |  Full Text  |  How to cite

Danshen improves survival of patients with advanced lung cancer and targeting the relationship between macrophages and lung cancer cells

https://doi.org/10.18632/oncotarget.18767

Ching-Yuan Wu, Jong-Yuh Cherng, Yao-Hsu Yang, Chun-Liang Lin, Feng-Che Kuan, Yin-Yin Lin, Yu-Shih Lin, Li-Hsin Shu, Yu-Ching Cheng, Hung Te Liu, Ming-Chu Lu, Jthau Lung, Pau-Chung Chen, Hui Kuan Lin, Kuan-Der Lee, and Ying-Huang Tsai
90925-90947
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PIK3CA mutations are associated with increased tumor aggressiveness and Akt activation in gastric cancer

https://doi.org/10.18632/oncotarget.18770

Ji-Won Kim, Hye Seung Lee, Kyung Han Nam, Soyeon Ahn, Jin Won Kim, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim, and Keun-Wook Lee
90948-90958
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PKM2 activation sensitizes cancer cells to growth inhibition by 2deoxyDglucose

https://doi.org/10.18632/oncotarget.19630

Sui Seng Tee, Jae Mo Park, Ralph E. Hurd, Kyle R. Brimacombe, Matthew B. Boxer, Tarik F. Massoud, Brian K. Rutt, and Daniel M. Spielman
90959-90968
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Phenotypic and clinical characterization of low density neutrophils in patients with advanced lung adenocarcinoma

https://doi.org/10.18632/oncotarget.18771

Yangyang Liu, Yue Hu, Feifei Gu, Jinyan Liang, Yulan Zeng, Xiaohua Hong, Kai Zhang, and Li Liu
90969-90978
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Neuroprotective effect of a novel gastrodin derivative against ischemic brain injury: involvement of peroxiredoxin and TLR4 signaling inhibition

https://doi.org/10.18632/oncotarget.18773

Xiao-Na Mao, Hong-Jing Zhou, Xiao-Jia Yang, Li-Xue Zhao, Xi Kuang, Chu Chen, Dong-Ling Liu, and Jun-Rong Du
90979-90995
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antitumor activity of gemcitabine against highgrade meningioma in vitro and in vivo

https://doi.org/10.18632/oncotarget.18827

Hiroyuki Takeda, Masashi Okada, Kenta Kuramoto, Shuhei Suzuki, Hirotsugu Sakaki, Tomomi Sanomachi, Shizuka Seino, Takashi Yoshioka, Hirofumi Hirano, Kazunori Arita, and Chifumi Kitanaka
90996-91008
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TXNDC5 is a cervical tumor susceptibility gene that stimulates cell migration vasculogenic mimicry and angiogenesis by downregulating SERPINF1 and TRAF1 expression

https://doi.org/10.18632/oncotarget.18857

Bing Xu, Jian Li, Xiaoxin Liu, Chang Li, and Xiaotian Chang
91009-91024
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic variation of lncRNA GAS5 contributes to the development of lung cancer

https://doi.org/10.18632/oncotarget.19955

Weihao Li, Kai Huang, Fengbiao Wen, Guanghui Cui, Haizhou Guo, and Song Zhao
91025-91029
Abstract  |  PDF  |  Full Text  |  How to cite

The performance of 11CMethionine PET in the differential diagnosis of glioma recurrence

https://doi.org/10.18632/oncotarget.19024

Weilin Xu, Liansheng Gao, Anwen Shao, Jingwei Zheng, and Jianmin Zhang
91030-91039
Abstract  |  PDF  |  Full Text  |  How to cite

Isoxazole compound ML327 blocks MYC expression and tumor formation in neuroblastoma

https://doi.org/10.18632/oncotarget.19406

Eric J. Rellinger, Chandrasekhar Padmanabhan, Jingbo Qiao, Brian T. Craig, Hanbing An, Jing Zhu, Hernán Correa, Alex G. Waterson, Craig W. Lindsley, R. Daniel Beauchamp, and Dai H. Chung
91040-91051
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Autophagy suppression potentiates the antiglioblastoma effect of asparaginase in vitro and in vivo

https://doi.org/10.18632/oncotarget.19409

Qicheng Chen, Li Ye, Jiajun Fan, Xuyao Zhang, Huan Wang, Siyang Liao, Ping Song, Ziyu Wang, Shaofei Wang, Yubin Li, Jingyun Luan, Yichen Wang, Wei Chen, Wenjing Zai, Ping Yang, Zhonglian Cao, and Dianwen Ju
91052-91066
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Stanniocalcin2 acts as an anorectic factor through activation of STAT3 pathway

https://doi.org/10.18632/oncotarget.19412

Yang Jiao, Jiejie Zhao, Guojun Shi, Xing Liu, Xuelian Xiong, Xiaoying Li, Huijie Zhang, Qinyun Ma, and Yan Lu
91067-91075
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Perioperative outcomes of robotic surgery for the treatment of lung cancer compared to a conventional videoassisted thoracoscopic surgery VATS technique

https://doi.org/10.18632/oncotarget.19533

Zipu Yu, Qiong Xie, Lei Guo, Xin Chen, Chenyao Ni, Wenzong Luo, Weidong Li, and Liang Ma
91076-91084
Abstract  |  PDF  |  Full Text  |  How to cite

Orellanine specifically targets renal clear cell carcinoma

https://doi.org/10.18632/oncotarget.19555

Lisa Buvall, Heidi Hedman, Alina Khramova, Deman Najar, Lovisa Bergwall, Kerstin Ebefors, Carina Sihlbom, Sven Lundstam, Anders Herrmann, Hanna Wallentin, Emelie Roos, Ulf A. Nilsson, Martin Johansson, Jan Törnell, Börje Haraldsson, and Jenny Nyström
91085-91098
Abstract  |  PDF  |  Full Text  |  How to cite

Sigma1 and Sigma2 receptor ligands induce apoptosis and autophagy but have opposite effect on cell proliferation in uveal melanoma

https://doi.org/10.18632/oncotarget.19556

Lucia Longhitano, Carlo Castruccio Castracani, Daniele Tibullo, Roberto Avola, Maria Viola, Giuliano Russo, Orazio Prezzavento, Agostino Marrazzo, Emanuele Amata, Michele Reibaldi, Antonio Longo, Andrea Russo, Nunziatina Laura Parrinello, and Giovanni Li Volti
91099-91111
Abstract  |  PDF  |  Full Text  |  How to cite

Genetic deletion of Rnd3 in neural stem cells promotes proliferation via upregulation of Notch signaling

https://doi.org/10.18632/oncotarget.20247

Huimin Dong, Xi Lin, Yuntao Li, Ronghua Hu, Yang Xu, Xiaojie Guo, Qiong La, Shun Wang, Congcong Fang, Junli Guo, Qi Li, Shanping Mao, and Baohui Liu
91112-91122
Abstract  |  PDF  |  Full Text  |  How to cite

Shp2 regulates migratory behavior and response to EGFRTKIs through ERK1/2 pathway activation in nonsmall cell lung cancer cells

https://doi.org/10.18632/oncotarget.20249

Yu-Jing Sun, Zhong-Ling Zhuo, Hai-Peng Xian, Ke-Zhong Chen, Fan Yang, and Xiao-Tao Zhao
91123-91133
Abstract  |  PDF  |  Full Text  |  How to cite

Tetrahydrocurcumin induces mesenchymalepithelial transition and suppresses angiogenesis by targeting HIF1α and autophagy in human osteosarcoma

https://doi.org/10.18632/oncotarget.19845

Yan Zhang, Ying Liu, Jilong Zou, Lixin Yan, Wei Du, Yafeng Zhang, Hanliang Sun, Peng Lu, Shuo Geng, Rui Gu, Hongyue Zhang, and Zhenggang Bi
91134-91149
Abstract  |  PDF  |  Full Text  |  How to cite

Addition of 5fluorouracil to firstline induction chemotherapy with docetaxel and cisplatin before concurrent chemoradiotherapy does not improve survival in locoregionally advanced nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.20017

Wang Fangzheng, Jiang Chuner, Wang Lei, Yan Fengqin, Ye Zhimin, Sun Quanquan, Liu Tongxin, Xu Min, Wu Peng, Long Bin, Rihito Aizawa, Masoto Sakamoto, and Fu Zhenfu
91150-91161
Abstract  |  PDF  |  Full Text  |  How to cite

CaMKII is involved in subcellular Ca2+ redistributioninduced endoplasmic reticulum stress leading to apoptosis in primary cultures of rat proximal tubular cells exposed to lead

https://doi.org/10.18632/oncotarget.20035

Min-Ge Wang, Wen-Hui Li, Xin-Yu Wang, Du-Bao Yang, Zhen-Yong Wang, and Lin Wang
91162-91173
Abstract  |  PDF  |  Full Text  |  How to cite

Treatment plan comparison between TriCo60 magneticresonance imageguided radiation therapy and volumetric modulated arc therapy for prostate cancer

https://doi.org/10.18632/oncotarget.20039

Jong Min Park, So-Yeon Park, Chang Heon Choi, Minsoo Chun, Jin Ho Kim, and Jung-In Kim
91174-91184
Abstract  |  PDF  |  Full Text  |  How to cite

SOCS2 overexpression alleviates diabetic nephropathy in rats by inhibiting the TLR4/NFκB pathway

https://doi.org/10.18632/oncotarget.20434

Suxia Yang, Junwei Zhang, Shiying Wang, Xinxin Zhao, and Jun Shi
91185-91198
Abstract  |  PDF  |  Full Text  |  How to cite

Characterization of urinary extracellular vesicle proteins in muscleinvasive bladder cancer

https://doi.org/10.18632/oncotarget.20043

Christopher R. Silvers, Hiroshi Miyamoto, Edward M. Messing, George J. Netto, and Yi-Fen Lee
91199-91208
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Wheat germ agglutinininduced paraptosislike cell death and protective autophagy is mediated by autophagylinked FYVE inhibition

https://doi.org/10.18632/oncotarget.20436

Tsung Lin Tsai, Hao Chen Wang, Chun Hua Hung, Peng Chan Lin, Yi San Lee, Helen H.W. Chen, and Wu Chou Su
91209-91222
Abstract  |  PDF  |  Full Text  |  How to cite

Jolkinolide B induces apoptosis of colorectal carcinoma through ROSER stressCa2+mitochondria dependent pathway

https://doi.org/10.18632/oncotarget.20077

Jing Zhang, Yang Wang, Ye Zhou, and Qing-Yu He
91223-91237
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Comparative efficacy of different chemotherapies for nonHodgkin lymphoma: a networkmeta analysis

https://doi.org/10.18632/oncotarget.20437

Pengcheng Cai, Jinjin Hao, Dan Wang, and Jiawei Xu
91238-91247
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Accurate quantification of 5Methylcytosine 5Hydroxymethylcytosine 5Formylcytosine and 5Carboxylcytosine in genomic DNA from breast cancer by chemical derivatization coupled with ultra performance liquid chromatography electrospray quadrupole time of flight mass spectrometry analysis

https://doi.org/10.18632/oncotarget.20093

Mengzhe Guo, Xiao Li, Liyan Zhang, Dantong Liu, Wencheng Du, Dengyang Yin, Nan Lyu, Guangyu Zhao, Cheng Guo, and Daoquan Tang
91248-91257
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A small molecule E2methoxy434methoxyphenyl prop1en1yl phenol suppresses tumor growth via inhibition of IkappaB kinase β in colorectal cancer in vivo and in vitro

https://doi.org/10.18632/oncotarget.20440

Jie Zheng, Mi Hee Park, Hee Pom Lee, Byung Kook Hyun, Hyung Ok Chun, Sung Hee Jung, Hyun Ok Seo, Young Wan Ham, Sang-Bae Han, and Jin Tae Hong
91258-91269
Abstract  |  PDF  |  Full Text  |  How to cite

Crosstalk in competing endogenous RNA network reveals the complex molecular mechanism underlying lung cancer

https://doi.org/10.18632/oncotarget.20441

Xiang Jin, Yinghui Guan, Hui Sheng, and Yang Liu
91270-91280
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

LncRNAUCA1 enhances MMP13 expression by inhibiting miR 2045p in human chondrocytes

https://doi.org/10.18632/oncotarget.20108

Guodong Wang, Xianmin Bu, Yuanmin Zhang, Xiaowei Zhao, Ying Kong, Longfei Ma, Shuaishuai Niu, Bin Wu, and Chunyang Meng
91281-91290
Abstract  |  PDF  |  Full Text  |  How to cite

Protection by simvastatin on hyperglycemiainduced endothelial dysfunction through inhibiting NLRP3 inflammasomes

https://doi.org/10.18632/oncotarget.20443

Zhen-Huan Lv, Trinh Anh Phuong, Shi-Jie Jin, Xiao-Xue Li, and Ming Xu
91291-91305
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Nitidine chloride acts as an apoptosis inducer in human oral cancer cells and a nude mouse xenograft model via inhibition of STAT3

https://doi.org/10.18632/oncotarget.20444

Lee-Han Kim, Sachita Khadka, Ji-Ae Shin, Ji-Youn Jung, Mi-Heon Ryu, Hyun-Ju Yu, Hae Nim Lee, Boonsil Jang, In-Hyoung Yang, Dong-Hoon Won, Hye-Jeong Kwon, Joseph H. Jeong, Seong Doo Hong, Nam-Pyo Cho, and Sung-Dae Cho
91306-91315
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TGFβ1 induces hypertrophic change and expression of angiogenic factors in human chondrocytes

https://doi.org/10.18632/oncotarget.20509

Jie-Lin Chen, Chang Zou, Yunfang Chen, Weimin Zhu, Wei Liu, Jianghong Huang, Qisong Liu, Daming Wang, Li Duan, Jianyi Xiong, Jiaming Cui, Zhaofeng Jia, and Daping Wang
91316-91327
Abstract  |  PDF  |  Full Text  |  How to cite

Response to transarterial chemoembolization may serve as selection criteria for hepatocellular carcinoma liver transplantation

https://doi.org/10.18632/oncotarget.20511

Jianyong Lei, Jinjing Zhong, Yefang Luo, Lunan Yan, Jingqiang Zhu, Wentao Wang, Bo Li, Tianfu Wen, and Jiaying Yang Liver Surgery Group
91328-91342
Abstract  |  PDF  |  Full Text  |  How to cite

CASC15 gene polymorphisms reduce neuroblastoma risk in Chinese children

https://doi.org/10.18632/oncotarget.20514

Jiao Zhang, Zhen-Jian Zhuo, Jiaxiang Wang, Jing He, Lin Yang, Da Zhang, Pan Qin, and Lizhao Yan
91343-91349
Abstract  |  PDF  |  Full Text  |  How to cite

Sulodexide recovers endothelial function through reconstructing glycocalyx in the ballooninjury rat carotid artery model

https://doi.org/10.18632/oncotarget.20518

Tianjia Li, Xinnong Liu, Zhewei Zhao, Leng Ni, and Changwei Liu
91350-91361
Abstract  |  PDF  |  Full Text  |  How to cite

Upregulation of miR181a impairs hepatic glucose and lipid homeostasis

https://doi.org/10.18632/oncotarget.20523

Xiliang Du, Yuchen Yang, Chuang Xu, Zhicheng Peng, Min Zhang, Lin Lei, Wenwen Gao, Yuhao Dong, Zhen Shi, Xudong Sun, Zhe Wang, Xiaobing Li, Xinwei Li, and Guowen Liu
91362-91378
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Matrix metalloproteinase1 expression in breast carcinoma: a marker for unfavorable prognosis

https://doi.org/10.18632/oncotarget.20557

Ji Wang, Chenyang Ye, Demin Lu, Yongxia Chen, Yunlu Jia, Xiaogang Ying, Hanchu Xiong, Wenhe Zhao, Jichun Zhou, and Linbo Wang
91379-91390
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IQCATAVV: To explore the effect of Pselectin GPIIb/IIIa IL2 IL6 and IL8 on deep venous thrombosis

https://doi.org/10.18632/oncotarget.20588

Jianhui Wu, Haimei Zhu, Guodong Yang, Yuji Wang, Yaonan Wang, Shurui Zhao, Ming Zhao, and Shiqi Peng
91391-91401
Abstract  |  PDF  |  Full Text  |  How to cite

Melatonin enhances sorafenib actions in human hepatocarcinoma cells by inhibiting mTORC1/p70S6K/HIF1α and hypoxiamediated mitophagy

https://doi.org/10.18632/oncotarget.20592

Néstor Prieto-Domínguez, Carolina Méndez-Blanco, Sara Carbajo-Pescador, Flavia Fondevila, Andrés García-Palomo, Javier González-Gallego, and José L. Mauriz
91402-91414
Abstract  |  PDF  |  Full Text  |  How to cite

Genetic variations in LIGHT are associated with susceptibility to ankylosing spondylitis in a Chinese Han population

https://doi.org/10.18632/oncotarget.20644

Bin Yang, Junlong Zhang, Lixin Li, Xiaojun Lyu, Wei Wei, Zhuochun Huang, Bei Cai, and Lanlan Wang
91415-91424
Abstract  |  PDF  |  Full Text  |  How to cite

Egr1 regulates RTA transcription through a cooperative involvement of transcriptional regulators

https://doi.org/10.18632/oncotarget.20648

Roni Sarkar, and Subhash C. Verma
91425-91444
Abstract  |  PDF  |  Full Text  |  How to cite

CCR6 is required for ligandinduced CatSper activation in human sperm

https://doi.org/10.18632/oncotarget.20651

Ruiying Diao, Tao Wang, Kin Lam Fok, Xiaofeng Li, Yechun Ruan, Mei Kuen Yu, Yimin Cheng, Ying Chen, Hao Chen, Lisha Mou, Xueyong Cai, Yan Wang, Zhiming Cai, Xuhui Zeng, and Hsiao Chang Chan
91445-91458
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Discovery of novel frizzled7 inhibitors by targeting the receptor’s transmembrane domain

https://doi.org/10.18632/oncotarget.20665

Wei Zhang, Wenyan Lu, Subramaniam Ananthan, Mark J. Suto, and Yonghe Li
91459-91470
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of RAD51B predicts a preferable prognosis for nonsmall cell lung cancer patients

https://doi.org/10.18632/oncotarget.20676

Mengyin Wu, Zufeng Sheng, Lingyan Jiang, Zhengyuan Liu, Yuhua Bi, and Yueping Shen
91471-91480
Abstract  |  PDF  |  Full Text  |  How to cite

23 4dihydroxybenzylidenemalononitrile as a novel antimelanogenic compound

https://doi.org/10.18632/oncotarget.20690

Bonggi Lee, Kyoung Mi Moon, Jong Seung Lim, Yeojin Park, Do Hyun Kim, Sujin Son, Hyoung Oh Jeong, Dae Hyun Kim, Eun Kyeong Lee, Ki Wung Chung, Hye Jin An, Pusoon Chun, Arnold Y. Seo, Ju-Hye Yang, Bong-Seon Lee, Jin Yeul Ma, Won-Kyung Cho, Hyung Ryong Moon, and Hae Young Chung
91481-91493
Abstract  |  PDF  |  Full Text  |  How to cite

Genetic polymorphisms of ATG5 predict survival and recurrence in patients with earlystage esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.20793

Pei-Wen Yang, Min-Shu Hsieh, Ya-Han Chang, Pei-Ming Huang, and Jang-Ming Lee
91494-91504
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Immunization with recombinant rabies virus expressing Interleukin18 exhibits enhanced immunogenicity and protection in mice

https://doi.org/10.18632/oncotarget.21065

Weiwei Gai, Wenwen Zheng, Chong Wang, Gary Wong, Yanyan Song, and Xuexing Zheng
91505-91515
Abstract  |  PDF  |  Full Text  |  How to cite

Tumorassociated macrophages promote neuroblastoma via STAT3 phosphorylation and upregulation of cMYC

https://doi.org/10.18632/oncotarget.21066

Michael D. Hadjidaniel, Sakunthala Muthugounder, Long T. Hung, Michael A. Sheard, Soheila Shirinbak, Randall Y. Chan, Rie Nakata, Lucia Borriello, Jemily Malvar, Rebekah J. Kennedy, Hiroshi Iwakura, Takashi Akamizu, Richard Sposto, Hiroyuki Shimada, Yves A. DeClerck, and Shahab Asgharzadeh
91516-91529
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA218 inhibits proliferation and invasion in ovarian cancer by targeting Runx2

https://doi.org/10.18632/oncotarget.21069

Na Li, Lufei Wang, Guangyun Tan, Zhiheng Guo, Lei Liu, Ming Yang, and Jin He
91530-91541
Abstract  |  PDF  |  Full Text  |  How to cite

Shikonin protects against DGalactosamine and lipopolysaccharideinduced acute hepatic injury by inhibiting TLR4 signaling pathway

https://doi.org/10.18632/oncotarget.21070

Meng-Xiang Lin, Yong-Xiang Yi, Pei-Pei Fang, Shan-Shan Huang, Chen-Wei Pan, Ling-Xiang Jin, Tong Zhang, and Guang-Yao Zhou
91542-91550
Abstract  |  PDF  |  Full Text  |  How to cite

miR15b represses BACE1 expression in sporadic Alzheimer’s disease

https://doi.org/10.18632/oncotarget.21177

Guohua Gong, Fengmao An, Yu Wang, Ming Bian, Li-Jun Yu, and Chengxi Wei
91551-91557
Abstract  |  PDF  |  Full Text  |  How to cite

Integrative analysis to identify oncogenic gene expression changes associated with copy number variations of enhancer in ovarian cancer

https://doi.org/10.18632/oncotarget.21227

Xiaoyan Li, Yining Liu, Jiachun Lu, and Min Zhao
91558-91567
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prevalence of and risk factors for cystic echinococcosis among herding families in five provinces in western China: a crosssectional study

https://doi.org/10.18632/oncotarget.21229

Ruixia Yuan, Hairong Wu, Heng Zeng, Ping Liu, Quangang Xu, Lu Gao, Yin Li, Rendong Li, Duan Huang, Chuanhua Yu, and Xiangdong Sun
91568-91576
Abstract  |  PDF  |  Full Text  |  How to cite

Genetic or pharmacologic inhibition of EGFR ameliorates sepsisinduced AKI

https://doi.org/10.18632/oncotarget.21244

Xuan Xu, Juan Wang, Ruhao yang, Zheng Dong, and Dongshan Zhang
91577-91592
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Breath analysis by gas chromatographymass spectrometry and electronic nose to screen for pleural mesothelioma: a crosssectional casecontrol study

https://doi.org/10.18632/oncotarget.21335

Kevin Lamote, Paul Brinkman, Lore Vandermeersch, Matthijs Vynck, Peter J. Sterk, Herman Van Langenhove, Olivier Thas, Joris Van Cleemput, Kristiaan Nackaerts, and Jan P. van Meerbeeck
91593-91602
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA92b inhibits epithelialmesenchymal transitioninduced migration and invasion by targeting Smad3 in nasopharyngeal cancer

https://doi.org/10.18632/oncotarget.21342

Chong Zhao, Feipeng Zhao, Huajun Feng, Shengen Xu, and Gang Qin
91603-91613
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Ginkgo biloba extract EGb 761–induced upregulation of LincRNAp21 inhibits colorectal cancer metastasis by associating with EZH2

https://doi.org/10.18632/oncotarget.21345

Tingting Liu, Junzhong Zhang, Zhongqiu Chai, Gang Wang, Naiqiang Cui, and Bing Zhou
91614-91627
Abstract  |  PDF  |  Full Text  |  How to cite

Thoracic endovascular aortic repair for type B aortic dissection after renal transplantation

https://doi.org/10.18632/oncotarget.21399

Chang Shu, QingGen Xiong, Jian Qiu, MingYao Luo, and Kun Fang
91628-91635
Abstract  |  PDF  |  Full Text  |  How to cite

Comparison among conventional and advanced MRI 18FFDG PET/CT phenotype and genotype in glioblastoma

https://doi.org/10.18632/oncotarget.21482

Maria Consuelo Valentini, Marta Mellai, Laura Annovazzi, Antonio Melcarne, Tetyana Denysenko, Paola Cassoni, Cristina Casalone, Cristiana Maurella, Silvia Grifoni, Piercarlo Fania, Angelina Cistaro, and Davide Schiffer
91636-91653
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic polymorphisms in caveolin1 associate with breast cancer risk in Chinese Han population

https://doi.org/10.18632/oncotarget.21560

Meng Wang, Tian Tian, Xiaobin Ma, Wenge Zhu, Yan Guo, Zhao Duan, Jiangbo Fan, Shuai Lin, Kang Liu, Yi Zheng, Qianwen Sheng, Zhi-Jun Dai, and Huixia Peng
91654-91661
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Thiobarbituratederived compounds are novel antioxidants to prevent LPSinduced inflammation in the liver

https://doi.org/10.18632/oncotarget.21714

Kyoung Mi Moon, Bonggi Lee, Ji Won Jeong, Dae Hyun Kim, Yun Jung Park, Hye Rim Kim, Ji Young Park, Min Jo Kim, Hye Jin An, Eun Kyeong Lee, Young Mi Ha, Eunok Im, Pusoon Chun, Jin Yeul Ma, Won-Kyung Cho, Hyung Ryong Moon, and Hae Young Chung
91662-91673
Abstract  |  PDF  |  Full Text  |  How to cite

Circular RNA hsa_circ_000984 promotes colon cancer growth and metastasis by sponging miR106b

https://doi.org/10.18632/oncotarget.21748

Xiao-Wu Xu, Bo-An Zheng, Zhi-Ming Hu, Zhen-Yuan Qian, Chao-Jie Huang, Xi-Qiang Liu, and Wei-Ding Wu
91674-91683
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Meta-Analysis

Dietary n3 polyunsaturated fatty acids fish consumption and endometrial cancer risk: a metaanalysis of epidemiological studies

https://doi.org/10.18632/oncotarget.18295

Rui Hou, Shen-Shen Yao, Jia Liu, Lian-Lian Wang, Lang Wu, and Luo Jiang
91684-91693
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Systematic review and metaanalysis of the prognostic value of preoperative platelettolymphocyte ratio in patients with urothelial carcinoma

https://doi.org/10.18632/oncotarget.21162

Shuiqing Wu, Qi Wan, Ran Xu, Xuan Zhu, Haiqing He, and Xiaokun Zhao
91694-91702
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Italian real life experience with brentuximab vedotin: results of a large observational study on 234 relapsed/refractory Hodgkin’s lymphoma

https://doi.org/10.18632/oncotarget.18114

Cinzia Pellegrini, Alessandro Broccoli, Alessandro Pulsoni, Luigi Rigacci, Caterina Patti, Guido Gini, Donato Mannina, Monica Tani, Chiara Rusconi, Alessandra Romano, Anna Vanazzi, Barbara Botto, Armando Santoro, Stefan Hoaus, Gian Matteo Rigolin, Pellegrino Musto, Patrizio Mazza, Stefano Molica, Paolo Corradini, Angelo Fama, Francesco Gaudio, Michele Merli, Fioravante Ronconi, Giuseppe Gritti, Daniele Vallisa, Patrizia Tosi, Anna Marina Liberati, Antonello Pinto, Vincenzo Pavone, Filippo Gherlinzoni, Maria Paola Bianchi, Stefano Volpetti, Livio Trentin, Maria Cecilia Goldaniga, Maurizio Bonfichi, Amalia De Renzo, Corrado Schiavotto, Michele Spina, Angelo Michele Carella, Vittorio Stefoni, Lisa Argnani, and Pier Luigi Zinzani
91703-91710
Abstract  |  PDF  |  Full Text  |  How to cite

Correlation between cerebellar metabolism and poststroke depression in patients with ischemic stroke

https://doi.org/10.18632/oncotarget.21063

Lei Zhang, Muzi Li, and Rubo Sui
91711-91722
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Histone demethylase JMJD2C: epigenetic regulators in tumors

https://doi.org/10.18632/oncotarget.19176

Chengcheng Zhang, Zhongqi Wang, Qing Ji, and Qi Li
91723-91733
Abstract  |  PDF  |  Full Text  |  How to cite

Over forty years of bladder cancer glycobiology: Where do glycans stand facing precision oncology

https://doi.org/10.18632/oncotarget.19433

Rita Azevedo, Andreia Peixoto, Cristiana Gaiteiro, Elisabete Fernandes, Manuel Neves, Luís Lima, Lúcio Lara Santos, and José Alexandre Ferreira
91734-91764
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Noncoding RNA: a potential biomarker and therapeutic target for sepsis

https://doi.org/10.18632/oncotarget.21766

Tie-Ning Zhang, Da Li, Jing Xia, Qi-Jun Wu, Ri Wen, Ni Yang, and Chun-Feng Liu
91765-91778
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Recurrent glioma clinical trial CheckMate143: the game is not over yet

https://doi.org/10.18632/oncotarget.21586

Anna C. Filley, Mario Henriquez, and Mahua Dey
91779-91794
Abstract  |  PDF  |  Full Text  |  How to cite

Case Reports

Excellent response to chemotherapy post immunotherapy

https://doi.org/10.18632/oncotarget.20030

Ashish D. Dwary, Samip Master, Abhishek Patel, Constance Cole, Richard Mansour, Glenn Mills, Nebu Koshy, Prakash Peddi, Gary Burton, Dalia Hammoud, and Kavitha Beedupalli
91795-91802
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

Molecular targeting of the AuroraA/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells

https://doi.org/10.18632/oncotarget.20610

Mateusz Opyrchal, Malgorzata Gil, Jeffrey L. Salisbury, Mathew P. Goetz, Vera Suman, Amy Degnim, James McCubrey, Tufia Haddad, Ianko Iankov, Chenye B. Kurokawa, Nicole Shumacher, James N. Ingle, Evanthia Galanis, and Antonino B. D’Assoro
91803-91816
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite


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