Oncotarget

January 24, 2017

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About The Cover

The cover for issue 4 of Oncotarget features Figure 1A,  'FFPE samples are usually used for hematoxylin and eosin (H&E) and/or immunohistochemistry (IHC) stains. To overcome hurdles associated with gene expression analyses of tissue in FFPE samples, we show that the mH can increase the purification of high-quality RNA for downstream applications,' from Hoover, et al.

Table of Contents

News

p73 to the rescue: Role of RPL26

p73 to the rescue: Role of RPL26

https://doi.org/10.18632/oncotarget.14383

Xiao-Xin Sun,  and Mu-Shui Dai
5641-5642
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Editorial

Mu opioid receptor: from pain to glucose metabolism

Mu opioid receptor: from pain to glucose metabolism

https://doi.org/10.18632/oncotarget.14231

Eva Tudurí,  and Ruben Nogueiras
5643-5644
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AGEs and neurodegeneration: the Nrf2/glyoxalase-1 interaction

AGEs and neurodegeneration: the Nrf2/glyoxalase-1 interaction

https://doi.org/10.18632/oncotarget.14232

Raffaella Mastrocola
5645-5646
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Large-scale genomic deletions mediated by CRISPR/Cas9 system

Large-scale genomic deletions mediated by CRISPR/Cas9 system

https://doi.org/10.18632/oncotarget.14543

Yuning Song, Liangxue Lai,  and Zhanjun Li
5647-5647
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PRAK mediates Aβ-RAGE driven autophagy pathway

PRAK mediates Aβ-RAGE driven autophagy pathway

https://doi.org/10.18632/oncotarget.14544

Yoonhee Kim,  and Inhee Mook-Jung
5648-5649
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Uniquely conserved immunosuppressive viral exoribonucleases

Uniquely conserved immunosuppressive viral exoribonucleases

https://doi.org/10.18632/oncotarget.14548

Bjoern Meyer,  and Hinh Ly
5650-5651
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Epigenetic regulation of general anesthesia-induced neonatal neurodegeneration

Epigenetic regulation of general anesthesia-induced neonatal neurodegeneration

https://doi.org/10.18632/oncotarget.14568

Min Jia, Mu-Huo Ji,  and Jian-Jun Yang
5652-5653
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Editorial: Neuroscience

A circuitry for sleep in Parkinson´s disease

A circuitry for sleep in Parkinson´s disease

https://doi.org/10.18632/oncotarget.14000

Adriano D.S. Targa,  and Marcelo M.S. Lima
5654-5655
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Trapping the oligomers: new promises in neurosciences

Trapping the oligomers: new promises in neurosciences

https://doi.org/10.18632/oncotarget.13800

Thibaut Imberdis, Mike Robitzer,  and Véronique Perrier
5656-5657
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MiRNA-34 and stress response

MiRNA-34 and stress response

https://doi.org/10.18632/oncotarget.13923

Diego Andolina, Di Segni Matteo,  and Rossella Ventura
5658-5659
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Understanding histone deacetylation in Huntington’s disease

Understanding histone deacetylation in Huntington’s disease

https://doi.org/10.18632/oncotarget.13924

Luis Miguel Valor
5660-5661
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Regulation of RIC-3 and of nAChR expression

Regulation of RIC-3 and of nAChR expression

https://doi.org/10.18632/oncotarget.13925

Yael Ben-David,  and Millet Treinin
5662-5663
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Glutamate transporters: The arrestin connection

Glutamate transporters: The arrestin connection

https://doi.org/10.18632/oncotarget.13999

Francisco Zafra, Ignacio Ibáñez,  and Cecilio Giménez
5664-5665
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Progress in CSF biomarker discovery in sCJD

Progress in CSF biomarker discovery in sCJD

https://doi.org/10.18632/oncotarget.13998

Franc Llorens, Matthias Schmitz,  and Inga Zerr
5666-5667
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VTA BDNF enhances social stress-induced compulsive cocaine bingeing

VTA BDNF enhances social stress-induced compulsive cocaine bingeing

https://doi.org/10.18632/oncotarget.13995

Junshi Wang, Ryan M. Bastle,  and Ella M. Nikulina
5668-5669
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Pathophysiological role of zinc in ischemic brain injury

Pathophysiological role of zinc in ischemic brain injury

https://doi.org/10.18632/oncotarget.14003

Zhifeng Qi,  and Ke Jian Liu
5670-5671
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GDE2/GDPD5 in neuroblastoma

GDE2/GDPD5 in neuroblastoma

https://doi.org/10.18632/oncotarget.14233

Elisa Matas-Rico, Michiel van Veen,  and Wouter H. Moolenaar
5672-5673
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mTOR pathway in familial focal epilepsies

mTOR pathway in familial focal epilepsies

https://doi.org/10.18632/oncotarget.14234

Théo Ribierre,  and Stéphanie Baulac
5674-5675
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Ephrins in astrocytes: synaptic erasers on stage

Ephrins in astrocytes: synaptic erasers on stage

https://doi.org/10.18632/oncotarget.14237

Barbara Di Benedetto
5676-5677
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Molecular rescue of Tsc1-ablated cortical tuber mice

Molecular rescue of Tsc1-ablated cortical tuber mice

https://doi.org/10.18632/oncotarget.14239

Barbara Robens,  and Albert J. Becker
5678-5679
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Myelinating cells can feel disturbances in the force

Myelinating cells can feel disturbances in the force

https://doi.org/10.18632/oncotarget.14240

Yannick Poitelon, Gustavo Della-Flora Nunes,  and M. Laura Feltri
5680-5681
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Environment as therapy: neuroscience for intellectual disability and dementia

Environment as therapy: neuroscience for intellectual disability and dementia

https://doi.org/10.18632/oncotarget.14602

Gabriele Sansevero,  and Alessandro Sale
5682-5683
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Assessing alcohol and nicotine co-consumption in mice

Assessing alcohol and nicotine co-consumption in mice

https://doi.org/10.18632/oncotarget.14603

Jillienne C. Touchette,  and Anna M. Lee
5684-5685
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Research Perspectives

Autophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors

Autophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors

https://doi.org/10.18632/oncotarget.13892

Guido Kroemer,  and Lorenzo Galluzzi
5686-5691
Abstract  |  PDF  |  HTML  |  How to cite

Research Papers: Pathology

Significant association between functional microRNA polymorphisms and coronary heart disease susceptibility: a comprehensive meta-analysis involving 16484 subjects

Significant association between functional microRNA polymorphisms and coronary heart disease susceptibility: a comprehensive meta-analysis involving 16484 subjects

https://doi.org/10.18632/oncotarget.14249

Xu Liu, Lianghao You, Ruizhi Zhou,  and Jian Zhang
5692-5702
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Research Papers

Immunotherapy for patients with advanced pancreatic carcinoma: a promising treatment

Immunotherapy for patients with advanced pancreatic carcinoma: a promising treatment

https://doi.org/10.18632/oncotarget.13968

Bin Zhang, Yuhao Dong, Jing Liu, Zhouyang Lian, Long Liang, Wenbo Chen, Xiaoning Luo, Shufang Pei, Xiaokai Mo, Lu Zhang, Wenhui Huang, Fusheng Ouyang, Baoliang Guo, Changhong Liang,  and Shuixing Zhang
5703-5716
Abstract  |  PDF  |  HTML  |  How to cite

Hormophysa triquerta polyphenol, an elixir that deters CXCR4- and COX2-dependent dissemination destiny of treatment-resistant pancreatic cancer cells

Hormophysa triquerta polyphenol, an elixir that deters CXCR4- and COX2-dependent dissemination destiny of treatment-resistant pancreatic cancer cells

https://doi.org/10.18632/oncotarget.13900

Sheeja Aravindan, Satishkumar Ramraj, Kathiresan Kandasamy, Somasundaram S. Thirugnanasambandan, Dinesh Babu Somasundaram, Terence S. Herman,  and Natarajan Aravindan
5717-5734
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Sp1-mediated transcriptional activation of miR-205 promotes radioresistance in esophageal squamous cell carcinoma

Sp1-mediated transcriptional activation of miR-205 promotes radioresistance in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.13902

Fei Pan, Hui Mao, Fangfang Bu, Xin Tong, Jingjing Li, Sujie Zhang, Xing Liu, Lingxiong Wang, Liangliang Wu, Rui Chen, Huafeng Wei, Bohua Li, Cheng Li, Yunsheng Yang, Clifford J. Steer, Jian Zhao,  and Yajun Guo
5735-5752
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Early detection of rheumatoid arthritis in rats and humans with 99mTc-3PRGD2 scintigraphy: imaging synovial neoangiogenesis

Early detection of rheumatoid arthritis in rats and humans with 99mTc-3PRGD2 scintigraphy: imaging synovial neoangiogenesis

https://doi.org/10.18632/oncotarget.13953

Yu Wu, Guojian Zhang, Xiangcheng Wang, Zhenfang Zhao, Tao Wang, Xuemei Wang,  and Xiao-Feng Li
5753-5760
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Genomic binding of PAX8-PPARG fusion protein regulates cancer-related pathways and alters the immune landscape of thyroid cancer

Genomic binding of PAX8-PPARG fusion protein regulates cancer-related pathways and alters the immune landscape of thyroid cancer

https://doi.org/10.18632/oncotarget.14050

Yanxiao Zhang, Jingcheng Yu, Vladimir Grachtchouk, Tingting Qin, Carey N. Lumeng, Maureen A. Sartor,  and Ronald J. Koenig
5761-5773
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

RHCG and TCAF1 promoter hypermethylation predicts biochemical recurrence in prostate cancer patients treated by radical prostatectomy

RHCG and TCAF1 promoter hypermethylation predicts biochemical recurrence in prostate cancer patients treated by radical prostatectomy

https://doi.org/10.18632/oncotarget.14391

Siri H. Strand, Michal Switnicki, Mia Moller, Christa Haldrup, Tine M. Storebjerg, Jakob Hedegaard, Iver Nordentoft, Soren Hoyer, Michael Borre, Jakob S. Pedersen, Peter J. Wild, Jong Y. Park, Torben F. Orntoft,  and Karina D. Sorensen
5774-5788
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Decreased TCL6 expression is associated with poor prognosis in patients with clear cell renal cell carcinoma

Decreased TCL6 expression is associated with poor prognosis in patients with clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.11011

Hengchuan Su, Tiantian Sun, Hongkai Wang, Guohai Shi, Hailiang Zhang, Fukang Sun,  and Dingwei Ye
5789-5799
Abstract  |  PDF  |  HTML  |  How to cite

Cucurbitacin B exerts anti-cancer activities in human multiple myeloma cells in vitro and in vivo by modulating multiple cellular pathways

Cucurbitacin B exerts anti-cancer activities in human multiple myeloma cells in vitro and in vivo by modulating multiple cellular pathways

https://doi.org/10.18632/oncotarget.10584

Tai Yang, Jin Liu, Mali Yang, Ning Huang, Yueling Zhong, Ting Zeng, Rong Wei, Zhongjun Wu, Cui Xiao, Xiaohua Cao, Minhui Li, Limei Li, Bin Han, Xiaoping Yu, Hua Li,  and Qiang Zou
5800-5813
Abstract  |  PDF  |  HTML  |  How to cite

Association between Retinoic acid receptor-β hypermethylation and NSCLC risk: a meta-analysis and literature review

Association between Retinoic acid receptor-β hypermethylation and NSCLC risk: a meta-analysis and literature review

https://doi.org/10.18632/oncotarget.14023

Yan Li, De-guo Lu, Ying-mei Ma,  and Hongxiang Liu
5814-5822
Abstract  |  PDF  |  HTML  |  How to cite

ErbB2 inhibition by lapatinib promotes degradation of mutant p53 protein in cancer cells

ErbB2 inhibition by lapatinib promotes degradation of mutant p53 protein in cancer cells

https://doi.org/10.18632/oncotarget.12878

Dun Li,  and Natalia D. Marchenko
5823-5833
Abstract  |  PDF  |  HTML  |  How to cite

Noninvasive amide proton transfer magnetic resonance imaging in evaluating the grading and cellularity of gliomas

Noninvasive amide proton transfer magnetic resonance imaging in evaluating the grading and cellularity of gliomas

https://doi.org/10.18632/oncotarget.13970

Yan Bai, Yusong Lin, Wei Zhang, Lingfei Kong, Lifu Wang, Panli Zuo, Ignacio Vallines, Benjamin Schmitt, Jie Tian, Xiaolei Song, Jinyuan Zhou,  and Meiyun Wang
5834-5842
Abstract  |  PDF  |  HTML  |  How to cite

Improved clinical outcomes of patients with ovarian carcinoma arising in endometriosis

Improved clinical outcomes of patients with ovarian carcinoma arising in endometriosis

https://doi.org/10.18632/oncotarget.13967

Jiaqi Lu, Xiang Tao, Jiayi Zhou, Yingying Lu, Zehua Wang, Haiou Liu,  and Congjian Xu
5843-5852
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Ablation of hepatic malignant tumors with irreversible electroporation: A systematic review and meta-analysis of outcomes

Ablation of hepatic malignant tumors with irreversible electroporation: A systematic review and meta-analysis of outcomes

https://doi.org/10.18632/oncotarget.14030

Guo Tian, Qiyu Zhao, Fen Chen, Tian’an Jiang,  and Weilin Wang
5853-5860
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Total DNA input is a crucial determinant of the sensitivity of plasma cell-free DNA EGFR mutation detection using droplet digital PCR

Total DNA input is a crucial determinant of the sensitivity of plasma cell-free DNA EGFR mutation detection using droplet digital PCR

https://doi.org/10.18632/oncotarget.14390

Yu Zhang, Yan Xu, Wei Zhong, Jing Zhao, Minjiang Chen, Li Zhang, Longyun Li,  and Mengzhao Wang
5861-5873
Abstract  |  PDF  |  HTML  |  How to cite

Novel multiple tyrosine kinase inhibitor ponatinib inhibits bFGF-activated signaling in neuroblastoma cells and suppresses neuroblastoma growth in vivo

Novel multiple tyrosine kinase inhibitor ponatinib inhibits bFGF-activated signaling in neuroblastoma cells and suppresses neuroblastoma growth in vivo

https://doi.org/10.18632/oncotarget.11580

Haoyu Li, Yongfeng Wang, Zhenghu Chen, Jiaxiong Lu, Jessie Pan, Yang Yu, Yanling Zhao, Huiyuan Zhang, Ting Hu, Qing Liu,  and Jianhua Yang
5874-5884
Abstract  |  PDF  |  HTML  |  How to cite

A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts

A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts

https://doi.org/10.18632/oncotarget.11809

Malachia Hoover, Yvess Adamian, Mark Brown, Ali Maawy, Alexander Chang, Jacqueline Lee, Armen Gharibi, Matthew H. Katz, Jason Fleming, Robert M. Hoffman, Michael Bouvet, Robert Doebler,  and Jonathan A. Kelber
5885-5894
Abstract  |  PDF  |  HTML  |  How to cite  |  Press Release  |  Podcast  |  Video Interview

Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells

Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells

https://doi.org/10.18632/oncotarget.13927

Valentina Salvestrini, Stefania Orecchioni, Giovanna Talarico, Francesca Reggiani, Cristina Mazzetti, Francesco Bertolini, Elisa Orioli, Elena Adinolfi, Francesco Di Virgilio, Annalisa Pezzi, Michele Cavo, Roberto M Lemoli,  and Antonio Curti
5895-5908
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Gankyrin promotes epithelial-mesenchymal transition and metastasis in NSCLC through forming a closed circle with IL-6/ STAT3 and TGF-β/SMAD3 signaling pathway

Gankyrin promotes epithelial-mesenchymal transition and metastasis in NSCLC through forming a closed circle with IL-6/ STAT3 and TGF-β/SMAD3 signaling pathway

https://doi.org/10.18632/oncotarget.13947

Wu-ping Wang, Ying Sun, Qiang Lu, Jin-bo Zhao, Xue-jiao Wang, Zhao Chen, Yun-feng Ni, Ju-zheng Wang, Yong Han, Zhi-pei Zhang, Xiao-long Yan,  and Xiao-fei Li
5909-5923
Abstract  |  PDF  |  HTML  |  How to cite

Minimal residual disease after transplantation or lenalidomide-based consolidation in myeloma patients: a prospective analysis

Minimal residual disease after transplantation or lenalidomide-based consolidation in myeloma patients: a prospective analysis

https://doi.org/10.18632/oncotarget.12641

Stefania Oliva, Manuela Gambella, Milena Gilestro, Vittorio Emanuele Muccio, Francesca Gay, Daniela Drandi, Simone Ferrero, Roberto Passera, Chiara Pautasso, Annalisa Bernardini, Mariella Genuardi, Francesca Patriarca, Elona Saraci, Maria Teresa Petrucci, Norbert Pescosta, Anna Marina Liberati, Tommaso Caravita, Concetta Conticello, Alberto Rocci, Pellegrino Musto, Mario Boccadoro, Antonio Palumbo,  and Paola Omedè
5924-5935
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Lycium barbarum polysaccharides inhibit proliferation and migration of bladder cancer cell lines BIU87 by suppressing Pi3K/AKT pathway

Lycium barbarum polysaccharides inhibit proliferation and migration of bladder cancer cell lines BIU87 by suppressing Pi3K/AKT pathway

https://doi.org/10.18632/oncotarget.13963

Xian-Jun Zhang, Hong-Yuan Yu, Yong-jian Cai,  and Mang Ke
5936-5942
Abstract  |  PDF  |  HTML  |  How to cite

Myostatin-deficiency in mice increases global gene expression at the Dlk1-Dio3 locus in the skeletal muscle

Myostatin-deficiency in mice increases global gene expression at the Dlk1-Dio3 locus in the skeletal muscle

https://doi.org/10.18632/oncotarget.13966

Keisuke Hitachi,  and Kunihiro Tsuchida
5943-5953
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Low-dose bortezomib increases the expression of NKG2D and DNAM-1 ligands and enhances induced NK and γδ T cell-mediated lysis in multiple myeloma

Low-dose bortezomib increases the expression of NKG2D and DNAM-1 ligands and enhances induced NK and γδ T cell-mediated lysis in multiple myeloma

https://doi.org/10.18632/oncotarget.13979

Chao Niu, Haofan Jin, Min Li, Shan Zhu, Lei Zhou, Feng Jin, Yulai Zhou, Dongsheng Xu, Jianting Xu, Lianjing Zhao, Shanshan Hao, Wei Li,  and Jiuwei Cui
5954-5964
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Serine protease inhibitor kazal-type 6 inhibits tumorigenesis of human hepatocellular carcinoma cells via its extracellular action

Serine protease inhibitor kazal-type 6 inhibits tumorigenesis of human hepatocellular carcinoma cells via its extracellular action

https://doi.org/10.18632/oncotarget.13983

Kuikui Ge, Jinjiang Huang, Wei Wang, Meigang Gu, Xinchuan Dai, Yuqiang Xu, Hongyu Wu, Guodong Li, Hairong Lu, Jiang Zhong,  and Qingshan Huang
5965-5975
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

STC2 promotes head and neck squamous cell carcinoma metastasis through modulating the PI3K/AKT/Snail signaling

STC2 promotes head and neck squamous cell carcinoma metastasis through modulating the PI3K/AKT/Snail signaling

https://doi.org/10.18632/oncotarget.13355

Shuwen Yang, Qinghai Ji, Bin Chang, Yan Wang, Yongxue Zhu, Duanshu Li, Caiping Huang, Yulong Wang, Guohua Sun, Ling Zhang, Qing Guan, Jun Xiang, Wenjun Wei, Zhongwu Lu, Tian Liao, Jiao Meng, Ziliang Wang, Ben Ma, Li Zhou, Yu Wang,  and Gong Yang
5976-5991
Abstract  |  PDF  |  HTML  |  How to cite

RICTOR amplification identifies a subgroup in small cell lung cancer and predicts response to drugs targeting mTOR

RICTOR amplification identifies a subgroup in small cell lung cancer and predicts response to drugs targeting mTOR

https://doi.org/10.18632/oncotarget.13362

Nneha Sakre, Gary Wildey, Mohadese Behtaj, Adam Kresak, Michael Yang, Pingfu Fu,  and Afshin Dowlati
5992-6002
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Clinicopathological and prognostic significance of COX-2 immunohistochemical expression in breast cancer: a meta-analysis

Clinicopathological and prognostic significance of COX-2 immunohistochemical expression in breast cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.13990

Feng Xu, Mengxin Li, Chao Zhang, Jianxiu Cui, Jun Liu, Jie Li,  and Hongchuan Jiang
6003-6012
Abstract  |  PDF  |  HTML  |  How to cite

Common profiles of Notch signaling differentiate disease-free survival in luminal type A and triple negative breast cancer

Common profiles of Notch signaling differentiate disease-free survival in luminal type A and triple negative breast cancer

https://doi.org/10.18632/oncotarget.13451

Magdalena Orzechowska, Dorota Jędroszka,  and Andrzej K. Bednarek
6013-6032
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Sublobar resection is associated with improved outcomes over radiotherapy in the management of high-risk elderly patients with Stage I non-small cell lung cancer: a systematic review and meta-analysis

Sublobar resection is associated with improved outcomes over radiotherapy in the management of high-risk elderly patients with Stage I non-small cell lung cancer: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.14010

Huan-Huan Wang, Chun-Ze Zhang, Bai-Lin Zhang, Jie Chen, Xian-Liang Zeng, Lei Deng,  and Mao-Bin Meng
6033-6042
Abstract  |  PDF  |  HTML  |  How to cite

A mononucleotide repeat in PRRT2 is an important, frequent target of mismatch repair deficiency in cancer

A mononucleotide repeat in PRRT2 is an important, frequent target of mismatch repair deficiency in cancer

https://doi.org/10.18632/oncotarget.13464

Inês Teles Alves, David Cano, René Böttcher, Hetty van der Korput, Winand Dinjens, Guido Jenster,  and Jan Trapman
6043-6056
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Preclinical evaluation of the PARP inhibitor BMN-673 for the treatment of ovarian clear cell cancer

Preclinical evaluation of the PARP inhibitor BMN-673 for the treatment of ovarian clear cell cancer

https://doi.org/10.18632/oncotarget.14011

Paul M Wilkerson, Konstantin J Dedes, Eleftherios Pierre Samartzis, Ioannis Dedes, Maryou B Lambros, Rachael Natrajan, Arnaud Gauthier, Salvatore Piscuoglio, Chantal Töpfer, Vesna Vukovic, Frances Daley, Britta Weigelt,  and Jorge S Reis-Filho
6057-6066
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

MBD3 inhibits formation of liver cancer stem cells

MBD3 inhibits formation of liver cancer stem cells

https://doi.org/10.18632/oncotarget.13496

Ruizhi Li, Qihua He, Shuo Han, Mingzhi Zhang, Jinwen Liu, Ming Su, Shiruo Wei, Xuan Wang,  and Li Shen
6067-6078
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Methicillin-resistant Staphylococcus aureus isolates in a hospital of Shanghai

Methicillin-resistant Staphylococcus aureus isolates in a hospital of Shanghai

https://doi.org/10.18632/oncotarget.14036

Xiaoguang Wang, Lin Ouyang, Lingfei Luo, Jiqian Liu, Chiping Song, Cuizhen Li, Hongjing Yan,  and Ping Wang
6079-6084
Abstract  |  PDF  |  HTML  |  How to cite

Genome-wide methylation sequencing of paired primary and metastatic cell lines identifies common DNA methylation changes and a role for EBF3 as a candidate epigenetic driver of melanoma metastasis

Genome-wide methylation sequencing of paired primary and metastatic cell lines identifies common DNA methylation changes and a role for EBF3 as a candidate epigenetic driver of melanoma metastasis

https://doi.org/10.18632/oncotarget.14042

Aniruddha Chatterjee, Peter A Stockwell, Antonio Ahn, Euan J Rodger, Anna L Leichter,  and Michael R Eccles
6085-6101

Idelalisib induces PUMA-dependent apoptosis in colon cancer cells

Idelalisib induces PUMA-dependent apoptosis in colon cancer cells

https://doi.org/10.18632/oncotarget.14043

Shida Yang, Zhiyong Zhu, Xiaobing Zhang, Ning Zhang,  and Zhicheng Yao
6102-6113
Abstract  |  PDF  |  HTML  |  How to cite

PRKAR2B plays an oncogenic role in the castration-resistant prostate cancer

PRKAR2B plays an oncogenic role in the castration-resistant prostate cancer

https://doi.org/10.18632/oncotarget.14044

Jianjun Sha, Wei Xue, Baijun Dong, Jiahua Pan, Xiaorong WU, Dong Li, Dongming Liu,  and Yiran Huang
6114-6129
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Tonsillar CD56brightNKG2A+ NK cells restrict primary Epstein-Barr virus infection in B cells via IFN-γ

Tonsillar CD56brightNKG2A+ NK cells restrict primary Epstein-Barr virus infection in B cells via IFN-γ

https://doi.org/10.18632/oncotarget.14045

Aurelia Jud, Monika Kotur, Christoph Berger, Claudine Gysin, David Nadal,  and Anna Lünemann
6130-6141
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Dysregulated miR34a/diacylglycerol kinase ζ interaction enhances T-cell activation in acquired aplastic anemia

Dysregulated miR34a/diacylglycerol kinase ζ interaction enhances T-cell activation in acquired aplastic anemia

https://doi.org/10.18632/oncotarget.14046

Yuan-xin Sun, Hui Li, Qi Feng, Xin Li, Ying-yi Yu, Li-wei Zhou, Yan Gao, Guosheng Li, Juan Ren, Chun-hong Ma, Cheng-jiang Gao,  and Jun Peng
6142-6154
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression

PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression

https://doi.org/10.18632/oncotarget.14047

Ina Hohensee, Han-Ning Chuang, Astrid Grottke, Stefan Werner, Alexander Schulte, Stefan Horn, Katrin Lamszus, Kai Bartkowiak, Isabell Witzel, Manfred Westphal, Jakob Matschke, Markus Glatzel, Manfred Jücker, Tobias Pukrop, Klaus Pantel,  and Harriet Wikman
6155-6168
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Down-regulation of CITED2 attenuates breast tumor growth, vessel formation and TGF-β-induced expression of VEGFA

Down-regulation of CITED2 attenuates breast tumor growth, vessel formation and TGF-β-induced expression of VEGFA

https://doi.org/10.18632/oncotarget.14048

Swaathi Jayaraman, Michele Doucet,  and Scott L. Kominsky
6169-6178
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors

Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors

https://doi.org/10.18632/oncotarget.14049

Shu Feng, Longjiang Shao, Patricia Castro, Ilsa Coleman, Peter S. Nelson, Paul D Smith, Barry R Davies,  and Michael Ittmann
6179-6192
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

The tumor-associated YB-1 protein: new player in the circadian control of cell proliferation

The tumor-associated YB-1 protein: new player in the circadian control of cell proliferation

https://doi.org/10.18632/oncotarget.14051

Cristina Pagano, Orsola di Martino, Gennaro Ruggiero, Andrea Maria Guarino, Nathalie Mueller, Rima Siauciunaite, Markus Reischl, Nicholas Simon Foulkes, Daniela Vallone,  and Viola Calabro
6193-6205
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Similar outcomes between adenoid cystic carcinoma of the breast and invasive ductal carcinoma: a population-based study from the SEER 18 database

Similar outcomes between adenoid cystic carcinoma of the breast and invasive ductal carcinoma: a population-based study from the SEER 18 database

https://doi.org/10.18632/oncotarget.14052

Qing-Xia Chen, Jun-Jing Li, Xiao-Xiao Wang, Pei-Yang Lin, Jie Zhang, Chuan-Gui Song,  and Zhi-Ming Shao
6206-6215
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A common CD55 rs2564978 variant is associated with the susceptibility of non-small cell lung cancer

A common CD55 rs2564978 variant is associated with the susceptibility of non-small cell lung cancer

https://doi.org/10.18632/oncotarget.14053

Yanyan Zhang, Zhi Zhang, Lei Cao, Jia Lin, Zhenbang Yang,  and Xuemei Zhang
6216-6221
Abstract  |  PDF  |  HTML  |  How to cite

A comparison of the clinicopathological features and prognoses of the classical and the tall cell variant of papillary thyroid cancer: a meta-analysis

A comparison of the clinicopathological features and prognoses of the classical and the tall cell variant of papillary thyroid cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.14055

Zeming Liu, Wen Zeng, Tianwen Chen, Yawen Guo, Chao Zhang, Chunping Liu,  and Tao Huang
6222-6232
Abstract  |  PDF  |  HTML  |  How to cite

Protective effects of resveratrol against mancozeb induced apoptosis damage in mouse oocytes

Protective effects of resveratrol against mancozeb induced apoptosis damage in mouse oocytes

https://doi.org/10.18632/oncotarget.14056

Yu LIU, Ya-Long WANG, Shu-wen HE, Ming-Huang CHEN, Zhen ZHANG, Xian-Pei FU, Bin-Bin FU, Bao-Qiong LIAO, Yan-Hong LIN, Zhong-Quan Qi,  and Hai-Long Wang
6233-6245
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

MARCKS protein overexpression in inflammatory breast cancer

MARCKS protein overexpression in inflammatory breast cancer

https://doi.org/10.18632/oncotarget.14057

Maroua Manai, Jeanne Thomassin-Piana, Amor Gamoudi, Pascal Finetti, Marc Lopez, Radhia Eghozzi, Sinda Ayadi, Olfa Ben Lamine, Mohamed Manai, Khaled Rahal, Emmanuelle Charafe-Jauffret, Jocelyne Jacquemier, Patrice Viens, Daniel Birnbaum, Hamouda Boussen, Max Chaffanet,  and François Bertucci
6246-6257
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Precise integrin-targeting near-infrared imaging-guided surgical method increases surgical qualification of peritoneal carcinomatosis from gastric cancer in mice

Precise integrin-targeting near-infrared imaging-guided surgical method increases surgical qualification of peritoneal carcinomatosis from gastric cancer in mice

https://doi.org/10.18632/oncotarget.14058

Haidong Cheng, Chongwei Chi, Wenting Shang, Sha Rengaowa, Jianxin Cui, Jinzuo Ye, Shixin Jiang, Yamin Mao, Caoting Zeng, Huiping Huo, Lin Chen,  and Jie Tian
6258-6272
Abstract  |  PDF  |  HTML  |  How to cite

Adenosine 5′-monophosphate blocks acetaminophen toxicity by increasing ubiquitination-mediated ASK1 degradation

Adenosine 5′-monophosphate blocks acetaminophen toxicity by increasing ubiquitination-mediated ASK1 degradation

https://doi.org/10.18632/oncotarget.14059

Xiao Yang, Yibei Zhan, Qi Sun, Xi Xu, Yi Kong,  and Jianfa Zhang
6273-6282
Abstract  |  PDF  |  HTML  |  How to cite

Abnormal brain functional connectivity leads to impaired mood and cognition in hyperthyroidism: a resting-state functional MRI study

Abnormal brain functional connectivity leads to impaired mood and cognition in hyperthyroidism: a resting-state functional MRI study

https://doi.org/10.18632/oncotarget.14060

Ling Li, Mengmeng Zhi, Zhenghua Hou, Yuqun Zhang, Yingying Yue,  and Yonggui Yuan
6283-6294
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

BRAF-activated lncRNA predicts gastrointestinal cancer patient prognosis: a meta-analysis

BRAF-activated lncRNA predicts gastrointestinal cancer patient prognosis: a meta-analysis

https://doi.org/10.18632/oncotarget.14061

Yang-Hua Fan, Min-Hua Ye, Lei Wu, Miao-Jing Wu, Shi-Gang Lu,  and Xin-Gen Zhu
6295-6303
Abstract  |  PDF  |  HTML  |  How to cite

mir-218-2 promotes glioblastomas growth, invasion and drug resistance by targeting CDC27

mir-218-2 promotes glioblastomas growth, invasion and drug resistance by targeting CDC27

https://doi.org/10.18632/oncotarget.13850

Zhuoying Feng, Luping Zhang, Junchen Zhou, Shuai Zhou, Li li, Xuyan Guo, Guoying Feng, Ze Ma, Wenhua Huang,  and Fei Huang
6304-6318
Abstract  |  PDF  |  HTML  |  How to cite

Histone deacetylases 1 and 2 cooperate in regulating BRCA1, CHK1, and RAD51 expression in acute myeloid leukemia cells

Histone deacetylases 1 and 2 cooperate in regulating BRCA1, CHK1, and RAD51 expression in acute myeloid leukemia cells

https://doi.org/10.18632/oncotarget.14062

Jianyun Zhao, Chengzhi Xie, Holly Edwards, Guan Wang, Jeffrey W. Taub,  and Yubin Ge
6319-6329
Abstract  |  PDF  |  HTML  |  How to cite

Diagnostic and prognostic value of circulating tumor DNA in gastric cancer: a meta-analysis

Diagnostic and prognostic value of circulating tumor DNA in gastric cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.14064

Yunhe Gao, Kecheng Zhang, Hongqing Xi, Aizhen Cai, Xiaosong Wu, Jianxin Cui, Jiyang Li, Zhi Qiao, Bo Wei,  and Lin Chen
6330-6340
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

In vitro and in vivo anti-leukemic activity of the peptidase-potentiated alkylator melflufen in acute myeloid leukemia

In vitro and in vivo anti-leukemic activity of the peptidase-potentiated alkylator melflufen in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.13856

Sara Strese, Saadia Bashir Hassan, Ebba Velander, Caroline Haglund, Martin Höglund, Rolf Larsson,  and Joachim Gullbo
6341-6352
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma

Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.14087

Kan Tanabe, Yoshinari Shinsato, Tatsuhiko Furukawa, Yoshiaki Kita, Kazuhito Hatanaka, Kentaro Minami, Kohichi Kawahara, Masatatsu Yamamoto, Kenji Baba, Shinichiro Mori, Yasuto Uchikado, Kosei Maemura, Akihide Tanimoto,  and Shoji Natsugoe
6353-6363
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Radiolabeled novel mAb 4G1 for immunoSPECT imaging of EGFRvIII expression in preclinical glioblastoma xenografts

Radiolabeled novel mAb 4G1 for immunoSPECT imaging of EGFRvIII expression in preclinical glioblastoma xenografts

https://doi.org/10.18632/oncotarget.14088

Xujie Liu, Chengyan Dong, Jiyun Shi, Teng Ma, Zhongxia Jin, Bing Jia, Zhaofei Liu, Li Shen,  and Fan Wang
6364-6375
Abstract  |  PDF  |  HTML  |  How to cite

Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism

Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism

https://doi.org/10.18632/oncotarget.14093

Zuzana Rychtarcikova, Sandra Lettlova, Veronika Tomkova, Vlasta Korenkova, Lucie Langerova, Ekaterina Simonova, Polina Zjablovskaja, Meritxell Alberich-Jorda, Jiri Neuzil,  and Jaroslav Truksa
6376-6398
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A novel assay to detect calreticulin mutations in myeloproliferative neoplasms

A novel assay to detect calreticulin mutations in myeloproliferative neoplasms

https://doi.org/10.18632/oncotarget.14113

Valentina Rosso, Jessica Petiti, Enrico Bracco, Roberto Pedrola, Francesca Carnuccio, Elisabetta Signorino, Sonia Carturan, Chiara Calabrese, Giada Bot-Sartor, Michela Ronconi, Anna Serra, Giuseppe Saglio, Francesco Frassoni,  and Daniela Cilloni
6399-6405
Abstract  |  PDF  |  HTML  |  How to cite

Cell-free methylation markers with diagnostic and prognostic potential in hepatocellular carcinoma

Cell-free methylation markers with diagnostic and prognostic potential in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.14115

Chang-Yi Lu, Shih-Ya Chen, Hui-Ling Peng, Pu-Yeh Kan, Wan-Chi Chang,  and Chia-Jui Yen
6406-6418
Abstract  |  PDF  |  HTML  |  How to cite

Autophagy inhibition enhances photocytotoxicity of Photosan-II in human colorectal cancer cells

Autophagy inhibition enhances photocytotoxicity of Photosan-II in human colorectal cancer cells

https://doi.org/10.18632/oncotarget.14117

Li Xiong, Zhipeng Liu, Guoqing Ouyang, Liangwu Lin, He Huang, Hongxiang Kang, Wei Chen, Xiongying Miao,  and Yu Wen
6419-6432
Abstract  |  PDF  |  HTML  |  How to cite

Resistance to glucose starvation as metabolic trait of platinum-resistant human epithelial ovarian cancer cells

Resistance to glucose starvation as metabolic trait of platinum-resistant human epithelial ovarian cancer cells

https://doi.org/10.18632/oncotarget.14118

Anna Pastò, Anna Pagotto, Giorgia Pilotto, Angela De Paoli, Gian Luca De Salvo, Alessandra Baldoni, Maria Ornella Nicoletto, Francesca Ricci, Giovanna Damia, Chiara Bellio, Stefano Indraccolo,  and Alberto Amadori
6433-6445
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Use of non-selective β-blockers is associated with decreased tumor proliferative indices in early stage breast cancer

Use of non-selective β-blockers is associated with decreased tumor proliferative indices in early stage breast cancer

https://doi.org/10.18632/oncotarget.14119

Alexa Montoya, Clarissa N. Amaya, Andres Belmont, Nabih Diab, Richard Trevino, Geri Villanueva, Steven Rains, Luis A. Sanchez, Nabeel Badri, Salman Otoukesh, Ali Khammanivong, Danielle Liss, Sarah T. Baca, Renato J. Aguilera, Erin B. Dickerson, Alireza Torabi, Alok K. Dwivedi, Aamer Abbas, Karinn Chambers, Brad A. Bryan,  and Zeina Nahleh
6446-6460
Abstract  |  PDF  |  HTML  |  How to cite

Activation of ATR-Chk1 pathway facilitates EBV-mediated transformation of primary tonsillar B-cells

Activation of ATR-Chk1 pathway facilitates EBV-mediated transformation of primary tonsillar B-cells

https://doi.org/10.18632/oncotarget.14120

Vanessa Mordasini, Seigo Ueda, Roberta Aslandogmus, Christoph Berger, Claudine Gysin, Daniela Hühn, Alessandro A. Sartori, Michele Bernasconi,  and David Nadal
6461-6474
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Variants in microRNA genes in familial papillary thyroid carcinoma

Variants in microRNA genes in familial papillary thyroid carcinoma

https://doi.org/10.18632/oncotarget.14129

Jerneja Tomsic, Rebecca Fultz, Sandya Liyanarachchi, Luke K. Genutis, Yanqiang Wang, Wei Li, Stefano Volinia, Krystian Jazdzewski, Huiling He, Paul E Wakely Jr., Leigha Senter,  and Albert de la Chapelle
6475-6482
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Recurrent genetic defects on chromosome 5q in myeloid neoplasms

Recurrent genetic defects on chromosome 5q in myeloid neoplasms

https://doi.org/10.18632/oncotarget.14130

Naoko Hosono, Hideki Makishima, Reda Mahfouz, Bartlomiej Przychodzen, Kenichi Yoshida, Andres Jerez, Thomas LaFramboise, Chantana Polprasert, Michael J. Clemente, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Masashi Sanada, Edward Cui, Amit K. Verma, Michael A. McDevit, Alan F. List, Yogen Saunthararajah, Mikkael A. Sekeres, Jacqueline Boultwood, Seishi Ogawa,  and Jaroslaw P. Maciejewski
6483-6495
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

TIMP-1 and CD82, a promising combined evaluation marker for PDAC

TIMP-1 and CD82, a promising combined evaluation marker for PDAC

https://doi.org/10.18632/oncotarget.14133

Jiexin Zhang, Tijun Wu, Shanshan Zhan, Nan Qiao, Xu Zhang, Yunxia Zhu, Nan Yang, Yujie Sun, Xin A. Zhang, David Bleich,  and Xiao Han
6496-6512
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A six-microRNA panel in plasma was identified as a potential biomarker for lung adenocarcinoma diagnosis

A six-microRNA panel in plasma was identified as a potential biomarker for lung adenocarcinoma diagnosis

https://doi.org/10.18632/oncotarget.14311

Xin Zhou, Wei Wen, Xia Shan, Wei Zhu, Jing Xu, Renhua Guo, Wenfang Cheng, Fang Wang, Lian-Wen Qi, Yan Chen, Zebo Huang, Tongshan Wang, Danxia Zhu, Ping Liu,  and Yongqian Shu
6513-6525
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

HER3 and LINC00052 interplay promotes tumor growth in breast cancer

HER3 and LINC00052 interplay promotes tumor growth in breast cancer

https://doi.org/10.18632/oncotarget.14313

Ahmad Salameh, Xuejun Fan, Byung-Kwon Choi, Shu Zhang, Ningyan Zhang,  and Zhiqiang An
6526-6539
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Multiple drug resistance-associated protein (MRP4) exports prostaglandin E2 (PGE2) and contributes to metastasis in basal/triple negative breast cancer

Multiple drug resistance-associated protein (MRP4) exports prostaglandin E2 (PGE2) and contributes to metastasis in basal/triple negative breast cancer

https://doi.org/10.18632/oncotarget.14145

Tyler J. Kochel, Jocelyn C. Reader, Xinrong Ma, Namita Kundu,  and Amy M. Fulton
6540-6554
Abstract  |  PDF  |  HTML  |  How to cite

High expression of the long non-coding RNA HEIRCC promotes Renal Cell Carcinoma metastasis by inducing epithelial-mesenchymal transition

High expression of the long non-coding RNA HEIRCC promotes Renal Cell Carcinoma metastasis by inducing epithelial-mesenchymal transition

https://doi.org/10.18632/oncotarget.14149

Jing Xiong, Ying Liu, Shengjun Luo, Li Jiang, Yang Zeng, Zhixiong Chen, Xiaobo Shi, Bufan Lv,  and Wei Tang
6555-6563
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Targeted delivery of nano-PTX to the brain tumor-associated macrophages

Targeted delivery of nano-PTX to the brain tumor-associated macrophages

https://doi.org/10.18632/oncotarget.14169

Lei Zou, Youhua Tao, Gregory Payne, Linh Do, Tima Thomas, Juan Rodriguez,  and Huanyu Dou
6564-6578
Abstract  |  PDF  |  HTML  |  How to cite

Whole-exome sequencing identified mutational profiles of high-grade colon adenomas

Whole-exome sequencing identified mutational profiles of high-grade colon adenomas

https://doi.org/10.18632/oncotarget.14172

Sung Hak Lee, Seung Hyun Jung, Tae-Min Kim, Je-Keun Rhee, Hyeon-Chun Park, Min Sung Kim, Sung Soo Kim, Sug Hyung Lee, Chang Hyeok An, Sug Hyung Lee,  and Yeun-Jun Chung
6579-6588
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

The long non-coding RNA GAS5 differentially regulates cell cycle arrest and apoptosis through activation of BRCA1 and p53 in human neuroblastoma

The long non-coding RNA GAS5 differentially regulates cell cycle arrest and apoptosis through activation of BRCA1 and p53 in human neuroblastoma

https://doi.org/10.18632/oncotarget.14244

Joseph Mazar, Amy Rosado, John Shelley, John Marchica,  and Tamarah J. Westmoreland
6589-6607
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells

Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells

https://doi.org/10.18632/oncotarget.14245

Hyun-Jung Kim, Soo Yoon Lee, Chan Young Kim, Yun Hwan Kim, Woong Ju,  and Seung Cheol Kim
6608-6622
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Circulating thyroid stimulating hormone receptor messenger RNA and differentiated thyroid cancer: A diagnostic meta-analysis

Circulating thyroid stimulating hormone receptor messenger RNA and differentiated thyroid cancer: A diagnostic meta-analysis

https://doi.org/10.18632/oncotarget.14251

Zhen-Zhen Zhang, Qiang Chen, Chao-Yue Kong, Zhan-Ming Li,  and Li-Shun Wang
6623-6629
Abstract  |  PDF  |  HTML  |  How to cite

Effects of alcohol consumption, ALDH2 rs671 polymorphism, and Helicobacter pylori infection on the gastric cancer risk in a Korean population

Effects of alcohol consumption, ALDH2 rs671 polymorphism, and Helicobacter pylori infection on the gastric cancer risk in a Korean population

https://doi.org/10.18632/oncotarget.14250

Sarah Yang, Jeonghee Lee, Il Ju Choi, Young Woo Kim, Keun Won Ryu, Joohon Sung,  and Jeongseon Kim
6630-6641
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Interactive role of diabetes mellitus and female sex in the risk of cholangiocarcinoma: A population-based nested case–control study

Interactive role of diabetes mellitus and female sex in the risk of cholangiocarcinoma: A population-based nested case–control study

https://doi.org/10.18632/oncotarget.14254

Yan-Jiun Huang, Alexander TH Wu, Hung-Yi Chiou, Ming-Tsang Chuang, Tzu-Ching Meng, Li-Nien Chien,  and Yun Yen
6642-6651
Abstract  |  PDF  |  HTML  |  How to cite

Robust transcriptional tumor signatures applicable to both formalin-fixed paraffin-embedded and fresh-frozen samples

Robust transcriptional tumor signatures applicable to both formalin-fixed paraffin-embedded and fresh-frozen samples

https://doi.org/10.18632/oncotarget.14257

Rou Chen, Qingzhou Guan, Jun Cheng, Jun He, Huaping Liu, Hao Cai, Guini Hong, Jiahui Zhang, Na Li, Lu Ao,  and Zheng Guo
6652-6662
Abstract  |  PDF  |  HTML  |  How to cite

Interleukin-17A promotes tongue squamous cell carcinoma metastasis through activating miR-23b/versican pathway

Interleukin-17A promotes tongue squamous cell carcinoma metastasis through activating miR-23b/versican pathway

https://doi.org/10.18632/oncotarget.14255

Tai Wei, Xin Cong, Xiang-Ting Wang, Xiao-Jian Xu, Sai-Nan Min, Peng Ye, Xin Peng, Li-Ling Wu,  and Guang-Yan Yu
6663-6680
Abstract  |  PDF  |  HTML  |  How to cite

Integrin α6 promotes esophageal cancer metastasis and is targeted by miR-92b

Integrin α6 promotes esophageal cancer metastasis and is targeted by miR-92b

https://doi.org/10.18632/oncotarget.14259

Gang Ma, Chao Jing, Furong Huang, Xukun Li, Xiufeng Cao,  and Zhihua Liu
6681-6690
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Cordycepin induces autophagy-mediated c-FLIPL degradation and leads to apoptosis in human non-small cell lung cancer cells

Cordycepin induces autophagy-mediated c-FLIPL degradation and leads to apoptosis in human non-small cell lung cancer cells

https://doi.org/10.18632/oncotarget.14262

Xinghui Yu, Jianya Ling, Xianfang Liu, Sen Guo, Yidan Lin, Xiangguo Liu,  and Ling Su
6691-6699
Abstract  |  PDF  |  HTML  |  How to cite

Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate

Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate

https://doi.org/10.18632/oncotarget.14265

Anna Merlo, Cristóbal Bernardo-Castiñeira, Inés Sáenz-de-Santa-María, Ana S Pitiot, Milagros Balbín, Aurora Astudillo, Nuria Valdés, Bartolomé Scola, Raquel Del Toro, Simón Méndez-Ferrer, José I Piruat, Carlos Suarez,  and María-Dolores Chiara
6700-6717
Abstract  |  PDF  |  HTML  |  How to cite

Positive feedback loop of IL-1β/Akt/RARα/Akt signaling mediates oncogenic property of RARα in gastric carcinoma

Positive feedback loop of IL-1β/Akt/RARα/Akt signaling mediates oncogenic property of RARα in gastric carcinoma

https://doi.org/10.18632/oncotarget.14267

Hong-Yue Ren, Fan Liu, Gui-Li Huang, Yu Liu, Jin-Xing Shen, Pan Zhou, Wen-Ming Liu,  and Dong-Yan Shen
6718-6729
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models

The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models

https://doi.org/10.18632/oncotarget.14268

Kristian W. Pajtler, Natalie Sadowski, Sandra Ackermann, Kristina Althoff, Kerstin Schönbeck, Katharina Batzke, Simon Schäfers, Andrea Odersky, Lukas Heukamp, Kathy Astrahantseff, Annette Künkele, Hedwig E. Deubzer, Alexander Schramm, Annika Sprüssel, Theresa Thor, Sven Lindner, Angelika Eggert, Matthias Fischer,  and Johannes H. Schulte
6730-6741
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming

CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming

https://doi.org/10.18632/oncotarget.14272

Agnieszka A. Kendrick, Johnathon Schafer, Monika Dzieciatkowska, Travis Nemkov, Angelo D’Alessandro, Deepika Neelakantan, Heide L. Ford, Chad G. Pearson, Colin D. Weekes, Kirk C. Hansen,  and Elan Z. Eisenmesser
6742-6762
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Induction chemotherapy for the treatment of non-endemic locally advanced nasopharyngeal carcinoma

Induction chemotherapy for the treatment of non-endemic locally advanced nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.14279

Lina Zhao, Man Xu, Wen Jiang, Haitao Pan, Jian Zang, Shanquan Luo, Jianhua Wang, Yongchun Zhou,  and Mei Shi
6763-6774
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Comprehensive tissue-specific gene set enrichment analysis and transcription factor analysis of breast cancer by integrating 14 gene expression datasets

Comprehensive tissue-specific gene set enrichment analysis and transcription factor analysis of breast cancer by integrating 14 gene expression datasets

https://doi.org/10.18632/oncotarget.14286

Wen-Xing Li, Kan He, Ling Tang, Shao-Xing Dai, Gong-Hua Li, Wen-Wen Lv, Yi-Cheng Guo, San-Qi An, Guo-Ying Wu, Dahai Liu,  and Jing-Fei Huang
6775-6786
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor

EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor

https://doi.org/10.18632/oncotarget.14290

Mamoru Takada, Ming Zhuang, Hiroyuki Inuzuka, Jing Zhang, Giada Zurlo, Jinfang Zhang,  and Qing Zhang
6787-6795
Abstract  |  PDF  |  HTML  |  How to cite

A novel nonsense mutation in androgen receptor confers resistance to CYP17 inhibitor treatment in prostate cancer

A novel nonsense mutation in androgen receptor confers resistance to CYP17 inhibitor treatment in prostate cancer

https://doi.org/10.18632/oncotarget.14296

Dong Han, Shuai Gao, Kevin Valencia, Jude Owiredu, Wanting Han, Eric de Waal, Jill A. Macoska,  and Changmeng Cai
6796-6808
Abstract  |  PDF  |  HTML  |  How to cite

Pan-organ transcriptome variation across 21 cancer types

Pan-organ transcriptome variation across 21 cancer types

https://doi.org/10.18632/oncotarget.14303

Wangxiong Hu, Yanmei Yang, Xiaofen Li,  and Shu Zheng
6809-6818
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Proteins that interact with calgranulin B in the human colon cancer cell line HCT-116

Proteins that interact with calgranulin B in the human colon cancer cell line HCT-116

https://doi.org/10.18632/oncotarget.14301

Jae Kyung Myung, Seung-Gu Yeo, Kyung Hee Kim, Kwang-Soo Baek, Daye Shin, Jong Heon Kim, Jae Youl Cho,  and Byong Chul Yoo
6819-6832
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

The prognostic value of long noncoding RNA HOTTIP on clinical outcomes in breast cancer

The prognostic value of long noncoding RNA HOTTIP on clinical outcomes in breast cancer

https://doi.org/10.18632/oncotarget.14304

Yinlong Yang, Jinxian Qian, Youqun Xiang, Yizuo Chen,  and Jinmiao Qu
6833-6844
Abstract  |  PDF  |  HTML  |  How to cite

Quantitative assessment of the diagnostic role of FHIT promoter methylation in non-small cell lung cancer

Quantitative assessment of the diagnostic role of FHIT promoter methylation in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.14256

Xin Geng, Weilin Pu, Yulong Tan, Zhouyi Lu, An Wang, Lixing Tan, Sidi Chen, Shicheng Guo, Jiucun Wang,  and Xiaofeng Chen
6845-6856
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

N-glycosylation converts non-glycoproteins into mannose receptor ligands and reveals antigen-specific T cell responses in vivo

N-glycosylation converts non-glycoproteins into mannose receptor ligands and reveals antigen-specific T cell responses in vivo

https://doi.org/10.18632/oncotarget.14314

Christoph Kreer, Janina M. Kuepper, Matthias Zehner, Thomas Quast, Waldemar Kolanus, Beatrix Schumak,  and Sven Burgdorf
6857-6872
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Vitamin D deficiency is associated with a worse prognosis in metastatic melanoma

Vitamin D deficiency is associated with a worse prognosis in metastatic melanoma

https://doi.org/10.18632/oncotarget.14316

Dmitriy Timerman, Melissa McEnery-Stonelake, Cara J. Joyce, Vinod E. Nambudiri, F. Stephen Hodi, Elizabeth B. Claus, Nageatte Ibrahim,  and Jennifer Y. Lin
6873-6882
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Expression of pannexin 1 and 2 in cortical lesions from intractable epilepsy patients with focal cortical dysplasia

Expression of pannexin 1 and 2 in cortical lesions from intractable epilepsy patients with focal cortical dysplasia

https://doi.org/10.18632/oncotarget.14317

Song Li, Zhenle Zang, Jiaojiang He, Xin Chen, Sixun Yu, Yuchun Pei, Zhi Hou, Ning An, Hui Yang, Chunqing Zhang,  and Shiyong Liu
6883-6895
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Assessing the clinical value of microRNAs in formalin-fixed paraffin-embedded liposarcoma tissues: Overexpressed miR-155 is an indicator of poor prognosis

Assessing the clinical value of microRNAs in formalin-fixed paraffin-embedded liposarcoma tissues: Overexpressed miR-155 is an indicator of poor prognosis

https://doi.org/10.18632/oncotarget.14320

Nikolaos Kapodistrias, Konstantinos Mavridis, Anna Batistatou, Penelope Gogou, Vasilios Karavasilis, Ioannis Sainis, Evangelos Briasoulis,  and Andreas Scorilas
6896-6913
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma

Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma

https://doi.org/10.18632/oncotarget.14321

Tiziana Petrachi, Alessandra Romagnani, Adriana Albini, Caterina Longo, Giuseppe Argenziano, Giulia Grisendi, Massimo Dominici, Alessia Ciarrocchi,  and Katiuscia Dallaglio
6914-6928
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

A retrospective study of NENs and miR-224 promotes apoptosis of BON-1 cells by targeting PCSK9 inhibition

A retrospective study of NENs and miR-224 promotes apoptosis of BON-1 cells by targeting PCSK9 inhibition

https://doi.org/10.18632/oncotarget.14322

Jian’an Bai, He Na, Xiumei Hua, Yaling Wei, Tian Ye, Yiqiang Zhang, Guo Jian, Weiwen Zeng, Lijun Yan,  and Qiyun Tang
6929-6939
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas

c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas

https://doi.org/10.18632/oncotarget.14330

Dieter H. Heiland, Roberto Ferrarese, Rainer Claus, Fangping Dai, Anie P. Masilamani, Eva Kling, Astrid Weyerbrock, Teresia Kling, Sven Nelander,  and Maria S. Carro
6940-6954
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Clinical and biological significance of miR-23b and miR-193a in human hepatocellular carcinoma

Clinical and biological significance of miR-23b and miR-193a in human hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.14332

Ilaria Grossi, Bruna Arici, Nazario Portolani, Giuseppina De Petro,  and Alessandro Salvi
6955-6969
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

High expression of miR-181c as a predictive marker of recurrence in stage II colorectal cancer

High expression of miR-181c as a predictive marker of recurrence in stage II colorectal cancer

https://doi.org/10.18632/oncotarget.14344

Nobuyoshi Yamazaki, Yoshikatsu Koga, Hirokazu Taniguchi, Motohiro Kojima, Yukihide Kanemitsu, Norio Saito,  and Yasuhiro Matsumura
6970-6983
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Desuccinylation of pyruvate kinase M2 by SIRT5 contributes to antioxidant response and tumor growth

Desuccinylation of pyruvate kinase M2 by SIRT5 contributes to antioxidant response and tumor growth

https://doi.org/10.18632/oncotarget.14346

Ye Xiangyun, Niu Xiaomin, Gu linping, Xu Yunhua, Li Ziming, Yu Yongfeng, Chen Zhiwei,  and Lu Shun
6984-6993
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Circulating miR-1 as a potential biomarker of doxorubicin-induced cardiotoxicity in breast cancer patients

Circulating miR-1 as a potential biomarker of doxorubicin-induced cardiotoxicity in breast cancer patients

https://doi.org/10.18632/oncotarget.14355

Vagner Oliveira-Carvalho Rigaud, Ludmila R.P. Ferreira, Silvia M. Ayub-Ferreira, Mônica S. Ávila, Sara M.G. Brandão, Fátima D. Cruz, Marília H.H. Santos, Cecilia B.B.V. Cruz, Marco S.L. Alves, Victor S. Issa, Guilherme V. Guimarães, Edécio Cunha-Neto,  and Edimar A. Bocchi
6994-7002
Abstract  |  PDF  |  HTML  |  How to cite

Clinical Research Papers

Phase III randomized trial of autologous cytokine-induced killer cell immunotherapy for newly diagnosed glioblastoma in korea

Phase III randomized trial of autologous cytokine-induced killer cell immunotherapy for newly diagnosed glioblastoma in korea

https://doi.org/10.18632/oncotarget.12273

Doo-Sik Kong, Do-Hyun Nam, Shin-Hyuk Kang, Jae Won Lee, Jong-Hee Chang, Jeong-Hoon Kim, Young-Jin Lim, Young-Cho Koh, Yong-Gu Chung, Jae-Min Kim,  and Choong-Hyun Kim
7003-7013
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Comparative effectiveness of combined therapy inhibiting EGFR and VEGF pathways in patients with advanced non-small-cell lung cancer: a meta-analysis of 16 phase II/III randomized trials

Comparative effectiveness of combined therapy inhibiting EGFR and VEGF pathways in patients with advanced non-small-cell lung cancer: a meta-analysis of 16 phase II/III randomized trials

https://doi.org/10.18632/oncotarget.12294

Yongzhao Zhao, Huixian Wang, Yan Shi, Shangli Cai, Tongwei Wu, Guangyue Yan, Sijin Cheng, Kang Cui, Ying Xi, Xiaolong Qi, Jie Zhang,  and Wang Ma
7014-7024
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: clinical implication for improved colon surveillance

Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: clinical implication for improved colon surveillance

https://doi.org/10.18632/oncotarget.12347

Shiv Ram Krishn, Sukhwinder Kaur, Yuri M. Sheinin, Lynette M. Smith, Shailendra K. Gautam, Asish Patel, Maneesh Jain, Vasthala Juvvigunta, Priya Pai, Audrey J. Lazenby, Hemant K. Roy,  and Surinder K. Batra
7025-7038
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Survival prediction in patients undergoing radionuclide therapy based on intratumoral somatostatin-receptor heterogeneity

Survival prediction in patients undergoing radionuclide therapy based on intratumoral somatostatin-receptor heterogeneity

https://doi.org/10.18632/oncotarget.12402

Rudolf A. Werner, Constantin Lapa, Harun Ilhan, Takahiro Higuchi, Andreas K. Buck, Sebastian Lehner, Peter Bartenstein, Frank Bengel, Imke Schatka, Dirk O. Muegge, László Papp, Norbert Zsótér, Tobias Große-Ophoff, Markus Essler,  and Ralph A. Bundschuh
7039-7049
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Solid predominant histologic subtype and early recurrence predict poor postrecurrence survival in patients with stage I lung adenocarcinoma

Solid predominant histologic subtype and early recurrence predict poor postrecurrence survival in patients with stage I lung adenocarcinoma

https://doi.org/10.18632/oncotarget.12540

Jizhuang Luo, Rui Wang, Baohui Han, Jie Zhang, Heng Zhao, Wentao Fang, Qingquan Luo, Jun Yang, Yunhai Yang, Lei Zhu, Tianxiang Chen, Xinghua Cheng, Qingyuan Huang, Yiyang Wang, Jiajie Zheng,  and Haiquan Chen
7050-7058
Abstract  |  PDF  |  HTML  |  How to cite

Reviews

The IgH 3’ regulatory region and c-myc-induced B-cell lymphomagenesis

The IgH 3’ regulatory region and c-myc-induced B-cell lymphomagenesis

https://doi.org/10.18632/oncotarget.12535

Nour Ghazzaui, Alexis Saintamand, Hussein Issaoui, Christelle Vincent-Fabert,  and Yves Denizot
7059-7067
Abstract  |  PDF  |  HTML  |  How to cite

Advances in sarcoma diagnostics and treatment

Advances in sarcoma diagnostics and treatment

https://doi.org/10.18632/oncotarget.12548

Amanda R. Dancsok, Karama Asleh-Aburaya,  and Torsten O. Nielsen
7068-7093
Abstract  |  PDF  |  HTML  |  How to cite

Stem-like plasticity and heterogeneity of circulating tumor cells: current status and prospect challenges in liver cancer

Stem-like plasticity and heterogeneity of circulating tumor cells: current status and prospect challenges in liver cancer

https://doi.org/10.18632/oncotarget.12569

Margherita Correnti,  and Chiara Raggi
7094-7115
Abstract  |  PDF  |  HTML  |  How to cite

Friend or foe: the dichotomous impact of T cells on neuro-de/re-generation during aging

Friend or foe: the dichotomous impact of T cells on neuro-de/re-generation during aging

https://doi.org/10.18632/oncotarget.12572

Brandon Coder, Weikan Wang, Liefeng Wang, Zhongdao Wu, Qichuan Zhuge,  and Dong-Ming Su
7116-7137
Abstract  |  PDF  |  HTML  |  How to cite

Implications of immune dysfunction on endometriosis associated infertility

Implications of immune dysfunction on endometriosis associated infertility

https://doi.org/10.18632/oncotarget.12577

Jessica E. Miller, Soo Hyun Ahn, Stephany P. Monsanto, Kasra Khalaj, Madhuri Koti,  and Chandrakant Tayade
7138-7147
Abstract  |  PDF  |  HTML  |  How to cite

A meta-analysis on the effect of operation modes on the recurrence of papillary thyroid microcarcinoma

A meta-analysis on the effect of operation modes on the recurrence of papillary thyroid microcarcinoma

https://doi.org/10.18632/oncotarget.12698

Dandan Yi, Peng Song, Tao Huang, Xiaoqiao Tang,  and Jianfeng Sang
7148-7156
Abstract  |  PDF  |  HTML  |  How to cite

Targeting immune checkpoints in malignant glioma

Targeting immune checkpoints in malignant glioma

https://doi.org/10.18632/oncotarget.12702

Xuhao Zhang, Shan Zhu, Tete Li, Yong-Jun Liu, Wei Chen,  and Jingtao Chen
7157-7174
Abstract  |  PDF  |  HTML  |  How to cite

The concept of immune surveillance against tumors: The first theories

The concept of immune surveillance against tumors: The first theories

https://doi.org/10.18632/oncotarget.12739

Domenico Ribatti
7175-7180
Abstract  |  PDF  |  HTML  |  How to cite

Recent development of ATP-competitive small molecule phosphatidylinostitol-3-kinase inhibitors as anticancer agents

Recent development of ATP-competitive small molecule phosphatidylinostitol-3-kinase inhibitors as anticancer agents

https://doi.org/10.18632/oncotarget.12742

Yu Liu, Wen-zhu Wan, Yan Li, Guan-lian Zhou,  and Xin-guang Liu
7181-7200
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Bruton tyrosine kinase inhibitor ONO/GS-4059: from bench to bedside

Bruton tyrosine kinase inhibitor ONO/GS-4059: from bench to bedside

https://doi.org/10.18632/oncotarget.12786

Jingjing Wu, Mingzhi Zhang,  and Delong Liu
7201-7207
Abstract  |  PDF  |  HTML  |  How to cite

Corrections

Correction: MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features

Correction: MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features

https://doi.org/10.18632/oncotarget.14800

Xiaoran Li, Yali Zhong, Jie Lu, Karol Axcrona, Lars Eide, Randi G. Syljuåsen, Qian Peng, Junbai Wang, Hongquan Zhang, Mariusz Adam Goscinski, Gunnar Kvalheim, Jahn M. Nesland,  and Zhenhe Suo
7208-7213
Correction  |  PDF  |  How to cite


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