Indole microbial metabolites: expanding and translating target(s)

Characterization of midostaurin as a dual inhibitor of FLT3 and SYK and potentiation of FLT3 inhibition against FLT3-ITD-driven leukemia harboring activated SYK kinase

Tumor antigen CA125 suppresses antibody-dependent cellular cytotoxicity (ADCC) via direct antibody binding and suppressed Fc-γ receptor engagement

Therapeutic vaccine to cure large mouse hepatocellular carcinomas

5-aza-2’-deoxycytidine (DAC) treatment downregulates the HPV E6 and E7 oncogene expression and blocks neoplastic growth of HPV-associated cancer cells

Quercetin inhibits Cr(VI)-induced malignant cell transformation by targeting miR-21-PDCD4 signaling pathway

Combined CT-guided radiofrequency ablation with systemic chemotherapy improves the survival for nasopharyngeal carcinoma with oligometastasis in liver: Propensity score matching analysis

Analysis of ESR1 and PIK3CA mutations in plasma cell-free DNA from ER-positive breast cancer patients

Lower Beclin 1 downregulates HER2 expression to enhance tamoxifen sensitivity and predicts a favorable outcome for ER positive breast cancer

Hepatic NK cell-mediated hypersensitivity to ConA-induced liver injury in mouse liver expressing hepatitis C virus polyprotein

Association of high microvessel α_vβ₃ and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126

The pseudogene derived long noncoding RNA DUXAP8 promotes gastric cancer cell proliferation and migration via epigenetically silencing PLEKHO1 expression

Nurse-like cells promote CLL survival through LFA-3/CD2 interactions

Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer

Adult T cell leukemia aggressivenness correlates with loss of both 5-hydroxymethylcytosine and TET2 expression

The mTOR inhibitor everolimus in combination with azacitidine in patients with relapsed/refractory acute myeloid leukemia: a phase Ib/II study

The type I insulin-like growth factor regulates the liver stromal response to metastatic colon carcinoma cells

Suppression of microRNA-205-5p in human mesenchymal stem cells improves their therapeutic potential in treating diabetic foot disease

Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis

Oncogenic secretory clusterin in hepatocellular carcinoma: Expression at early staging and emerging molecular target

Positive regulation of TAZ expression by EBV-LMP1 contributes to cell proliferation and epithelial-mesenchymal transition in nasopharyngeal carcinoma

Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor

Prognostic and clinicopathologic significance of SIRT1 expression in hepatocellular carcinoma

Comparisons of short-term and survival outcomes of laparoscopy-assisted versus open total gastrectomy for gastric cancer patients

Galeterone and its analogs inhibit Mnk-eIF4E axis, synergize with gemcitabine, impede pancreatic cancer cell migration, invasion and proliferation and inhibit tumor growth in mice

Expression analysis of microRNA as prognostic biomarkers in colorectal cancer

A phase I trial of azacitidine and nanoparticle albumin bound paclitaxel in patients with advanced or metastatic solid tumors

Unit resection of buccal squamous cell carcinoma: Description of a new surgical technique

CRABP-II enhances pancreatic cancer cell migration and invasion by stabilizing interleukin 8 expression

Eribulin alone or in combination with the PLK1 inhibitor BI 6727 triggers intrinsic apoptosis in Ewing sarcoma cell lines

Prognostic role of podocalyxin-like protein expression in various cancers: A systematic review and meta-analysis

MiR-199a-3p suppresses proliferation and invasion of prostate cancer cells by targeting Smad1

Whole tumor RNA-sequencing and deconvolution reveal a clinically-prognostic PTEN/PI3K-regulated glioma transcriptional signature

Prostate-derived ETS factor improves prognosis and represses proliferation and invasion in hepatocellular carcinoma

Excessive matrix metalloprotease-mediated degradation of interstitial tissue (type I collagen) independently predicts short-term survival in an observational study of postmenopausal women diagnosed with cancer

Api5 a new cofactor of estrogen receptor alpha involved in breast cancer outcome

Effects of microRNA-126 on cell proliferation, apoptosis and tumor angiogenesis via the down-regulating ERK signaling pathway by targeting EGFL7 in hepatocellular carcinoma

New in vivo avatars of diffuse intrinsic pontine gliomas (DIPG) from stereotactic biopsies performed at diagnosis

Hepatitis B virus surface proteins accelerate cholestatic injury and tumor progression in Abcb4-knockout mice

Integrated expression profiles analysis reveals novel predictive biomarker in pancreatic ductal adenocarcinoma

siRNA-mediated inactivation of HER3 improves the antitumour activity and sensitivity of gefitinib in gastric cancer cells

Intercellular adhesion molecule 1 rs5498 polymorphism is associated with the risk of myocardial infarction

Identification of long non-coding RNAs biomarkers associated with progression of endometrial carcinoma and patient outcomes

MM-BMSCs induce naïve CD4+ T lymphocytes dysfunction through fibroblast activation protein α

Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens

Suppression of pyruvate dehydrogenase kinase-2 re-sensitizes paclitaxel-resistant human lung cancer cells to paclitaxel

Combination treatment with transarterial chemoembolization, radiotherapy, and hyperthermia (CERT) for hepatocellular carcinoma with portal vein tumor thrombosis: Final results of a prospective phase II trial

Prognostic value of Flotillin-1 expression in patients with solid tumors

Transcription factor c-Rel is indispensable for generation of thymic but not of peripheral Foxp3+ regulatory T cells

Erectile dysfunction and the risk of prostate cancer

TBX2 over-expression promotes nasopharyngeal cancer cell proliferation and invasion

Detection of nasopharyngeal carcinoma susceptibility with single nucleotide polymorphism analysis using next-generation sequencing technology

Mitral isthmus ablation using a circular mapping catheter positioned in the left atrial appendage as a reference for conduction block

NFATc3 mediates the sensitivity of gastric cancer cells to arsenic sulfide

Transgenic overexpression of NanogP8 in the mouse prostate is insufficient to initiate tumorigenesis but weakly promotes tumor development in the Hi-Myc mouse model

Downregulated long noncoding RNA ALDBGALG0000005049 induces inflammation in chicken muscle suffered from selenium deficiency by regulating stearoyl-CoA desaturase

Middle-distance running acutely influences the concentration and composition of serum bile acids: Potential implications for cancer risk?

Toxicarioside O induces protective autophagy in a sirtuin-1-dependent manner in colorectal cancer cells

Prediction of EGFR and KRAS mutation in non-small cell lung cancer using quantitative ¹⁸F FDG-PET/CT metrics

High-resolution dynamic imaging and quantitative analysis of lung cancer xenografts in nude mice using clinical PET/CT

Apatinib inhibits VEGFR-2 and angiogenesis in an in vivo murine model of nasopharyngeal carcinoma

Chromatin remodeling modulates radiosensitivity of the daughter cells derived from cell population exposed to low- and high-LET irradiation

Uridine diphosphate-glucuronosyltransferase 2B15 D85Y gene polymorphism is associated with lower prostate cancer risk: a systematic review and meta-analysis

Changing trends in the prevalence of anencephaly in Liaoning province of Northeast China from 2006–2015: data from a population-based birth defects registry

OVA12 promotes tumor growth by regulating p53 expression in human cancer cells

Treatment of hepatocellular carcinoma with a GPC3-targeted bispecific T cell engager

The anti-ErbB2 antibody H2-18 and the pan-PI3K inhibitor GDC-0941 effectively inhibit trastuzumab-resistant ErbB2-overexpressing breast cancer

PD-L1: a novel prognostic biomarker in head and neck squamous cell carcinoma

Twist1 confers multidrug resistance in colon cancer through upregulation of ATP-binding cassette transporters

miR-106b regulates the 5-fluorouracil resistance by targeting Zbtb7a in cholangiocarcinoma

Effect and mechanism of inhibition of PI3K/Akt/mTOR signal pathway on chronic neuropathic pain and spinal microglia in a rat model of chronic constriction injury

Selective Inhibitors of Nuclear Export (SINE) compounds block proliferation and migration of triple negative breast cancer cells by restoring expression of ARRDC3

MiR-486-5p negatively regulates oncogenic NEK2 in hepatocellular carcinoma

TUSC3 induces autophagy in human non-small cell lung cancer cells through Wnt/β-catenin signaling

Mitochondrial DNA sequencing and large-scale genotyping identifies MT-ND4 gene mutation m.11696G>A associated with idiopathic oligoasthenospermia

miR-133b down-regulates ABCC1 and enhances the sensitivity of CRC to anti-tumor drugs

Pulmonary endothelial cell DNA methylation signature in pulmonary arterial hypertension

MicroRNA profiles involved in trifluridine resistance

Dipeptidyl peptidase 4 inhibitor use is associated with a lower risk of incident acute kidney injury in patients with diabetes

Long working hours, job satisfaction, and depressive symptoms: a community-based cross-sectional study among Japanese employees in small- and medium-scale businesses

Lenalidomide increases human dendritic cell maturation in multiple myeloma patients targeting monocyte differentiation and modulating mesenchymal stromal cell inhibitory properties

Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN

RNase alleviates neurological dysfunction in mice undergoing cardiac arrest and cardiopulmonary resuscitation

Discriminating patients with early-stage breast cancer from benign lesions by detection of oxidative DNA damage biomarker in urine

Upregulation of long noncoding RNA HOXA-AS3 promotes tumor progression and predicts poor prognosis in glioma

Role of A-Kinase anchor protein (AKAP4) in growth and survival of ovarian cancer cells

Prognostic values of tissue factor and its alternatively splice transcripts in human gastric cancer tissues

Menstrual pattern after abdominal radical trachelectomy

A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer

MEK inhibition enhances efficacy of bacillus Calmette-Guérin on bladder cancer cells by reducing release of Toll-like receptor 2-activated antimicrobial peptides

Regulation of actin-binding protein ANLN by antitumor miR-217 inhibits cancer cell aggressiveness in pancreatic ductal adenocarcinoma

Altered erythropoiesis and decreased number of erythrocytes in children with neuroblastoma

Down regulation of human positive coactivator 4 suppress tumorigenesis and lung metastasis of osteosarcoma

Increased p16 and p53 protein expression predicts poor prognosis in mucosal melanoma

Associations of high altitude polycythemia with polymorphisms in EPHA2 and AGT in Chinese Han and Tibetan populations

CXCL13 is androgen-responsive and involved in androgen induced prostate cancer cell migration and invasion

Jagged-2 (JAG2) enhances tumorigenicity and chemoresistance of colorectal cancer cells

Infiltrating macrophages in diabetic nephropathy promote podocytes apoptosis via TNF-α-ROS-p38MAPK pathway

AKT can modulate the in vitro response of HNSCC cells to irreversible EGFR inhibitors

A combination of valproic acid sodium salt, CHIR99021, E-616452, tranylcypromine, and 3-Deazaneplanocin A causes stem cell-like characteristics in cancer cells

Differential metabonomic profiles of primary hepatocellular carcinoma tumors from alcoholic liver disease, HBV-infected, and HCV-infected cirrhotic patients

Diagnostic and prognostic values of cerebrospinal fluid CYFRA 21-1 in patients with leptomeningeal carcinomatosis

Clinicopathological characteristics of ROS1- and RET-rearranged NSCLC in caucasian patients: Data from a cohort of 713 non-squamous NSCLC lacking KRAS/EGFR/HER2/BRAF/PIK3CA/ALK alterations

Autophagy-related genes are induced by histone deacetylase inhibitor suberoylanilide hydroxamic acid via the activation of cathepsin B in human breast cancer cells

Dectin-1 signaling inhibits osteoclastogenesis via IL-33-induced inhibition of NFATc1

20(S)-Rg3 blocked epithelial-mesenchymal transition through DNMT3A/miR-145/FSCN1 in ovarian cancer

APIO-EE-9 is a novel Aurora A and B antagonist that suppresses esophageal cancer growth in a PDX mouse model

Brain metastases in patients with non-small cell lung cancer: the role of mutated-EGFRs with an exon 19 deletion or L858R point mutation in cancer cell dissemination

Radial artery intima-media thickness regresses after secondary prevention interventions in patients’ post-acute coronary syndrome and is associated with cardiac and kidney biomarkers

An epigenetic signature of adhesion molecules predicts poor prognosis of ovarian cancer patients

Hypertriglyceridemia in female rats during pregnancy induces obesity in male offspring via altering hypothalamic leptin signaling

Differential gene and lncRNA expression in the lower thoracic spinal cord following ischemia/reperfusion-induced acute kidney injury in rats

Development of hepatocellular cancer induced by long term low fat-high carbohydrate diet in a NAFLD/NASH mouse model

TLR4 interaction with LPS in glioma CD133+ cancer stem cells induces cell proliferation, resistance to chemotherapy and evasion from cytotoxic T lymphocyte-induced cytolysis

Structural basis of mutant-selectivity and drug-resistance related to CO-1686

SHP2 negatively regulates HLA-ABC and PD-L1 expression via STAT1 phosphorylation in prostate cancer cells

Compliance with the enhanced recovery after surgery protocol and prognosis after colorectal cancer surgery: A prospective cohort study

Value of quantitative magnetic resonance imaging T1-relaxometry in predicting contrast-enhancement in glioblastoma patients

A vitamin D receptor agonist converts CD4+ T cells to Foxp3+ regulatory T cells in patients with ulcerative colitis

The novel sphingosine-1-phosphate receptors antagonist AD2900 affects lymphocyte activation and inhibits T-cell entry into the lymph nodes

lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling

Selective ATP hydrolysis inhibition in F1Fo ATP synthase enhances radiosensitivity in non-small-cell lung cancer cells (A549)

XPG gene rs751402 C>T polymorphism and cancer risk: Evidence from 22 publications

The impact of primary tumor location on efficacy of cetuximab in metastatic colorectal cancer patients with different Kras status: a systematic review and meta-analysis

Decitabine-based chemotherapy followed by haploidentical lymphocyte infusion improves the effectiveness in elderly patients with acute myeloid leukemia

Tumor heterogeneity assessed by texture analysis on contrast-enhanced CT in lung adenocarcinoma: association with pathologic grade

Efficacy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) in targeted therapy of lung squamous cell carcinoma patients with EGFR mutation: a pooled analysis

Effect of age on long-term outcomes after stroke with atrial fibrillation: a hospital-based follow-up study in China

Dynamic changes in serum cytokine levels and their clinical significance in predicting acute GVHD

Methotrexate plus idarubicin improves outcome of patients with primary central nervous system lymphoma

Gender differences in fibrosis remodeling in patients with long-standing persistent atrial fibrillation

Safety and efficacy of p62 DNA vaccine ELENAGEN in a first-in-human trial in patients with advanced solid tumors

To predict the radiosensitivity of nasopharyngeal carcinoma using intravoxel incoherent motion MRI at 3.0 T

Advances in single-cell RNA sequencing and its applications in cancer research

Transforming growth factor β: A potential biomarker and therapeutic target of ventricular remodeling

The involvement of DARPP-32 in the pathophysiology of schizophrenia

Epigenetic dynamics and interplay during spermatogenesis and embryogenesis: implications for male fertility and offspring health

Succinate: An initiator in tumorigenesis and progression

Microbiota-gut-brain axis and the central nervous system

The role of Notch signaling in gastric carcinoma: molecular pathogenesis and novel therapeutic targets

Strategies targeting angiogenesis in advanced non-small cell lung cancer

Correction: IKKα regulates the stratification and differentiation of the epidermis: implications for skin cancer development