New perspectives for colorectal cancer

Mutational cascades in cancer

ASICs may affect GABAergic synapses

Association between tumor architecture derived from generalized Q-space MRI and survival in glioblastoma

Selective inhibition of matrix metalloproteinase-2 in the multiple myeloma-bone microenvironment

Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition

Oncogenic STAT5 signaling promotes oxidative stress in chronic myeloid leukemia cells by repressing antioxidant defenses

Epigenome-wide association study in hepatocellular carcinoma: Identification of stochastic epigenetic mutations through an innovative statistical approach

Tristetraprolin inhibits mitochondrial function through suppression of α-Synuclein expression in cancer cells

MiR-106b inhibitors sensitize TRAIL-induced apoptosis in hepatocellular carcinoma through increase of death receptor 4

Non-invasive assessment of murine PD-L1 levels in syngeneic tumor models by nuclear imaging with nanobody tracers

Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/Akt signaling in glioma

A short synthetic peptide fragment of human C2ORF40 has therapeutic potential in breast cancer

Friend leukemia virus integration 1 promotes tumorigenesis of small cell lung cancer cells by activating the miR-17-92 pathway

Pterostilbene inhibits inflammation and ROS production in chondrocytes by activating Nrf2 pathway

6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ

Decreased expression of the NKG2D ligand ULBP4 may be an indicator of poor prognosis in patients with nasopharyngeal carcinoma

Compared planning dosimetry of TOMO, VMAT and IMRT in rectal cancer with different simulated positions

Modeling the differential phenotypes of spinal muscular atrophy with high-yield generation of motor neurons from human induced pluripotent stem cells

Tumor suppressor miR-1 inhibits tumor growth and metastasis by simultaneously targeting multiple genes

LncRNAs as an intermediate in HPV16 promoting myeloid-derived suppressor cell recruitment of head and neck squamous cell carcinoma

Sulfatinib, a novel kinase inhibitor, in patients with advanced solid tumors: results from a phase I study

Long non-coding RNA-CRNDE: a novel regulator of tumor growth and angiogenesis in hepatoblastoma

Local delivery of HMGB1 in gelatin sponge scaffolds combined with mesenchymal stem cell sheets to accelerate fracture healing

ERCC6L, a DNA helicase, is involved in cell proliferation and associated with survival and progress in breast and kidney cancers

Comparative analysis of microRNA expression profiles between A549, A549/DDP and their respective exosomes

Actinidia chinensis Planch root extract inhibits cholesterol metabolism in hepatocellular carcinoma through upregulation of PCSK9

Plasma cytokine and angiogenic factors associated with prognosis and therapeutic response to sunitinib vs everolimus in advanced non-clear cell renal cell carcinoma

Overexpression of karyopherin-α2 in cholangiocarcinoma correlates with poor prognosis and gemcitabine sensitivity via nuclear translocation of DNA repair proteins

Circulating microRNA-422a is associated with lymphatic metastasis in lung cancer

Prognostic value of follistatin-like 3 in human invasive breast cancer

Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience

Comprehensive analysis of PD-L1 expression in glioblastoma multiforme

GSPE reduces lead-induced oxidative stress by activating the Nrf2 pathway and suppressing miR153 and GSK-3β in rat kidney

Lectin from Sambucus sieboldiana abrogates the anoikis resistance of colon cancer cells conferred by N-acetylglucosaminyltransferase V during hematogenous metastasis

Overwhelming rapid metabolic and structural response to apatinib in radioiodine refractory differentiated thyroid cancer

Malignant ascites-derived exosomes promote proliferation and induce carcinoma-associated fibroblasts transition in peritoneal mesothelial cells

Beluga whale pVHL enhances HIF-2α activity via inducing HIF-2α proteasomal degradation under hypoxia

Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases

Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma

Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats

Circulating uric acid levels and subsequent development of cancer in 493,281 individuals: findings from the AMORIS Study

Preclinical development of G1T38: A novel, potent and selective inhibitor of cyclin dependent kinases 4/6 for use as an oral antineoplastic in patients with CDK4/6 sensitive tumors

Drug-carrying microbubbles as a theranostic tool in convection-enhanced delivery for brain tumor therapy

Treatment for retropharyngeal metastatic undifferentiated squamous cell carcinoma from an unknown primary site: results of a prospective study with irradiation to nasopharyngeal mucosa plus bilateral neck

IK channel activation increases tumor growth and induces differential behavioral responses in two breast epithelial cell lines

High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia

Type Iγ phosphatidylinositol phosphate kinase regulates PD-L1 expression by activating NF-κB

MET exon 14 mutations as targets in routine molecular analysis of primary sarcomatoid carcinoma of the lung

Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer

Clinicopathologic study of invasive micropapillary carcinoma of the breast

Synergistic anti-tumor effect of bullfrog sialic acid-binding lectin and pemetrexed in malignant mesothelioma

Tissue recommendations for precision cancer therapy using next generation sequencing: a comprehensive single cancer center’s experiences

Local recurrences at the anastomotic area are clonally related to the primary tumor in sporadic colorectal carcinoma

Combination therapy with micellarized cyclopamine and temozolomide attenuate glioblastoma growth through Gli1 down-regulation

Eg5 inhibitor YL001 induces mitotic arrest and inhibits tumor proliferation

Identification of the miRNA-mRNA regulatory network of small cell osteosarcoma based on RNA-seq

RNA sequencing analyses reveal novel differentially expressed genes and pathways in pancreatic cancer

Association of body mass index with ER, PR and 14-3-3σ expression in tumor and stroma of type I and type II endometrial carcinoma

Analysis of STAT3 post-translational modifications (PTMs) in human prostate cancer with different Gleason Score

CK2 and PI₃K are direct molecular targets of quercetin in chronic lymphocytic leukaemia

GALNT6 expression enhances aggressive phenotypes of ovarian cancer cells by regulating EGFR activity

Anti-cancer activity of Annexin V in murine melanoma model by suppressing tumor angiogenesis

NGS based identification of mutational hotspots for targeted therapy in anaplastic thyroid carcinoma

EGFR-induced phosphorylation of type Iγ phosphatidylinositol phosphate kinase promotes pancreatic cancer progression

Differential expression of miR-195-5p in collapse of steroid-induced osteonecrosis of the femoral head

Naoling decoction restores cognitive function by inhibiting the neuroinflammatory network in a rat model of Alzheimer’s disease

Synthetic lethality of glutaminolysis inhibition, autophagy inactivation and asparagine depletion in colon cancer

Oocyte exposure to ZnO nanoparticles inhibits early embryonic development through the γ-H2AX and NF-κB signaling pathways

Characteristics of delayed intracerebral hemorrhage after ventriculoperitoneal shunt insertion

The generation and functional characterization of induced pluripotent stem cells from human intervertebral disc nucleus pulposus cells

Characterization of mouse serum exosomal small RNA content: The origins and their roles in modulating inflammatory response

The palmitoylation of the N-terminal extracellular Cys37 mediates the nuclear translocation of VPAC1 contributing to its anti-apoptotic activity

Combating acquired resistance to trastuzumab by an anti-ErbB2 fully human antibody

A transcriptional complex composed of ER(α), GATA3, FOXA1 and ELL3 regulates IL-20 expression in breast cancer cells

Large-scale clinical validation of biomarkers for pancreatic cancer using a mass spectrometry-based proteomics approach

Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery

Assessment of citalopram and escitalopram on neuroblastoma cell lines: Cell toxicity and gene modulation

Mechanism of oxidative stress p38MAPK-SGK1 signaling axis in experimental autoimmune encephalomyelitis (EAE)

Paraoxonase-1 (PON1) induces metastatic potential and apoptosis escape via its antioxidative function in lung cancer cells

A systematic approach for peptide characterization of B-cell receptor in chronic lymphocytic leukemia cells

A subset of microRNAs defining the side population of a human malignant mesothelioma cell line

Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells

Trends in the management and outcomes of patients admitted with acute coronary syndrome complicated by cardiogenic shock over the past decade: Real world data from the acute coronary syndrome Israeli survey (ACSIS)

HIF-2α dictates the susceptibility of pancreatic cancer cells to TRAIL by regulating survivin expression

Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-β1 expression

Post-operative radiotherapy is beneficial for T1/T2 triple negative breast cancer patients with four or more positive lymph nodes

Self-assembling nanoparticles encapsulating zoledronic acid inhibit mesenchymal stromal cells differentiation, migration and secretion of proangiogenic factors and their interactions with prostate cancer cells

E6AP promotes prostate cancer by reducing p27 expression

Apelin: A putative novel predictive biomarker for bevacizumab response in colorectal cancer

Differentiation of pancreatic neuroendocrine carcinoma from pancreatic ductal adenocarcinoma using magnetic resonance imaging: The value of contrast-enhanced and diffusion weighted imaging

Stratification according to recursive partitioning analysis predicts outcome in newly diagnosed glioblastomas

Gene co-expression network reveals shared modules predictive of stage and grade in serous ovarian cancers

IL13RA2 targeted alpha particle therapy against glioblastomas

Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells

Follistatin-like protein 1 promotes inflammatory reactions in nucleus pulposus cells by interacting with the MAPK and NFκB signaling pathways

Gene expression signature of Gleason score is associated with prostate cancer outcomes in a radical prostatectomy cohort

6-mercaptopurine promotes energetic failure in proliferating T cells

Establishment of mouse neuron and microglial cell co-cultured models and its action mechanism

Identification of polymorphisms in 12q24.1, ACAD10, and BRAP as novel genetic determinants of blood pressure in Japanese by exome-wide association studies

Polymorphisms in BMP2/BMP4, with estimates of mean lung dose, predict radiation pneumonitis among patients receiving definitive radiotherapy for non-small cell lung cancer

An anti-cancer WxxxE-containing azurin polypeptide inhibits Rac1-dependent STAT3 and ERK/GSK-3β signaling in breast cancer cells

The correlation between pulmonary fibrosis and methylation of peripheral Smad3 in cases of pigeon breeder's lung in a Chinese Uygur population

Accumulation of prohibitin is a common cellular response to different stressing stimuli and protects melanoma cells from ER stress and chemotherapy-induced cell death

Three hematological indexes that may serve as prognostic indicators in patients with primary, high-grade, appendicular osteosarcoma

Epistatic SNP interaction of ERCC6 with ERCC8 and their joint protein expression contribute to gastric cancer/atrophic gastritis risk

IL-17RC is critically required to maintain baseline A20 production to repress JNK isoform-dependent tumor-specific proliferation

Prediction of cervical cancer recurrence using textural features extracted from ¹⁸F-FDG PET images acquired with different scanners

Characterization of the release and biological significance of cell-free DNA from breast cancer cell lines

Differentiation capacities of skeletal muscle satellite cells in Lantang and Landrace piglets

RIP1 is a central signaling protein in regulation of TNF-α/TRAIL mediated apoptosis and necroptosis during Newcastle disease virus infection

VEGF-C expression attributes the risk for lymphatic metastases to ovarian cancer patients

Spindle cell carcinoma: the general demographics, basic clinico-pathologic characteristics, treatment, outcome and prognostic factors

ABCG2 downregulation in glioma stem cells enhances the therapeutic efficacy of demethoxycurcumin

Discoidin domain receptor 1 modulates insulin receptor signaling and biological responses in breast cancer cells

The HOTAIR, PRNCR1 and POLR2E polymorphisms are associated with cancer risk: a meta-analysis

Prognostic role of TET2 deficiency in myelodysplastic syndromes: A meta-analysis

Association between tea consumption and risk of cognitive disorders: A dose-response meta-analysis of observational studies

Relationship between exposure to PM2.5 and lung cancer incidence and mortality: A meta-analysis

Body mass index and persistent pain after breast cancer surgery: findings from the women's healthy eating and living study and a meta-analysis

The significance of microRNA-148/152 family as a prognostic factor in multiple human malignancies: a meta-analysis

The prognostic value of GLUT1 in cancers: a systematic review and meta-analysis

The influence of neoadjuvant chemotherapy on gastric cancer patients’ postoperative infectious complications: What is the negative role played by the intestinal barrier dysfunction?

Identification of risk factors and the pattern of lower cervical lymph node metastasis in esophageal cancer: implications for radiotherapy target delineation

Esophageal luminal stenosis is an independent prognostic factor in esophageal squamous cell carcinoma

Shear wave elastography combined with the thyroid imaging reporting and data system for malignancy risk stratification in thyroid nodules

Use of social network analysis and global sensitivity and uncertainty analyses to better understand an influenza outbreak

Predictive value of peripheral regulatory T cells in non-small cell lung cancer patients undergoing radiotherapy

Outcomes of metastatic spinal cord compression secondary to primary hepatocellular carcinoma with multidisciplinary treatments

The challenge in treating locally recurrent T3-4 nasopharyngeal carcinoma: the survival benefit and severe late toxicities of re-irradiation with intensity-modulated radiotherapy

In-vivo relation between plasma concentration of sorafenib and its safety in Chinese patients with metastatic renal cell carcinoma: a single-center clinical study

Peritoneal carcinomatosis: limits of diagnosis and the case for liquid biopsy

Contrast agents in dynamic contrast-enhanced magnetic resonance imaging

The associations between the MAPT polymorphisms and Alzheimer’s disease risk: a meta-analysis

Elevated heparanase expression is associated with poor prognosis in breast cancer: a study based on systematic review and TCGA data

Revisit ¹⁸F-fluorodeoxyglucose oncology positron emission tomography: “systems molecular imaging” of glucose metabolism

Lysophosphatidic acid (LPA) as a pro-fibrotic and pro-oncogenic factor: a pivotal target to improve the radiotherapy therapeutic index

Breaking the crosstalk of the cellular tumorigenic network: Hypothesis for addressing resistances to targeted therapies in advanced NSCLC

Non-coding RNAs: new biomarkers and therapeutic targets for esophageal cancer

Personalizing Chinese medicine by integrating molecular features of diseases and herb ingredient information: application to acute myeloid leukemia

Correction: H₂O₂ treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway