Glial phenotype modulators

Targeting glutamate transporter-1 in neurological diseases

The stem cell/cancer stem cell marker ALDH1A3 regulates the expression of the survival factor tissue transglutaminase, in mesenchymal glioma stem cells

Pregnancy at early age is associated with a reduction of progesterone-responsive cells and epithelial Wnt signaling in human breast tissue

The influence of marital status on the stage at diagnosis, treatment, and survival of adult patients with gastric cancer: a population-based study

CD47 deficiency in tumor stroma promotes tumor progression by enhancing angiogenesis

Synergistic induction of apoptosis by salinomycin and gefitinib through lysosomal and mitochondrial dependent pathway overcomes gefitinib resistance in colorectal cancer

Mammalian Eps15 homology domain 1 promotes metastasis in non-small cell lung cancer by inducing epithelial-mesenchymal transition

MicroRNA-382-5p aggravates breast cancer progression by regulating the RERG/Ras/ERK signaling axis

HMGCS2 enhances invasion and metastasis via direct interaction with PPARα to activate Src signaling in colorectal cancer and oral cancer

Stat5 deficiency decreases transcriptional heterogeneity and supports emergence of hematopoietic sub-populations

Prognostic significance of serum chemerin levels in patients with non-small cell lung cancer

Overlooked FANCD2 variant encodes a promising, portent tumor suppressor, and alternative polyadenylation contributes to its expression

Subdiaphragmatic vagotomy promotes tumor growth and reduces survival via TNFα in a murine pancreatic cancer model

AMP-activated protein kinase reduces inflammatory responses and cellular senescence in pulmonary emphysema

Combination antiretroviral therapy (cART) restores HIV-1 infection-mediated impairment of JAK-STAT signaling pathway

Osteotropism of neuroendocrine tumors: role of the CXCL12/CXCR4 pathway in promoting EMT in vitro

Diet-induced obesity links to ER positive breast cancer progression via LPA/PKD-1-CD36 signaling-mediated microvascular remodeling

Clinicopathological signature of p21-activated kinase 1 in prostate cancer and its regulation of proliferation and autophagy via the mTOR signaling pathway

¹⁸F-FDG/¹⁸F-FES standardized uptake value ratio determined using PET predicts prognosis in uterine sarcoma

AvidinOX-anchored biotinylated trastuzumab and pertuzumab induce down-modulation of ErbB2 and tumor cell death at concentrations order of magnitude lower than not-anchored antibodies

Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors

Clinically relevant circulating microRNA profiling studies in pancreatic cancer using meta-analysis

Common cytotoxic chemotherapeutics induce epithelial-mesenchymal transition (EMT) downstream of ER stress

BRCA1 p.His1673del is a pathogenic mutation associated with a predominant ovarian cancer phenotype

HMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma

Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks

MicroRNA-146a promote cell migration and invasion in human colorectal cancer via carboxypeptidase M/src-FAK pathway

Ensnaring membrane type 1-matrix metalloproteinase (MT1-MMP) with tissue inhibitor of metalloproteinase (TIMP)-2 using the haemopexin domain of the protease as a carrier: a targeted approach in cancer inhibition

A NOTCH-sensitive uPAR-regulated oncolytic adenovirus effectively suppresses pancreatic tumor growth and triggers synergistic anticancer effects with gemcitabine and nab-paclitaxel

Therapeutically blocking interleukin-11 receptor-α enhances doxorubicin cytotoxicity in high grade type I endometrioid tumours

TRIM47 overexpression is a poor prognostic factor and contributes to carcinogenesis in non-small cell lung carcinoma

Conditionally reprogrammed normal and primary tumor prostate epithelial cells: a novel patient-derived cell model for studies of human prostate cancer

Identification of TMEM208 and PQLC2 as reference genes for normalizing mRNA expression in colorectal cancer treated with aspirin

Somatic molecular subtyping of prostate tumors from HOXB13 G84E carriers

MALAT1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing miR-203 and promoting thymidylate synthase expression

Identification of sphingosine kinase 1 (SphK1) as a primary target of icaritin in hepatocellular carcinoma cells

Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma

Rottlerin as a novel chemotherapy agent for adrenocortical carcinoma

Geraniin attenuates LPS-induced acute lung injury via inhibiting NF-κB and activating Nrf2 signaling pathways

Association of 15-hydroxyprostaglandin dehydrogenate and poor prognosis of obese breast cancer patients

Prognostic role of platelet to lymphocyte ratio in hepatocellular carcinoma: a systematic review and meta-analysis

Impact of DNA repair gene polymorphisms on the risk of biochemical recurrence after radiotherapy and overall survival in prostate cancer

Calcium-regulatory proteins as modulators of chemotherapy in human neuroblastoma

Intratumoral lactate metabolism in Barrett’s esophagus and adenocarcinoma

Mutations acquired by hepatocellular carcinoma recurrence give rise to an aggressive phenotype

Genetic variation in long noncoding RNAs and the risk of nonalcoholic fatty liver disease

Impact of vascular endothelial growth factor gene-gene and gene-smoking interaction and haplotype combination on bladder cancer risk in Chinese population

Circular RNAs signature predicts the early recurrence of stage III gastric cancer after radical surgery

Diagnostic value of FIB-4 for liver fibrosis in patients with hepatitis B: a meta-analysis of diagnostic test

LncRNA-SLC6A9-5:2: a potent sensitizer in ¹³¹I-resistant papillary thyroid carcinoma with PARP-1 induction

Oncofetal gene SALL4 and prognosis in cancer: A systematic review with meta-analysis

Diagnostic performance of magnetic resonance imaging and 3D endoanal ultrasound in detection, staging and assessment post treatment, in anal cancer

The tumor suppressor capability of p53 is dependent on non-muscle myosin IIA function in head and neck cancer

Tumor suppressor role of miR-3622b-5p in ERBB2-positive cancer

Efficacy of continuous EGFR-inhibition and role of Hedgehog in EGFR acquired resistance in human lung cancer cells with activating mutation of EGFR

Claudin-3 expression increases the malignant potential of lung adenocarcinoma cells: role of epidermal growth factor receptor activation

Differential expression of folate receptor 1 in medulloblastoma and the correlation with clinicopathological characters and target therapeutic potential

TKI rotation-induced persistent deep molecular response in multi-resistant blast crisis of Ph+ CML

Resistance of leukemia cells to cytarabine chemotherapy is mediated by bone marrow stroma, involves cell-surface equilibrative nucleoside transporter-1 removal and correlates with patient outcome

Model driven optimization of antiangiogenics + cytotoxics combination: application to breast cancer mice treated with bevacizumab + paclitaxel doublet leads to reduced tumor growth and fewer metastasis

The urokinase plasminogen activation system in gastroesophageal cancer: A systematic review and meta-analysis

Stable H3 peptide was delivered by gold nanorods to inhibit LSD1 activation and induce human mesenchymal stem cells differentiation

The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma

Circulating tumor cells in early stage lung adenocarcinoma: a case series report and literature review

Regulation of p53^wt glioma cell proliferation by androgen receptor-mediated inhibition of small VCP/p97-interacting protein expression

Hypermethylation of the CHRDL1 promoter induces proliferation and metastasis by activating Akt and Erk in gastric cancer

Identification and characterization of L1-specific endo-siRNAs essential for early embryonic development in pig

The diagnostic role of microRNA-34a in breast cancer: a systematic review and meta-analysis

CXCR1/2 pathways in paclitaxel-induced neuropathic pain

Sepia ink oligopeptide induces apoptosis and growth inhibition in human lung cancer cells

PI3K isoform inhibition associated with anti Bcr-Abl drugs shows in vitro increased anti-leukemic activity in Philadelphia chromosome-positive B-acute lymphoblastic leukemia cell lines

Predictive analysis of long non-coding RNA expression profiles in diffuse large B-cell lymphoma

Acceleration of leukocytes’ epigenetic age as an early tumor and sex-specific marker of breast and colorectal cancer

Involvement of AF1q/MLLT11 in the progression of ovarian cancer

Synergistic anti-tumor efficacy of sorafenib and fluvastatin in hepatocellular carcinoma

Over-expression of Thrombospondin 4 correlates with loss of miR-142 and contributes to migration and vascular invasion of advanced hepatocellular carcinoma

Activated Notch signaling augments cell growth in hepatocellular carcinoma via up-regulating the nuclear receptor NR4A2

Monocyte chemotactic protein-1 deficiency attenuates and high-fat diet exacerbates bone loss in mice with Lewis lung carcinoma

Solitary ground-glass opacity nodules of stage IA pulmonary adenocarcinoma: combination of 18F-FDG PET/CT and high-resolution computed tomography features to predict invasive adenocarcinoma

Comparison between transrectal and transperineal prostate biopsy for detection of prostate cancer: a meta-analysis and trial sequential analysis

The cyclin-like protein, SPY1, regulates the ERα and ERK1/2 pathways promoting tamoxifen resistance

mTOR/autophagy pathway in the hippocampus of rats suffering intermittent hypoxia preconditioning and global cerebral ischemia-reperfusion

Endothelial microparticles delivering microRNA-155 into T lymphocytes are involved in the initiation of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation

Systematic review with network meta-analysis: comparative efficacy of different enteral immunonutrition formulas in patients underwent gastrectomy

Quantitative assessment of the bidirectional relationships between diabetes and depression

Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 promotes hypoxia-induced glioma migration and invasion

DEK associates with tumor stage and outcome in HPV16 positive oropharyngeal squamous cell carcinoma

Elevated serum visfatin levels are associated with poor prognosis of hepatocellular carcinoma

Parthenolide suppresses non-small cell lung cancer GLC-82 cells growth via B-Raf/MAPK/Erk pathway

The protection of meloxicam against chronic aluminium overload-induced liver injury in rats

Hepatocyte growth factor is a prognostic marker in patients with colorectal cancer: a meta-analysis

The rs1550117 A>G variant in DNMT3A gene promoter significantly increases non-small cell lung cancer susceptibility in a Han Chinese population

UBE2L6/UBCH8 and ISG15 attenuate autophagy in esophageal cancer cells

The role of ROS and subsequent DNA-damage response in PUMA-induced apoptosis of ovarian cancer cells

C-terminal truncated hepatitis B virus X protein regulates tumorigenicity, self-renewal and drug resistance via STAT3/Nanog signaling pathway

The correlation between programmed death-ligand 1 expression and driver gene mutations in NSCLC

PI3K pathway mutations are associated with longer time to local progression after radioembolization of colorectal liver metastases

Progression of motor deficits in glioma-bearing mice: impact of CNF1 therapy at symptomatic stages

Transient activation of the PI3K/Akt pathway promotes Newcastle disease virus replication and enhances anti-apoptotic signaling responses

HRD1 sensitizes breast cancer cells to Tamoxifen by promoting S100A8 degradation

An anthocyanin rich strawberry extract induces apoptosis and ROS while decreases glycolysis and fibrosis in human uterine leiomyoma cells

Next generation mapping reveals novel large genomic rearrangements in prostate cancer

The in vitro and in vivo effects of nuclear and cytosolic parafibromin expression on the aggressive phenotypes of colorectal cancer cells: a search of potential gene therapy target

Dermis, acellular dermal matrix, and fibroblasts from different layers of pig skin exhibit different profibrotic characteristics: evidence from in vivo study

Reciprocal control of lncRNA-BCAT1 and β-catenin pathway reveals lncRNA-BCAT1 long non-coding RNA acts as a tumor suppressor in colorectal cancer

Accurate prediction of protein-protein interactions by integrating potential evolutionary information embedded in PSSM profile and discriminative vector machine classifier

Identification of long non-coding RNAs GAS5, linc0597 and lnc-DC in plasma as novel biomarkers for systemic lupus erythematosus

Shp2 confers cisplatin resistance in small cell lung cancer via an AKT-mediated increase in CA916798

Role of microRNA-21 in radiosensitivity in non-small cell lung cancer cells by targeting PDCD4 gene

Anti-cancer effect of novel PAK1 inhibitor via induction of PUMA-mediated cell death and p21-mediated cell cycle arrest

The hypoxia-activated prodrug evofosfamide in combination with multiple regimens of radiotherapy

dUTPase inhibition augments replication defects of 5-Fluorouracil

Re-expression of miR-200c suppresses proliferation, colony formation and in vivo tumor growth of murine claudin-low mammary tumor cells

Ephrin-B3 supports glioblastoma growth by inhibiting apoptosis induced by the dependence receptor EphA4

Systematic screening of isogenic cancer cells identifies DUSP6 as context-specific synthetic lethal target in melanoma

A novel lncRNA, GASL1, inhibits cell proliferation and restricts E2F1 activity

Promoter hypermethylation of LGALS4 correlates with poor prognosis in patients with urothelial carcinoma

Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway

Clinicopathologic and prognostic characteristics of alpha-fetoprotein–producing gastric cancer

Preoperative blood-routine markers and prognosis of esophageal squamous cell carcinoma: The Fujian prospective investigation of cancer (FIESTA) study

Phase 1 study of sirolimus in combination with oral cyclophosphamide and topotecan in children and young adults with relapsed and refractory solid tumors

Clinical outcome and prognostic factors of patients with early-stage epithelial ovarian cancer

Hyponatremia normalization as an independent prognostic factor in patients with advanced non-small cell lung cancer treated with first-line therapy

“Back to a false normality”: new intriguing mechanisms of resistance to PARP inhibitors

Metabolism, toxicity and anticancer activities of arsenic compounds

Prognostic value of abnormally expressed lncRNAs in ovarian carcinoma: a systematic review and meta-analysis

Aurora kinases: novel therapy targets in cancers

One-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy

Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis

Caspase-9: structure, mechanisms and clinical application

Protein calorie malnutrition, nutritional intervention and personalized cancer care

Activation of NK cells and disruption of PD-L1/PD-1 axis: two different ways for lenalidomide to block myeloma progression