GDF15 contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells

Guanylate binding protein-1 mediates EGFRvIII and promotes glioblastoma growth in vivo but not in vitro

Yap1 promotes the survival and self-renewal of breast tumor initiating cells via inhibiting Smad3 signaling

Detection rate of actionable mutations in diverse cancers using a biopsy-free (blood) circulating tumor cell DNA assay

The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma

PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response

Zoledronate blocks geranylgeranylation not farnesylation to suppress human osteosarcoma U2OS cells metastasis by EMT via Rho A activation and FAK-inhibited JNK and p38 pathways

Genetic evaluation of BRCA1-A complex genes with triple-negative breast cancer susceptibility in Chinese women

Long intergenic non-coding RNA 00152 promotes tumor cell cycle progression by binding to EZH2 and repressing p15 and p21 in gastric cancer

Helicobacter pylori CagA induces tumor suppressor gene hypermethylation by upregulating DNMT1 via AKT-NFκB pathway in gastric cancer development

Ablation of Neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression

Identification of stem-like cells and clinical significance of candidate stem cell markers in gastric cancer

RB/PLK1-dependent induced pathway by SLAMF3 expression inhibits mitosis and control hepatocarcinoma cell proliferation

Reelin promotes the adhesion and drug resistance of multiple myeloma cells via integrin β1 signaling and STAT3

The transcription factor GATA1 and the histone methyltransferase SET7 interact to promote VEGF-mediated angiogenesis and tumor growth and predict clinical outcome of breast cancer

Inhibiting receptor tyrosine kinase AXL with small molecule inhibitor BMS-777607 reduces glioblastoma growth, migration, and invasion in vitro and in vivo

JNK pathway inhibition selectively primes pancreatic cancer stem cells to TRAIL-induced apoptosis without affecting the physiology of normal tissue resident stem cells

Rh2E2, a novel metabolic suppressor, specifically inhibits energy-based metabolism of tumor cells

Human plasma metabolomics for identifying differential metabolites and predicting molecular subtypes of breast cancer

Overexpression of TRIM14 promotes tongue squamous cell carcinoma aggressiveness by activating the NF-κB signaling pathway

Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations

FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia

Identification of drugs that restore primary cilium expression in cancer cells

WISP-1 promotes VEGF-C-dependent lymphangiogenesis by inhibiting miR-300 in human oral squamous cell carcinoma cells

Identifying molecular genetic features and oncogenic pathways of clear cell renal cell carcinoma through the anatomical (PADUA) scoring system

ACTP: A webserver for predicting potential targets and relevant pathways of autophagy-modulating compounds

CD133 expression may be useful as a prognostic indicator in colorectal cancer, a tool for optimizing therapy and supportive evidence for the cancer stem cell hypothesis: a meta-analysis

Cullin 4A (CUL4A), a direct target of miR-9 and miR-137, promotes gastric cancer proliferation and invasion by regulating the Hippo signaling pathway

Pan-cancer analysis of intratumor heterogeneity as a prognostic determinant of survival

Oncogenic K-ras confers SAHA resistance by up-regulating HDAC6 and c-myc expression

eIF4B is a convergent target and critical effector of oncogenic Pim and PI3K/Akt/mTOR signaling pathways in Abl transformants

CD93 and dystroglycan cooperation in human endothelial cell adhesion and migration

The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells

SERPINB1 expression is predictive for sensitivity and outcome of cisplatin-based chemotherapy in melanoma

A function-blocking CD47 antibody suppresses stem cell and EGF signaling in triple-negative breast cancer

Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate

Blastic plasmacytoid dendritic cell neoplasm frequently shows occult central nervous system involvement at diagnosis and benefits from intrathecal therapy

Chromothripsis-like chromosomal rearrangements induced by ionizing radiation using proton microbeam irradiation system

Prognostic role of serum concentrations of high-sensitivity C-reactive protein in patients with metastatic colorectal cancer: results from the ITACa trial

Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling

A humanized antibody for imaging immune checkpoint ligand PD-L1 expression in tumors

NMU signaling promotes endometrial cancer cell progression by modulating adhesion signaling

ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3

Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways

Phenylethyl isothiocyanate reverses cisplatin resistance in biliary tract cancer cells via glutathionylation-dependent degradation of Mcl-1

Ras-activated RSK1 phosphorylates EBP50 to regulate its nuclear localization and promote cell proliferation

miR-217 and CAGE form feedback loop and regulates the response to anti-cancer drugs through EGFR and HER2

Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC

Implication of combined PD-L1/PD-1 blockade with cytokine-induced killer cells as a synergistic immunotherapy for gastrointestinal cancer

Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway

Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-AKR1C1 pathway

Estrogen receptor beta as a prognostic factor in breast cancer patients: A systematic review and meta-analysis

Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1

OLA1 contributes to epithelial-mesenchymal transition in lung cancer by modulating the GSK3β/snail/E-cadherin signaling

MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR

Perlecan/HSPG2 and matrilysin/MMP-7 as indices of tissue invasion: tissue localization and circulating perlecan fragments in a cohort of 288 radical prostatectomy patients

Sodium alginate prevents progression of non-alcoholic steatohepatitis and liver carcinogenesis in obese and diabetic mice

Role of heme oxygenase-1 in the pathogenesis and tumorigenicity of Kaposi’s sarcoma-associated herpesvirus

The sonic hedgehog signaling pathway stimulates anaplastic thyroid cancer cell motility and invasiveness by activating Akt and c-Met

Lipid tethering of breast tumor cells enables real-time imaging of free-floating cell dynamics and drug response

Diallyl disulfide suppresses epithelial-mesenchymal transition, invasion and proliferation by downregulation of LIMK1 in gastric cancer

Meta-analysis of the differentially expressed microRNA profiles in nasopharyngeal carcinoma

Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition

Quantification of Unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples

Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus

Activation of the PD-1/PD-L1 immune checkpoint confers tumor cell chemoresistance associated with increased metastasis

The status of epidermal growth factor receptor in borderline ovarian tumours

Heterogenous ribonucleoprotein A18 (hnRNP A18) promotes tumor growth by increasing protein translation of selected transcripts in cancer cells

Estrogen receptor-mediated miR-486-5p regulation of OLFM4 expression in ovarian cancer

Neonatal bisphenol A exposure induces meiotic arrest and apoptosis of spermatogenic cells

Aminomethylphosphonic acid inhibits growth and metastasis of human prostate cancer in an orthotopic xenograft mouse model

PHOX2B is a suppressor of neuroblastoma metastasis

Construction of a new anti-CD19 chimeric antigen receptor and the anti-leukemia function study of the transduced T cells

The expression of presenilin 1 enhances carcinogenesis and metastasis in gastric cancer

Histology-based prediction of lymph node metastases in early gastric cancer as decision guidance for endoscopic resection

Effect of postoperative radiotherapy for squamous cell cancer of the breast in a surveillance epidemiology and end results population-based study