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The cover for issue 52 of Oncotarget features Figure 7, 'Flow sorting of germ cells shows reduction in meiotic germ cell population in mutant testes,' from Kumar, et al. 

Table of Contents

Editorial

Early and accurate diagnosis of pancreatic cancer

https://doi.org/10.18632/oncotarget.13142

Jeremy Sharib, and Kimberly Kirkwood
85676-85677
Abstract  |  PDF  |  How to cite

Commentary: Autophagy and Cell Death

Assembly of early machinery for autophagy induction: novel insights from high resolution microscopy

https://doi.org/10.18632/oncotarget.13144

Nicholas T. Ktistakis, Simon A. Walker, and Eleftherios Karanasios
85678-85679
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Research Papers: Gerotarget (Focus on Aging)

Different nonsynonymous polymorphisms modulate the interaction of the WRN protein to its protein partners and its enzymatic activities

https://doi.org/10.18632/oncotarget.13341

Jean-Philippe Gagné, Sophie Lachapelle, Chantal Garand, Serges P. Tsofack, Yan Coulombe, Marie-Christine Caron, Guy G. Poirier, Jean-Yves Masson, and Michel Lebel
85680-85696
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Autophagy flux induced by ginsenosideRg3 attenuates human prion proteinmediated neurotoxicity and mitochondrial dysfunction

https://doi.org/10.18632/oncotarget.13730

Ji-Hong Moon, Ju-Hee Lee, You-Jin Lee, and Sang-Youel Park
85697-85708
Abstract  |  PDF  |  Full Text  |  How to cite

Germ cellspecific sustained activation of Wnt signalling perturbs spermatogenesis in aged mice possibly through noncoding RNAs

https://doi.org/10.18632/oncotarget.13920

Manish Kumar, Joshua Atkins, Murray Cairns, Ayesha Ali, and Pradeep S. Tanwar
85709-85727
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers: Pathology

Construction of differential mRNAlncRNA crosstalk networks based on ceRNA hypothesis uncover key roles of lncRNAs implicated in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.13828

Shuang Yang, Qianqian Ning, Guobin Zhang, Hong Sun, Zhen Wang, and Yixue Li
85728-85740
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Immunology

Decreased Gαq expression in T cells correlates with enhanced cytokine production and disease activity in systemic lupus erythematosus

https://doi.org/10.18632/oncotarget.13903

Yan He, Yan Huang, Lei Tu, Jiao Luo, Bing Yu, Hongyan Qian, Lihua Duan, and Guixiu Shi
85741-85749
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

Expressions of glia maturation factorβ by tumor cells and endothelia correlate with neovascularization and poor prognosis in human glioma

https://doi.org/10.18632/oncotarget.5509

Xiao-yan Kuang, Xue-feng Jiang, Cong Chen, Xiao-rui Su, Yu Shi, Jin-rong Wu, Peng Zhang, Xin-li Zhang, You-hong Cui, Yi-fang Ping, and Xiu-wu Bian
85750-85763
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Granulocytelike myeloid derived suppressor cells GMDSC are increased in multiple myeloma and are driven by dysfunctional mesenchymal stem cells MSC

https://doi.org/10.18632/oncotarget.7969

Cesarina Giallongo, Daniele Tibullo, Nunziatina L. Parrinello, Piera La Cava, Michelino Di Rosa, Vincenzo Bramanti, Cosimo Di Raimondo, Concetta Conticello, Annalisa Chiarenza, Giuseppe A. Palumbo, Roberto Avola, Alessandra Romano, and Francesco Di Raimondo
85764-85775
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Quantitative imaging to evaluate malignant potential of IPMNs

https://doi.org/10.18632/oncotarget.11769

Alexander N. Hanania, Leonidas E. Bantis, Ziding Feng, Huamin Wang, Eric P. Tamm, Matthew H. Katz, Anirban Maitra, and Eugene J. Koay
85776-85784
Abstract  |  PDF  |  Full Text  |  How to cite

Combining radiomic features with a miRNA classifier may improve prediction of malignant pathology for pancreatic intraductal papillary mucinous neoplasms

https://doi.org/10.18632/oncotarget.11768

Jennifer B. Permuth, Jung Choi, Yoganand Balarunathan, Jongphil Kim, Dung-Tsa Chen, Lu Chen, Sonia Orcutt, Matthew P. Doepker, Kenneth Gage, Geoffrey Zhang, Kujtim Latifi, Sarah Hoffe, Kun Jiang, Domenico Coppola, Barbara A. Centeno, Anthony Magliocco, Qian Li, Jose Trevino, Nipun Merchant, Robert Gillies, Mokenge Malafa, and on behalf of the Florida Pancreas Collaborative
85785-85797
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Low Ki67/high ATM protein expression in malignant tumors predicts favorable prognosis in a retrospective study of early stage hormone receptor positive breast cancer

https://doi.org/10.18632/oncotarget.12622

Xiaolan Feng, Haocheng Li, Elizabeth N . Kornaga, Michelle Dean, Susan P. Lees-Miller, Karl Riabowol, Anthony M. Magliocco, Don Morris, Peter H. Watson, Emeka K . Enwere, Gwyn Bebb, and Alexander Paterson
85798-85812
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Distance to Thrombus in acute middle cerebral artery stroke predicts basal ganglia infarction after mechanical thrombectomy

https://doi.org/10.18632/oncotarget.13280

Benjamin Friedrich, Donald Lobsien, Christian Maegerlein, Silke Wunderlich, Claus Zimmer, Johannes Kaesmacher, and Justus Kleine
85813-85818
Abstract  |  PDF  |  Full Text  |  How to cite

Unique epigenetic gene profiles define human breast cancers with poor prognosis

https://doi.org/10.18632/oncotarget.13334

Samuel Peña-Llopis, Yihong Wan, and Elisabeth D. Martinez
85819-85831
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clock gene Per2 as a controller of liver carcinogenesis

https://doi.org/10.18632/oncotarget.11037

Ali Mteyrek, Elisabeth Filipski, Catherine Guettier, Alper Okyar, and Francis Lévi
85832-85847
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pyruvate attenuates the antineoplastic effect of carnosine independently from oxidative phosphorylation

https://doi.org/10.18632/oncotarget.13039

Henry Oppermann, Lutz Schnabel, Jürgen Meixensberger, and Frank Gaunitz
85848-85860
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pglycoproteinmediated chemoresistance is reversed by carbonic anhydrase XII inhibitors

https://doi.org/10.18632/oncotarget.13040

Joanna Kopecka, Gregory M. Rankin, Iris C. Salaroglio, Sally-Ann Poulsen, and Chiara Riganti
85861-85875
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Correlation between serum IL1β and miR1443p as well as their prognostic values in LUAD and LUSC patients

https://doi.org/10.18632/oncotarget.13042

Chen Wu, Bin Xu, You Zhou, Mei Ji, Dachuan Zhang, Jingting Jiang, and Changping Wu
85876-85887
Abstract  |  PDF  |  Full Text  |  How to cite

Association analysis of ANK3 gene variants with schizophrenia in a northern Chinese Han population

https://doi.org/10.18632/oncotarget.13043

Xiaojuan Guo, Yani Zhang, Jieli Du, Hua Yang, Yini Ma, Jingjie Li, Mengdan Yan, Tianbo Jin, and Xianyang Liu
85888-85894
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic variants associated with gastrointestinal symptoms in Fabry disease

https://doi.org/10.18632/oncotarget.13135

Maria Teresa Di Martino, Francesca Scionti, Simona Sestito, Angela Nicoletti, Mariamena Arbitrio, Pietro Hiram Guzzi, Valentina Talarico, Federica Altomare, Maria Teresa Sanseviero, Giuseppe Agapito, Antonio Pisani, Eleonora Riccio, Osvaldo Borrelli, Daniela Concolino, and Licia Pensabene
85895-85904
Abstract  |  PDF  |  Full Text  |  How to cite

A regulatory loop involving miR29c and Sp1 elevates the TGFβ1 mediated epithelialtomesenchymal transition in lung cancer

https://doi.org/10.18632/oncotarget.13137

Hai-wei Zhang, En-wen Wang, Li-xian Li, Shou-hui Yi, Lu-chun Li, Fa-liang Xu, Dong-lin Wang, Yong-zhong Wu, and Wei-qi Nian
85905-85916
Abstract  |  PDF  |  Full Text  |  How to cite

Glucocorticoids may compromise the effect of gefitinib in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.13185

Hsian-Yu Wang, Yu-Ling Chang, Chun-Chun Cheng, Min-Wu Chao, Su-I Lin, Shiow-Lin Pan, Chih-Cheng Hsu, Tsang-Wu Liu, Han-Chin Cheng, Ching-Ping Tseng, Shih-Jen Liu, Hui-Ju Tsai, Hsing-Yi Chang, and John T.-A. Hsu
85917-85928
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumortargeting Salmonella typhimurium A1R combined with temozolomide regresses malignant melanoma with a BRAFV600E mutation in a patientderived orthotopic xenograft PDOX model

https://doi.org/10.18632/oncotarget.13231

Kei Kawaguchi, Kentaro Igarashi, Takashi Murakami, Bartosz Chmielowski, Tasuku Kiyuna, Ming Zhao, Yong Zhang, Arun Singh, Michiaki Unno, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li, Fritz C. Eilber, and Robert M. Hoffman
85929-85936
Abstract  |  PDF  |  Full Text  |  How to cite

Therapyrelated acute myeloid leukemia following treatment of lymphoid malignancies

https://doi.org/10.18632/oncotarget.13262

Sarah Bertoli, Arthur Sterin, Suzanne Tavitian, Lucie Oberic, Loïc Ysebaert, Reda Bouabdallah, François Vergez, Audrey Sarry, Emilie Bérard, Françoise Huguet, Guy Laurent, Thomas Prébet, Norbert Vey, and Christian Récher
85937-85947
Abstract  |  PDF  |  Full Text  |  How to cite

Thyroid transcription factor FOXE1 interacts with ETS factor ELK1 to coregulate TERT

https://doi.org/10.18632/oncotarget.13288

Martyn Bullock, Grace Lim, Cheng Li, In Ho Choi, Shivansh Kochhar, Chris Liddle, Lei Zhang, and Roderick J. Clifton-Bligh
85948-85962
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Disrupted in schizophrenia 1 DISC1 inhibits glioblastoma development by regulating mitochondria dynamics

https://doi.org/10.18632/oncotarget.13290

Xingchun Gao, Yajing Mi, Na Guo, Zhifang Hu, Fengrui Hu, Dou liu, Lei Gao, Xingchun Gou, and Weilin Jin
85963-85974
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Depression induces poor prognosis associates with the downregulation brain derived neurotrophic factor of serum in advanced small cell lung cancer

https://doi.org/10.18632/oncotarget.13291

Yufeng Wu, Ruirui Si, Sen Yang, Suhua Xia, Zelai He, Lili Wang, Zhen He, Qiming Wang, and Hong Tang
85975-85986
Abstract  |  PDF  |  Full Text  |  How to cite

Overexpression of FZD7 promotes glioma cell proliferation by upregulating TAZ

https://doi.org/10.18632/oncotarget.13292

Xia Qiu, Jianguo Jiao, Yidong Li, and Tian Tian
85987-85999
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cigarette smoking reduced renal function deterioration in hypertensive patients may be mediated by elevated homocysteine

https://doi.org/10.18632/oncotarget.13308

Feifei Huang, Jie Chen, Xun Liu, Feng Han, Qingqing Cai, Guicheng Peng, Kun Zhang, Weiqing Chen, Jingfeng Wang, and Hui Huang
86000-86010
Abstract  |  PDF  |  Full Text  |  How to cite

Fibroblast growth factor signalling induces loss of progesterone receptor in breast cancer cells

https://doi.org/10.18632/oncotarget.13322

Dominika Piasecka, Kamila Kitowska, Dominika Czaplinska, Kamil Mieczkowski, Magdalena Mieszkowska, Lukasz Turczyk, Andrzej C. Skladanowski, Anna J. Zaczek, Wojciech Biernat, Radzislaw Kordek, Hanna M. Romanska, and Rafal Sadej
86011-86025
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Acidic pH reduces VEGFmediated endothelial cell responses by downregulation of VEGFR2; relevance for antiangiogenic therapies

https://doi.org/10.18632/oncotarget.13323

Seraina Faes, Emilie Uldry, Anne Planche, Tania Santoro, Catherine Pythoud, Nicolas Demartines, and Olivier Dormond
86026-86038
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interferoninduced transmembrane protein 1 IFITM1 is required for the progression of colorectal cancer

https://doi.org/10.18632/oncotarget.13325

Ita Novita Sari, Ying-Gui Yang, Lan Thi Hanh Phi, Hyungjoo Kim, Moo Jun Baek, Dongjun Jeong, and Hyog Young Kwon
86039-86050
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The chromatinremodeling enzyme BRG1 promotes colon cancer progression via positive regulation of WNT3A

https://doi.org/10.18632/oncotarget.13326

Shengtao Lin, Tao Jiang, Ling Ye, Zhongbo Han, Yuan Liu, Chenchen Liu, Chenwei Yuan, Senlin Zhao, Jian Chen, Jingtao Wang, Huamei Tang, Su Lu, Liguang Yang, Xiaoliang Wang, Dongwang Yan, Zhihai Peng, and Junwei Fan
86051-86063
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

An earlyscreening biomarker of endometrial carcinoma: NGAL is associated with epitheliomesenchymal transition

https://doi.org/10.18632/oncotarget.13340

Ting Li, Li Yu, Jia Wen, Qinping Liao, and Zhaohui Liu
86064-86074
Abstract  |  PDF  |  Full Text  |  How to cite

Adipocytes secreted leptin is a protumor factor for survival of multiple myeloma under chemotherapy

https://doi.org/10.18632/oncotarget.13342

Wen Yu, De-Dong Cao, Qiu-bai Li, Hui-ling Mei, Yu Hu, and Tao Guo
86075-86086
Abstract  |  PDF  |  Full Text  |  How to cite

A novel highly potent trivalent TGFβ receptor trap inhibits earlystage tumorigenesis and tumor cell invasion in murine Ptendeficient prostate glands

https://doi.org/10.18632/oncotarget.13343

Tai Qin, Lindsey Barron, Lu Xia, Haojie Huang, Maria M. Villarreal, John Zwaagstra, Cathy Collins, Junhua Yang, Christian Zwieb, Ravindra Kodali, Cynthia S. Hinck, Sun Kyung Kim, Robert L. Reddick, Chang Shu, Maureen D. O’Connor-McCourt, Andrew P. Hinck, and Lu-Zhe Sun
86087-86102
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR1 inhibits progression of highrisk papillomavirusassociated human cervical cancer by targeting G6PD

https://doi.org/10.18632/oncotarget.13344

Tao Hu, Ye-Fei Chang, zhangang Xiao, Rui Mao, Jun Tong, Bo Chen, Guang-Cai Liu, Ying Hong, Hong-Lan Chen, Shu-Yi Kong, Yan-Mei Huang, Yan-Bin Xiyang, and Hua Jin
86103-86116
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Newcastle disease virus employs macropinocytosis and Rab5adependent intracellular trafficking to infect DF1 cells

https://doi.org/10.18632/oncotarget.13345

Lei Tan, Yuqiang Zhang, Yuan Zhan, Yanmei Yuan, Yingjie Sun, Xusheng Qiu, Chunchun Meng, Cuiping Song, Ying Liao, and Chan Ding
86117-86133
Abstract  |  PDF  |  Full Text  |  How to cite

Gli1 promotes colorectal cancer metastasis in a Foxm1dependent manner by activating EMT and PI3KAKT signaling

https://doi.org/10.18632/oncotarget.13348

Chuan Zhang, Yong Wang, YiFei Feng, Yue Zhang, Bing Ji, Sen Wang, Ye Sun, Chunyan Zhu, Dongsheng Zhang, and Yueming Sun
86134-86147
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic and diagnostic potential of isocitrate dehydrogenase 1 in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.13351

Xuan Chen, Qingbao Li, Cong Wang, Wenzhe Xu, Lihui Han, Yuan Liu, Bowen Liu, Shanghui Guan, Bingxu Tan, Jianbo Wang, Nana Wang, Qingxu Song, Yibin Jia, Jianzhen Wang, Linli Zhao, and Yufeng Cheng
86148-86160
Abstract  |  PDF  |  Full Text  |  How to cite

Aberrant overexpression of ADAR1 promotes gastric cancer progression by activating mTOR/p70S6K signaling

https://doi.org/10.18632/oncotarget.13354

Ning Dou, Shijun Yu, Xiaojuan Ye, Dong Yang, Yandong Li, and Yong Gao
86161-86173
Abstract  |  PDF  |  Full Text  |  How to cite

Comprehensive analysis of aberrantly expressed profiles of lncRNAs and miRNAs with associated ceRNA network in muscleinvasive bladder cancer

https://doi.org/10.18632/oncotarget.13363

Hanbo Wang, Leilei Niu, Shaobo Jiang, Jing Zhai, Ping Wang, Feng Kong, and Xunbo Jin
86174-86185
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NT1721 a novel epidithiodiketopiperazine exhibits potent in vitro and in vivo efficacy against acute myeloid leukemia

https://doi.org/10.18632/oncotarget.13364

Claudia M. Kowolik, Min Lin, Jun Xie, Larry E. Overman, and David A. Horne
86186-86197
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Suppression of hepatic stellate cell activation through downregulation of gremlin1 expression by the miR23b/27b cluster

https://doi.org/10.18632/oncotarget.13365

Xian-Yi Zeng, Yan-Qiong Zhang, Xiao-Min He, Lin-Yan Wan, Hu Wang, Yi-Ran Ni, Jie Wang, Jiang-Feng Wu, and Chang-Bai Liu
86198-86210
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Induction of the mitochondriamediated apoptosis in human esophageal cancer cells by DS2 a newly synthetic diterpenoid analog is regulated by Bax and caused by generation of reactive oxygen species

https://doi.org/10.18632/oncotarget.13367

Yong-Cheng Ma, Yu Ke, Xiaolin Zi, Fei Zhao, Lin Yuan, Ying-Li Zhu, Xia-Xia Fan, Ning-Min Zhao, Qiao-Yan Li, Yu-Hua Qin, and Hong-Min Liu
86211-86224
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Nordihydroguaiaretic acid impairs prostate cancer cell migration and tumor metastasis by suppressing neuropilin 1

https://doi.org/10.18632/oncotarget.13368

Xin Li, Shengjun Fan, Xueyang Pan, Yilixiati Xiaokaiti, Jianhui Duan, Yundi Shi, Yan Pan, Lu Tie, Xin Wang, Yuhua Li, and Xuejun Li
86225-86238
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Discovery of BPR1K871 a quinazoline based multikinase inhibitor for the treatment of AML and solid tumors: Rational design synthesis in vitro and in vivo evaluation

https://doi.org/10.18632/oncotarget.13369

Yung Chang Hsu, Mohane Selvaraj Coumar, Wen-Chieh Wang, Hui-Yi Shiao, Yi-Yu Ke, Wen-Hsing Lin, Ching-Chuan Kuo, Chun-Wei Chang, Fu-Ming Kuo, Pei-Yi Chen, Sing-Yi Wang, An-Siou Li, Chun-Hwa Chen, Po-Chu Kuo, Ching-Ping Chen, Ming-Hsine Wu, Chen-Lung Huang, Kuei-Jung Yen, Yun-I Chang, John T.-A. Hsu, Chiung-Tong Chen, Teng-Kuang Yeh, Jen-Shin Song, Chuan Shih, and Hsing-Pang Hsieh
86239-86256
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A promoter polymorphism in APJ gene is significantly associated with blood pressure changes and hypertension risk in Chinese women

https://doi.org/10.18632/oncotarget.13370

Guofeng Li, Xingyuan Sun, Dalong Zhao, Lan He, Lihong Zheng, Jing Xue, Bin Wang, and Hongming Pan
86257-86265
Abstract  |  PDF  |  Full Text  |  How to cite

Assessment of differentially expressed plasma microRNAs in nonsyndromic cleft palate and nonsyndromic cleft lip with cleft palate

https://doi.org/10.18632/oncotarget.13379

Jingyun Li, Jijun Zou, Qian Li, Ling Chen, Yanli Gao, Hui Yan, Bei Zhou, and Jun Li
86266-86279
Abstract  |  PDF  |  Full Text  |  How to cite

Intratumoral heterogeneity and chemoresistance in nonseminomatous germ cell tumor of the testis

https://doi.org/10.18632/oncotarget.13380

Mehmet Asim Bilen, Kenneth R. Hess, Matthew T. Campbell, Jennifer Wang, Russell R. Broaddus, Jose A. Karam, John F. Ward, Christopher G. Wood, Seungtaek L. Choi, Priya Rao, Miao Zhang, Aung Naing, Rosale General, Diana H. Cauley, Sue-Hwa Lin, Christopher J. Logothetis, Louis L. Pisters, and Shi-Ming Tu
86280-86289
Abstract  |  PDF  |  Full Text  |  How to cite

A microRNA biomarker panel for the noninvasive detection of bladder cancer

https://doi.org/10.18632/oncotarget.13382

Virginia Urquidi, Mandy Netherton, Evan Gomes-Giacoia, Daniel J. Serie, Jeanette Eckel-Passow, Charles J. Rosser, and Steve Goodison
86290-86299
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Myb expression is critical for myeloid leukemia development induced by Setbp1 activation

https://doi.org/10.18632/oncotarget.13383

Nhu Nguyen, Bandana A. Vishwakarma, Kevin Oakley, Yufen Han, Bartlomiej Przychodzen, Jaroslaw P. Maciejewski, and Yang Du
86300-86312
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of oxidative phosphorylation suppresses the development of osimertinib resistance in a preclinical model of EGFRdriven lung adenocarcinoma

https://doi.org/10.18632/oncotarget.13388

Matthew J. Martin, Cath Eberlein, Molly Taylor, Susan Ashton, David Robinson, and Darren Cross
86313-86325
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Octreotideperiplocymarin conjugate prodrug for improving targetability and antitumor efficiency: synthesis in vitro and in vivo evaluation

https://doi.org/10.18632/oncotarget.13389

Hui-Yun Zhang, Wen-Qian Xu, Yuan-yuan Zheng, Emmanuel Omari-Siaw, Yuan Zhu, Xia Cao, Shan-Shan Tong, Jiang-nan Yu, and Xi-ming Xu
86326-86338
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Deletion of 18q is a strong and independent prognostic feature in prostate cancer

https://doi.org/10.18632/oncotarget.13404

Martina Kluth, Maximilian Graunke, Christina Möller-Koop, Claudia Hube-Magg, Sarah Minner, Uwe Michl, Markus Graefen, Hartwig Huland, Raisa Pompe, Frank Jacobsen, Andrea Hinsch, Corinna Wittmer, Patrick Lebok, Stefan Steurer, Franziska Büscheck, Till Clauditz, Waldemar Wilczak, Guido Sauter, Thorsten Schlomm, and Ronald Simon
86339-86349
Abstract  |  PDF  |  Full Text  |  How to cite

Rad9a is required for spermatogonia differentiation in mice

https://doi.org/10.18632/oncotarget.13405

Lin Huang, Zhen-Bo Wang, Shu-Tao Qi, Xue-Shan Ma, Qiu-Xia Liang, Guo Lei, Tie-Gang Meng, Li-Feng Liang, Ye-Xin Xian, Yi Hou, Xiao-Fang Sun, Yong Zhao, Wei-Hua Wang, and Qing-Yuan Sun
86350-86358
Abstract  |  PDF  |  Full Text  |  How to cite

An NK cell line haNK expressing high levels of granzyme and engineered to express the high affinity CD16 allele

https://doi.org/10.18632/oncotarget.13411

Caroline Jochems, James W. Hodge, Massimo Fantini, Rika Fujii, Y. Maurice Morillon II, John W. Greiner, Michelle R. Padget, Sarah R. Tritsch, Kwong Yok Tsang, Kerry S. Campbell, Hans Klingemann, Laurent Boissel, Shahrooz Rabizadeh, Patrick Soon-Shiong, and Jeffrey Schlom
86359-86373
Abstract  |  PDF  |  Full Text  |  How to cite

Repurposing of curcumin as an antimetastatic agent for the treatment of epithelial ovarian cancer: in vitro model using cancer stem cell enriched ovarian cancer spheroids

https://doi.org/10.18632/oncotarget.13413

Misi He, Dong Wang, Dongling Zou, Chen Wang, Bruno Lopes-Bastos, Wen G Jiang, John Chester, Qi Zhou, and Jun Cai
86374-86387
Abstract  |  PDF  |  Full Text  |  How to cite

No role of IFITM3 in brain tumor formation in vivo

https://doi.org/10.18632/oncotarget.13199

Nevenka Dudvarski Stankovic, Nicola Hoppmann, Marcin Teodorczyk, Ella L. Kim, Matthias Bros, Alf Giese, Frauke Zipp, and Mirko H.H. Schmidt
86388-86405
Abstract  |  PDF  |  Full Text  |  How to cite

Patientderived glioblastoma stem cells respond differentially to targeted therapies

https://doi.org/10.18632/oncotarget.13415

Pratik Kanabur, Sujuan Guo, Cara M. Rodgers, Gary R. Simonds, Deborah F. Kelly, Robert G. Gourdie, Zhi Sheng, and Zhi Sheng
86406-86419
Abstract  |  PDF  |  Full Text  |  How to cite

MYC associated zinc finger protein promotes the invasion and metastasis of hepatocellular carcinoma by inducing epithelial mesenchymal transition

https://doi.org/10.18632/oncotarget.13416

Wei Luo, Xiaonian Zhu, Wei Liu, Yuan Ren, Chunhua Bei, Linyuan Qin, Xueyan Miao, Fen Tang, Guifang Tang, and Shengkui Tan
86420-86432
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Wholeexome and transcriptome sequencing of refractory diffuse large Bcell lymphoma

https://doi.org/10.18632/oncotarget.13239

Ha Young Park, Seung-Bok Lee, Hae-Yong Yoo, Suk-Jin Kim, Won-Seog Kim, Jong-Il Kim, and Young-Hyeh Ko
86433-86445
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of HAX1 by miR125a reverses cisplatin resistance in laryngeal cancer stem cells

https://doi.org/10.18632/oncotarget.13424

Jiajia Liu, Qinglai Tang, Shisheng Li, and Xinming Yang
86446-86456
Abstract  |  PDF  |  Full Text  |  How to cite

Discovery and replication of microRNAs for breast cancer risk using genomewide profiling

https://doi.org/10.18632/oncotarget.13241

Cenny Taslim, Daniel Y. Weng, Theodore M. Brasky, Ramona G. Dumitrescu, Kun Huang, Bhaskar VS. Kallakury, Shiva Krishnan, Adana A. Llanos, Catalin Marian, Joseph McElroy, Sallie S. Schneider, Scott L. Spear, Melissa A. Troester, Jo L. Freudenheim, Susan Geyer, and Peter G. Shields
86457-86468
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Droplet digital PCR analysis of NOTCH1 gene mutations in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.13246

Angela Minervini, Crescenzio Francesco Minervini, Luisa Anelli, Antonella Zagaria, Paola Casieri, Nicoletta Coccaro, Cosimo Cumbo, Giuseppina Tota, Luciana Impera, Paola Orsini, Claudia Brunetti, Annamaria Giordano, Giorgina Specchia, and Francesco Albano
86469-86479
Abstract  |  PDF  |  Full Text  |  How to cite

Tumors with unmethylated MLH1 and the CpG island methylator phenotype are associated with a poor prognosis in stage II colorectal cancer patients

https://doi.org/10.18632/oncotarget.13441

Tao Fu, Yanliang Liu, Kai Li, Weiwei Wan, Emmanouil P. Pappou, Christine A. Iacobuzio-Donahue, Zachary Kerner, Stephen B. Baylin, Christopher L. Wolfgang, and Nita Ahuja
86480-86489
Abstract  |  PDF  |  Full Text  |  How to cite

Systematic expression analysis of the mitochondrial complex III subunits identifies UQCRC1 as biomarker in clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.13275

Jörg Ellinger, Arabella Gromes, Mirjam Poss, Maria Brüggemann, Doris Schmidt, Nadja Ellinger, Yuri Tolkach, Dimo Dietrich, Glen Kristiansen, and Stefan C. Müller
86490-86499
Abstract  |  PDF  |  Full Text  |  How to cite

Chemotherapy plus dendritic cells cocultured with cytokineinduced killer cells versus chemotherapy alone to treat advanced nonsmallcell lung cancer: A metaanalysis

https://doi.org/10.18632/oncotarget.13394

Cuiling Zhou, Donglan Liu, Jie Li, Huanhuan Sun, Xiaobin Zheng, Shuncong Wang, Guobin Hong, Saradhi Mallampati, Hongliu Sun, Xiuling Zhou, Zhibin Cheng, Hongyu Zhang, and Haiqing Ma
86500-86510
Abstract  |  PDF  |  Full Text  |  How to cite

Altered DNA methylation in neonates born largeforgestationalage is associated with cardiometabolic risk in children

https://doi.org/10.18632/oncotarget.13442

Xian-hua Lin, Dan-dan Wu, Ling Gao, Jun-yu Zhang, Hai-tao Pan, Hui Wang, Cheng Li, Ping Zhang, Meng-xi Guo, Yan-ting Wu, Ya-jing Tan, Li Jin, Yu-qian Xiang, Ju-xue Li, Jian-zhong Sheng, and He-feng Huang
86511-86521
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Increasing the efficacy of radiotherapy by modulating the CCR2/CCR5 chemokine axes

https://doi.org/10.18632/oncotarget.13287

Kelli A. Connolly, Brian A. Belt, Nathania M. Figueroa, Aditi Murthy, Ankit Patel, Minsoo Kim, Edith M. Lord, David C. Linehan, and Scott A. Gerber
86522-86535
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Complement component 7 C7 a potential tumor suppressor is correlated with tumor progression and prognosis

https://doi.org/10.18632/oncotarget.13294

Lisha Ying, Fanrong Zhang, Xiaodan Pan, Kaiyan Chen, Nan Zhang, Jiaoyue Jin, Junzhou Wu, Jianguo Feng, Herbert Yu, Hongchuan Jin, and Dan Su
86536-86546
Abstract  |  PDF  |  Full Text  |  How to cite

Decreased DACH1 expression in glomerulopathy is associated with disease progression and severity

https://doi.org/10.18632/oncotarget.13470

Qing-Quan Liu, Ya-Qun Zhou, Hui-Quan Liu, Wen-Hui Qiu, Hui Liu, Ting-Yang Hu, Qing Xu, Yong-Man Lv, and Kong-Ming Wu
86547-86560
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

An 8gene signature for prediction of prognosis and chemoresponse in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.13357

Muhammad Shahid, Tae Gyu Choi, Minh Nam Nguyen, Abel Matondo, Yong Hwa Jo, Ji Youn Yoo, Ngoc Ngo Yen Nguyen, Hyeong Rok Yun, Jieun Kim, Salima Akter, Insug Kang, Joohun Ha, Chi Hoon Maeng, Si-Young Kim, Ju-seog Lee, Jayoung Kim, and Sung Soo Kim
86561-86572
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic nutritional index as a prognostic biomarker for survival in digestive system carcinomas

https://doi.org/10.18632/oncotarget.13472

Yang Zhao, Peng Xu, Huafeng Kang, Shuai Lin, Meng Wang, Pengtao Yang, Cong Dai, Xinghan Liu, Kang Liu, Yi Zheng, and Zhijun Dai
86573-86583
Abstract  |  PDF  |  Full Text  |  How to cite

Elevated expression of STIM1 is involved in lung tumorigenesis

https://doi.org/10.18632/oncotarget.13359

Yadong Wang, Haiyu Wang, Li Li, Jiangmin Li, Teng Pan, Ding Zhang, and Haiyan Yang
86584-86593
Abstract  |  PDF  |  Full Text  |  How to cite

Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma

https://doi.org/10.18632/oncotarget.13358

Valerie B. Sampson, Nancy S. Vetter, Wendong Zhang, Pratima U. Patil, Robert W. Mason, Erika George, Richard Gorlick, and Edward A. Kolb
86594-86607
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

M2 macrophages induce ovarian cancer cell proliferation via a heparin binding epidermal growth factor/matrix metalloproteinase 9 intercellular feedback loop

https://doi.org/10.18632/oncotarget.13474

Molly J. Carroll, Arvinder Kapur, Mildred Felder, Manish S. Patankar, and Pamela K. Kreeger
86608-86620
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Associations between XRCC2 rs3218536 and ERCC2 rs13181 polymorphisms and ovarian cancer

https://doi.org/10.18632/oncotarget.13361

Wei Zhang, and Zhifen Zhang
86621-86629
Abstract  |  PDF  |  Full Text  |  How to cite

Lactate dehydrogenase is a prognostic indicator in patients with hepatocellular carcinoma treated by sorafenib: results from the real life practice in HBV endemic area

https://doi.org/10.18632/oncotarget.13428

Mu-xing Li, Hong Zhao, Xin-yu Bi, Zhi-yu Li, Xue-song Yao, Huai Li, Zhen Huang, Yue Han, Jian-guo Zhou, Jian-jun Zhao, Ye-fan Zhang, Dong-bin Zhao, and Jian-qiang Cai
86630-86647
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mouse Sirt3 promotes autophagy in AngIIinduced myocardial hypertrophy through the deacetylation of FoxO1

https://doi.org/10.18632/oncotarget.13429

Jingyuan Li, Tongshuai Chen, Ming Xiao, Na Li, Shujian Wang, Hongyan Su, Xiaobin Guo, Hui Liu, Fangying Yan, Yi Yang, Yun Zhang, and Peili Bu
86648-86659
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dysregulated human TyrosylDNA phosphodiesterase I acts as cellular toxin

https://doi.org/10.18632/oncotarget.13528

Selma M. Cuya, Evan Q. Comeaux, Keith Wanzeck, Karina J. Yoon, and Robert C.A.M. van Waardenburg
86660-86674
Abstract  |  PDF  |  Full Text  |  How to cite

Gold nanoparticles delivered miR375 for treatment of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.13431

Hui-Ying Xue, Yong Liu, Jia-Zhi Liao, Ju-Sheng Lin, Bin Li, Wei-Gang Yuan, Robert J. Lee, Lei Li, Chuan-Rui Xu, and Xing-Xing He
86675-86686
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Plasma osteoprotegerin and breast cancer risk in BRCA1 and BRCA2 mutation carriers

https://doi.org/10.18632/oncotarget.13417

Lovisa Odén, Mohammad Akbari, Tasnim Zaman, Christian F. Singer, Ping Sun, Steven A. Narod, Leonardo Salmena, and Joanne Kotsopoulos
86687-86694
Abstract  |  PDF  |  Full Text  |  How to cite

Loss of ZG16 is regulated by miR196a and contributes to stemness and progression of colorectal cancer

https://doi.org/10.18632/oncotarget.13435

Xiaobing Chen, Peng Du, Junjun She, Liang Cao, Yingchao Li, and Hongping Xia
86695-86703
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic variants in the acylphosphatase 2 gene and the risk of breast cancer in a Han Chinese population

https://doi.org/10.18632/oncotarget.13495

Fuli Zhang, Yan Zhang, Zhiping Deng, Pengcheng Xu, Xiyang Zhang, Tianbo Jin, and Qiufang Liu
86704-86712
Abstract  |  PDF  |  Full Text  |  How to cite

An XISTrelated small RNA regulates KRAS Gquadruplex formation beyond Xinactivation

https://doi.org/10.18632/oncotarget.13433

Yuli C. Chang, Chien-Chih Chiu, Chung-Yee Yuo, Wen-Ling Chan, Ya-Sian Chang, Wen-Hsin Chang, Shou-Mei Wu, Han-Lin Chou, Ta-Chih Liu, Chi-Yu Lu, Wen-Kuang Yang, and Jan-Gowth Chang
86713-86729
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Highrisk HPV genotypes and P16INK4a expression in a cohort of head and neck squamous cell carcinoma patients in Singapore

https://doi.org/10.18632/oncotarget.13502

Louise Soo Yee Tan, Petersson Fredrik, Liang Ker, Feng Gang Yu, De Yun Wang, Boon Cher Goh, Kwok Seng Loh, and Chwee Ming Lim
86730-86739
Abstract  |  PDF  |  Full Text  |  How to cite

Lgr6+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis and their absence in ensuing skin tumors

https://doi.org/10.18632/oncotarget.13436

Gerline C. van de Glind, Heggert G. Rebel, Jacoba J. Out-Luiting, Wim Zoutman, Cornelis P. Tensen, and Frank R. de Gruijl
86740-86754
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TRIM11 a direct target of miR243p promotes cell proliferation and inhibits apoptosis in colon cancer

https://doi.org/10.18632/oncotarget.13550

Yan Yin, Jun Zhong, Si-Wei Li, Jian-Zhe Li, Min Zhou, Yin Chen, Yi Sang, and Lijuan Liu
86755-86765
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Gene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line

https://doi.org/10.18632/oncotarget.13575

Caterina Peraldo Neia, Giuliana Cavalloni, Giovanna Chiorino, Paola Ostano, Massimo Aglietta, and Francesco Leone
86766-86780
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic value of threedimensional echocardiographic right ventricular ejection fraction in patients with pulmonary arterial hypertension

https://doi.org/10.18632/oncotarget.13505

Mitsushige Murata, Toshimitsu Tsugu, Takashi Kawakami, Masaharu Kataoka, Yugo Minakata, Jin Endo, Hikaru Tsuruta, Yuji Itabashi, Yuichiro Maekawa, Mitsuru Murata, and Keiichi Fukuda
86781-86790
Abstract  |  PDF  |  Full Text  |  How to cite

The association of variants in PNPLA3 and GRP78 and the risk of developing hepatocellular carcinoma in an Italian population

https://doi.org/10.18632/oncotarget.13558

Daniele Balasus, Michael Way, Caterina Fusilli, Tommaso Mazza, Marsha Y. Morgan, Melchiorre Cervello, Lydia Giannitrapani, Maurizio Soresi, Rosalia Agliastro, Manlio Vinciguerra, and Giuseppe Montalto
86791-86802
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Niclosamide and its analogs are potent inhibitors of Wnt/βcatenin mTOR and STAT3 signaling in ovarian cancer

https://doi.org/10.18632/oncotarget.13466

Rebecca C. Arend, Angelina I. Londoño-Joshi, Abhishek Gangrade, Ashwini A. Katre, Chandrika Kurpad, Yonghe Li, Rajeev S. Samant, Pui-Kai Li, Charles N. Landen, Eddy S. Yang, Bertha Hidalgo, Ronald D. Alvarez, John Michael Straughn, Andres Forero, and Donald J. Buchsbaum
86803-86815
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Peroxiredoxin 2 is essential for maintaining cancer stem celllike phenotype through activation of Hedgehog signaling pathway in colon cancer

https://doi.org/10.18632/oncotarget.13559

Rong Wang, Jinlai Wei, Shouru Zhang, Xingye Wu, Jinbao Guo, Maoxi Liu, Kunli Du, Jun Xu, Linglong Pen, Zhenbing Lv, Wenxian You, Yongfu Xiong, and Zhongxue Fu
86816-86828
Abstract  |  PDF  |  Full Text  |  How to cite

Genetic variants in the ZNF208 gene are associated with esophageal cancer in a Chinese Han population

https://doi.org/10.18632/oncotarget.13468

Huijie Wang, Jianzhong Yu, Yanling Guo, Zhengxing Zhang, Guoqi Liu, Jingjie Li, Xiyang Zhang, Tianbo Jin, and Zhaoxia Wang
86829-86835
Abstract  |  PDF  |  Full Text  |  How to cite

IL4 a direct target of miR340/429 is involved in radiationinduced aggressive tumor behavior in human carcinoma cells

https://doi.org/10.18632/oncotarget.13561

Eun Sook Kim, Young Eun Choi, Su Jin Hwang, Young-Hoon Han, Myung-Jin Park, and In Hwa Bae
86836-86856
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epigenetic inhibition of miR663b by long noncoding RNA HOTAIR promotes pancreatic cancer cell proliferation via upregulation of insulinlike growth factor 2

https://doi.org/10.18632/oncotarget.13490

Huihua Cai, Yong An, Xuemin Chen, Donglin Sun, Tongbing Chen, Yan Peng, Feng Zhu, Yong Jiang, and Xiaozhou He
86857-86870
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The antitumor drug 2hydroxyoleic acid Minerval stimulates signaling and retrograde transport

https://doi.org/10.18632/oncotarget.13508

Maria L. Torgersen, Tove Irene Klokk, Simona Kavaliauskiene, Christian Klose, Kai Simons, Tore Skotland, and Kirsten Sandvig
86871-86888
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

VENTX induces expansion of primitive erythroid cells and contributes to the development of acute myeloid leukemia in mice

https://doi.org/10.18632/oncotarget.13563

Eva Gentner, Naidu M. Vegi, Medhanie A. Mulaw, Tamoghna Mandal, Shiva Bamezai, Rainer Claus, Alpaslan Tasdogan, Leticia Quintanilla-Martinez, Alexander Grunenberg, Konstanze Döhner, Hartmut Döhner, Lars Bullinger, Torsten Haferlach, Christian Buske, Vijay P.S. Rawat, and Michaela Feuring-Buske
86889-86901
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Efficacy and safety of icotinib in treating nonsmall cell lung cancer: a systematic evaluation and metaanalysis based on 15 studies

https://doi.org/10.18632/oncotarget.13509

Rong Biaoxue, Liu Hua, Gao Wenlong, and Yang Shuanying
86902-86913
Abstract  |  PDF  |  Full Text  |  How to cite

Investigation of longterm survival outcomes and failure patterns of patients with nasopharyngeal carcinoma receiving intensitymodulated radiotherapy: a retrospective analysis

https://doi.org/10.18632/oncotarget.13564

Wei Zhao, Hao Lei, Xiaodong Zhu, Ling Li, Song Qu, and Xia Liang
86914-86925
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA214 protects against hypoxia/reoxygenation induced cell damage and myocardial ischemia/reperfusion injury via suppression of PTEN and Bim1 expression

https://doi.org/10.18632/oncotarget.13494

Xiaohui Wang, Tuanzhu Ha, Yuanping Hu, Chen Lu, Li Liu, Xia Zhang, Race Kao, John Kalbfleisch, David Williams, and Chuanfu Li
86926-86936
Abstract  |  PDF  |  Full Text  |  How to cite

Sublethal exposure to alpha radiation 223Ra dichloride enhances various carcinomas’ sensitivity to lysis by antigenspecific cytotoxic T lymphocytes through calreticulinmediated immunogenic modulation

https://doi.org/10.18632/oncotarget.13520

Anthony S. Malamas, Sofia R. Gameiro, Karin M. Knudson, and James W. Hodge
86937-86947
Abstract  |  PDF  |  Full Text  |  How to cite

Comparative proteomics of a model MCF10AKRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface

https://doi.org/10.18632/oncotarget.13566

Xiaoying Ye, King C. Chan, Andrew M. Waters, Matthew Bess, Adam Harned, Bih-Rong Wei, Jadranka Loncarek, Brian T. Luke, Benjamin C. Orsburn, Bradley D. Hollinger, Robert M. Stephens, Rachel Bagni, Alex Martinko, James A. Wells, Dwight V. Nissley, Frank McCormick, Gordon Whiteley, and Josip Blonder
86948-86971
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of ANXA3 is an independent prognostic indicator in gastric cancer and its depletion suppresses cell proliferation and tumor growth

https://doi.org/10.18632/oncotarget.13493

Wang ke, and Li Jiansheng
86972-86984
Abstract  |  PDF  |  Full Text  |  How to cite

Hepatocyte specific expression of an oncogenic variant of βcatenin results in cholestatic liver disease

https://doi.org/10.18632/oncotarget.13521

Ursula J. Lemberger, Claudia D. Fuchs, Matthias Karer, Stefanie Haas, Tatjana Stojakovic, Christian Schöfer, Hanns-Ulrich Marschall, Fritz Wrba, Makoto M. Taketo, Gerda Egger, Michael Trauner, and Christoph H. Österreicher
86985-86998
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Proteomic profiling of NCI60 extracellular vesicles uncovers common protein cargo and cancer typespecific biomarkers

https://doi.org/10.18632/oncotarget.13569

Stephanie N. Hurwitz, Mark A. Rider, Joseph L. Bundy, Xia Liu, Rakesh K. Singh, and David G. Meckes Jr.
86999-87015
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel fully human antiNCL immunoRNase for triplenegative breast cancer therapy

https://doi.org/10.18632/oncotarget.13522

Chiara D’Avino, Dario Palmieri, Ashley Braddom, Nicola Zanesi, Cindy James, Sara Cole, Francesco Salvatore, Carlo M. Croce, and Claudia De Lorenzo
87016-87030
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The disintegrin echistatin in combination with doxorubicin targets highmetastatic human osteosarcoma overexpressing ανβ3 integrin in chick embryo and nude mouse models

https://doi.org/10.18632/oncotarget.13497

Yasunori Tome, Hiroaki Kimura, Naotoshi Sugimoto, Hiroyuki Tsuchiya, Fuminori Kanaya, Michael Bouvet, and Robert M. Hoffman
87031-87036
Abstract  |  PDF  |  Full Text  |  How to cite

CCL2/EGF positive feedback loop between cancer cells and macrophages promotes cell migration and invasion in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.13523

Lu Gao, Feng-qin Wang, Hui-min Li, Jie-gang Yang, Jian-Gang Ren, Ke-fei He, Bing Liu, Wei Zhang, and Yi-Fang Zhao
87037-87051
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Suppression of Nestin reveals a critical role for p38EGFR pathway in neural progenitor cell proliferation

https://doi.org/10.18632/oncotarget.13498

Wentao Hu, Hong Lu, Shang Wang, Wenhan Yin, Xujie Liu, Lin Dong, Richard Chiu, Li Shen, Wen-Jing Lu, and Feng Lan
87052-87063
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tracing anticancer and cancerpromoting actions of alltrans retinoic acid in breast cancer to a RARα epigenetic mechanism of mammary epithelial cell fate

https://doi.org/10.18632/oncotarget.13500

Stefano Rossetti, MingQiang Ren, Nicolo Visconti, Francesca Corlazzoli, Vincenzo Gagliostro, Giulia Somenzi, Jin Yao, Yijun Sun, and Nicoletta Sacchi
87064-87080
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Curcumin increases exosomal TCF21 thus suppressing exosomeinduced lung cancer

https://doi.org/10.18632/oncotarget.13499

Hao Wu, Jingcheng Zhou, Chao Zeng, Da Wu, Zhimin Mu, Baokun Chen, Yuancai Xie, Yiwang Ye, and Jixian Liu
87081-87090
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA595 sensitizes ovarian cancer cells to cisplatin by targeting ABCB1

https://doi.org/10.18632/oncotarget.13526

Songyu Tian, Mingyue Zhang, Xiuwei Chen, Yunduo Liu, and Ge Lou
87091-87099
Abstract  |  PDF  |  Full Text  |  How to cite

KIAA0247 suppresses the proliferation angiogenesis and promote apoptosis of human glioma through inactivation of the AKT and Stat3 signaling pathway

https://doi.org/10.18632/oncotarget.13527

Ying Tan, Ning Huang, Xiang Zhang, Jiangang Hu, Si Cheng, Li Pi, and Yuan Cheng
87100-87113
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tag SNPs of long noncoding RNA TINCR affect the genetic susceptibility to gastric cancer in a Chinese population

https://doi.org/10.18632/oncotarget.13513

Xiang Ma, Chi Huang, Dakui Luo, Younan Wang, Ran Tang, Xiangkun Huan, Yi Zhu, Zekuan Xu, Ping Liu, and Li Yang
87114-87123
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Regulation of brachyury by fibroblast growth factor receptor 1 in lung cancer

https://doi.org/10.18632/oncotarget.13547

Yunping Hu, Xin Feng, Akiva Mintz, W. Jeffrey Petty, and Wesley Hsu
87124-87135
Abstract  |  PDF  |  Full Text  |  How to cite

RhoA regulates resistance to irinotecan by regulating membrane transporter and apoptosis signaling in colorectal cancer

https://doi.org/10.18632/oncotarget.13548

Huang Ruihua, Zhang Mengyi, Zhao Chong, Qiu Meng, Ma Xin, Tang Qiulin, Bi Feng, and Liu Ming
87136-87146
Abstract  |  PDF  |  Full Text  |  How to cite

Negative feedback between TAp63 and Mir133b mediates colorectal cancer suppression

https://doi.org/10.18632/oncotarget.13515

Jing Dai, Hao Wu, Yi Zhang, Kai Gao, Gui Hu, Yihang guo, Changwei Lin, and Xiaorong Li
87147-87160
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interleukin18 deteriorates Fabry cardiomyopathy and contributes to the development of left ventricular hypertrophy in Fabry patients with GLA IVS4+919 G>A mutation

https://doi.org/10.18632/oncotarget.13552

Yueh Chien, Chian-Shiu Chien, Huai-Chih Chiang, Wei-Lin Huang, Shih-Jie Chou, Wei-Chao Chang, Yuh-Lih Chang, Hsin-Bang Leu, Kuan-Hsuan Chen, Kang-Ling Wang, Ying-Hsiu Lai, Yung-Yang Liu, Kai-Hsi Lu, Hsin-Yang Li, Yen-Jen Sung, Yuh-Jyh Jong, Yann-Jang Chen, Chung-Hsuan Chen, and Wen-Chung Yu
87161-87179
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Associations between singlenucleotide polymorphisms of human exonuclease 1 and the risk of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.13517

Shengkui Tan, Ruoyun Qin, Xiaonian Zhu, Chao Tan, Jiale Song, Linyuan Qin, Liu Liu, Xiong Huang, Anhua Li, and Xiaoqiang Qiu
87180-87193
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of differentially expressed genes in the development of osteosarcoma using RNAseq

https://doi.org/10.18632/oncotarget.13554

Yihao Yang, Ya Zhang, Xin Qu, Junfeng Xia, Dongqi Li, Xiaojuan Li, Yu Wang, Zewei He, Su Li, Yonghong Zhou, Lin Xie, and Zuozhang Yang
87194-87205
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Autophagy decreases alveolar macrophage apoptosis by attenuating endoplasmic reticulum stress and oxidative stress

https://doi.org/10.18632/oncotarget.13560

Tao Fan, Lei Chen, Zhixin Huang, Zhangfan Mao, Wei Wang, Boyou Zhang, Yao Xu, Shize Pan, Hao Hu, and Qing Geng
87206-87218
Abstract  |  PDF  |  Full Text  |  How to cite

Suppression of osteopontin inhibits chemically induced hepatic carcinogenesis by induction of apoptosis in mice

https://doi.org/10.18632/oncotarget.13529

Su-Hyung Lee, Jun-Won Park, Sang-Ho Woo, Du-Min Go, Hyo-Jung Kwon, Ja-June Jang, and Dae-Yong Kim
87219-87231
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Triple negative breast cancer development can be selectively suppressed by sustaining an elevated level of cellular cyclic AMP through simultaneously blocking its efflux and decomposition

https://doi.org/10.18632/oncotarget.13601

Wei Wang, Yue Li, Jessica Y Zhu, Dongdong Fang, Han-Fei Ding, Zheng Dong, Qing Jing, Shi-Bing Su, and Shuang Huang
87232-87245
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA34a expression levels in serum and intratumoral tissue can predict bone metastasis in patients with hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.13531

Zuo-Lin Xiang, Xiao-Mei Zhao, Li Zhang, Ping Yang, Jia Fan, Zhao-You Tang, and Zhao-Chong Zeng
87246-87256
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway in human lung cancer cells by the new synthetic flavonoid LZ205

https://doi.org/10.18632/oncotarget.13535

Yi Zhang, Xuefen Xu, Wei Li, Hanchi Miao, Shaoliang Huang, Yuxin Zhou, Yang Sun, Zhiyu Li, Qinglong Guo, and Li Zhao
87257-87270
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Repurposing the antimalarial drug dihydroartemisinin suppresses metastasis of nonsmallcell lung cancer via inhibiting NFκB/GLUT1 axis

https://doi.org/10.18632/oncotarget.13536

Jie Jiang, Guojun Geng, Xiuyi Yu, Hongming Liu, Jing Gao, Hanxiang An, Chengfu Cai, Ning Li, Dongyan Shen, Xiaoqiang Wu, Lisheng Zheng, Yanjun Mi, and Shuyu Yang
87271-87283
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of aberrantly expressed glycans in gastric cancer by integrated lectin microarray and mass spectrometric analyses

https://doi.org/10.18632/oncotarget.13539

Xiang Li, Feng Guan, Dongliang Li, Zengqi Tan, Ganglong Yang, Yanli Wu, and Zhaohui Huang
87284-87300
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of different ALK mutations in a pair of neuroblastoma cell lines established at diagnosis and relapse

https://doi.org/10.18632/oncotarget.13541

Lindi Chen, Angharad Humphreys, Lisa Turnbull, Angela Bellini, Gudrun Schleiermacher, Helen Salwen, Susan L. Cohn, Nick Bown, and Deborah A. Tweddle
87301-87311
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A combination of Nottingham prognostic index and IHC4 score predicts pathological complete response of neoadjuvant chemotherapy in estrogen receptor positive breast cancer

https://doi.org/10.18632/oncotarget.13549

Weige Tan, Wei Luo, Weijuan Jia, Gehao Liang, Xinhua Xie, Wenbo Zheng, Erwei Song, Fengxi Su, and Chang Gong
87312-87322
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Investigating cytokinesis failure as a strategy in cancer therapy

https://doi.org/10.18632/oncotarget.13556

Callum McKenzie, and Pier Paolo D'Avino
87323-87341
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

An efficient iterative CBCT reconstruction approach using gradient projection sparse reconstruction algorithm

https://doi.org/10.18632/oncotarget.13567

Heui Chang Lee, Bongyong Song, Jin Sung Kim, James J. Jung, H. Harold Li, Sasa Mutic, and Justin C. Park
87342-87350
Abstract  |  PDF  |  Full Text  |  How to cite

Activation of chronic toxoplasmosis by transportation stress in a mouse model

https://doi.org/10.18632/oncotarget.13568

Bang Shen, Yuan Yuan, Jianxi Cheng, Ming Pan, Ningbo Xia, Weichao Zhang, Yifan Wang, Yanqin Zhou, and Junlong Zhao
87351-87360
Abstract  |  PDF  |  Full Text  |  How to cite

Targeting protein kinase CK2 suppresses bladder cancer cell survival via the glucose metabolic pathway

https://doi.org/10.18632/oncotarget.13571

Xiaolei Zhang, Xiao Yang, Chengdi Yang, Peng Li, Wenbo Yuan, Xiaheng Deng, Yidong Cheng, Pengchao Li, Haiwei Yang, Jun Tao, and Qiang Lu
87361-87372
Abstract  |  PDF  |  Full Text  |  How to cite

Tolllike receptor 9 expression is associated with breast cancer sensitivity to the growth inhibitory effects of bisphosphonates in vitro and in vivo

https://doi.org/10.18632/oncotarget.13570

Jouko Sandholm, Jaakko Lehtimäki, Tamiko Ishizu, Sadanandan E. Velu, Jeremy Clark, Pirkko Härkönen, Arja Jukkola-Vuorinen, Aleksi Schrey, Kevin W. Harris, Johanna M. Tuomela, and Katri S. Selander
87373-87389
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Curcumincarrying nanoparticles prevent ischemiareperfusion injury in human renal cells

https://doi.org/10.18632/oncotarget.13626

Yong Xu, Ning Hu, Wei Jiang, Hong-Fang Yuan, and Dong-Hui Zheng
87390-87401
Abstract  |  PDF  |  Full Text  |  How to cite

New differentially expressed genes and differential DNA methylation underlying refractory epilepsy

https://doi.org/10.18632/oncotarget.13642

Xi Liu, Shu Ou, Tao Xu, Shiyong Liu, Jinxian Yuan, Hao Huang, Lu Qin, Hui Yang, Lifen Chen, Xinjie Tan, and Yangmei Chen
87402-87416
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The synthetic lethal killing of RAD54Bdeficient colorectal cancer cells by PARP1 inhibition is enhanced with SOD1 inhibition

https://doi.org/10.18632/oncotarget.13654

Erin N. McAndrew, Chloe C. Lepage, and Kirk J. McManus
87417-87430
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of Semaphorin3E enhances pancreatic cancer cell growth and associates with poor patient survival

https://doi.org/10.18632/oncotarget.13704

Lin-Kin Yong, Syeling Lai, Zhengdong Liang, Ethan Poteet, Fengju Chen, George van Buren, William Fisher, Qianxing Mo, Changyi Chen, and Qizhi Yao
87431-87448
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CLDN1 expression in cervical cancer cells is related to tumor invasion and metastasis

https://doi.org/10.18632/oncotarget.13871

Wei-na Zhang, Wei Li, Xiao-li Wang, Zheng Hu, Da Zhu, Wen-cheng Ding, Dan Liu, Ke-zhen Li, Ding Ma, and Hui Wang
87449-87461
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Midkine is a serum and urinary biomarker for the detection and prognosis of nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.13865

Xin Xia, Jian-Jun Lu, Shui-Shen Zhang, Chun-Hua Su, and Hong-He Luo
87462-87472
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of polymorphisms in the telomererelated gene ACYP2 with lung cancer risk in the Chinese Han population

https://doi.org/10.18632/oncotarget.13870

Nanzheng Chen, Xiaomei Yang, Wen Guo, Jiangtao You, Qifei Wu, Guangjian Zhang, Haijun Li, Donghong Geng, Tianbo Jin, Junke Fu, and Yong Zhang
87473-87478
Abstract  |  PDF  |  Full Text  |  How to cite

Targeted therapy of multiple liver metastases after resected solitary gastric metastasis and primary pulmonary adenocarcinoma

https://doi.org/10.18632/oncotarget.13114

Ling-yu Ding, Ke-jun Liu, Zhe-long Jiang, Hai-ying Wu, and Shi-xiu Wu
87479-87484
Abstract  |  PDF  |  Full Text  |  How to cite

Clinical Research Papers

Early response to neoadjuvant chemotherapy can help predict longterm survival in patients with cervical cancer

https://doi.org/10.18632/oncotarget.11460

Xiong Li, Kecheng Huang, Qinghua Zhang, Jian Shen, Hang Zhou, Runfeng Yang, Lin Wang, Jiong Liu, Jincheng Zhang, Haiying Sun, Yao Jia, Xiaofang Du, Haoran Wang, Song Deng, Ting Ding, Jingjing Jiang, Yunping Lu, Shuang Li, Shixuan Wang, and Ding Ma
87485-87495
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A characteristic biosignature for discrimination of gastric cancer from healthy population by high throughput GCMS analysis

https://doi.org/10.18632/oncotarget.11754

Yinan Chen, Jun Zhang, Lei Guo, Lei Liu, Jingran Wen, Lu Xu, Min Yan, Zuofeng Li, Xiaoyan Zhang, Peng Nan, Jinling Jiang, Jun Ji, Jianian Zhang, Wei Cai, Huisheng Zhuang, Yan Wang, Zhenggang Zhu, and Yingyan Yu
87496-87510
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metaanalysis of bariatric surgery versus nonsurgical treatment for type 2 diabetes mellitus

https://doi.org/10.18632/oncotarget.11961

Guo-zhong Wu, Bing Cai, Feng Yu, Zheng Fang, Xing-li Fu, Hai-sen Zhou, Wen Zhang, and Zhi-qiang Tian
87511-87522
Abstract  |  PDF  |  Full Text  |  How to cite

Radiofrequency ablation versus 125Iseed brachytherapy for painful metastases involving the bone

https://doi.org/10.18632/oncotarget.11983

Dechao Jiao, Gang Wu, Jianzhuang Ren, and Xinwei Han
87523-87531
Abstract  |  PDF  |  Full Text  |  How to cite

Poorer breast cancer survival outcomes in males than females might be attributable to tumor subtype

https://doi.org/10.18632/oncotarget.12052

Qi Wu, Juanjuan Li, Shan Zhu, Juan Wu, Xiang Li, Qian Liu, Wen Wei, and Shengrong Sun
87532-87542
Abstract  |  PDF  |  Full Text  |  How to cite

Case Reports

Benefit of Sunitinib in the treatment of pulmonary primitive neuroectodermal tumors: a case report and literature review

https://doi.org/10.18632/oncotarget.13896

Chunhui Zhang, Jingchun Zhang, Guangyu Wang, Jiajia Xu, Yanlin Li, Qing Guo, Tongsen Zheng, and Yanqiao Zhang
87543-87551
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite


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