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About The Cover
The cover for issue 41 of Oncotarget features Figure 7, 'Schematic model summarizing the expression, regulation and function of CD9 in neuroblastoma and indicating the experimental strategies applied' from Fabian, et al.
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Table of Contents
Editorial
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| Drugging the “undruggable†DNAbinding domain of STAT3 |
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https://doi.org/10.18632/oncotarget.12181
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| 66324-66325 |
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| Selfregulation of BAXinduced cell death |
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https://doi.org/10.18632/oncotarget.11948
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| 66326-66327 |
Priority Research Papers
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| Three new pancreatic cancer susceptibility signals identified on chromosomes 1q321 5p1533 and 8q2421 |
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https://doi.org/10.18632/oncotarget.11041
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| 66328-66343 |
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| MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma |
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https://doi.org/10.18632/oncotarget.11662
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| 66344-66359 |
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| Noncanonical SQSTM1/p62Nrf2 pathway activation mediates proteasome inhibitor resistance in multiple myeloma cells via redox metabolic and translational reprogramming |
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https://doi.org/10.18632/oncotarget.11960
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| 66360-66385 |
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| PML/RARa inhibits PTEN expression in hematopoietic cells by competing with PU1 transcriptional activity |
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https://doi.org/10.18632/oncotarget.11964
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| 66386-66397 |
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| Smyd2 is a Mycregulated gene critical for MLLAF9 induced leukemogenesis |
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https://doi.org/10.18632/oncotarget.12012
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| 66398-66415 |
Research Papers: Gerotarget (Focus on Aging)
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| Sexspecific autophagy modulation in osteoblastic lineage: a critical function to counteract bone loss in female |
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https://doi.org/10.18632/oncotarget.12013
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| 66416-66428 |
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| NOX4 downregulation leads to senescence of human vascular smooth muscle cells |
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https://doi.org/10.18632/oncotarget.12079
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| 66429-66443 |
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| βHydroxybutyrate suppresses inflammasome formation by ameliorating endoplasmic reticulum stress via AMPK activation |
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https://doi.org/10.18632/oncotarget.12119
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| 66444-66454 |
Research Papers: Pathology
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| CircRNA expression pattern and circRNAmiRNAmRNA network in the pathogenesis of nonalcoholic steatohepatitis |
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https://doi.org/10.18632/oncotarget.12186
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| 66455-66467 |
Research Papers: Immunology
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| Suppression of human metapneumovirus HMPV infection by the innate sensing gene CEACAM1 |
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https://doi.org/10.18632/oncotarget.11979
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| 66468-66479 |
Research Papers
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| Bisphosphonates enhance EGFRTKIs efficacy in advanced NSCLC patients with EGFR activating mutation: A retrospective study |
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https://doi.org/10.18632/oncotarget.5515
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| 66480-66490 |
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| Metabolic fluxdriven sialylation alters internalization recycling and drug sensitivity of the epidermal growth factor receptor EGFR in SW1990 pancreatic cancer cells |
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https://doi.org/10.18632/oncotarget.11582
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| 66491-66511 |
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| Rottlerin exerts its antitumor activity through inhibition of Skp2 in breast cancer cells |
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https://doi.org/10.18632/oncotarget.11614
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| 66512-66524 |
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| Double mutant P53 N340Q/L344R promotes hepatocarcinogenesis through upregulation of Pim1 mediated by PKM2 and LncRNA CUDR |
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https://doi.org/10.18632/oncotarget.9089
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| 66525-66539 |
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| Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer |
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https://doi.org/10.18632/oncotarget.11658
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| 66540-66557 |
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| Perfluorooctanoic acid induces human Ishikawa endometrial cancer cell migration and invasion through activation of ERK/mTOR signaling |
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https://doi.org/10.18632/oncotarget.11684
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| 66558-66568 |
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| Clustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies |
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https://doi.org/10.18632/oncotarget.11892
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| 66569-66585 |
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| Altered expression of CD226 and CD96 on natural killer cells in patients with pancreatic cancer |
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https://doi.org/10.18632/oncotarget.11953
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| 66586-66594 |
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| Limits and potential of targeted sequencing analysis of liquid biopsy in patients with lung and colon carcinoma |
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https://doi.org/10.18632/oncotarget.10704
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| 66595-66605 |
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| Suppressed Helicobacter pyloriassociated gastric tumorigenesis in Fat1 transgenic mice producing endogenous ω3 polyunsaturated fatty acids |
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https://doi.org/10.18632/oncotarget.11261
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| 66606-66622 |
|
| Does tumor size improve the accuracy of prognostic prediction in patients with esophageal squamous cell carcinoma after surgical resection |
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https://doi.org/10.18632/oncotarget.11286
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| 66623-66634 |
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| Distinct role of interleukin6 and tumor necrosis factor receptor1 in oval cell mediated liver regeneration and inflammationassociated hepatocarcinogenesis |
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https://doi.org/10.18632/oncotarget.11365
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| 66635-66646 |
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| Inhibition of ARC decreases the survival of HEIOC1 cells after neomycin damage in vitro |
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https://doi.org/10.18632/oncotarget.11336
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| 66647-66659 |
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| Overexpression of CHKA contributes to tumor progression and metastasis and predicts poor prognosis in colorectal carcinoma |
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https://doi.org/10.18632/oncotarget.11433
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| 66660-66678 |
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| Common housekeeping proteins are upregulated in colorectal adenocarcinoma and hepatocellular carcinoma making the total protein a better housekeeper |
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https://doi.org/10.18632/oncotarget.11439
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| 66679-66688 |
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| Cheliensisin A Chel A induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation |
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https://doi.org/10.18632/oncotarget.11440
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| 66689-66699 |
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| Effect of Helicobacter pylori infection on chronic periodontitis by the change of microecology and inflammation |
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https://doi.org/10.18632/oncotarget.11449
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| 66700-66712 |
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| LFerritin targets breast cancer stem cells and delivers therapeutic and imaging agents |
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https://doi.org/10.18632/oncotarget.10920
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| 66713-66727 |
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| Coupling of LETM1 upregulation with oxidative phosphorylation and plateletderived growth factor receptor signaling via YAP1 transactivation |
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https://doi.org/10.18632/oncotarget.11456
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| 66728-66739 |
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| ROCK inhibitor reduces Mycinduced apoptosis and mediates immortalization of human keratinocytes |
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https://doi.org/10.18632/oncotarget.11458
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| 66740-66753 |
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| Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea |
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https://doi.org/10.18632/oncotarget.11479
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| 66754-66768 |
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| New therapy with ASCJ9® to suppress the prostatitis via altering the cytokine CCL2 signals |
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https://doi.org/10.18632/oncotarget.11484
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| 66769-66775 |
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| 5ALA fluorescence of cerebral metastases and its impact for the localinbrain progression |
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https://doi.org/10.18632/oncotarget.11488
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| 66776-66789 |
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| Genetic polymorphisms and response to 5fluorouracil doxorubicin and cyclophosphamide chemotherapy in breast cancer patients |
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https://doi.org/10.18632/oncotarget.11053
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| 66790-66808 |
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| JQ1 suppresses tumor growth via PTEN/PI3K/AKT pathway in endometrial cancer |
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https://doi.org/10.18632/oncotarget.11631
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| 66809-66821 |
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| Identification of SHCBP1 as a novel downstream target gene of SS18SSX1 and its functional analysis in progression of synovial sarcoma |
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https://doi.org/10.18632/oncotarget.11651
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| 66822-66834 |
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| Tumor suppressor ARF regulates tissue microenvironment and tumor growth through modulation of macrophage polarization |
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https://doi.org/10.18632/oncotarget.11652
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| 66835-66850 |
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| eIF4E promotes tumorigenesis and modulates chemosensitivity to cisplatin in esophageal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.11694
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| 66851-66864 |
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| βescin selectively targets the glioblastomainitiating cell population and reduces cell viability |
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https://doi.org/10.18632/oncotarget.11784
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| 66865-66879 |
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| Biopsyfree circulating tumor DNA assay identifies actionable mutations in lung cancer |
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https://doi.org/10.18632/oncotarget.11801
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| 66880-66891 |
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| Modulation of glycogen synthase kinase3β following TRAIL combinatorial treatment in cancer cells |
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https://doi.org/10.18632/oncotarget.11834
|
| 66892-66905 |
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| Quantification of nucleic acid quality in postmortem tissues from a cancer research autopsy program |
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https://doi.org/10.18632/oncotarget.11836
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| 66906-66921 |
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| MicroRNA126 inhibits tumor proliferation and angiogenesis of hepatocellular carcinoma by downregulating EGFL7 expression |
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https://doi.org/10.18632/oncotarget.11877
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| 66922-66934 |
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| Zinc transporters are differentially expressed in human nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.11884
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| 66935-66943 |
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| Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1pathway |
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https://doi.org/10.18632/oncotarget.11396
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| 66944-66958 |
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| Pesticide exposure and risk of bladder cancer: A metaanalysis |
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https://doi.org/10.18632/oncotarget.11397
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| 66959-66969 |
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| Identification of breast cancer cell subtypes sensitive to ATG4B inhibition |
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https://doi.org/10.18632/oncotarget.11408
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| 66970-66988 |
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| MicroRNA21 promotes TGFβ1induced epithelialmesenchymal transition in gastric cancer through upregulating PTEN expression |
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https://doi.org/10.18632/oncotarget.11888
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| 66989-67003 |
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| Developing an anticancer copperII prodrug based on the nature of cancer cell and human serum albumin carrier IIA subdomain: mouse model of breast cancer |
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https://doi.org/10.18632/oncotarget.11465
|
| 67004-67019 |
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| Prognostic value of microRNA9 in cancers: a systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.11466
|
| 67020-67032 |
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| Efficacy of bortezomib in sarcomas with high levels of MAP17 PDZK1IP1 |
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https://doi.org/10.18632/oncotarget.11475
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| 67033-67046 |
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| Prognostic significance and the role in TNM stage of extranodal metastasis within regional lymph nodes station in gastric carcinoma |
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https://doi.org/10.18632/oncotarget.11478
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| 67047-67060 |
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| Potent in vitro and in vivo effects of polyclonal antihumanmyeloma globulins |
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https://doi.org/10.18632/oncotarget.11489
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| 67061-67070 |
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| Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer |
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https://doi.org/10.18632/oncotarget.11490
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| 67071-67086 |
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| TLR2 ligandsynthetic long peptide conjugates effectively stimulate tumordraining lymph node T cells of cervical cancer patients |
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https://doi.org/10.18632/oncotarget.11512
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| 67087-67100 |
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| Association between germline homeobox B13 HOXB13 G84E allele and prostate cancer susceptibility: a metaanalysis and trial sequential analysis |
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https://doi.org/10.18632/oncotarget.11937
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| 67101-67110 |
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| Comparative metabolic and lipidomic profiling of human breast cancer cells with different metastatic potentials |
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https://doi.org/10.18632/oncotarget.11560
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| 67111-67128 |
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| An antiErbB2 fully human antibody circumvents trastuzumab resistance |
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https://doi.org/10.18632/oncotarget.11562
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| 67129-67141 |
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| Immune inflammation indicators and implication for immune modulation strategies in advanced hepatocellular carcinoma patients receiving sorafenib |
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https://doi.org/10.18632/oncotarget.11565
|
| 67142-67149 |
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| Angiotensin II type I receptor AT1R is an independent prognosticator of esophageal squamous cell carcinoma and promotes cells proliferation via mTOR activation |
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https://doi.org/10.18632/oncotarget.11567
|
| 67150-67165 |
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| CD64directed microtubule associated protein tau kills leukemic blasts ex vivo |
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https://doi.org/10.18632/oncotarget.11568
|
| 67166-67174 |
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| Tumorspecific CD4+ T cells eradicate myeloma cells genetically deficient in MHC class II display |
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https://doi.org/10.18632/oncotarget.11946
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| 67175-67182 |
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| TP53 mutation hits energy metabolism and increases glycolysis in breast cancer |
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https://doi.org/10.18632/oncotarget.11594
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| 67183-67195 |
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| TGFβ1 promotes colorectal cancer immune escape by elevating B7H3 and B7H4 via the miR155/miR143 axis |
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https://doi.org/10.18632/oncotarget.11950
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| 67196-67211 |
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| The overexpression of MDM4: an effective and novel predictor of gastric adenocarcinoma lymph node metastasis |
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https://doi.org/10.18632/oncotarget.11971
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| 67212-67222 |
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| Methionine deprivation suppresses triplenegative breast cancer metastasis in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.11615
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| 67223-67234 |
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| Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence |
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https://doi.org/10.18632/oncotarget.11972
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| 67235-67250 |
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| Oncogenic roles of the SETDB2 histone methyltransferase in gastric cancer |
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https://doi.org/10.18632/oncotarget.11625
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| 67251-67265 |
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| MTTE: an innovative strategy for the evaluation of targeted/exome enrichment efficiency |
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https://doi.org/10.18632/oncotarget.11646
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| 67266-67276 |
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| Blockade efficacy of MEK/ERKdependent autophagy enhances PI3K/Akt inhibitor NVPBKM120's therapeutic effectiveness in lung cancer cells |
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https://doi.org/10.18632/oncotarget.11645
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| 67277-67287 |
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| A directly negative interaction of miR203 and ZEB2 modulates tumor stemness and chemotherapy resistance in nasopharyngeal carcinoma |
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https://doi.org/10.18632/oncotarget.11691
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| 67288-67301 |
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| Quantitative image variables reflect the intratumoral pathologic heterogeneity of lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.11693
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| 67302-67313 |
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| Early tumor shrinkage as a predictor of favorable outcomes in patients with advanced pancreatic cancer treated with FOLFIRINOX |
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https://doi.org/10.18632/oncotarget.12007
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| 67314-67320 |
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| miR208a3p suppresses cell apoptosis by targeting PDCD4 in gastric cancer |
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https://doi.org/10.18632/oncotarget.12006
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| 67321-67332 |
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| The prognostic value of the myeloidmediated immunosuppression marker Arginase1 in classic Hodgkin lymphoma |
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https://doi.org/10.18632/oncotarget.12024
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| 67333-67346 |
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| Mycobacterium tuberculosis PPE32 promotes cytokines production and host cell apoptosis through caspase cascade accompanying with enhanced ER stress response |
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https://doi.org/10.18632/oncotarget.12030
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| 67347-67359 |
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| HLAE expression and its clinical relevance in human renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.11744
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| 67360-67372 |
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| Adenosine A3 receptor elicits chemoresistance mediated by multiple resistanceassociated protein1 in human glioblastoma stemlike cells |
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https://doi.org/10.18632/oncotarget.12033
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| 67373-67386 |
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| Cytoskeletoncentric protein transportation by exosomes transforms tumorfavorable macrophages |
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https://doi.org/10.18632/oncotarget.11794
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| 67387-67402 |
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| Correlation between positron emission tomography and Cerenkov luminescence imaging in vivo and ex vivo using 64Culabeled antibodies in a neuroblastoma mouse model |
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https://doi.org/10.18632/oncotarget.11795
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| 67403-67411 |
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| The significance of c690G>T polymorphism rs34529039 and expression of the CEBPA gene in ovarian cancer outcome |
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https://doi.org/10.18632/oncotarget.11822
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| 67412-67424 |
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| The clinicopathological and prognostic features of Chinese and Japanese inpatients with lung cancer |
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https://doi.org/10.18632/oncotarget.11850
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| 67425-67434 |
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| Detection of multiple mutations in urinary exfoliated cells from male bladder cancer patients at diagnosis and during followup |
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https://doi.org/10.18632/oncotarget.11883
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| 67435-67448 |
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| HSPB1 deficiency sensitizes melanoma cells to hyperthermia induced cell death |
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https://doi.org/10.18632/oncotarget.11894
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| 67449-67462 |
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| Bladder neck preservation improves time to continence after radical prostatectomy: a systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.11997
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| 67463-67475 |
Clinical Research Papers
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| Reduced Connexin 43 expression is associated with tumor malignant behaviors and biochemical recurrencefree survival of prostate cancer |
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https://doi.org/10.18632/oncotarget.11231
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| 67476-67484 |
|
| The preoperative sensitivemodified Glasgow prognostic score is superior to the modified Glasgow prognostic score in predicting longterm survival for esophageal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.11268
|
| 67485-67494 |
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| Phase I/II study of azacitidine and capecitabine/oxaliplatin CAPOX in refractory CIMPhigh metastatic colorectal cancer: evaluation of circulating methylated vimentin |
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https://doi.org/10.18632/oncotarget.11317
|
| 67495-67506 |
|
| Clinical and kinomic analysis identifies peripheral blood mononuclear cells as a potential pharmacodynamic biomarker in metastatic renal cell carcinoma patients treated with sunitinib |
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https://doi.org/10.18632/oncotarget.11686
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| 67507-67520 |
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| Phase I doseescalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy |
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https://doi.org/10.18632/oncotarget.11750
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| 67521-67531 |
Reviews
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| Protein arginine methylation/demethylation and cancer |
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https://doi.org/10.18632/oncotarget.11376
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| 67532-67550 |
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| Pediatric Hodgkin lymphoma– biomarkers drugs and clinical trials for translational science and medicine |
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https://doi.org/10.18632/oncotarget.11509
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| 67551-67573 |
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| Roles of SPARC in urothelial carcinogenesis progression and metastasis |
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https://doi.org/10.18632/oncotarget.11590
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| 67574-67585 |
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| Circulating tumor cells predict survival benefit from chemotherapy in patients with lung cancer |
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https://doi.org/10.18632/oncotarget.11707
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| 67586-67596 |
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| MicroRNAs and epithelialmesenchymal transition in prostate cancer |
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https://doi.org/10.18632/oncotarget.11708
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| 67597-67611 |
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| Genegene interactions in gastrointestinal cancer susceptibility |
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https://doi.org/10.18632/oncotarget.11701
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| 67612-67625 |
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| On metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancer |
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https://doi.org/10.18632/oncotarget.11759
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| 67626-67649 |
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| Tyrosine kinase inhibitors: friends or foe in treatment of hepatic fibrosis |
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https://doi.org/10.18632/oncotarget.11767
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| 67650-67660 |
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| Incidence and risk of hypertension associated with vascular endothelial growth factor receptor tyrosine kinase inhibitors in cancer patients: a comprehensive network metaanalysis of 72 randomized controlled trials involving 30013 patients |
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https://doi.org/10.18632/oncotarget.11813
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| 67661-67673 |
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| Biological functions of macrophagederived Wnt5a and its roles in human diseases |
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https://doi.org/10.18632/oncotarget.11874
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| 67674-67684 |
Corrections
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| Correction: From the core to beyond the margin: a genomic picture of glioblastoma intratumor heterogeneity |
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https://doi.org/10.18632/oncotarget.12550
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| 67685-67685 |
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Oncotarget ® is a registered trademark of Rapamycin Press LLC
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