Targeting LIM kinases in taxane resistant tumors

Novel functions of Fanconi anemia proteins in selective autophagy and inflammation

Leukocyte telomere length and mortality risk in patients with type 2 diabetes

Six plant extracts delay yeast chronological aging through different signaling pathways

Activation of proinflammatory signaling by 4-hydroxynonenal-Src adducts in aged kidneys

Phosphorylation of kinase insert domain receptor by cyclin-dependent kinase 5 at serine 229 is associated with invasive behavior and poor prognosis in prolactin pituitary adenomas

Viscoelasticity as a measurement of clot structure in poorly controlled type 2 diabetes patients: towards a precision and personalized medicine approach

ABO blood type is associated with ovarian reserve in Chinese women with subfertility

Partial loss of interleukin 2 receptor gamma function in pigs provides mechanistic insights for the study of human immunodeficiency syndrome

Epsin2 promotes polarity establishment and meiotic division through activating Cdc42 in mouse oocyte

TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells

Interaction between the human papillomavirus 16 E7 oncoprotein and gelsolin ignites cancer cell motility and invasiveness

A pilot study using dynamic contrast enhanced-MRI as a response biomarker of the radioprotective effect of memantine in patients receiving whole brain radiotherapy

SSX2 regulates focal adhesion but does not drive the epithelial to mesenchymal transition in prostate cancer

HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status

Impact of the SCF signaling pathway on leukemia stem cell-mediated ATL initiation and progression in an HBZ transgenic mouse model

The eIF2α serine 51 phosphorylation-ATF4 arm promotes HIPPO signaling and cell death under oxidative stress

Nomograms predicting long-term overall survival and cancer-specific survival in head and neck squamous cell carcinoma patients

Superiority of lymph node ratio-based staging system for prognostic prediction in 2575 patients with gastric cancer: validation analysis in a large single center

The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients

The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth

A novel CBL-B^flox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells

Dynamic fluorescent imaging with the activatable probe, γ-glutamyl hydroxymethyl rhodamine green in the detection of peritoneal cancer metastases: Overcoming the problem of dilution when using a sprayable optical probe

Etoposide-Bevacizumab a new strategy against human melanoma cells expressing stem-like traits

Oncogene FOXK1 enhances invasion of colorectal carcinoma by inducing epithelial-mesenchymal transition

An essential pathway links FLT3-ITD, HCK and CDK6 in acute myeloid leukemia

RNF216 contributes to proliferation and migration of colorectal cancer via suppressing BECN1-dependent autophagy

Impact of autoimmune diseases on outcome of patients with early breast cancer

Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling

The non-coding landscape of head and neck squamous cell carcinoma

MiR-495 inhibits esophageal squamous cell carcinoma progression by targeting Akt1

Prognostic value and their clinical implication of 89-gene signature in glioma

Icaritin, a novel FASN inhibitor, exerts anti-melanoma activities through IGF-1R/STAT3 signaling

iPhos-PseEn: Identifying phosphorylation sites in proteins by fusing different pseudo components into an ensemble classifier

Androgen-induced miR-135a acts as a tumor suppressor through downregulating RBAK and MMP11, and mediates resistance to androgen deprivation therapy

P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer

The coexistence of MET over-expression and an EGFR T790M mutation is related to acquired resistance to EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer

16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatment

Characterization of a P-Rex1 gene signature in breast cancer cells

Loss of insulin-like growth factor II imprinting is a hallmark associated with enhanced chemo/radiotherapy resistance in cancer stem cells

Associations between CYP1A1 rs1048943 A > G and rs4646903 T > C genetic variations and colorectal cancer risk: Proof from 26 case-control studies

TMPRSS2-ERG fusion protein regulates insulin-like growth factor-1 receptor (IGF1R) gene expression in prostate cancer: involvement of transcription factor Sp1

MiR-7a is an important mediator in Fas-associated protein with death domain (FADD)-regulated expression of focal adhesion kinase (FAK)

Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer

FOXC2 and CLIP4 : a potential biomarker for synchronous metastasis of ≤7-cm clear cell renal cell carcinomas

Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport

Improved therapeutic outcomes of thermal ablation on rat orthotopic liver allograft sarcoma models by radioiodinated hypericin induced necrosis targeted radiotherapy

Different metabolic responses to PI3K inhibition in NSCLC cells harboring wild-type and G12C mutant KRAS

Long non-coding RNA-H19 antagonism protects against renal fibrosis

MicroRNA-17-5p regulated apoptosis-related protein expression and radiosensitivity in oral squamous cell carcinoma caused by betel nut chewing

Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones

Induction of HOXA9 expression in three-dimensional organotypic culture of the Claudin-low breast cancer cells

YKT6 expression, exosome release, and survival in non-small cell lung cancer

CCL2/CCR2 axis is associated with postoperative survival and recurrence of patients with non-metastatic clear-cell renal cell carcinoma

Synthetic low-density lipoprotein (sLDL) selectively delivers paclitaxel to tumor with low systemic toxicity

Motility and stem cell properties induced by the epithelial-mesenchymal transition require destabilization of lipid rafts

Tris DBA palladium is highly effective against growth and metastasis of pancreatic cancer in an orthotopic model

Immunotherapy of acute leukemia by chimeric antigen receptor-modified lymphocytes using an improved Sleeping Beauty transposon platform

Is the Hong Kong Liver Cancer staging system the best guide for hepatitis B virus-related hepatocellular carcinoma patients with multiple tumors?

Combined administration of fucoidan ameliorates tumor and chemotherapy-induced skeletal muscle atrophy in bladder cancer-bearing mice

Integrating heterogeneous drug sensitivity data from cancer pharmacogenomic studies

Establishment and antitumor effects of dasatinib and PKI-587 in BD-138T, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant EGFR amplification and PTEN deletion

Effect of JNK inhibitor SP600125 on hair cell regeneration in zebrafish (Danio rerio) larvae

Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia

Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype

Epigenetic activation of MGAT3 and corresponding bisecting GlcNAc shortens the survival of cancer patients

Establishment and characterization of a penile cancer cell line, penl1, with a deleterious TP53 mutation as a paradigm of HPV-negative penile carcinogenesis

Thyroid hormone synthesis: a potential target of a Chinese herbal formula Haizao Yuhu Decoction acting on iodine-deficient goiter

Long non-coding RNA TUG1 promotes colorectal cancer metastasis via EMT pathway

Protocadherin 17 functions as a tumor suppressor suppressing Wnt/β-catenin signaling and cell metastasis and is frequently methylated in breast cancer

Overexpression of semaphorin 3A promotes tumor progression and predicts poor prognosis in hepatocellular carcinoma after curative resection

Tamoxifen synergizes with 4-(E)-{(4-hydroxyphenylimino)-methylbenzene, 1,2-diol} and 4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol}, novel azaresveratrol analogs, in inhibiting the proliferation of breast cancer cells

Long non-coding RNA HULC as a novel serum biomarker for diagnosis and prognosis prediction of gastric cancer

Up-regulation of p16 by miR-877-3p inhibits proliferation of bladder cancer

Long non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway

E1A-engineered human umbilical cord mesenchymal stem cells as carriers and amplifiers for adenovirus suppress hepatocarcinoma in mice

ARHGAP24 inhibits cell cycle progression, induces apoptosis and suppresses invasion in renal cell carcinoma

Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the accumulation and functional activity of myeloid-derived suppressor cells (MDSCs) in pancreatic cancer

Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis

MMP16 is a marker of poor prognosis in gastric cancer promoting proliferation and invasion

A key role for transketolase-like 1 in tumor metabolic reprogramming

Molecular gene signature and prognosis of non-small cell lung cancer

The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration

YAP promotes erlotinib resistance in human non-small cell lung cancer cells

The antibiotic chloramphenicol may be an effective new agent for inhibiting the growth of multiple myeloma

MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2

ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway

Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers

Adult T-cell leukemia/lymphoma in the Caribbean cohort is a distinct clinical entity with dismal response to conventional chemotherapy

Barriers to horizontal cell transformation by extracellular vesicles containing oncogenic H-ras

Osteopontin-a splice variant is overexpressed in papillary thyroid carcinoma and modulates invasive behavior

Divergent in vitro/in vivo responses to drug treatments of highly aggressive NIH-Ras cancer cells: a PET imaging and metabolomics-mass-spectrometry study

sTLR4/MD-2 complex inhibits colorectal cancer in vitro and in vivo by targeting LPS

The dual role of asporin in breast cancer progression

Hypoxia-mediated alterations and their role in the HER-2/neuregulated CREB status and localization

Lgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors

Pre- and post-diagnosis physical activity is associated with survival benefits of colorectal cancer patients: a systematic review and meta-analysis

MicroRNA-93-5p may participate in the formation of morphine tolerance in bone cancer pain mouse model by targeting Smad5

Combined genetic and epigenetic interferences with interferon signaling expose prostate cancer cells to viral infection

The natural dietary genistein boosts bacteriophage-mediated cancer cell killing by improving phage-targeted tumor cell transduction

YAP and 14-3-3γ are involved in HS-OA-induced growth inhibition of hepatocellular carcinoma cells: A novel mechanism for hydrogen sulfide releasing oleanolic acid

A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner

Melatonin suppresses autophagy in type 2 diabetic osteoporosis

Anti-proliferative and pro-apoptotic effects of GHRH antagonists in prostate cancer

A folate receptor-targeted lipoplex delivering interleukin-15 gene for colon cancer immunotherapy

Icariside II overcomes TRAIL resistance of melanoma cells through ROS-mediated downregulation of STAT3/cFLIP signaling

Controlled release strategy of paclitaxel by conjugating to matrix metalloproteinases-2 sensitive peptide

VPS34 regulates TSC1/TSC2 heterodimer to mediate RheB and mTORC1/S6K1 activation and cellular transformation

PATZ1 induces PP4R2 to form a negative feedback loop on IKK/NF-κB signaling in lung cancer

Bioinformatics facilitating the use of microarrays to delineate potential miRNA biomarkers in aristolochic acid nephropathy

Millepachine, a potential topoisomerase II inhibitor induces apoptosis via activation of NF-κB pathway in ovarian cancer

TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype

Metastatic spread in patients with gastric cancer

Proteomics-based identification of VDAC1 as a tumor promoter in cervical carcinoma

Up-regulation of fibroblast growth factor 19 and its receptor associates with progression from fatty liver to hepatocellular carcinoma

MicroRNA-184 promotes differentiation of the retinal pigment epithelium by targeting the AKT2/mTOR signaling pathway

Preclinical activity of EGFR and MEK1/2 inhibitors in the treatment of biliary tract carcinoma

Metabotyping human endometrioid endometrial adenocarcinoma reveals an implication of endocannabinoid metabolism

Disruption of tumour-host communication by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth

Inhibition of SREBP increases gefitinib sensitivity in non-small cell lung cancer cells

Potential specific immunological indicators for stroke associated infection are partly modulated by sympathetic pathway activation

Histopathological investigation of glioblastomas resected under bevacizumab treatment

Intrapericardial bevacizumab safely and effectively treats malignant pericardial effusion in advanced cancer patients

Relationship of smoking status to genomic profile, chemotherapy response and clinical outcome in patients with advanced urothelial carcinoma

Characteristics and survival of patients with metachronous or synchronous double primary malignancies: breast and thyroid cancer

miRNA expression and function in thyroid carcinomas: a comparative and critical analysis and a model for other cancers

Practical aspects of NGS-based pathways analysis for personalized cancer science and medicine

Dietary phytochemicals and cancer chemoprevention: a review of the clinical evidence

Association between the APEX1 Asp148Glu polymorphism and prostate cancer, especially among Asians: a new evidence-based analysis

CRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseases

Targeting folate receptor alpha for cancer treatment

Targeting microenvironment in cancer therapeutics

Genetic and molecular alterations in olfactory neuroblastoma: implications for pathogenesis, prognosis and treatment

FAM83 proteins: Fostering new interactions to drive oncogenic signaling and therapeutic resistance