Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis

Deletion of 14-3-3σ sensitizes mice to DMBA/TPA-induced papillomatosis

Relationship of tobacco smoking and smoking-related DNA methylation with epigenetic age acceleration

Relationship between LRRK2 R1628P polymorphism and Parkinson’s disease in Asian populations

The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus

Cell surgery and growth factors in dry age-related macular degeneration: visual prognosis and morphological study

Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival

Sex-specific metabolic interactions between liver and adipose tissue in MCD diet-induced non-alcoholic fatty liver disease

A Phosphatidic Acid (PA) conveyor system of continuous intracellular transport from cell membrane to nucleus maintains EGF receptor homeostasis

Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells

A pan-cancer analysis of MYC-PVT1 reveals CNV-unmediated deregulation and poor prognosis in renal carcinoma

Peroxiredoxin 1 promotes invasion and migration by regulating epithelial-to-mesenchymal transition during oral carcinogenesis

Transcriptomic analysis of KSHV-infected primary oral fibroblasts: The role of interferon-induced genes in the latency of oncogenic virus

Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data

Mesenchymal stem cells in combination with erythropoietin repair hyperoxia-induced alveoli dysplasia injury in neonatal mice via inhibition of TGF-β1 signaling

SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate

Circulating tumour cells in regionally metastatic cutaneous squamous cell carcinoma: A pilot study

Reduction of estradiol in human malignant pleural mesothelioma tissues may prevent tumour growth, as implied by in in-vivo and in-vitro models

Comprehensive genomic profiling of IgM multiple myeloma identifies IRF4 as a prognostic marker

Albuminuria enhances NHE3 and NCC via stimulation of mitochondrial oxidative stress/angiotensin II axis

FH535, a β-catenin pathway inhibitor, represses pancreatic cancer xenograft growth and angiogenesis

Fas ligand and lytic granule differentially control cytotoxic dynamics of natural killer cell against cancer target

Characterization of metastatic tumor antigen 1 and its interaction with hepatitis B virus X protein in NF-κB signaling and tumor progression in a woodchuck hepatocellular carcinoma model

Comprehensive analysis of differentially expressed profiles of lncRNAs and circRNAs with associated co-expression and ceRNA networks in bladder carcinoma

Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer

Human cytomegalovirus may promote tumour progression by upregulating arginase-2

Zingerone suppresses angiogenesis via inhibition of matrix metalloproteinases during tumor development

Immunogenic cell death due to a new photodynamic therapy (PDT) with glycoconjugated chlorin (G-chlorin)

Comprehensive immunohistochemical analysis of tumor microenvironment immune status in esophageal squamous cell carcinoma

Clinicopathological and prognostic significance of cyclooxygenase-2 expression in head and neck cancer: A meta-analysis

CDH1 rs9929218 variant at 16q22.1 contributes to colorectal cancer susceptibility

A novel capsid-modified oncolytic recombinant adenovirus type 5 for tumor-targeting gene therapy by intravenous route

Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms

Bayesian network meta-analysis comparing five contemporary treatment strategies for newly diagnosed acute promyelocytic leukaemia

Plasma metabolomic analysis of human hepatocellular carcinoma: Diagnostic and therapeutic study

Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer

Associations between smoking behavior-related alleles and the risk of melanoma

Pseudogene BMI1P1 expression as a novel predictor for acute myeloid leukemia development and prognosis

Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca²⁺ release

Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma

Identification of new candidate therapeutic target genes in head and neck squamous cell carcinomas

Prognostic value of the expression of cancer stem cell-related markers CD133 and CD44 in hepatocellular carcinoma: From patients to patient-derived tumor xenograft models

MiR-4638-5p inhibits castration resistance of prostate cancer through repressing Kidins220 expression and PI3K/AKT pathway activity

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors

Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth

Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate

Characterization of the CD49f⁺/CD44⁺/CD24⁻ single-cell derived stem cell population in basal-like DCIS cells

Preparation study of indocyanine green-rituximab: A new receptor-targeted tracer for sentinel lymph node in breast cancer

Downregulation of long non-coding RNA ANRIL suppresses lymphangiogenesis and lymphatic metastasis in colorectal cancer

Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model

Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer

NO-dependent attenuation of TPA-induced immunoinflammatory skin changes in Balb/c mice by pindolol, heptaminol or ATRA, but not by verapamil

Increased cancer stem cell invasion is mediated by myosin IIB and nuclear translocation

LINC00052 regulates the expression of NTRK3 by miR-128 and miR-485-3p to strengthen HCC cells invasion and migration

MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo

Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer

CCR4 promotes metastasis via ERK/NF-κB/MMP13 pathway and acts downstream of TNF-α in colorectal cancer

Obesity does not promote tumorigenesis of localized patient-derived prostate cancer xenografts

The modulation of Dicer regulates tumor immunogenicity in melanoma

Cyclin D1 represses peroxisome proliferator-activated receptor alpha and inhibits fatty acid oxidation

LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis

BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells

Vascular endothelial growth factor polymorphisms are associated with osteosarcoma susceptibility

Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10

Carbon ion irradiation withstands cancer stem cells’ migration/invasion process in Head and Neck Squamous Cell Carcinoma (HNSCC)

An overall and dose-response meta-analysis for thyrotropin and thyroid cancer risk by histological type

MicroRNA-27a promotes renal tubulointerstitial fibrosis via suppressing PPARγ pathway in diabetic nephropathy

Epidermal growth factor receptor inhibitors trigger a type I interferon response in human skin

Effect of oral antiviral treatment on long-term outcomes of radiofrequency ablation therapy for hepatitis B virus-related hepatocellular carcinoma

Hypoxia upregulates HIG2 expression and contributes to bevacizumab resistance in glioblastoma

Analysis of tissue and circulating microRNA expression during metaplastic transformation of the esophagus

Proteomic analyses of brain tumor cell lines amidst the unfolded protein response

Antitumor efficacy of the heparan sulfate mimic roneparstat (SST0001) against sarcoma models involves multi-target inhibition of receptor tyrosine kinases

IntNetLncSim: an integrative network analysis method to infer human lncRNA functional similarity

RPL27A is a target of miR-595 and may contribute to the myelodysplastic phenotype through ribosomal dysgenesis

The essential role of GATA transcription factors in adult murine prostate

Laminin-111 peptide C16 regulates invadopodia activity of malignant cells through β1 integrin, Src and ERK 1/2

TP53 codon 72 polymorphism may predict early tumour progression in paediatric pilocytic astrocytoma

The calpain system is associated with survival of breast cancer patients with large but operable inflammatory and non-inflammatory tumours treated with neoadjuvant chemotherapy

EFEMP1 promotes ovarian cancer cell growth, invasion and metastasis via activated the AKT pathway

Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer

Genetic variants in regulatory regions of microRNAs are associated with lung cancer risk

Patterns of distant metastasis in Chinese women according to breast cancer subtypes

FOXM1 promotes reprogramming of glucose metabolism in epithelial ovarian cancer cells via activation of GLUT1 and HK2 transcription

Polo-like kinase 1 inhibition diminishes acquired resistance to epidermal growth factor receptor inhibition in non-small cell lung cancer with T790M mutations

Dual tumor suppressing and promoting function of Notch1 signaling in human prostate cancer

Dragon (RGMb) induces oxaliplatin resistance in colon cancer cells

Expression of the SIBLINGs and their MMP partners in human benign and malignant prostate neoplasms

Overexpression of AKR1C3 significantly enhances human prostate cancer cells resistance to radiation

The emergence of T790M mutation in EGFR-mutant lung adenocarcinoma patients having a history of acquired resistance to EGFR-TKI: focus on rebiopsy timing and long-term existence of T790M

Transcriptome sequencing of neurologic diseases associated genes in HHV-6A infected human astrocyte

NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells

Prolactin signaling through focal adhesion complexes is amplified by stiff extracellular matrices in breast cancer cells

Downregulation of HP1α suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression

High-grade squamous intraepithelial lesion arising adjacent to vulvar lymphangioma circumscriptum: a tertiary institutional experience

Polymorphisms of multiple genes involved in NER pathway predict prognosis of gastric cancer

The number of tumorspheres cultured from peripheral blood is a predictor for presence of metastasis in patients with breast cancer

AKT-induced PKM2 phosphorylation signals for IGF-1-stimulated cancer cell growth

Expected long-term impact of screening endoscopy on colorectal cancer incidence: a modelling study

Chamaejasmenin B, a novel candidate, inhibits breast tumor metastasis by rebalancing TGF-beta paradox

MT2-MMP induces proteolysis and leads to EMT in carcinomas

Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers

Suppression of APC/C^Cdh1 has subtype specific biological effects in acute myeloid leukemia

The activation of OR51E1 causes growth suppression of human prostate cancer cells

SFMBT2 (Scm-like with four mbt domains 2) negatively regulates cell migration and invasion in prostate cancer cells

The pancreatic niche inhibits the effectiveness of sunitinib treatment of pancreatic cancer

Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress

Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3

A p53-independent apoptotic mechanism of adenoviral mutant E1A was involved in its selective antitumor activity for human cancer

miR-153-3p, a new bio-target, is involved in the pathogenesis of acute graft-versus-host disease via inhibition of indoleamine- 2,3-dioxygenase

Blockade of the chemokine receptor, CCR5, reduces the growth of orthotopically injected colon cancer cells via limiting cancer-associated fibroblast accumulation

Aurora kinase A revives dormant laryngeal squamous cell carcinoma cells via FAK/PI3K/Akt pathway activation

PD1 blockade enhances cytotoxicity of in vitro expanded natural killer cells towards myeloma cells

Significant benefits of adding neoadjuvant chemotherapy before concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma: a meta-analysis of randomized controlled trials

Ubiquitin-specific protease 2 decreases p53-dependent apoptosis in cutaneous T-cell lymphoma

Immunotherapy based on dendritic cells pulsed with CTPFoxM1 fusion protein protects against the development of hepatocellular carcinoma

MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia

miR-200b is a key regulator of tumor progression and metabolism targeting lactate dehydrogenase A in human malignant glioma

MiRNA-200a expression is inverse correlation with hepatocyte growth factor expression in stromal fibroblasts and its high expression predicts a good prognosis in patients with non-small cell lung cancer

A classical PKA inhibitor increases the oncolytic effect of M1 virus via activation of exchange protein directly activated by cAMP 1

IGF2-derived miR-483 mediated oncofunction by suppressing DLC-1 and associated with colorectal cancer

The anti-tumor efficacy of 3-(2-Nitrophenyl) propionic acid-paclitaxel (NPPA-PTX): a novel paclitaxel bioreductive prodrug

EphrinA4 plays a critical role in α4 and αL mediated survival of human CLL cells during extravasation

Inhibition of ERα/ERK/P62 cascades induces “autophagic switch” in the estrogen receptor-positive breast cancer cells exposed to gemcitabine

Enhanced cytotoxicity of reovirus and radiotherapy in melanoma cells is mediated through increased viral replication and mitochondrial apoptotic signalling

ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma

miR-130b, an onco-miRNA in bladder cancer, is directly regulated by NF-κB and sustains NF-κB activation by decreasing Cylindromatosis expression

Integrated omics-analysis reveals Wnt-mediated NAD⁺ metabolic reprogramming in cancer stem-like cells

Simultaneous multitarget radiotherapy using helical tomotherapy and its combination with sorafenib for pulmonary metastases from hepatocellular carcinoma

Clinical value of fluorine-18 2-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in penile cancer

Epigallocatechin-3-gallate ameliorates radiation-induced acute skin damage in breast cancer patients undergoing adjuvant radiotherapy

Age-specific effects on the prognosis after surgery for gastric cancer: A SEER population-based analysis

Emerging therapeutic targets in esophageal adenocarcinoma

KIFC1: a promising chemotherapy target for cancer treatment?

Circulating adiponectin levels in various malignancies: an updated meta-analysis of 107 studies

Mantle cell lymphoma in the era of precision medicine-diagnosis, biomarkers and therapeutic agents

The insulin-like growth factor system in multiple myeloma: diagnostic and therapeutic potential

Optical imaging probes in oncology

Targeted inhibition of STATs and IRFs as a potential treatment strategy in cardiovascular disease

Physiological and pathological implications of 5-hydroxymethylcytosine in diseases

Circulating tumor DNA: a promising biomarker in the liquid biopsy of cancer