Integrated in vivo genetic and pharmacologic screening identifies co-inhibition of EGRF and ROCK as a potential treatment regimen for triple-negative breast cancer

Baicalein is an available anti-atherosclerotic compound through modulation of nitric oxide-related mechanism under oxLDL exposure

Tracing the origin of Treponema pallidum in China using next-generation sequencing

Persistent donor derived Vδ4 T cell clones may improve survival for recurrent T cell acute lymphoblastic leukemia after HSCT and DLI

IL-17 down-regulates the immunosuppressive capacity of olfactory ecto-mesenchymal stem cells in murine collagen-induced arthritis

In vitro studies implicate an imbalanced activation of dendritic cells in the pathogenesis of murine autoimmune pancreatitis

Liquid biopsy monitoring uncovers acquired RAS-mediated resistance to cetuximab in a substantial proportion of patients with head and neck squamous cell carcinoma

A key role of GARP in the immune suppressive tumor microenvironment

Tailored chemokine receptor modification improves homing of adoptive therapy T cells in a spontaneous tumor model

RIC versus MAC UCBT in adults with AML: A report from Eurocord, the ALWP and the CTIWP of the EBMT

Combination of radiotherapy and vaccination overcomes checkpoint blockade resistance

The genetic landscape of dural marginal zone lymphomas

BO-1055, a novel DNA cross-linking agent with remarkable low myelotoxicity shows potent activity in sarcoma models

Epithelial ovarian cancer-secreted exosomal miR-222-3p induces polarization of tumor-associated macrophages

Importance of the residue 190 on bactericidal activity of the bactericidal/permeability-increasing protein 5

Targeting glioma stem cells enhances anti-tumor effect of boron neutron capture therapy

Angiogenin contributes to bladder cancer tumorigenesis by DNMT3b-mediated MMP2 activation

Wnt-beta-catenin pathway signals metastasis-associated tumor cell phenotypes in triple negative breast cancers

Tunneling nanotube formation is stimulated by hypoxia in ovarian cancer cells

Epigenetic modifications promote the expression of the orphan nuclear receptor NR0B1 in human lung adenocarcinoma cells

Expression of the extracellular sulfatase SULF2 is associated with squamous cell carcinoma of the head and neck

The Hippo transducers TAZ/YAP and their target CTGF in male breast cancer

A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer

Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells

Orai1 promotes tumor progression by enhancing cancer stemness via NFAT signaling in oral/oropharyngeal squamous cell carcinoma

Xist reduction in breast cancer upregulates AKT phosphorylation via HDAC3-mediated repression of PHLPP1 expression

Human HLA-A*02:01/CHM1+ allo-restricted T cell receptor transgenic CD8+ T Cells specifically inhibit Ewing sarcoma growth in vitro and in vivo

Expression and functional characterization of CD33 transcript variants in human acute myeloid leukemia

The role of Wnt/β-catenin signaling pathway in melanoma epithelial-to-mesenchymal-like switching: evidences from patients-derived cell lines

The impact of intermittent versus continuous exposure to EGFR tyrosine kinase inhibitor on selection of EGFR T790M-mutant drug-resistant clones in a lung cancer cell line carrying activating EGFR mutation

14,15-EET induces the infiltration and tumor-promoting function of neutrophils to trigger the growth of minimal dormant metastases

NEAT1 upregulates EGCG-induced CTR1 to enhance cisplatin sensitivity in lung cancer cells

Anti-tax interacting protein-1 (TIP-1) monoclonal antibody targets human cancers

E-cadherin re-expression shows in vivo evidence for mesenchymal to epithelial transition in clonal metastatic breast tumor cells

PIK3C2A mRNA functions as a miR-124 sponge to facilitate CD151 expression and enhance malignancy of hepatocellular carcinoma cells

Sirt3-mediated mitophagy protects tumor cells against apoptosis under hypoxia

Eukaryotic translation initiation factor 3B accelerates the progression of esophageal squamous cell carcinoma by activating β-catenin signaling pathway

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen

Loss of miR-1258 contributes to carcinogenesis and progression of liver cancer through targeting CDC28 protein kinase regulatory subunit 1B

Urine gamma-synuclein as a biomarker for the diagnosis of bladder cancer

Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs

Mediation of the malignant biological characteristics of gastric cancer cells by the methylated CpG islands in RNF180 DNA promoter

(-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma

MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis

BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma

HIF2α/EFEMP1 cascade mediates hypoxic effects on breast cancer stem cell hierarchy

The transcription factor FOXN3 inhibits cell proliferation by downregulating E2F5 expression in hepatocellular carcinoma cells

Evaluation and characterization of anti-RalA autoantibody as a potential serum biomarker in human prostate cancer

Targeted next-generation sequencing of dedifferentiated chondrosarcoma in the skull base reveals combined TP53 and PTEN mutations with increased proliferation index, an implication for pathogenesis

Extracellular vesicles secreted by highly metastatic clonal variants of osteosarcoma preferentially localize to the lungs and induce metastatic behaviour in poorly metastatic clones

Long noncoding RNA CPS1-IT1 suppresses the metastasis of hepatocellular carcinoma by regulating HIF-1α activity and inhibiting epithelial-mesenchymal transition

Profiling the dynamic expression of checkpoint molecules on cytokine-induced killer cells from non-small-cell lung cancer patients

Multi-targeting NGR-modified liposomes recognizing glioma tumor cells and vasculogenic mimicry for improving anti-glioma therapy

Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1

Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression

The association between BMI and gallbladder cancer risk: a meta-analysis

The prognostic value of lymph nodes count on survival of patients with node-negative gastric cancer

Blocking the PAH2 domain of Sin3A inhibits tumorigenesis and confers retinoid sensitivity in triple negative breast cancer

Polymorphisms in TIM-3 and breast cancer susceptibility in Chinese women: A case-control study

Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism

Redox-sensitive MAPK and Notch3 regulate fibroblast differentiation and activation: a dual role of ERK1/2

Dual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer

Combination of gemcitabine-containing magnetoliposome and oxaliplatin-containing magnetoliposome in breast cancer treatment: A possible mechanism with potential for clinical application

AKR1B10 promotes breast cancer metastasis through integrin α5/δ-catenin mediated FAK/Src/Rac1 signaling pathway

IRE1α inhibition by natural compound genipin on tumour associated macrophages reduces growth of hepatocellular carcinoma

Aberrant methylation-mediated silencing of microRNAs contributes to HPV-induced anchorage independence

ER stress in temozolomide-treated glioblastomas interferes with DNA repair and induces apoptosis

Long noncoding RNA RP11-838N2.4 enhances the cytotoxic effects of temozolomide by inhibiting the functions of miR-10a in glioblastoma cell lines

Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells

Quantitative proteomics reveals that distant recurrence-associated protein R-Ras and Transgelin predict post-surgical survival in patients with Stage III colorectal cancer

Whole-exome sequencing to identify somatic mutations in peritoneal metastatic gastric adenocarcinoma: A preliminary study

Ellagitannin-rich cloudberry inhibits hepatocyte growth factor induced cell migration and phosphatidylinositol 3-kinase/AKT activation in colon carcinoma cells and tumors in Min mice

KCNN4 and S100A14 act as predictors of recurrence in optimally debulked patients with serous ovarian cancer

Quantitative in vivo optical tomography of cancer progression & vasculature development in adult zebrafish

Human pluripotent stem cell (PSC)-derived mesenchymal stem cells (MSCs) show potent neurogenic capacity which is enhanced with cytoskeletal rearrangement

MLLT11/AF1q boosts oncogenic STAT3 activity through Src-PDGFR tyrosine kinase signaling

Crucial factors of the inflammatory microenvironment (IL-1β/ TNF-α/TIMP-1) promote the maintenance of the malignant hemopoietic clone of myelofibrosis: an in vitro study

Demonstration of potential link between Helicobacter pylori related promoter CpG island methylation and telomere shortening in human gastric mucosa

BET inhibition as a new strategy for the treatment of gastric cancer

MDM2 knockdown mediated by a triazine-modified dendrimer in the treatment of non-small cell lung cancer

MiR-422a promotes loco-regional recurrence by targeting NT5E/CD73 in head and neck squamous cell carcinoma

Meta-analysis of the efficacy of the pretreatment neutrophil-to-lymphocyte ratio as a predictor of prognosis in renal carcinoma patients receiving tyrosine kinase inhibitors

Increased expression of SKP2 is an independent predictor of locoregional recurrence in cervical cancer via promoting DNA-damage response after irradiation

Cyr61 and YB-1 are novel interacting partners of uPAR and elevate the malignancy of triple-negative breast cancer

Hepatitis B virus genotypes, expression quantitative trait loci for ZNRD1-AS1 and their interactions in hepatocellular carcinoma

Reduced genomic tumor heterogeneity after neoadjuvant chemotherapy is related to favorable outcome in patients with esophageal adenocarcinoma

Breast cancer subtype dictates DNA methylation and ALDH1A3-mediated expression of tumor suppressor RARRES1

UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response

Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK

Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation

Aquaporin 9 inhibits hepatocellular carcinoma through up-regulating FOXO1 expression

Inhibition of histone deacetylases induces formation of multipolar spindles and subsequent p53-dependent apoptosis in nasopharyngeal carcinoma cells

Systemic immune-inflammation index, thymidine phosphorylase and survival of localized gastric cancer patients after curative resection

Missense mutations in the TP53 DNA-binding domain predict outcomes in patients with advanced oral cavity squamous cell carcinoma

Multiple-level validation identifies PARK2 in the development of lung cancer and chronic obstructive pulmonary disease

Dual-timing PSA as a biomarker for patients with salvage intensity modulated radiation therapy for biochemical failure after radical prostatectomy

Telomeric repeat-binding factor 2: a marker for survival and anti-EGFR efficacy in oral carcinoma

miR-22 inhibits tumor growth and metastasis by targeting ATP citrate lyase: evidence in osteosarcoma, prostate cancer, cervical cancer and lung cancer

MicroRNA-187 inhibits tumor growth and invasion by directly targeting CD276 in colorectal cancer

p63α modulates c-Myc activity via direct interaction and regulation of MM1 protein stability

Tumor-infiltrating lymphocytes in breast cancer predict the response to chemotherapy and survival outcome: A meta-analysis

A recombinant chimeric protein specifically induces mutant KRAS degradation and potently inhibits pancreatic tumor growth

iHyd-PseCp: Identify hydroxyproline and hydroxylysine in proteins by incorporating sequence-coupled effects into general PseAAC

Molecular driver alterations and their clinical relevance in cancer of unknown primary site

Study of single nucleotide polymorphisms of FBW7 and its substrate genes revealed a predictive factor for paclitaxel plus cisplatin chemotherapy in Chinese patients with advanced esophageal squamous cell carcinoma

Involvement of IL-10 and TGF-β in HLA-E-mediated neuroblastoma migration and invasion

Linking microsomal prostaglandin E synthase-1/PGE-2 pathway with miR-15a and -186 expression: Novel mechanism of VEGF modulation in prostate cancer

HMGA2 sustains self-renewal and invasiveness of glioma-initiating cells

Novel histopathologic feature identified through image analysis augments stage II colorectal cancer clinical reporting

Evaluation of the prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers

Identification of Glypican-3 as a potential metastasis suppressor gene in gastric cancer

SPANXA suppresses EMT by inhibiting c-JUN/SNAI2 signaling in lung adenocarcinoma

Prevention of pancreatic cancer in a hamster model by cAMP decrease

Long non-coding RNA UCA1 is a predictive biomarker of cancer

Down regulation of Chk1 by p53 plays a role in synergistic induction of apoptosis by chemotherapeutics and inhibitors for Jak2 or BCR/ABL in hematopoietic cells

Prostate tumor-induced angiogenesis is blocked by exosomes derived from menstrual stem cells through the inhibition of reactive oxygen species

Infiltrating macrophages increase RCC epithelial mesenchymal transition (EMT) and stem cell-like populations via AKT and mTOR signaling

High expression of TROP2 characterizes different cell subpopulations in androgen-sensitive and androgen-independent prostate cancer cells

Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer

Onco-miR-130 promotes cell proliferation and migration by targeting TGFβR2 in gastric cancer

TGF-β1 contributes to CD8⁺ Treg induction through p38 MAPK signaling in ovarian cancer microenvironment

Safety and efficacy profile of lenvatinib in cancer therapy: a systematic review and meta-analysis

The long non-coding RNA HOTAIR increases tumour growth and invasion in cervical cancer by targeting the Notch pathway

Activation of PPARγ suppresses proliferation and induces apoptosis of esophageal cancer cells by inhibiting TLR4-dependent MAPK pathway

Circulating cell-free DNA as a prognostic and predictive biomarker in non-small cell lung cancer

O-linked N-acetylglucosamine transferase promotes cervical cancer tumorigenesis through human papillomaviruses E6 and E7 oncogenes

Comprehensive expression profiles of gastric cancer molecular subtypes by immunohistochemistry: implications for individualized therapy

Convergent evidence from systematic analysis of GWAS revealed genetic basis of esophageal cancer

Piezo2 protein: A novel regulator of tumor angiogenesis and hyperpermeability

Maturation of dendritic cells by pullulan promotes anti-cancer effect

Biomarker quantification by multiplexed quantum dot technology for predicting lymph node metastasis and prognosis in head and neck cancer

Concurrent cisplatin and 5-fluorouracil versus concurrent cisplatin and docetaxel with radiotherapy for esophageal squamous cell carcinoma: a propensity score-matched analysis

Survival of patients with symptom- and screening-detected colorectal cancer

Combined sequential use of HAP and ART scores to predict survival outcome and treatment failure following chemoembolization in hepatocellular carcinoma: a multi-center comparative study

Molecular and clinical significance of fibroblast growth factor 2 (FGF2 /bFGF) in malignancies of solid and hematological cancers for personalized therapies

Cell apoptosis, autophagy and necroptosis in osteosarcoma treatment

From kinetics and cellular cooperations to cancer immunotherapies

Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its development

A systematic review on in vitro 3D bone metastases models: A new horizon to recapitulate the native clinical scenario?

Molecules that target nucleophosmin for cancer treatment: an update

How do the results of the RADIANT trials impact on the management of NET patients? A systematic review of published studies

Ubiquitin-specific peptidase 22 functions and its involvement in disease

Wait-and-see treatment strategies for rectal cancer patients with clinical complete response after neoadjuvant chemoradiotherapy: a systematic review and meta-analysis