The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells

Heme oxygenase-1 nuclear translocation regulates bortezomib-induced cytotoxicity and mediates genomic instability in myeloma cells

Betacellulin induces Slug-mediated down-regulation of E-cadherin and cell migration in ovarian cancer cells

Brachyury as a potential modulator of androgen receptor activity and a key player in therapy resistance in prostate cancer

Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice

Mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia: a report from the Italian AIEOP study group

Integrative transcriptome analysis identifies deregulated microRNA-transcription factor networks in lung adenocarcinoma

Cinobufagin inhibits tumor growth by inducing intrinsic apoptosis through AKT signaling pathway in human nonsmall cell lung cancer cells

Western diet enhances benzo(a)pyrene-induced colon tumorigenesis in a polyposis in rat coli (PIRC) rat model of colon cancer

Primary versus castration-resistant prostate cancer: modeling through novel murine prostate cancer cell lines

Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells

shRNA targeting long non-coding RNA CCAT2 controlled by tetracycline-inducible system inhibits progression of bladder cancer cells

Autophagy-related cell death by pan-histone deacetylase inhibition in liver cancer

Brigatinib, an anaplastic lymphoma kinase inhibitor, abrogates activity and growth in ALK-positive neuroblastoma cells, Drosophila and mice

LOX is a novel mitotic spindle-associated protein essential for mitosis

Chemotherapy-induced uridine diphosphate release promotes breast cancer metastasis through P2Y₆ activation

CD133⁺ cancer stem-like cells promote migration and invasion of salivary adenoid cystic carcinoma by inducing vasculogenic mimicry formation

Targeting of short TRPM8 isoforms induces 4TM-TRPM8-dependent apoptosis in prostate cancer cells

SOCS-1 rescues IL-1β-mediated suppression of epithelial sodium channel in mouse lung epithelial cells via ASK-1

Efficacy of combined gemcitabine, oxaliplatin and pegaspargase (P-gemox regimen) in patients with newly diagnosed advanced-stage or relapsed/refractory extranodal NK/T-cell lymphoma

Therapeutic potential and functional interaction of carfilzomib and vorinostat in T-cell leukemia/lymphoma

Magnolol and honokiol exert a synergistic anti-tumor effect through autophagy and apoptosis in human glioblastomas

Dual inhibition of AKT/FLT3-ITD by A674563 overcomes FLT3 ligand-induced drug resistance in FLT3-ITD positive AML

Protective effects of alpha lipoic acid on radiation-induced salivary gland injury in rats

Circulating cell-free DNA has a high degree of specificity to detect exon 19 deletions and the single-point substitution mutation L858R in non-small cell lung cancer

Mitochondrial DNA content in breast cancer: Impact on in vitro and in vivo phenotype and patient prognosis

Which patients with para-aortic lymph node (LN16) metastasis will truly benefit from curative pancreaticoduodenectomy for pancreatic head cancer?

Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer

CRKL mediates EML4-ALK signaling and is a potential therapeutic target for ALK-rearranged lung adenocarcinoma

Whole exome sequencing of urachal adenocarcinoma reveals recurrent NF1 mutations

Silencing homeobox C6 inhibits colorectal cancer cell proliferation

s-SHIP expression identifies a subset of murine basal prostate cells as neonatal stem cells

Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cells

SIRT1 facilitates hepatocellular carcinoma metastasis by promoting PGC-1α-mediated mitochondrial biogenesis

MiR-320a inhibits gastric carcinoma by targeting activity in the FoxM1-P27^KIP1 axis

Comparative proteomics of exosomes secreted by tumoral Jurkat T cells and normal human T cell blasts unravels a potential tumorigenic role for valosin-containing protein

Nuclear factor one B (NFIB) encodes a subtype-specific tumour suppressor in glioblastoma

Can the microRNA expression profile help to identify novel targets for zoledronic acid in breast cancer?

Reduced expression of CD109 in tumor-associated endothelial cells promotes tumor progression by paracrine interleukin-8 in hepatocellular carcinoma

GP73-regulated oncolytic adenoviruses possess potent killing effect on human liver cancer stem-like cells

Wip1 suppresses ovarian cancer metastasis through the ATM/AKT/Snail mediated signaling

Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/β-catenin signaling

JMJD3 promotes survival of diffuse large B-cell lymphoma subtypes via distinct mechanisms

Anti-miR delivery strategies to bypass the blood-brain barrier in glioblastoma therapy

The role of histological subtype in hormone receptor positive metastatic breast cancer: similar survival but different therapeutic approaches

Lymph node ratio may predict the benefit of postoperative radiotherapy in node-positive cervical cancer

Pinin facilitated proliferation and metastasis of colorectal cancer through activating EGFR/ERK signaling pathway

The cellular distribution of Na⁺/H⁺ exchanger regulatory factor 1 is determined by the PDZ-I domain and regulates the malignant progression of breast cancer

NMR-based fecal metabolomics fingerprinting as predictors of earlier diagnosis in patients with colorectal cancer

Human growth hormone and human prolactin function as autocrine/paracrine promoters of progression of hepatocellular carcinoma

B7-H3 as a promising target for cytotoxicity T cell in human cancer therapy

Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling

Knockdown of CMTM3 promotes metastasis of gastric cancer via the STAT3/Twist1/EMT signaling pathway

Targeting of Chk2 as a countermeasure to dose-limiting toxicity triggered by topoisomerase-II (TOP2) poisons

Deciphering the role of nuclear and cytoplasmic IKKα in skin cancer

Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis

Benzyl butyl phthalate promotes breast cancer stem cell expansion via SPHK1/S1P/S1PR3 signaling

Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging

Ninjurin1 inhibits colitis-mediated colon cancer development and growth by suppression of macrophage infiltration through repression of FAK signaling

Downregulation of amplified in breast cancer 1 contributes to the anti-tumor effects of sorafenib on human hepatocellular carcinoma

TREM-2 serves as a negative immune regulator through Syk pathway in an IL-10 dependent manner in lung cancer

Colorectal cancer cells display chaperone dependency for the unconventional prefoldin URI1

X66, a novel N-terminal heat shock protein 90 inhibitor, exerts antitumor effects without induction of heat shock response

The La protein counteracts cisplatin-induced cell death by stimulating protein synthesis of anti-apoptotic factor Bcl2

Gene expression profiling of normal thyroid tissue from patients with thyroid carcinoma

The transcription factor RUNX2 regulates receptor tyrosine kinase expression in melanoma

Nomograms for predicting long-term survival in patients with non-metastatic nasopharyngeal carcinoma in an endemic area

Relapse-related long non-coding RNA signature to improve prognosis prediction of lung adenocarcinoma

Induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in stage III-IVb nasopharyngeal carcinoma patients with Epstein-Barr virus DNA ≥4000 copies/ml: a matched study

Suppression of epithelial-mesenchymal transition in hepatocellular carcinoma cells by Krüppel-like factor 4

Genetic changes of non-small cell lung cancer under neoadjuvant therapy

Two variants on T2DM susceptible gene HHEX are associated with CRC risk in a Chinese population

Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas

Notch signaling: its roles and therapeutic potential in hematological malignancies

shRNA-armed conditionally replicative adenoviruses: a promising approach for cancer therapy

Emerging preclinical pharmacological targets for Parkinson’s disease

CHIP: A new modulator of human malignant disorders