The anti-aging effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strain

Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes

ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and c-Myc to reduce breast cancer proliferation

Colorectal cancer cell-derived extracellular vesicles induce phenotypic alteration of T cells into tumor-growth supporting cells with transforming growth factor-β1-mediated suppression

Efficacy and safety of sorafenib versus sunitinib as first-line treatment in patients with metastatic renal cell carcinoma: largest single-center retrospective analysis

mTOR inhibitors, a new era for metastatic luminal HER2-negative breast cancer? A systematic review and a meta-analysis of randomized trials

Stability of the hybrid epithelial/mesenchymal phenotype

The angiogenesis in decellularized scaffold-mediated the renal regeneration

Novel signaling collaboration between TGF-β and adaptor protein Crk facilitates EMT in human lung cancer

Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1α: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma

Mitophagy in TGEV infection counteracts oxidative stress and apoptosis

The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma

Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cells

Loss of PIG3 increases HIF-1α level by promoting protein synthesis via mTOR pathway in renal cell carcinoma cells

The degree of intratumor mutational heterogeneity varies by primary tumor sub-site

Pretreatment magnetic resonance imaging of regional lymph nodes with carcinoembryonic antigen in prediction of synchronous distant metastasis in patients with rectal cancer

Comparative genomic analysis of primary tumors and metastases in breast cancer

Molecular classification of cancer with the 92-gene assay in cytology and limited tissue samples

Circulating tumor cells exhibit stem cell characteristics in an orthotopic mouse model of colorectal cancer

The feasibility of ¹⁸F-AlF-NOTA-PRGD2 PET/CT for monitoring early response of Endostar antiangiogenic therapy in human nasopharyngeal carcinoma xenograft model compared with ¹⁸F-FDG

High CD3+ and CD34+ peripheral blood stem cell grafts content is associated with increased risk of graft-versus-host disease without beneficial effect on disease control after reduced-intensity conditioning allogeneic transplantation from matched unrelated donors for acute myeloid leukemia — an analysis from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

Genistein mediates the selective radiosensitizing effect in NSCLC A549 cells via inhibiting methylation of the keap1 gene promoter region

LGR5 expression is controled by IKKα in basal cell carcinoma through activating STAT3 signaling pathway

The phosphatase of regenerating liver-3 (PRL-3) is important for IL-6-mediated survival of myeloma cells

Pre-diagnostic leukocyte mitochondrial DNA copy number and risk of lung cancer

Glucocorticoid receptor beta increases migration of human bladder cancer cells

Targeting estrogen/estrogen receptor alpha enhances Bacillus Calmette-Guérin efficacy in bladder cancer

Inhibition of autophagy potentiates anticancer property of 20(S)-ginsenoside Rh2 by promoting mitochondria-dependent apoptosis in human acute lymphoblastic leukaemia cells

Period2 downregulation inhibits glioma cell apoptosis by activating the MDM2-TP53 pathway

Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: identification of functional disparities between azacytidine and decitabine

Chronic arsenic trioxide exposure leads to enhanced aggressiveness via Met oncogene addiction in cancer cells

Neuroendocrine-like cells -derived CXCL10 and CXCL11 induce the infiltration of tumor-associated macrophage leading to the poor prognosis of colorectal cancer

Apoptosis signal-regulating kinase 1 mediates the inhibitory effect of hepatocyte nuclear factor-4α on hepatocellular carcinoma

p21-activated kinase 1 (PAK1) expression correlates with prognosis in solid tumors: A systematic review and meta-analysis

Human papillomavirus oncogenic E6 protein regulates human β-defensin 3 (hBD3) expression via the tumor suppressor protein p53

MicroRNA-31 functions as a tumor suppressor and increases sensitivity to mitomycin-C in urothelial bladder cancer by targeting integrin α5

Post-treatment serum lactic dehydrogenase as a predictive indicator for distant metastasis and survival of patients with nasopharyngeal carcinoma

Transcriptome-wide analysis of compression-induced microRNA expression alteration in breast cancer for mining therapeutic targets

Effect of IL-7 and IL-15 on T cell phenotype in myelodysplastic syndromes

Inhibition of skeletal growth of human prostate cancer by the combination of docetaxel and BKM1644: an aminobisphosphonate derivative

Pyrosequencing quantified methylation level of BRCA1 promoter as prognostic factor for survival in breast cancer patient

Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor

Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice

The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker

Migration-inducing gene 7 promotes tumorigenesis and angiogenesis and independently predicts poor prognosis of epithelial ovarian cancer

RSK-mediated down-regulation of PDCD4 is required for proliferation, survival, and migration in a model of triple-negative breast cancer

Lung cancer-derived galectin-1 contributes to cancer associated fibroblast-mediated cancer progression and immune suppression through TDO2/kynurenine axis

ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation

A double-negative feedback loop between E2F3b and miR- 200b regulates docetaxel chemosensitivity of human lung adenocarcinoma cells

Activation of epithelial proliferation induced by Eimeria acervulina infection in the duodenum may be associated with cholesterol metabolism

Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin

Improving molecular diagnosis of Chinese patients with Charcot-Marie-Tooth by targeted next-generation sequencing and functional analysis

Single-nucleotide polymorphisms in PSCA and the risk of breast cancer in a Chinese population

Identification of granulocytic myeloid-derived suppressor cells (G-MDSCs) in the peripheral blood of Hodgkin and non-Hodgkin lymphoma patients

Lysine demethylase 2A promotes stemness and angiogenesis of breast cancer by upregulating Jagged1

Repressor and activator protein accelerates hepatic ischemia reperfusion injury by promoting neutrophil inflammatory response

Resistance of ground glass hepatocytes to oral antivirals in chronic hepatitis B patients and implication for the development of hepatocellular carcinoma

The roles of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in malignancy of human endometrial cancer cells

BCL2-BH4 antagonist BDA-366 suppresses human myeloma growth

A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases

Downregulation of LncRNA GAS5 causes trastuzumab resistance in breast cancer

CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway

Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies

Icariside II, a natural mTOR inhibitor, disrupts aberrant energy homeostasis via suppressing mTORC1-4E-BP1 axis in sarcoma cells

Telomerase reverse transcriptase promoter mutations in hepatitis B virus-associated hepatocellular carcinoma

Comparison of the RECIST and PERCIST criteria in solid tumors: a pooled analysis and review

Spatial memory impairment by TRPC1 depletion is ameliorated by environmental enrichment

REG4 promotes peritoneal metastasis of gastric cancer through GPR37

Read-through transcripts in normal human lung parenchyma are down-regulated in lung adenocarcinoma

Comprehensive analysis of genome-wide DNA methylation across human polycystic ovary syndrome ovary granulosa cell

The etiology of Ebola virus disease-like illnesses in Ebola virusnegative patients from Sierra Leone

Behavioral alterations following blood-brain barrier disruption stimulated by focused ultrasound

Pseudotyped αvβ6 integrin-targeted adenovirus vectors for ovarian cancer therapies

Parecoxib prevents complications in hepatocellular carcinoma patients receiving hepatic transarterial chemoembolization: a prospective score-matched cohort study

High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition

KDM1A promotes tumor cell invasion by silencing TIMP3 in non-small cell lung cancer cells

Interaction of KLF6 and Sp1 regulates basigin-2 expression mediated proliferation, invasion and metastasis in hepatocellular carcinoma

eNOS polymorphisms and clinical outcome in advanced HCC patients receiving sorafenib: final results of the ePHAS study

MicroRNA-452 promotes stem-like cells of hepatocellular carcinoma by inhibiting Sox7 involving Wnt/β-catenin signaling pathway

Hepatitis B virus X protein up-regulates C4b-binding protein α through activating transcription factor Sp1 in protection of hepatoma cells from complement attack

Distinct epigenetic signatures elucidate enhancer-gene relationships that delineate CIMP and non-CIMP colorectal cancers

Age-related effects of X-ray irradiation on mouse hippocampus

Immune-mediated liver injury of the cancer therapeutic antibody catumaxomab targeting EpCAM, CD3 and Fcγ receptors

Tumor-suppressive miR-218-5p inhibits cancer cell proliferation and migration via EGFR in non-small cell lung cancer

Genetic profile of GNAQ-mutated blue melanocytic neoplasms reveals mutations in genes linked to genomic instability and the PI3K pathway

Differential effects of lenalidomide during plasma cell differentiation

Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population

Evaluating the diagnostic and prognostic value of circulating cathepsin S in gastric cancer

Changes in plasma chemokine C-C motif ligand 2 levels during treatment with eicosapentaenoic acid predict outcome in patients undergoing surgery for colorectal cancer liver metastasis

Non-invasive assessment of inter-and intrapatient variability of integrin expression in metastasized prostate cancer by PET

Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

Hypoxia primes human normal prostate epithelial cells and cancer cell lines for the NLRP3 and AIM2 inflammasome activation

miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma

Sp1 and COX2 expression is positively correlated with a poor prognosis in pancreatic ductal adenocarcinoma

PEDF inhibits pancreatic tumorigenesis by attenuating the fibro-inflammatory reaction

Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis

Preclinical evaluation of the anti-tumor effects of the natural isoflavone genistein in two xenograft mouse models monitored by [¹⁸F]FDG, [¹⁸F]FLT, and [⁶⁴Cu]NODAGA-cetuximab small animal PET

Gene therapy for colorectal cancer using adenovirus-mediated full-length antibody, cetuximab

The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance

Apoptotic transition of senescent cells accompanied with mitochondrial hyper-function

A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression

Down-regulation of LAPTM5 in human cancer cells

Histone deacetylase inhibitor-induced cancer stem cells exhibit high pentose phosphate pathway metabolism

c-Src activation promotes nasopharyngeal carcinoma metastasis by inducing the epithelial-mesenchymal transition via PI3K/Akt signaling pathway: a new and promising target for NPC

Mutation profiling in chinese patients with metastatic colorectal cancer and its correlation with clinicopathological features and anti-EGFR treatment response

Selenium-enriched polysaccharides from Pyracantha fortuneana (Se-PFPs) inhibit the growth and invasive potential of ovarian cancer cells through inhibiting β-catenin signaling

Low expression of protocadherin7 (PCDH7) is a potential prognostic biomarker for primary non-muscle invasive bladder cancer

Dual oncogenic and tumor suppressor roles of the promyelocytic leukemia gene in hepatocarcinogenesis associated with hepatitis B virus surface antigen

Radiotherapy dose led to a substantial prolongation of survival in patients with locally advanced rectosigmoid junction cancer: a large population based study

MiR-34a-5p promotes the multi-drug resistance of osteosarcoma by targeting the CD117 gene

mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency

Protein profiling of alpha-fetoprotein producing gastric adenocarcinoma

Regulation of UHRF1 by dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p): inhibition of bladder cancer cell aggressiveness

ProNGF is a potential diagnostic biomarker for thyroid cancer

Yin Yang-1 increases apoptosis through Bax activation in pancreatic cancer cells

A loss-of-function genetic screening identifies novel mediators of thyroid cancer cell viability

Prediction of survival prognosis of non-small cell lung cancer by APE1 through regulation of epithelial-mesenchymal transition

PRSS8 methylation and its significance in esophageal squamous cell carcinoma

Prospective validation of microRNA signatures for detecting pancreatic malignant transformation in endoscopic-ultrasound guided fine-needle aspiration biopsies

Intratumoral expression of CCR3 in breast cancer is associated with improved relapse-free survival in luminal-like disease

TRIM29 overexpression is associated with poor prognosis and promotes tumor progression by activating Wnt/β-catenin pathway in cervical cancer

ΔNp63α induces the expression of FAT2 and Slug to promote tumor invasion

Changes in cytochrome P450s-mediated drug clearance in patients with hepatocellular carcinoma in vitro and in vivo: a bottom-up approach

The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury

Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate

Serum miR-125b is a non-invasive predictive biomarker of the pre-operative chemoradiotherapy responsiveness in patients with rectal adenocarcinoma

Tumour-specific triple-regulated oncolytic herpes virus to target glioma

A reciprocal regulatory circuit between CD44 and FGFR2 via c-myc controls gastric cancer cell growth

Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia

The RNA helicase A in malignant transformation

HMGA1-pseudogenes and cancer

Important roles of P2Y receptors in the inflammation and cancer of digestive system

Exosomes isolation and characterization in serum is feasible in non-small cell lung cancer patients: critical analysis of evidence and potential role in clinical practice