BAI1: from cancer to neurological disease

Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis

Serum HER2 levels are increased in cats with mammary carcinomas and predict tissue HER2 status

Improved muscle function and quality after diet intervention with leucine-enriched whey and antioxidants in antioxidant deficient aged mice

Tau accumulation impairs mitophagy via increasing mitochondrial membrane potential and reducing mitochondrial Parkin

Oral isoflavone supplementation on endometrial thickness: a meta-analysis of randomized placebo-controlled trials

The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling

C-phycocyanin protects against low fertility by inhibiting reactive oxygen species in aging mice

Genetic overlap between type 2 diabetes and major depressive disorder identified by bioinformatics analysis

Up-regulation of serotonin receptor 2B mRNA and protein in the peri-infarcted area of aged rats and stroke patients

Concordance of folate receptor-α expression between biopsy, primary tumor and metastasis in breast cancer and lung cancer patients

Distinct functions and regulation of epithelial progesterone receptor in the mouse cervix, vagina, and uterus

Emodin via colonic irrigation modulates gut microbiota and reduces uremic toxins in rats with chronic kidney disease

Mitochondrial reactive oxygen species-mediated NLRP3 inflammasome activation contributes to aldosterone-induced renal tubular cells injury

Nickel chloride (NiCl₂) induces endoplasmic reticulum (ER) stress by activating UPR pathways in the kidney of broiler chickens

MiR-128-2 inhibits common lymphoid progenitors from developing into progenitor B cells

FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype

Rainbow trout CK9, a CCL25-like ancient chemokine that attracts and regulates B cells and macrophages, the main antigen presenting cells in fish

T cells conditioned with MDSC show an increased anti-tumor activity after adoptive T cell based immunotherapy

Artificial antigen-presenting cells expressing AFP_158-166 peptide and interleukin-15 activate AFP-specific cytotoxic T lymphocytes

DARPP-32: from neurotransmission to cancer

Functional role of autophagy in gastric cancer

BRAF inhibitor resistance enhances vulnerability to arginine deprivation in melanoma

Increased hepatic receptor interacting protein kinase 3 expression due to impaired proteasomal functions contributes to alcohol-induced steatosis and liver injury

DDRI-9: a novel DNA damage response inhibitor that blocks mitotic progression

Mutanome and expression of immune response genes in microsatellite stable colon cancer

14-3-3σ regulation of and interaction with YAP1 in acquired gemcitabine resistance via promoting ribonucleotide reductase expression

Low tristetraprolin expression promotes cell proliferation and predicts poor patients outcome in pancreatic cancer

CD133 promotes gallbladder carcinoma cell migration through activating Akt phosphorylation

β₂-adrenogenic signaling regulates NNK-induced pancreatic cancer progression via upregulation of HIF-1α

Cell-surface markers for colon adenoma and adenocarcinoma

Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression

Role and mechanism of miR-222 in arsenic-transformed cells for inducing tumor growth

AMPK and PKA interaction in the regulation of survival of liver cancer cells subjected to glucose starvation

mDia1 regulates breast cancer invasion by controlling membrane type 1-matrix metalloproteinase localization

Melanin content in melanoma metastases affects the outcome of radiotherapy

Upregulated WDR26 serves as a scaffold to coordinate PI3K/ AKT pathway-driven breast cancer cell growth, migration, and invasion

Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-β-catenin axis

CEACAM1 and MICA as novel serum biomarkers in patients with acute and recurrent pericarditis

Tumor size is an independent risk predictor for metachronous colorectal cancer

PKCδ regulates integrin α_Vβ₃ expression and transformed growth of K-ras dependent lung cancer cells

The homing and inhibiting effects of hNSCs-BMP4 on human glioma stem cells

“Triple positive” early breast cancer: an observational multicenter retrospective analysis of outcome

Ultraviolet radiation-induced tumor necrosis factor alpha, which is linked to the development of cutaneous SCC, modulates differential epidermal microRNAs expression

Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling

Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways

Analysis of differential β variable region of T cell receptor expression and NAV3/TNFRSF1B gene mutation in mycosis fungoides

Loss of tumor suppressor Merlin results in aberrant activation of Wnt/β-catenin signaling in cancer

A network-based method for identifying prognostic gene modules in lung squamous carcinoma

PLA2G16 promotes osteosarcoma metastasis and drug resistance via the MAPK pathway

Stratifying diffuse large B-cell lymphoma patients treated with chemoimmunotherapy: GCB/non-GCB by immunohistochemistry is still a robust and feasible marker

EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells

Predicting hot spots in protein interfaces based on protrusion index, pseudo hydrophobicity and electron-ion interaction pseudopotential features

Mitotic cell death caused by follistatin-like 1 inhibition is associated with up-regulated Bim by inactivated Erk1/2 in human lung cancer cells

MACC1 mediates acetylcholine-induced invasion and migration by human gastric cancer cells

Serum sphingolipidomic analyses reveal an upregulation of C16- ceramide and sphingosine-1-phosphate in hepatocellular carcinoma

Deletion of IL-33R attenuates VEGF expression and enhances necrosis in mammary carcinoma

An EBV recombinant deleted for residues 130-159 in EBNA3C can deregulate p53/Mdm2 and Cyclin D1/CDK6 which results in apoptosis and reduced cell proliferation

Stereotactic radiation therapy for oligometastases or oligorecurrence within mediastinal lymph nodes

Pancreatic stellate cells contribute pancreatic cancer pain via activation of sHH signaling pathway

CHK1 regulates NF-κB signaling upon DNA damage in p53- deficient cells and associated tumor-derived microvesicles

Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor

Galectin signatures contribute to the heterogeneity of breast cancer and provide new prognostic information and therapeutic targets

Inhibition of protein kinase CK2 by CX-5011 counteracts imatinib-resistance preventing rpS6 phosphorylation in chronic myeloid leukaemia cells: new combined therapeutic strategies

The role and potential mechanisms of LncRNA-TATDN1 on metastasis and invasion of non-small cell lung cancer

Liver fatty acid-binding protein (L-FABP) promotes cellular angiogenesis and migration in hepatocellular carcinoma

MiR-206 inhibits HGF-induced epithelial-mesenchymal transition and angiogenesis in non-small cell lung cancer via c-Met /PI3k/ Akt/mTOR pathway

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models

Tumor deposits counted as positive lymph nodes in TNM staging for advanced colorectal cancer: a retrospective multicenter study

Dicer suppresses the malignant phenotype in VHL-deficient clear cell renal cell carcinoma by inhibiting HIF-2α

A novel double-negative feedback loop between miR-489 and the HER2-SHP2-MAPK signaling axis regulates breast cancer cell proliferation and tumor growth

A nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells

Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression

BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients

SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells

¹²⁵I brachytherapy in the palliation of painful bone metastases from lung cancer after failure or rejection of conventional treatments

Identification of FGF19 as a prognostic marker and potential driver gene of lung squamous cell carcinomas in Chinese smoking patients

Systematic characterization of lncRNAs’ cell-to-cell expression heterogeneity in glioblastoma cells

Nuclear heat shock protein 110 expression is associated with poor prognosis and chemotherapy resistance in gastric cancer

Preclinical evidence of multiple mechanisms underlying trastuzumab resistance in gastric cancer

Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response

Prognostic impact of serum and tissue MMP-9 in non-small cell lung cancer: a systematic review and meta-analysis

Dietary pterostilbene is a novel MTA1-targeted chemopreventive and therapeutic agent in prostate cancer

Detection of aberrant methylation of a six-gene panel in serum DNA for diagnosis of breast cancer

Cdc7 is a potent anti-cancer target in pancreatic cancer due to abrogation of the DNA origin activation checkpoint

Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blockade in a mouse orthotopic pancreatic tumour model

Amplexicaule A exerts anti-tumor effects by inducing apoptosis in human breast cancer

MMP2 and MMP9 serum levels are associated with favorable outcome in patients with inflammatory breast cancer treated with bevacizumab-based neoadjuvant chemotherapy in the BEVERLY-2 study

eIF3f reduces tumor growth by directly interrupting clusterin with anti-apoptotic property in cancer cells

Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models

Markers of fibroblast-rich tumor stroma and perivascular cells in serous ovarian cancer: Inter- and intra-patient heterogeneity and impact on survival

A pharmacokinetic and safety study of a fixed oral dose of enzastaurin HCl in native Chinese patients with refractory solid tumors and lymphoma

miR-342 overexpression results in a synthetic lethal phenotype in BRCA1-mutant HCC1937 breast cancer cells

Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease

Nek7 is overexpressed in hepatocellular carcinoma and promotes hepatocellular carcinoma cell proliferation in vitro and in vivo

Genetic scores based on risk-associated single nucleotide polymorphisms (SNPs) can reveal inherited risk of renal cell carcinoma

Overexpression of RPS27a contributes to enhanced chemoresistance of CML cells to imatinib by the transactivated STAT3

Butein inhibits cell proliferation and induces cell cycle arrest in acute lymphoblastic leukemia via FOXO3a/p27kip1 pathway

High expression of myoferlin is associated with poor outcome in oropharyngeal squamous cell carcinoma patients and is inversely associated with HPV-status

Langerhans cell histiocytosis in adults: a case report and review of the literature

Methylation-associated silencing of miR-200b facilitates human hepatocellular carcinoma progression by directly targeting BMI1

Suppression of B-Raf(V600E) cancers by MAPK hyper-activation

A short-term increase of the postoperative naturally circulating dendritic cells subsets in flurbiprofen-treated patients with esophageal carcinoma undergoing thoracic surgery

microRNAs are differentially regulated between MDM2-positive and negative malignant pleural mesothelioma

Androgen receptor in Sertoli cells regulates DNA double-strand break repair and chromosomal synapsis of spermatocytes partially through intercellular EGF-EGFR signaling

Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia

The survival benefit and safety of No. 12a lymphadenectomy for gastric cancer patients with distal or total gastrectomy

PDZ-binding kinase/T-LAK cell-originated protein kinase is a target of the fucoidan from brown alga Fucus evanescens in the prevention of EGF-induced neoplastic cell transformation and colon cancer growth

Diagnostic FDG and FDOPA positron emission tomography scans distinguish the genomic type and treatment outcome of neuroblastoma

Point-of-care test for cervical cancer in LMICs

CtBP1 associates metabolic syndrome and breast carcinogenesis targeting multiple miRNAs

PARP6 acts as a tumor suppressor via downregulating Survivin expression in colorectal cancer

An image guided small animal stereotactic radiotherapy system

High blood sugar levels significantly impact the prognosis of colorectal cancer patients through down-regulation of microRNA-16 by targeting Myb and VEGFR2

A combination of trastuzumab and BAG-1 inhibition synergistically targets HER2 positive breast cancer cells

CXCR4/CXCL12/CXCR7 axis is functional in neuroendocrine tumors and signals on mTOR

Comprehensive genetic testing identifies targetable genomic alterations in most patients with non-small cell lung cancer, specifically adenocarcinoma, single institute investigation

Radiation-induced brachial plexopathy in patients with nasopharyngeal carcinoma: a retrospective study

Exogenous p53 and ASPP2 expression enhances rAdV-TK/ GCV-induced death in hepatocellular carcinoma cells lacking functional p53

MiR-449a promotes breast cancer progression by targeting CRIP2

Smoking-promoted oxidative DNA damage response is highly correlated to lung carcinogenesis

SIRT2 inhibits non-small cell lung cancer cell growth through impairing Skp2-mediated p27 degradation

PTBP1-associated microRNA-1 and -133b suppress the Warburg effect in colorectal tumors

Genomic markers of panitumumab resistance including ERBB2/ HER2 in a phase II study of KRAS wild-type (wt) metastatic colorectal cancer (mCRC)

Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1

A wait-and-watch approach to small pancreatic neuroendocrine tumors: prognosis and survival

A single-nucleotide polymorphism in the 3′-UTR region of the adipocyte fatty acid binding protein 4 gene is associated with prognosis of triple-negative breast cancer

EBV reactivation as a target of luteolin to repress NPC tumorigenesis

ZLM-7 exhibits anti-angiogenic effects via impaired endothelial cell function and blockade of VEGF/VEGFR-2 signaling

Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: role of acid sphingomyelinase gene

Associations between polymorphisms of long non-coding RNA MEG3 and risk of colorectal cancer in Chinese

A rank-based transcriptional signature for predicting relapse risk of stage II colorectal cancer identified with proper data sources

Prognostic significance of bone marrow infiltration detected by PET-CT in newly diagnosed diffuse large B cell lymphoma

Survival following segmentectomy or lobectomy in elderly patients with early-stage lung cancer