Deinococcus radiodurans pprI expression enhances the radioresistance of eukaryotes

Downregulation of the stress-induced ligand ULBP1 following SV40 infection confers viral evasion from NK cell cytotoxicity

CCR5 knockout suppresses experimental autoimmune encephalomyelitis in C57BL/6 mice

Protein phosphatase, Mg²⁺/Mn²⁺-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infection

Potential therapeutic implications of IL-6/IL-6R/gp130-targeting agents in breast cancer

Regulation of androgen receptor splice variant AR3 by PCGEM1

Integrated experimental and simulation study of the response to sequential treatment with erlotinib and gemcitabine in pancreatic cancer

Isolation and characterization of renal cancer stem cells from patient-derived xenografts

CD68 and interleukin 13, prospective immune markers for esophageal squamous cell carcinoma prognosis prediction

A novel intracellular antibody against the E6 oncoprotein impairs growth of human papillomavirus 16-positive tumor cells in mouse models

Protective effect of α-lipoic acid against radiation-induced fibrosis in mice

The prognostic value of pretreatment CA-125 levels and CA-125 normalization in ovarian clear cell carcinoma: a two-academic-institute study

Implications of a peroxisome proliferator-activated receptor alpha (PPARα) ligand clofibrate in breast cancer

Meta-analysis of the association between selenium and gastric cancer risk

Sialylated immunoglobulin G can neutralize influenza virus infection through receptor mimicry

Allele-specific recognition by LILRB3 and LILRA6 of a cytokeratin 8 - associated ligand on necrotic glandular epithelial cells

CCL2-CCR2 axis promotes metastasis of nasopharyngeal carcinoma by activating ERK1/2-MMP2/9 pathway

Integrated transcriptomic and proteomic analysis identifies protein kinase CK2 as a key signaling node in an inflammatory cytokine network in ovarian cancer cells

Barrier-to-Autointegration Factor (BAF) involvement in prelamin A-related chromatin organization changes

Repulsive guidance molecule B inhibits metastasis and is associated with decreased mortality in non-small cell lung cancer

IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs

The E1B19K-deleted oncolytic adenovirus mutant AdΔ19K sensitizes pancreatic cancer cells to drug-induced DNA-damage by down-regulating Claspin and Mre11

Gamabufotalin triggers c-Myc degradation via induction of WWP2 in multiple myeloma cells

Ubiquitin ligase UBE3C promotes melanoma progression by increasing epithelial-mesenchymal transition in melanoma cells

Bladder cancer cells secrete while normal bladder cells express but do not secrete AGR2

Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers

Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation

LncRNA MT1JP functions as a tumor suppressor by interacting with TIAR to modulate the p53 pathway

Comparative efficacy and safety of first-line treatments in patients with metastatic renal cell cancer: a network meta-analysis based on phase 3 RCTs

ADP-ribosylation factor 1 expression regulates epithelial-mesenchymal transition and predicts poor clinical outcome in triple-negative breast cancer

High expression of RUNX1 is associated with poorer outcomes in cytogenetically normal acute myeloid leukemia

miR-486-5p expression pattern in esophageal squamous cell carcinoma, gastric cancer and its prognostic value

14-3-3ζ promotes hepatocellular carcinoma venous metastasis by modulating hypoxia-inducible factor-1α

SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells

Pathway of PPAR-gamma coactivators in thermogenesis: a pivotal traditional Chinese medicine-associated target for individualized treatment of rheumatoid arthritis

PD-L1 expression is associated with epithelial-mesenchymal transition in head and neck squamous cell carcinoma

miR-30e controls DNA damage-induced stress responses by modulating expression of the CDK inhibitor p21WAF1/CIP1 and caspase-3

Genetic variant rs4072037 of MUC1 and gastric cancer risk in an Eastern Chinese population

Prognostic significance and optimal cutoff of age in medullary thyroid cancer

A genetic variation in microRNA target site of ETS2 is associated with clinical outcomes of paclitaxel-cisplatin chemotherapy in non-small cell lung cancer

Efficacy of targeted AKT inhibition in genetically engineered mouse models of PTEN-deficient prostate cancer

Role of microRNAs in epigenetic silencing of the CHD5 tumor suppressor gene in neuroblastomas

Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXA

ZEB2 inhibits HBV transcription and replication by targeting its core promoter

Comprehensive analysis of lncRNA expression profiles and identification of functional lncRNAs in lung adenocarcinoma

Novel role of STRAP in progression and metastasis of colorectal cancer through Wnt/β-catenin signaling

Increased expression of SUMO1P3 predicts poor prognosis and promotes tumor growth and metastasis in bladder cancer

Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer

Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formation

Involvement of SULF2 in 𝛄-irradiation-induced invasion and resistance of cancer cells by inducing IL-6 expression

Genetic association study identifies a functional CNV in the WWOX gene contributes to the risk of intracranial aneurysms

Cinacalcet inhibits neuroblastoma tumor growth and upregulates cancer-testis antigens

IL-15 superagonist/IL-15RαSushi-Fc fusion complex (IL-15SA/IL-15RαSu-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-tumor activity against murine breast and colon carcinomas

Soluble Tie2 overrides the heightened invasion induced by anti-angiogenesis therapies in gliomas

Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer

Genetic mutations associated with metastatic clear cell renal cell carcinoma

Loss of large tumor suppressor 1 promotes growth and metastasis of gastric cancer cells through upregulation of the YAP signaling

Tongxinluo mitigates atherogenesis by regulating angiogenic factors and inhibiting vasa vasorum neovascularization in apolipoprotein E-deficient mice

miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation

Ribosomal protein L4 is a novel regulator of the MDM2-p53 loop

Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo

Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma

Elevated autocrine chemokine ligand 18 expression promotes oral cancer cell growth and invasion via Akt activation

Hepatocyte growth factor reduces sensitivity to the epidermal growth factor receptor-tyrosine kinase inhibitor, gefitinib, in lung adenocarcinoma cells harboring wild-type EGFR

A small molecule induces integrin β4 nuclear translocation and apoptosis selectively in cancer cells with high expression of integrin β4

ANXA11 regulates the tumorigenesis, lymph node metastasis and 5-fluorouracil sensitivity of murine hepatocarcinoma Hca-P cells by targeting c-Jun

Anti-cancer drug 3,3′-diindolylmethane activates Wnt4 signaling to enhance gastric cancer cell stemness and tumorigenesis

Cyclic AMP responsive element-binding protein promotes renal cell carcinoma proliferation probably via the expression of spindle and kinetochore-associated protein 2

Serum protein profiling using an aptamer array predicts clinical outcomes of stage IIA colon cancer: A leave-one-out crossvalidation

AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin

Identification of serologic biomarkers for predicting microvascular invasion in hepatocellular carcinoma

Epstein-Barr virus glycoprotein gH/gL antibodies complement IgA-viral capsid antigen for diagnosis of nasopharyngeal carcinoma

Detection of ATRX and IDH1-R132H immunohistochemistry in the progression of 211 paired gliomas

MicroRNA-199a and -214 as potential therapeutic targets in pancreatic stellate cells in pancreatic tumor

microRNA-206 impairs c-Myc-driven cancer in a synthetic lethal manner by directly inhibiting MAP3K13

Prospective evaluation of 64 serum autoantibodies as biomarkers for early detection of colorectal cancer in a true screening setting

Epigenetic inactivation of follistatin-like 1 mediates tumor immune evasion in nasopharyngeal carcinoma

VEGFR2 targeted antibody fused with MICA stimulates NKG2D mediated immunosurveillance and exhibits potent anti-tumor activity against breast cancer

MicroRNA-30a increases tight junction protein expression to suppress the epithelial-mesenchymal transition and metastasis by targeting Slug in breast cancer

A cancer-favoring oncolytic vaccinia virus shows enhanced suppression of stem-cell like colon cancer

Mapping of deletion breakpoints at the CDKN2A locus in melanoma: detection of MTAP-ANRIL fusion transcripts

Aberrant expression of nuclear HDAC3 and cytoplasmic CDH1 predict a poor prognosis for patients with pancreatic cancer

Carfilzomib potentiates CUDC-101-induced apoptosis in anaplastic thyroid cancer

Aquaporin 3 promotes the stem-like properties of gastric cancer cells via Wnt/GSK-3β/β-catenin pathway

Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes

miR-155-5p inhibition promotes the transition of bone marrow mesenchymal stem cells to gastric cancer tissue derived MSC-like cells via NF-κB p65 activation

Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma

Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation

Time trends of neonatal mortality by causes of death in Shenyang, 1997–2014

FOXM1 regulates expression of eukaryotic elongation factor 2 kinase and promotes proliferation, invasion and tumorgenesis of human triple negative breast cancer cells

p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGF-induced malignant cellular transformation

The targeted histone deacetylase inhibitor tefinostat (CHR-2845) shows selective in vitro efficacy in monocytoid-lineage leukaemias

Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells

miR-129-3p controls centrosome number in metastatic prostate cancer cells by repressing CP110

APE1-mediated DNA damage repair provides survival advantage for esophageal adenocarcinoma cells in response to acidic bile salts

MiR-652-3p is upregulated in non-small cell lung cancer and promotes proliferation and metastasis by directly targeting Lgl1

Radiation exposure, young age, and female gender are associated with high prevalence of RET/PTC1 and RET/PTC3 in papillary thyroid cancer: a meta-analysis

Preferential targeting of cancer stem cells in the radiosensitizing effect of ABT-737 on HNSCC

Significance of the NOR1-FOXA1/HDAC2-Slug regulatory network in epithelial-mesenchymal transition of tumor cells

Heterogeneous nuclear ribonucleoproteins A1 and A2 modulate expression of Tid1 isoforms and EGFR signaling in non-small cell lung cancer

Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo

hnRNP A1-mediated translational regulation of the G quadruplex-containing RON receptor tyrosine kinase mRNA linked to tumor progression

Cigarette smoking complements the prognostic value of baseline plasma Epstein-Barr virus deoxyribonucleic acid in patients with nasopharyngeal carcinoma undergoing intensity-modulated radiation therapy: a large-scale retrospective cohort study

Interaction of antihistaminic drugs with human translationally controlled tumor protein (TCTP) as novel approach for differentiation therapy

Thymic stromal lymphopoietin (TSLP) inhibits human colon tumor growth by promoting apoptosis of tumor cells

Exceptional antineoplastic activity of a dendritic-cell-targeted vaccine loaded with a Listeria peptide proposed against metastatic melanoma

STIM1 plays an important role in TGF-β-induced suppression of breast cancer cell proliferation

Areca nut components stimulate ADAM17, IL-1α, PGE2 and 8-isoprostane production in oral keratinocyte: role of reactive oxygen species, EGF and JAK signaling

iACP: a sequence-based tool for identifying anticancer peptides

ISG15 predicts poor prognosis and promotes cancer stem cell phenotype in nasopharyngeal carcinoma

Diagnostic and prognostic relevance of circulating exosomal miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer

ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells

Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity

High throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulator

Lymph nodes regression grade is a predictive marker for rectal cancer after neoadjuvant therapy and radical surgery

Tumor-associated antigen CAPERα and microvessel density in hepatocellular carcinoma

Cholesterol consumption and risk of endometrial cancer: a systematic review and dose-response meta-analysis of observational studies

Oroxylin A modulates mitochondrial function and apoptosis in human colon cancer cells by inducing mitochondrial translocation of wild-type p53

Chronic inflammation contributes to the development of hepatocellular carcinoma by decreasing miR-122 levels

Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination with fractionated radiotherapy

KU-0060648 inhibits hepatocellular carcinoma cells through DNA-PKcs-dependent and DNA-PKcs-independent mechanisms

Combination of metronomic cyclophosphamide and dietary intervention inhibits neuroblastoma growth in a CD1-nu mouse model

VEGF promotes gastric cancer development by upregulating CRMP4

Genomic characterization of patient-derived xenograft models established from fine needle aspirate biopsies of a primary pancreatic ductal adenocarcinoma and from patient-matched metastatic sites

Therapy of pancreatic cancer via an EphA2 receptor-targeted delivery of gemcitabine

Tumor-promoting function and prognostic significance of the RNA-binding protein T-cell intracellular antigen-1 in esophageal squamous cell carcinoma

N52 monodeamidated Bcl‑x_L shows impaired oncogenic properties in vivo and in vitro

MMP-13 is involved in oral cancer cell metastasis

ER maleate is a novel anticancer agent in oral cancer: implications for cancer therapy

Association of helicobacter pylori infection and chronic atrophic gastritis with risk of colonic, pancreatic and gastric cancer: A ten-year follow-up of the ESTHER cohort study

Combining BRAF inhibitor and anti PD-L1 antibody dramatically improves tumor regression and anti tumor immunity in an immunocompetent murine model of anaplastic thyroid cancer

TIKI2 is upregulated and plays an oncogenic role in renal cell carcinoma

Apatinib inhibits VEGF signaling and promotes apoptosis in intrahepatic cholangiocarcinoma

Combined analysis of circulating epithelial cells and serum thyroglobulin for distinguishing disease status of the patients with papillary thyroid carcinoma

MR imaging biomarkers for evaluating therapeutic effects shortly after near infrared photoimmunotherapy

Clinicopathologic distribution of KRAS and BRAF mutations in a Chinese population with colorectal cancer precursor lesions

Nomograms for predicting Gleason upgrading in a contemporary Chinese cohort receiving radical prostatectomy after extended prostate biopsy: development and internal validation