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Effects of MET aberrations on MCF-10A xenograft in hHGF transgenic mice. H&E for histological images from representative tumor from MET-WT: see Liu et al.
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Table of Contents
Editorial
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| Hyperactivated endolysosomal trafficking in melanoma |
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https://doi.org/10.18632/oncotarget.3141
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| 2583-2584 |
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| Aboutface on the metabolic side effects of rapamycin |
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https://doi.org/10.18632/oncotarget.3354
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| 2585-2586 |
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| Antibiotics for cancer therapy |
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https://doi.org/10.18632/oncotarget.3388
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| 2587-2588 |
Reviews
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| Cancer associated fibroblasts in hematological malignancies |
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https://doi.org/10.18632/oncotarget.2661
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| 2589-2603 |
Priority Research Papers
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| Functional consequence of the METT1010I polymorphism in breast cancer |
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https://doi.org/10.18632/oncotarget.3094
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| 2604-2614 |
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| Tumortargeting Salmonella typhimurium A1R arrests growth of breastcancer brain metastasis |
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https://doi.org/10.18632/oncotarget.2811
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| 2615-2622 |
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| Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo antibreast cancer activities and target validation |
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https://doi.org/10.18632/oncotarget.3098
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| 2623-2640 |
Research Papers: Gerotarget (Focus on Aging)
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| Age and metabolic risk factors associated with oxidatively damaged DNA in human peripheral blood mononuclear cells |
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https://doi.org/10.18632/oncotarget.3202
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| 2641-2653 |
Research Papers
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| ERp57 modulates STAT3 activity in radioresistant laryngeal cancer cells and serves as a prognostic marker for laryngeal cancer |
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https://doi.org/10.18632/oncotarget.3042
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| 2654-2666 |
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| Upregulation of CDK9 kinase activity and Mcl1 stability contributes to the acquired resistance to cyclindependent kinase inhibitors in leukemia |
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https://doi.org/10.18632/oncotarget.2096
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| 2667-2679 |
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| CBX7 and HMGA1b proteins act in opposite way on the regulation of the SPP1 gene expression |
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https://doi.org/10.18632/oncotarget.2777
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| 2680-2692 |
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| The translation inhibitor silvestrol exhibits direct antitumor activity while preserving innate and adaptive immunity against EBVdriven lymphoproliferative disease |
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https://doi.org/10.18632/oncotarget.2098
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| 2693-2708 |
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| A microRNA1280/JAG2 network comprises a novel biological target in highrisk medulloblastoma |
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https://doi.org/10.18632/oncotarget.2779
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| 2709-2724 |
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| The non glycanated endocan polypeptide slows tumor growth by inducing stromal inflammatory reaction |
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https://doi.org/10.18632/oncotarget.2614
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| 2725-2735 |
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| Upregulation of miR328 and inhibition of CREBDNAbinding activity are critical for resveratrolmediated suppression of matrix metalloproteinase2 and subsequent metastatic ability in human osteosarcomas |
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https://doi.org/10.18632/oncotarget.3088
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| 2736-2753 |
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| Mutational spectrum of adult TALL |
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https://doi.org/10.18632/oncotarget.2218
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| 2754-2766 |
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| Reduction of miR29c enhances pancreatic cancer cell migration and stem celllike phenotype |
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https://doi.org/10.18632/oncotarget.3089
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| 2767-2778 |
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| Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells |
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https://doi.org/10.18632/oncotarget.2995
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| 2779-2793 |
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| Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation |
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https://doi.org/10.18632/oncotarget.3056
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| 2794-2811 |
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| Novel antigens in nonsmall cell lung cancer: SP17 AKAP4 and PTTG1 are potential immunotherapeutic targets |
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https://doi.org/10.18632/oncotarget.2802
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| 2812-2826 |
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| Folatemediated mitochondrial targeting with doxorubicinpolyrotaxane nanoparticles overcomes multidrug resistance |
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https://doi.org/10.18632/oncotarget.3090
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| 2827-2842 |
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| MicroRNA 196B regulates FASmediated apoptosis in colorectal cancer cells |
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https://doi.org/10.18632/oncotarget.3066
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| 2843-2855 |
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| Chronic inflammationrelated DNA damage response: a driving force of gastric cardia carcinogenesis |
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https://doi.org/10.18632/oncotarget.3091
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| 2856-2864 |
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| NCL1 a highly selective lysinespecific demethylase 1 inhibitor suppresses prostate cancer without adverse effect |
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https://doi.org/10.18632/oncotarget.3067
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| 2865-2878 |
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| 12/15 lipoxygenase regulation of colorectal tumorigenesis is determined by the relative tumor levels of its metabolite 12HETE and 13HODE in animal models |
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https://doi.org/10.18632/oncotarget.2994
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| 2879-2888 |
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| Statininduced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation |
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https://doi.org/10.18632/oncotarget.3068
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| 2889-2902 |
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| Clusterin facilitates metastasis by EIF3I/Akt/MMP13 signaling in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.3093
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| 2903-2916 |
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| Downregulation of G9a triggers DNA damage response and inhibits colorectal cancer cells proliferation |
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https://doi.org/10.18632/oncotarget.2784
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| 2917-2927 |
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| Epigenetic reprogramming by tumorderived EZH2 gainoffunction mutations promotes aggressive 3D cell morphologies and enhances melanoma tumor growth |
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https://doi.org/10.18632/oncotarget.2758
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| 2928-2938 |
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| Cathelicidin an antimicrobial peptide produced by macrophages promotes colon cancer by activating the Wnt/βcatenin pathway |
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https://doi.org/10.18632/oncotarget.2845
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| 2939-2950 |
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| Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK AKT and HippoYAP pathways in cancer progression |
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https://doi.org/10.18632/oncotarget.3095
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| 2951-2965 |
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| miR638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy |
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https://doi.org/10.18632/oncotarget.3070
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| 2966-2980 |
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| Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ Tcell infiltration |
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https://doi.org/10.18632/oncotarget.3205
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| 2981-2991 |
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| Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins |
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https://doi.org/10.18632/oncotarget.2996
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| 2992-3002 |
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| TXNIP interaction with the Her1/2 pathway contributes to overall survival in breast cancer |
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https://doi.org/10.18632/oncotarget.3096
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| 3003-3012 |
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| Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression |
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https://doi.org/10.18632/oncotarget.3072
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| 3013-3032 |
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| Cyclin alterations in diverse cancers: Outcome and coamplification network |
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https://doi.org/10.18632/oncotarget.2848
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| 3033-3042 |
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| Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF1 activation in muscle |
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https://doi.org/10.18632/oncotarget.2812
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| 3043-3054 |
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| Lovastatin enhances adenovirusmediated TRAIL induced apoptosis by depleting cholesterol of lipid rafts and affecting CAR and death receptor expression of prostate cancer cells |
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https://doi.org/10.18632/oncotarget.3073
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| 3055-3070 |
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| Longterm treatment with imatinib results in profound mast cell deficiency in Ph+ chronic myeloid leukemia |
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https://doi.org/10.18632/oncotarget.3074
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| 3071-3084 |
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| Paracrine SDF1α signaling mediates the effects of PSCs on GEM chemoresistance through an IL6 autocrine loop in pancreatic cancer cells |
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https://doi.org/10.18632/oncotarget.3099
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| 3085-3097 |
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| Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma |
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https://doi.org/10.18632/oncotarget.3075
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| 3098-3110 |
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| Galectin1 is overexpressed in CD133+ human lung adenocarcinoma cells and promotes their growth and invasiveness |
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https://doi.org/10.18632/oncotarget.3076
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| 3111-3122 |
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| Slit2/Robo1 signaling promotes intestinal tumorigenesis through Srcmediated activation of the Wnt/βcatenin pathway |
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https://doi.org/10.18632/oncotarget.3060
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| 3123-3135 |
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| Top2a identifies and provides epigenetic rationale for novel combination therapeutic strategies for aggressive prostate cancer |
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https://doi.org/10.18632/oncotarget.3077
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| 3136-3146 |
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| Targeting miR381NEFL axis sensitizes glioblastoma cells to temozolomide by regulating stemness factors and multidrug resistance factors |
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https://doi.org/10.18632/oncotarget.3061
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| 3147-3164 |
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| Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target |
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https://doi.org/10.18632/oncotarget.3078
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| 3165-3177 |
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| Metformin inhibits tumor growth by regulating multiple miRNAs in human cholangiocarcinoma |
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https://doi.org/10.18632/oncotarget.3063
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| 3178-3194 |
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| Simultaneous targeting of androgen receptor AR and MAPKinteracting kinases MNKs by novel retinamides inhibits growth of human prostate cancer cell lines |
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https://doi.org/10.18632/oncotarget.3084
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| 3195-3210 |
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| MicroRNA93 activates cMet/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A |
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https://doi.org/10.18632/oncotarget.3085
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| 3211-3224 |
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| Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis |
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https://doi.org/10.18632/oncotarget.3064
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| 3225-3239 |
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| KITENIN promotes glioma invasiveness and progression associated with the induction of EMT and stemness markers |
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https://doi.org/10.18632/oncotarget.3087
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| 3240-3253 |
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| Dihydromyricetin prevents cardiotoxicity and enhances anticancer activity induced by adriamycin |
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https://doi.org/10.18632/oncotarget.2410
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| 3254-3267 |
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| MiR125b regulates epithelialmesenchymal transition via targeting Sema4C in paclitaxelresistant breast cancer cells |
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https://doi.org/10.18632/oncotarget.3065
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| 3268-3279 |
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| Biomolecular characterization of exosomes released from cancer stem cells: Possible implications for biomarker and treatment of cancer |
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https://doi.org/10.18632/oncotarget.2462
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| 3280-3291 |
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| MYC is a critical target of FBXW7 |
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https://doi.org/10.18632/oncotarget.3203
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| 3292-3305 |
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| Overexpression of IFNinduced protein with tetratricopeptide repeats 3 IFIT3 in pancreatic cancer: cellular “pseudoinflammation†contributing to an aggressive phenotype |
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https://doi.org/10.18632/oncotarget.2494
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| 3306-3318 |
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| In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma |
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https://doi.org/10.18632/oncotarget.3207
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| 3319-3334 |
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| Prognostic and therapeutic impact of RPN2mediated tumor malignancy in nonsmallcell lung cancer |
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https://doi.org/10.18632/oncotarget.2793
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| 3335-3345 |
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| Differential expression and prognostic value of the chemokine receptor CXCR4 in bronchopulmonary neuroendocrine neoplasms |
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https://doi.org/10.18632/oncotarget.3242
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| 3346-3358 |
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| Mechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastoma |
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https://doi.org/10.18632/oncotarget.3245
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| 3359-3374 |
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| A Golgibased KDELRdependent signalling pathway controls extracellular matrix degradation |
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https://doi.org/10.18632/oncotarget.3270
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| 3375-3393 |
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| Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma |
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https://doi.org/10.18632/oncotarget.2583
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| 3394-3408 |
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| FHIT lossinduced DNA damage creates optimal APOBEC substrates: Insights into APOBECmediated mutagenesis |
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https://doi.org/10.18632/oncotarget.2636
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| 3409-3419 |
Clinical Research Papers
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| Methylation of MGMT and ADAMTS14 in normal colon MUCOSA: biomarkers of a field defect for cancerization preferentially targeting elder AfricanAmericans |
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https://doi.org/10.18632/oncotarget.2852
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| 3420-3431 |
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| RMP predicts survival and adjuvant TACE response in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.3092
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| 3432-3442 |
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| Oncogenes and tumor suppressor genes in squamous cell carcinoma of the tongue in young patients |
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https://doi.org/10.18632/oncotarget.2850
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| 3443-3451 |
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| B7H1 and B7H3 are independent predictors of poor prognosis in patients with nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.3097
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| 3452-3461 |
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| Potential impact of human papilloma virus on survival of basaloid squamous carcinoma of the head and neck |
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https://doi.org/10.18632/oncotarget.3062
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| 3462-3470 |
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