- Editorial: Immunology
- Priority Research Papers
- Research Papers: Pathology
- Research Papers: Immunology
- Research Papers: Chromosome
- Reviews
- Research Papers
- Clinical Research Papers

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Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model. See Duquette et al.
Table of Contents
Editorial: Immunology
How lung infection leads to gut injury
How lung infection leads to gut injury |
https://doi.org/10.18632/oncotarget.6470 Jian Wang, and Zhigang Tian |
42394-42395 |
PDF | How to cite |
Priority Research Papers
Potent efficacy of metronomic topotecan and pazopanib combination therapy in preclinical models of primary or late stage metastatic triple-negative breast cancer
Potent efficacy of metronomic topotecan and pazopanib combination therapy in preclinical models of primary or late stage metastatic triple-negative breast cancer |
https://doi.org/10.18632/oncotarget.6377 Teresa Di Desidero, Ping Xu, Shan Man, Guido Bocci, and Robert S. Kerbel |
42396-42410 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents
Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents |
https://doi.org/10.18632/oncotarget.6389 Vit Sestak, Jan Stariat, Jolana Cermanova, Eliska Potuckova, Jaroslav Chladek, Jaroslav Roh, Jan Bures, Hana Jansova, Petr Prusa, Martin Sterba, Stanislav Micuda, Tomas Simunek, Danuta S. Kalinowski, Des R. Richardson, and Petra Kovarikova |
42411-42428 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Genomic landscape of liposarcoma
Genomic landscape of liposarcoma |
https://doi.org/10.18632/oncotarget.6464 Deepika Kanojia, Yasunobu Nagata, Manoj Garg, Dhong Hyun Lee, Aiko Sato, Kenichi Yoshida, Yusuke Sato, Masashi Sanada, Anand Mayakonda, Christoph Bartenhagen, Hans-Ulrich Klein, Ngan B. Doan, Jonathan W. Said, S. Mohith, Swetha Gunasekar, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Ola Myklebost, Henry Yang, Martin Dugas, Leonardo A. Meza-Zepeda, Allan W. Silberman, Charles Forscher, Jeffrey W. Tyner, Seishi Ogawa, and H. Phillip Koeffler |
42429-42444 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model
Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model |
https://doi.org/10.18632/oncotarget.6442 Mark Duquette, Peter M. Sadow, Amjad Husain, Jennifer N. Sims, Zeus A. Antonello, Andrew H. Fischer, Chen Song, Elena Castellanos-Rizaldos, G. Mike Makrigiorgos, Junichi Kurebayashi, Vania Nose, Paul Van Hummelen, Roderick T. Bronson, Michelle Vinco, Thomas J. Giordano, Dora Dias-Santagata, Pier Paolo Pandolfi, and Carmelo Nucera |
42445-42467 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk
Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk |
https://doi.org/10.18632/oncotarget.6468 Kyle M. Walsh, Veryan Codd, Terri Rice, Christopher P. Nelson, Ivan V. Smirnov, Lucie S. McCoy, Helen M. Hansen, Edward Elhauge, Juhi Ojha, Stephen S. Francis, Nils R. Madsen, Paige M. Bracci, Alexander R. Pico, Annette M. Molinaro, Tarik Tihan, Mitchel S. Berger, Susan M. Chang, Michael D. Prados, Robert B. Jenkins, Joseph L. Wiemels, ENGAGE Consortium Telomere Group, Nilesh J. Samani, John K. Wiencke, and Margaret R. Wrensch |
42468-42477 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-κB
Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-κB |
https://doi.org/10.18632/oncotarget.6478 Ying Hu, Wenjie Ge, Xingwen Wang, Gopinath Sutendra, Kunming Zhao, Zinaida Dedeić, Elizabeth A. Slee, Caroline Baer, and Xin Lu |
42478-42490 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Research Papers: Pathology
Aberrant modulation of the BRCA1 and G1/S cell cycle pathways in alcoholic hepatitis patients with Mallory Denk Bodies revealed by RNA sequencing
Aberrant modulation of the BRCA1 and G1/S cell cycle pathways in alcoholic hepatitis patients with Mallory Denk Bodies revealed by RNA sequencing |
https://doi.org/10.18632/oncotarget.6382 Hui Liu, Ming Gong, Barbara A. French, Guanghong Liao, Jun Li, Brittany Tillman, and Samuel W. French |
42491-42503 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Genome-wide haplotype association study identify TNFRSF1A, CASP7, LRP1B, CDH1 and TG genes associated with Alzheimer’s disease in Caribbean Hispanic individuals
Genome-wide haplotype association study identify TNFRSF1A, CASP7, LRP1B, CDH1 and TG genes associated with Alzheimer’s disease in Caribbean Hispanic individuals |
https://doi.org/10.18632/oncotarget.6391 Zhenwei Shang, Hongchao Lv, Mingming Zhang, Lian Duan, Situo Wang, Jin Li, Guiyou Liu, Zhang Ruijie, and Yongshuai Jiang |
42504-42514 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Antihypertensive treatments in adult autosomal dominant polycystic kidney disease: network meta-analysis of the randomized controlled trials
Antihypertensive treatments in adult autosomal dominant polycystic kidney disease: network meta-analysis of the randomized controlled trials |
https://doi.org/10.18632/oncotarget.6452 Cheng Xue, Chenchen Zhou, Bing Dai, Shengqiang Yu, Chenggang Xu, Zhiguo Mao, Chaoyang Ye, Dongping Chen, Xuezhi Zhao, Jun Wu, Wansheng Chen, and Changlin Mei |
42515-42529 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Oleoylethanolamide, an endogenous PPAR-α ligand, attenuates liver fibrosis targeting hepatic stellate cells
Oleoylethanolamide, an endogenous PPAR-α ligand, attenuates liver fibrosis targeting hepatic stellate cells |
https://doi.org/10.18632/oncotarget.6466 Ling Chen, Long Li, Junde Chen, Lei Li, Zihan Zheng, Jie Ren, and Yan Qiu |
42530-42540 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Research Papers: Immunology
Saikosaponin A inhibits influenza A virus replication and lung immunopathology
Saikosaponin A inhibits influenza A virus replication and lung immunopathology |
https://doi.org/10.18632/oncotarget.6448 Jianxin Chen, Mubing Duan, Yaqin Zhao, Fangfang Ling, Kun Xiao, Qian Li, Bin Li, Chunni Lu, Wenbao Qi, Zhenling Zeng, Ming Liao, Yahong Liu, and Weisan Chen |
42541-42556 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Plasma microRNA expression profiles in Chinese patients with rheumatoid arthritis
Plasma microRNA expression profiles in Chinese patients with rheumatoid arthritis |
https://doi.org/10.18632/oncotarget.6449 Wenhong Wang, Yingying Zhang, Bo Zhu, Tanghai Duan, Qiugui Xu, Rui Wang, Liwei Lu, and Zhijun Jiao |
42557-42568 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
NK cell expression of natural cytotoxicity receptors may determine relapse risk in older AML patients undergoing immunotherapy for remission maintenance
NK cell expression of natural cytotoxicity receptors may determine relapse risk in older AML patients undergoing immunotherapy for remission maintenance |
https://doi.org/10.18632/oncotarget.5559 Anna Martner, Anna Rydström, Rebecca E. Riise, Johan Aurelius, Mats Brune, Robin Foà, Kristoffer Hellstrand, and Fredrik B. Thorén |
42569-42574 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Press Release |
Research Papers: Chromosome
Hormone stimulation of androgen receptor mediates dynamic changes in DNA methylation patterns at regulatory elements
Hormone stimulation of androgen receptor mediates dynamic changes in DNA methylation patterns at regulatory elements |
https://doi.org/10.18632/oncotarget.6471 Vineet K. Dhiman, Kristopher Attwood, Moray J. Campbell, and Dominic J. Smiraglia |
42575-42589 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Reviews
The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implications
The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implications |
https://doi.org/10.18632/oncotarget.6052 Youzhou Sang, Fan Yan, and Xiubao Ren |
42590-42602 |
Abstract | PDF | HTML | How to cite |
The double face of Morgana in tumorigenesis
The double face of Morgana in tumorigenesis |
https://doi.org/10.18632/oncotarget.6058 Mara Brancaccio, Stefania Rocca, Laura Seclì, Elena Busso, and Federica Fusella |
42603-42612 |
Abstract | PDF | HTML | How to cite |
Non-coding RNAs in cardiac regeneration
Non-coding RNAs in cardiac regeneration |
https://doi.org/10.18632/oncotarget.6073 Lichan Tao, Yihua Bei, Yanli Zhou, Junjie Xiao, and Xinli Li |
42613-42622 |
Abstract | PDF | HTML | How to cite |
Research Papers
Diagnosis of skin cancer by correlation and complexity analyses of damaged DNA
Diagnosis of skin cancer by correlation and complexity analyses of damaged DNA |
https://doi.org/10.18632/oncotarget.6003 Hamidreza Namazi, Vladimir V. Kulish, Fatemeh Delaviz, and Ali Delaviz |
42623-42631 |
Abstract | PDF | HTML | How to cite |
Acyl-CoA synthetase-4, a new regulator of mTOR and a potential therapeutic target for enhanced estrogen receptor function in receptor-positive and -negative breast cancer
Acyl-CoA synthetase-4, a new regulator of mTOR and a potential therapeutic target for enhanced estrogen receptor function in receptor-positive and -negative breast cancer |
https://doi.org/10.18632/oncotarget.5822 Ulises D. Orlando, Ana F. Castillo, Melina A. Dattilo, Angela R. Solano, Paula M. Maloberti, and Ernesto J. Podesta |
42632-42650 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
EMT-induced metabolite signature identifies poor clinical outcome
EMT-induced metabolite signature identifies poor clinical outcome |
https://doi.org/10.18632/oncotarget.4765 Salil Kumar Bhowmik, Esmeralda Ramirez-Peña, James Michael Arnold, Vasanta Putluri, Nathalie Sphyris, George Michailidis, Nagireddy Putluri, Stefan Ambs, Arun Sreekumar, and Sendurai A. Mani |
42651-42660 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Genetic variant of PRKAA1 and gastric cancer risk in an eastern Chinese population
Genetic variant of PRKAA1 and gastric cancer risk in an eastern Chinese population |
https://doi.org/10.18632/oncotarget.6124 Li-Xin Qiu, Jing He, Lei Cheng, Fei Zhou, Meng-Yun Wang, Meng-Hong Sun, Xiao-Yan Zhou, Jin Li, Wei-Jian Guo, Ya-Nong Wang, Ya-Jun Yang, Jiu-Cun Wang, Li Jin, Xiao-Dong Zhu, and Qing-Yi Wei |
42661-42666 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells
The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells |
https://doi.org/10.18632/oncotarget.5626 Donatella Malanga, Carmela De Marco, Ilaria Guerriero, Fabiana Colelli, Nicola Rinaldo, Marianna Scrima, Teresa Mirante, Claudia De Vitis, Pietro Zoppoli, Michele Ceccarelli, Miriam Riccardi, Maria Ravo, Alessandro Weisz, Antonella Federico, Renato Franco, Gaetano Rocco, Rita Mancini, Antonia Rizzuto, Elio Gulletta, Gennaro Ciliberto, and Giuseppe Viglietto |
42667-42686 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
ILs-3, 6 and 11 increase, but ILs-10 and 24 decrease stemness of human prostate cancer cells in vitro
ILs-3, 6 and 11 increase, but ILs-10 and 24 decrease stemness of human prostate cancer cells in vitro |
https://doi.org/10.18632/oncotarget.5883 Dan-Dan Yu, Ya-Li Zhong, Xiao-Ran Li, Ya-Qing Li, Xiao-Li Li, Jing Cao, Hui-Jie Fan, Yuan Yuan, Zhen-Yu Ji, Bao-Ping Qiao, Jian-Guo Wen, Ming-Zhi Zhang, Gunnar Kvalheim, Jahn M. Nesland, and Zhen-He Suo |
42687-42703 |
Abstract | PDF | HTML | How to cite |
Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis
Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis |
https://doi.org/10.18632/oncotarget.5678 Xiangjian Luo, Lifang Yang, Lanbo Xiao, Xiaofeng Xia, Xin Dong, Juanfang Zhong, Ying Liu, Namei Li, Ling Chen, Hongde Li, Wei Li, Wenbin Liu, Xinfang Yu, Hanyong Chen, Min Tang, Xinxian Weng, Wei Yi, Ann Bode, Zigang Dong, Jikai Liu, and Ya Cao |
42704-42716 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor
NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor |
https://doi.org/10.18632/oncotarget.3956 Elena Galvani, Jing Sun, Leticia G. Leon, Rocco Sciarrillo, Ravi S. Narayan, Robert Tjin Tham Sjin, Kwangho Lee, Kadoaki Ohashi, Daniëlle A.M. Heideman, Roberta R. Alfieri, Guus J. Heynen, René Bernards, Egbert F. Smit, William Pao, Godefridus J. Peters, and Elisa Giovannetti |
42717-42732 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Identification of a novel platelet antagonist that binds to CLEC-2 and suppresses podoplanin-induced platelet aggregation and cancer metastasis
Identification of a novel platelet antagonist that binds to CLEC-2 and suppresses podoplanin-induced platelet aggregation and cancer metastasis |
https://doi.org/10.18632/oncotarget.5811 Yao-Wen Chang, Pei-Wen Hsieh, Yu-Tsui Chang, Meng-Hong Lu, Tur-Fu Huang, Kowit-Yu Chong, Hsiang-Ruei Liao, Ju-Chien Cheng, and Ching-Ping Tseng |
42733-42748 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Colon cancer cell invasion is promoted by protein kinase CK2 through increase of endothelin-converting enzyme-1c protein stability
Colon cancer cell invasion is promoted by protein kinase CK2 through increase of endothelin-converting enzyme-1c protein stability |
https://doi.org/10.18632/oncotarget.5722 Ignacio Niechi, Eduardo Silva, Pablo Cabello, Hernan Huerta, Valentina Carrasco, Paulina Villar, Luis Rodrigo Cataldo, Katherine Marcelain, Ricardo Armisen, Manuel Varas-Godoy, Cristina Fernandez, and Julio C. Tapia |
42749-42760 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
MiR-542-5p is a negative prognostic factor and promotes osteosarcoma tumorigenesis by targeting HUWE1
MiR-542-5p is a negative prognostic factor and promotes osteosarcoma tumorigenesis by targeting HUWE1 |
https://doi.org/10.18632/oncotarget.6199 Dong-dong Cheng, Tao Yu, Tu Hu, Ming Yao, Cun-yi Fan, and Qing-cheng Yang |
42761-42772 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Predictive significance of DNA damage and repair biomarkers in triple-negative breast cancer patients treated with neoadjuvant chemotherapy: An exploratory analysis
Predictive significance of DNA damage and repair biomarkers in triple-negative breast cancer patients treated with neoadjuvant chemotherapy: An exploratory analysis |
https://doi.org/10.18632/oncotarget.6001 Patrizia Vici, Anna Di Benedetto, Cristiana Ercolani, Laura Pizzuti, Luigi Di Lauro, Domenico Sergi, Francesca Sperati, Irene Terrenato, Rosanna Dattilo, Claudio Botti, Alessandra Fabi, Maria Teresa Ramieri, Lucia Mentuccia, Camilla Marinelli, Laura Iezzi, Teresa Gamucci, Clara Natoli, Ilio Vitale, Maddalena Barba, Marcella Mottolese, Ruggero De Maria, and Marcello Maugeri-Saccà |
42773-42780 |
Abstract | PDF | HTML | How to cite |
A functional variant in miR-155 regulation region contributes to lung cancer risk and survival
A functional variant in miR-155 regulation region contributes to lung cancer risk and survival |
https://doi.org/10.18632/oncotarget.5840 Kaipeng Xie, Hongxia Ma, Cheng Liang, Cheng Wang, Na Qin, Wei Shen, Yayun Gu, Caiwang Yan, Kai Zhang, Ningbin Dai, Meng Zhu, Shuangshuang Wu, Hui Wang, Juncheng Dai, Guangfu Jin, Hongbing Shen, and Zhibin Hu |
42781-42792 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia
Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia |
https://doi.org/10.18632/oncotarget.6000 Setareh Safavi, Linda Olsson, Andrea Biloglav, Srinivas Veerla, Molly Blendberg, Johnbosco Tayebwa, Mikael Behrendtz, Anders Castor, Markus Hansson, Bertil Johansson, and Kajsa Paulsson |
42793-42802 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Iron deficient erythropoiesis might play key role in development of anemia in cancer patients
Iron deficient erythropoiesis might play key role in development of anemia in cancer patients |
https://doi.org/10.18632/oncotarget.5658 Silvia Park, Chul Won Jung, Kihyun Kim, Seok Jin Kim, Won Seog Kim, and Jun Ho Jang |
42803-42812 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
LINC00152 promotes proliferation in hepatocellular carcinoma by targeting EpCAM via the mTOR signaling pathway
LINC00152 promotes proliferation in hepatocellular carcinoma by targeting EpCAM via the mTOR signaling pathway |
https://doi.org/10.18632/oncotarget.5970 Jie Ji, Junwei Tang, Lei Deng, Yu Xie, Runqiu Jiang, Guoqiang Li, and Beicheng Sun |
42813-42824 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Bone marrow-derived mesenchymal stem cell-secreted IL-8 promotes the angiogenesis and growth of colorectal cancer
Bone marrow-derived mesenchymal stem cell-secreted IL-8 promotes the angiogenesis and growth of colorectal cancer |
https://doi.org/10.18632/oncotarget.5739 Jiancheng Wang, Yingnan Wang, Shaochuan Wang, Jianye Cai, Jiangqiang Shi, Xin Sui, Yong Cao, Weijun Huang, Xiaoyong Chen, Zijie Cai, Hongyu Li, Adham Sameer A. Bardeesi, Bin Zhang, Muyun Liu, Wu Song, Maosheng Wang, and Andy Peng Xiang |
42825-42837 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
HOXB9 induction of mesenchymal-to-epithelial transition in gastric carcinoma is negatively regulated by its hexapeptide motif
HOXB9 induction of mesenchymal-to-epithelial transition in gastric carcinoma is negatively regulated by its hexapeptide motif |
https://doi.org/10.18632/oncotarget.5814 Qing Chang, Li Zhang, Changyu He, Baogui Zhang, Jun Zhang, Bingya Liu, Naiyan Zeng, and Zhenggang Zhu |
42838-42853 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
HRD1 suppresses the growth and metastasis of breast cancer cells by promoting IGF-1R degradation
HRD1 suppresses the growth and metastasis of breast cancer cells by promoting IGF-1R degradation |
https://doi.org/10.18632/oncotarget.5733 Yue-Mei Xu, Hong-Jiang Wang, Fang Chen, Wan-Hua Guo, Yan-Yang Wang, Hang-Yu Li, Jin-Hai Tang, Ying Ding, Ya-Chen Shen, Min Li, Wen-Ying Xuan, Lin-Hui Liu, Jia Wang, Xue-Rong Wang, Ze-Jun Gao, Xiu-Bin Liang, and Dong-Ming Su |
42854-42867 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
HER3 over-expression and overall survival in gastrointestinal cancers
HER3 over-expression and overall survival in gastrointestinal cancers |
https://doi.org/10.18632/oncotarget.5998 Yadong Wang, Haiyan Yang, and Guangcai Duan |
42868-42878 |
Abstract | PDF | HTML | How to cite |
Enhancement of NAD+-dependent SIRT1 deacetylase activity by methylselenocysteine resets the circadian clock in carcinogen-treated mammary epithelial cells
Enhancement of NAD+-dependent SIRT1 deacetylase activity by methylselenocysteine resets the circadian clock in carcinogen-treated mammary epithelial cells |
https://doi.org/10.18632/oncotarget.6002 Mingzhu Fang, Wei-Ren Guo, Yongil Park, Hwan-Goo Kang, and Helmut Zarbl |
42879-42891 |
Abstract | PDF | HTML | How to cite |
Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis
Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis |
https://doi.org/10.18632/oncotarget.5740 Rossella Tricarico, Salvatore Cortellino, Antonio Riccio, Shantie Jagmohan-Changur, Heleen van der Klift, Juul Wijnen, David Turner, Andrea Ventura, Valentina Rovella, Antonio Percesepe, Emanuela Lucci-Cordisco, Paolo Radice, Lucio Bertario, Monica Pedroni, Maurizio Ponz de Leon, Pietro Mancuso, Karthik Devarajan, Kathy Q. Cai, Andres J.P. Klein-Szanto, Giovanni Neri, Pål Møller, Alessandra Viel, Maurizio Genuardi, Riccardo Fodde, and Alfonso Bellacosa |
42892-42904 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Growth-stimulatory activity of TIMP-2 is mediated through c-Src activation followed by activation of FAK, PI3-kinase/AKT, and ERK1/2 independent of MMP inhibition in lung adenocarcinoma cells
Growth-stimulatory activity of TIMP-2 is mediated through c-Src activation followed by activation of FAK, PI3-kinase/AKT, and ERK1/2 independent of MMP inhibition in lung adenocarcinoma cells |
https://doi.org/10.18632/oncotarget.5466 Han Ie Kim, Hyun Sung Lee, Tae Hyun Kim, Ju-Seog Lee, Seung-Taek Lee, and Seo-Jin Lee |
42905-42922 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer
Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer |
https://doi.org/10.18632/oncotarget.5976 Wei-Ching Chen, Yung-Sheng Chang, Hui-Ping Hsu, Meng-Chi Yen, Hau-Lun Huang, Chien-Yu Cho, Chih-Yang Wang, Tzu-Yang Weng, Po-Ting Lai, Ching-Shih Chen, Yih-Jyh Lin, and Ming-Derg Lai |
42923-42937 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Phenotypic profile of expanded NK cells in chronic lymphoproliferative disorders: a surrogate marker for NK-cell clonality
Phenotypic profile of expanded NK cells in chronic lymphoproliferative disorders: a surrogate marker for NK-cell clonality |
https://doi.org/10.18632/oncotarget.5480 Paloma Bárcena, María Jara-Acevedo, María Dolores Tabernero, Antonio López, María Luz Sánchez, Andrés C. García-Montero, Noemí Muñoz-García, María Belén Vidriales, Artur Paiva, Quentin Lecrevisse, Margarida Lima, Anton W. Langerak, Sebastian Böttcher, Jacques J.M. van Dongen, Alberto Orfao, and Julia Almeida |
42938-42951 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Hepatitis B virus (HBV) receptors: Deficiency in tumor results in scant HBV infection and overexpression in peritumor leads to higher recurrence risk
Hepatitis B virus (HBV) receptors: Deficiency in tumor results in scant HBV infection and overexpression in peritumor leads to higher recurrence risk |
https://doi.org/10.18632/oncotarget.5518 Ying-Ying Jing, Wen-Ting Liu, Shi-Wei Guo, Fei Ye, Qing-Min Fan, Guo-Feng Yu, Dan-Dan Yu, Lu Gao, Kai Sun, Zhi-Peng Han, Rong Li, Yang Yang, Qiu-Dong Zhao, Meng-Chao Wu, Hong-Yang Wang, and Li-Xin Wei |
42952-42962 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Chemopreventive effect of resveratrol and apocynin on pancreatic carcinogenesis via modulation of nuclear phosphorylated GSK3β and ERK1/2
Chemopreventive effect of resveratrol and apocynin on pancreatic carcinogenesis via modulation of nuclear phosphorylated GSK3β and ERK1/2 |
https://doi.org/10.18632/oncotarget.5981 Akihisa Kato, Aya Naiki-Ito, Takahiro Nakazawa, Kazuki Hayashi, Itaru Naitoh, Katsuyuki Miyabe, Shuya Shimizu, Hiromu Kondo, Yuji Nishi, Michihiro Yoshida, Shuichiro Umemura, Yasuki Hori, Toshio Mori, Masahiro Tsutsumi, Toshiya Kuno, Shugo Suzuki, Hiroyuki Kato, Hirotaka Ohara, Takashi Joh, and Satoru Takahashi |
42963-42975 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Cancer metastasis and EGFR signaling is suppressed by amiodarone-induced versican V2
Cancer metastasis and EGFR signaling is suppressed by amiodarone-induced versican V2 |
https://doi.org/10.18632/oncotarget.5621 Hung-Chieh Lee, Mai-Yan Su, Hao-Chan Lo, Chin-Chieh Wu, Jia-Rung Hu, Dao-Ming Lo, Tsu-Yi Chao, Huai-Jen Tsai, and Ming-Shen Dai |
42976-42987 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Statin use and breast cancer survival and risk: a systematic review and meta-analysis
Statin use and breast cancer survival and risk: a systematic review and meta-analysis |
https://doi.org/10.18632/oncotarget.5557 Qi-Jun Wu, Chao Tu, Yuan-Yuan Li, Jingjing Zhu, Ke-Qing Qian, Wen-Jing Li, and Lang Wu |
42988-43004 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
TGF-β blockade depletes T regulatory cells from metastatic pancreatic tumors in a vaccine dependent manner
TGF-β blockade depletes T regulatory cells from metastatic pancreatic tumors in a vaccine dependent manner |
https://doi.org/10.18632/oncotarget.5656 Kevin C. Soares, Agnieszka A. Rucki, Victoria Kim, Kelly Foley, Sara Solt, Christopher L. Wolfgang, Elizabeth M. Jaffee, and Lei Zheng |
43005-43015 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis
Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis |
https://doi.org/10.18632/oncotarget.5513 Letícia F. Leal, Ana Carolina Bueno, Débora C. Gomes, Rafael Abduch, Margaret de Castro, and Sonir R. Antonini |
43016-43032 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
miR-150 inhibits terminal erythroid proliferation and differentiation
miR-150 inhibits terminal erythroid proliferation and differentiation |
https://doi.org/10.18632/oncotarget.5824 Zhiwei Sun, Ye Wang, Xu Han, Xielan Zhao, Yuanliang Peng, Yusheng Li, Minyuan Peng, Jianhui Song, Kunlu Wu, Shumin Sun, Weihua Zhou, Biwei Qi, Chufan Zhou, Huiyong Chen, Xiuli An, and Jing Liu |
43033-43047 |
Abstract | PDF | HTML | How to cite |
Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia
Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia |
https://doi.org/10.18632/oncotarget.5528 Jizhong Liu, Ashish Masurekar, Suzanne Johnson, Sohini Chakraborty, John Griffiths, Duncan Smith, Seema Alexander, Clare Dempsey, Catriona Parker, Stephanie Harrison, Yaoyong Li, Crispin Miller, Yujun Di, Zhumur Ghosh, Shekhar Krishnan, and Vaskar Saha |
43048-43064 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Mitochondrial oncobioenergetic index: A potential biomarker to predict progression from indolent to aggressive prostate cancer
Mitochondrial oncobioenergetic index: A potential biomarker to predict progression from indolent to aggressive prostate cancer |
https://doi.org/10.18632/oncotarget.5487 Praveen K. Vayalil, and Aimee Landar |
43065-43080 |
Abstract | PDF | HTML | How to cite |
Infiltrating neutrophils increase bladder cancer cell invasion via modulation of androgen receptor (AR)/MMP13 signals
Infiltrating neutrophils increase bladder cancer cell invasion via modulation of androgen receptor (AR)/MMP13 signals |
https://doi.org/10.18632/oncotarget.5638 ChangYi Lin, WanYing Lin, Shuyuan Yeh, Lei Li, and Chawnshang Chang |
43081-43089 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Clinical Research Papers
Aspartate aminotransferase-lymphocyte ratio index and systemic immune-inflammation index predict overall survival in HBV-related hepatocellular carcinoma patients after transcatheter arterial chemoembolization
Aspartate aminotransferase-lymphocyte ratio index and systemic immune-inflammation index predict overall survival in HBV-related hepatocellular carcinoma patients after transcatheter arterial chemoembolization |
https://doi.org/10.18632/oncotarget.5719 Zongguo Yang, Jianliang Zhang, Yunfei Lu, Qingnian Xu, Bozong Tang, Qiang Wang, Wensi Zhang, Shishi Chen, Lingqing Lu, and Xiaorong Chen |
43090-43098 |
Abstract | PDF | HTML | How to cite |
Dietary fat and fatty acid intake and epithelial ovarian cancer risk: evidence from epidemiological studies
Dietary fat and fatty acid intake and epithelial ovarian cancer risk: evidence from epidemiological studies |
https://doi.org/10.18632/oncotarget.5525 Rui Hou, Qi-Jun Wu, Ting-Ting Gong, and Luo Jiang |
43099-43119 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Clinical analysis of intraoperative radiotherapy during breast-conserving surgery of early breast cancer in the Chinese Han population
Clinical analysis of intraoperative radiotherapy during breast-conserving surgery of early breast cancer in the Chinese Han population |
https://doi.org/10.18632/oncotarget.5716 Xin Wang, Jiaqi Liu, Wenyan Wang, Qinfu Feng, and Xiang Wang |
43120-43126 |
Abstract | PDF | HTML | How to cite |
Phase 1b study of lenvatinib (E7080) in combination with temozolomide for treatment of advanced melanoma
Phase 1b study of lenvatinib (E7080) in combination with temozolomide for treatment of advanced melanoma |
https://doi.org/10.18632/oncotarget.5756 David S. Hong, Razelle Kurzrock, Gerald S. Falchook, Corina Andresen, Jennifer Kwak, Min Ren, Lucy Xu, Goldy C. George, Kevin B. Kim, Ly M. Nguyen, James P. O’Brien, and John Nemunaitis |
43127-43134 |
Abstract | PDF | HTML | Supplementary Information | How to cite |
Chemotherapy of metastatic triple negative breast cancer: Experience of using platinum-based chemotherapy
Chemotherapy of metastatic triple negative breast cancer: Experience of using platinum-based chemotherapy |
https://doi.org/10.18632/oncotarget.5654 Jian Zhang, Minhao Fan, Jie Xie, Zhonghua Wang, Biyun Wang, Sheng Zhang, Leiping Wang, Jun Cao, Zhonghua Tao, Ting Li, and Xichun Hu |
43135-43143 |
Abstract | PDF | HTML | How to cite |
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