Cell autonomous Vegf-C/Vegfr3 signaling in adult neural stem cells

ASM in Alzheimer’s disease

Risk-reducing surgery in BRCA 1/2 mutation carries: a point of view

Sequencing rare T-cell populations

Heregulin, a new regulator of telomere length in human cells

Changes in autophagy, proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells

Mitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats

Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity

Influence of companion diagnostics on efficacy and safety of targeted anti-cancer drugs: systematic review and meta-analyses

Differentiation and transdifferentiation potentials of cancer stem cells

Epithelial neoplasia coincides with exacerbated injury and fibrotic response in the lungs of Gprc5a-knockout mice following silica exposure

Silibinin enhances the repair of ultraviolet B-induced DNA damage by activating p53-dependent nucleotide excision repair mechanism in human dermal fibroblasts

Molecular pathological epidemiology of colorectal cancer in Chinese patients with KRAS and BRAF mutations

Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer

Mutant AKT1-E17K is oncogenic in lung epithelial cells

IDH1 mutation detection by droplet digital PCR in glioma

MiR-652 inhibits acidic microenvironment-induced epithelial-mesenchymal transition of pancreatic cancer cells by targeting ZEB1

Tumor necrosis is an important hallmark of aggressive endometrial cancer and associates with hypoxia, angiogenesis and inflammation responses

CGK733-induced LC3 II formation is positively associated with the expression of cyclin-dependent kinase inhibitor p21^Waf1/Cip1 through modulation of the AMPK and PERK/CHOP signaling pathways

mTOR inhibitors sensitize thyroid cancer cells to cytotoxic effect of vemurafenib

Suppressing NRIP1 inhibits growth of breast cancer cells in vitro and in vivo

Practice of traditional Chinese medicine for psycho-behavioral intervention improves quality of life in cancer patients: A systematic review and meta-analysis

Overexpression of CHI3L1 is associated with chemoresistance and poor outcome of epithelial ovarian carcinoma

Hsa-miR-139-5p inhibits proliferation and causes apoptosis associated with down-regulation of c-Met

LncRNA ontology: inferring lncRNA functions based on chromatin states and expression patterns

Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer – a crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation

Combined inhibition of heat shock proteins 90 and 70 leads to simultaneous degradation of the oncogenic signaling proteins involved in muscle invasive bladder cancer

Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells

Rs488087 single nucleotide polymorphism as predictive risk factor for pancreatic cancers

Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide

INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas

Frizzled-7 promoter is highly active in tumors and promoter-driven Shiga-like toxin I inhibits hepatocellular carcinoma growth

Key contribution of eIF4H-mediated translational control in tumor promotion

Prostaglandins induce early growth response 1 transcription factor mediated microsomal prostaglandin E₂ synthase up-regulation for colorectal cancer progression

Impact of wall shear stress and ligand avidity on binding of anti-CD146-coated nanoparticles to murine tumor endothelium under flow

Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV Vif

The 5′-untranslated region of p16^INK4a melanoma tumor suppressor acts as a cellular IRES, controlling mRNA translation under hypoxia through YBX1 binding

Polymorphisms involving gain or loss of CpG sites are significantly enriched in trait-associated SNPs

A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype

PIK3CA mutation detection in metastatic biliary cancer using cell-free DNA

Specific inhibition by synthetic analogs of pyruvate reveals that the pyruvate dehydrogenase reaction is essential for metabolism and viability of glioblastoma cells

LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma

The herbal compound Songyou Yin (SYY) inhibits hepatocellular carcinoma growth and improves survival in models of chronic fibrosis via paracrine inhibition of activated hepatic stellate cells

Aberrant high expression of immunoglobulin G in epithelial stem/progenitor-like cells contributes to tumor initiation and metastasis

Expression of young HERV-H loci in the course of colorectal carcinoma and correlation with molecular subtypes

Aberrant expression of homeobox gene SIX1 in Hodgkin lymphoma

Comparative effectiveness study of breast-conserving surgery and mastectomy in the general population: A NCDB analysis

The PIM inhibitor AZD1208 synergizes with ruxolitinib to induce apoptosis of ruxolitinib sensitive and resistant JAK2-V617F-driven cells and inhibit colony formation of primary MPN cells

Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer

Potential involvement of miR-375 in the premalignant progression of oral squamous cell carcinoma mediated via transcription factor KLF5

Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq

Ligand-based chemoinformatic discovery of a novel small molecule inhibitor targeting CDC25 dual specificity phosphatases and displaying in vitro efficacy against melanoma cells

Peritumoral Cbl is a strong independent prognostic marker after curative resection of hepatocellular carcinoma

Genes with stable DNA methylation levels show higher evolutionary conservation than genes with fluctuant DNA methylation levels

ERβ regulation of NF-κB activation in prostate cancer is mediated by HIF-1

Targeting stemness is an effective strategy to control EML4-ALK+ non-small cell lung cancer cells

Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines

Identification of CD146 as a marker enriched for tumor-propagating capacity reveals targetable pathways in primary human sarcoma

Changes in microRNA (miRNA) expression during pancreatic cancer development and progression in a genetically engineered Kras^G12D;Pdx1-Cre mouse (KC) model

Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion

Genome-wide association study identifies two new susceptibility loci for colorectal cancer at 5q23.3 and 17q12 in Han Chinese

Prospective blinded study of somatic mutation detection in cell-free DNA utilizing a targeted 54-gene next generation sequencing panel in metastatic solid tumor patients

Overexpression of caldesmon is associated with tumor progression in patients with primary non-muscle-invasive bladder cancer