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About The Cover
Representative high and low staining immunofluorescent microscopy images for each marker. LC = loading control (β-actin), DAPI = nuclear stain, CK = cytokeratin (epithelial tumor stain). See Beck et al.
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Table of Contents
Editorial
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| Mastl/PP2A regulate Cdk1 in ooycte maturation |
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https://doi.org/10.18632/oncotarget.4916
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| 18734-18735 |
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| FPRs: linking innate immune system and fibrosis |
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https://doi.org/10.18632/oncotarget.4915
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| 18736-18737 |
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| Scribble dictates orderly stem cell fate |
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https://doi.org/10.18632/oncotarget.4923
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| 18738-18739 |
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| Fragments and hot spots in drug discovery |
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https://doi.org/10.18632/oncotarget.4968
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| 18740-18741 |
Editorial: Chromosome
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| A bacterial toxin that cleaves Ras oncoprotein |
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https://doi.org/10.18632/oncotarget.5113
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| 18742-18743 |
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| Antimicrobial peptides targeting bacterial ribosome |
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https://doi.org/10.18632/oncotarget.5114
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| 18744-18745 |
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| Unexpected insights for antiEGFR cancer therapy |
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https://doi.org/10.18632/oncotarget.5115
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| 18746-18747 |
Reviews
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| Targeting cancer by binding iron: Dissecting cellular signaling pathways |
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https://doi.org/10.18632/oncotarget.4349
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| 18748-18779 |
Priority Research Papers
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| MYCrepressed long noncoding RNAs antagonize MYCinduced cell proliferation and cell cycle progression |
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https://doi.org/10.18632/oncotarget.3909
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| 18780-18789 |
Research Papers: Gerotarget (Focus on Aging)
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| Bmk1 regulates lifespan in Caenorhabditis elegans by activating hsp16 |
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https://doi.org/10.18632/oncotarget.4618
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| 18790-18799 |
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| Differential modulation of AMPK/PPARα/UCP2 axis in relation to hypertension and aging in the brain kidneys and heart of two closely related spontaneously hypertensive rat strains |
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https://doi.org/10.18632/oncotarget.4033
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| 18800-18818 |
Research Papers: Pathology
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| Evidence for the involvement of sphingosine1phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow |
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https://doi.org/10.18632/oncotarget.4710
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| 18819-18828 |
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| Inhibition of microRNA497 ameliorates anoxia/reoxygenation injury in cardiomyocytes by suppressing cell apoptosis and enhancing autophagy |
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https://doi.org/10.18632/oncotarget.4774
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| 18829-18844 |
Research Papers: Chromosome
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| Integration of microarray analysis into the clinical diagnosis of hematological malignancies: How much can we improve cytogenetic testing |
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https://doi.org/10.18632/oncotarget.4586
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| 18845-18862 |
Research Papers
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| PhosphoT356RB1 predicts survival in HPVnegative squamous cell carcinoma of the head and neck |
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https://doi.org/10.18632/oncotarget.4321
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| 18863-18874 |
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| The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin |
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https://doi.org/10.18632/oncotarget.4303
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| 18875-18890 |
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| Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration |
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https://doi.org/10.18632/oncotarget.3783
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| 18891-18904 |
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| Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma |
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https://doi.org/10.18632/oncotarget.4305
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| 18905-18920 |
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| Small molecule inhibitor screen identifies synergistic activity of the bromodomain inhibitor CPI203 and bortezomib in drug resistant myeloma |
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https://doi.org/10.18632/oncotarget.4214
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| 18921-18932 |
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| microRNA4717 differentially interacts with its polymorphic target in the PD1 3’ untranslated region: A mechanism for regulating PD1 expression and function in HBVassociated liver diseases |
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https://doi.org/10.18632/oncotarget.3662
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| 18933-18944 |
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| Impact of systemic targeted agents on the clinical outcomes of patients with brain metastases |
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https://doi.org/10.18632/oncotarget.4153
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| 18945-18955 |
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| Targeting IRAK1 in Tcell acute lymphoblastic leukemia |
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https://doi.org/10.18632/oncotarget.4150
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| 18956-18965 |
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| Role and prognostic significance of the epithelialmesenchymal transition factor ZEB2 in ovarian cancer |
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https://doi.org/10.18632/oncotarget.3943
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| 18966-18979 |
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| MicroRNA106b inhibits osteoclastogenesis and osteolysis by targeting RANKL in giant cell tumor of bone |
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https://doi.org/10.18632/oncotarget.4223
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| 18980-18996 |
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| The predictive value of ERCC1 and p53 for the effect of panobinostat and cisplatin combination treatment in NSCLC |
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https://doi.org/10.18632/oncotarget.3620
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| 18997-19005 |
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| miR17 regulates melanoma cell motility by inhibiting the translation of ETV1 |
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https://doi.org/10.18632/oncotarget.4147
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| 19006-19016 |
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| SNP interactions of Helicobacter pylorirelated host genes PGC PTPN11 IL1B and TLR4 in susceptibility to gastric carcinogenesis |
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https://doi.org/10.18632/oncotarget.4231
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| 19017-19026 |
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| Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity |
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https://doi.org/10.18632/oncotarget.3699
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| 19027-19042 |
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| miR1238 inhibits cell proliferation by targeting LHX2 in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.4232
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| 19043-19054 |
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| Gα12 overexpressed in hepatocellular carcinoma reduces microRNA122 expression via HNF4α inactivation which causes cMet induction |
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https://doi.org/10.18632/oncotarget.3957
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| 19055-19069 |
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| Identification and characterization of the gene expression profiles for protein coding and noncoding RNAs of pancreatic ductal adenocarcinomas |
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https://doi.org/10.18632/oncotarget.4233
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| 19070-19086 |
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| A novel HMGA1CCNE2YAP axis regulates breast cancer aggressiveness |
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https://doi.org/10.18632/oncotarget.4236
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| 19087-19101 |
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| The SIRT1/TP53 axis is activated upon Bcell receptor triggering via miR132 upregulation in chronic lymphocytic leukemia cells |
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https://doi.org/10.18632/oncotarget.3905
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| 19102-19117 |
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| MUC16mediated activation of mTOR and cMyc reprograms pancreatic cancer metabolism |
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https://doi.org/10.18632/oncotarget.4078
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| 19118-19131 |
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| Integrated analysis of microRNAs transcription factors and target genes expression discloses a specific molecular architecture of hyperdiploid multiple myeloma |
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https://doi.org/10.18632/oncotarget.4302
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| 19132-19147 |
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| Protein phosphatase PHLPP induces cell apoptosis and exerts anticancer activity by inhibiting Survivin phosphorylation and nuclear export in gallbladder cancer |
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https://doi.org/10.18632/oncotarget.3721
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| 19148-19162 |
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| Continuous representation of tumor microvessel density and detection of angiogenic hotspots in histological wholeslide images |
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https://doi.org/10.18632/oncotarget.4383
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| 19163-19176 |
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| Targeting lactate transport suppresses in vivo breast tumour growth |
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https://doi.org/10.18632/oncotarget.3910
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| 19177-19189 |
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| GPER agonist G1 decreases adrenocortical carcinoma ACC cell growth in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.4241
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| 19190-19203 |
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| Classification and clinical behavior of blastic plasmacytoid dendritic cell neoplasms according to their maturationassociated immunophenotypic profile |
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https://doi.org/10.18632/oncotarget.4146
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| 19204-19216 |
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| Elevated preoperative aspartate aminotransferase to lymphocyte ratio index as an independent prognostic factor for patients with hepatocellular carcinoma after hepatic resection |
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https://doi.org/10.18632/oncotarget.4265
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| 19217-19227 |
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| The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism |
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https://doi.org/10.18632/oncotarget.4653
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| 19228-19245 |
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| Circulating small non coding RNA signature in head and neck squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.4266
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| 19246-19263 |
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| Mucin1 promotes the migration and invasion of hepatocellular carcinoma cells via JNKmediated phosphorylation of Smad2 at the Cterminal and linker regions |
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https://doi.org/10.18632/oncotarget.4267
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| 19264-19278 |
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| Tracking subclonal TP53 mutated tumor cells in human metastatic renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.4220
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| 19279-19289 |
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| Infiltrating neutrophils promote renal cell carcinoma progression via VEGFa/HIF2α and estrogen receptor β signals |
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https://doi.org/10.18632/oncotarget.4478
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| 19290-19304 |
Clinical Research Papers
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| Impact of VEGF VEGFR PDGFR HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy |
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https://doi.org/10.18632/oncotarget.4191
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| 19305-19315 |
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| Predictors of early treatment discontinuation in patients enrolled on Phase I oncology trials |
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https://doi.org/10.18632/oncotarget.2909
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| 19316-19327 |
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| Detection of high mobility group A2 specific mRNA in the plasma of patients affected by epithelial ovarian cancer |
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https://doi.org/10.18632/oncotarget.2896
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| 19328-19335 |
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