|
| Overcoming resistance to BRAF inhibition in BRAFmutated metastatic melanoma |
|
https://doi.org/10.18632/oncotarget.2602
Francesco Spagnolo, Paola Ghiorzo, and Paola Queirolo
|
| 10206-10221 |
|
| Regulation of ERBB3/HER3 signaling in cancer |
|
https://doi.org/10.18632/oncotarget.2655
Kalpana Mujoo, Byung-Kwon Choi, Zhao Huang, Ningyan Zhang, and Zhiqiang An
|
| 10222-10236 |
|
| Preclinical efficacy of sepantronium bromide YM155 in multiple myeloma is conferred by down regulation of Mcl1 |
|
https://doi.org/10.18632/oncotarget.2529
Verena Wagner, Dirk Hose, Anja Seckinger, Ludmila Weiz, Tobias Meißner, Thiery Rème, Iris Breitkreutz, Klaus Podar, Anthony D. Ho, Hartmut Goldschmidt, Alwin Krämer, Bernard Klein, and Marc S. Raab
|
| 10237-10250 |
|
| Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γirradiation |
|
https://doi.org/10.18632/oncotarget.2500
Ying Yan, Ashley L. Hein, Asserewou Etekpo, Katrina M. Burchett, Chi Lin, Charles A. Enke, Surinder K. Batra, Kenneth H. Cowan, and Michel M. Ouellette
|
| 10251-10270 |
|
| High KIF18A expression correlates with unfavorable prognosis in primary hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.2082
Weijia Liao, Guojin Huang, Yan Liao, Jianjun Yang, Qian Chen, ShengJun Xiao, Junfei Jin, Songqing He, and Changming Wang
|
| 10271-10279 |
|
| Targeting hypoxiainducible factor1α HIF1α in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab |
|
https://doi.org/10.18632/oncotarget.2163
Gerald S. Falchook, Jennifer J. Wheler, Aung Naing, Edward F. Jackson, Filip Janku, David Hong, Chaan S. Ng, Nizar M. Tannir, Kristie N. Lawhorn, Mei Huang, Laura S. Angelo, Deeksha Vishwamitra, Kenneth Hess, Adrienne N. Howard, Kristin L. Parkhurst, Hesham M. Amin, and Razelle Kurzrock
|
| 10280-10292 |
|
| CAMK2N1 inhibits prostate cancer progression through androgen receptordependent signaling |
|
https://doi.org/10.18632/oncotarget.2511
Tao Wang, Shuiming Guo, Zhuo Liu, Licheng Wu, Mingchao Li, Jun Yang, Ruibao Chen, Xiaming Liu, Hua Xu, Shaoxin Cai, Hui Chen, Weiyong Li, Shaohua Xu, Liang Wang, Zhiquan Hu, Qianyuan Zhuang, Liping Wang, Kongming Wu, Jihong Liu, Zhangqun Ye, Jun-Yuan Ji, Chenguang Wang, and Ke Chen
|
| 10293-10306 |
|
| Overexpression of plateletderived growth factor receptor alpha promotes tumor progression and indicates poor prognosis in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.2537
Tao Wei, Li-Na Zhang, Yi Lv, Xiao-Ya Ma, Lei Zhi, Chang Liu, Feng Ma, and Xu-Feng Zhang
|
| 10307-10317 |
|
| Specific genomic and transcriptomic aberrations in tumors induced by partial hepatectomy of a chronically inflamed murine liver |
|
https://doi.org/10.18632/oncotarget.2515
Ezra Ella, Denise Heim, Evgeniy Stoyanov, Rona Harari-Steinfeld, Israel Steinfeld, Orit Pappo, Temima Schnitzer Perlman, Natalie Nachmansson, Ludmila Rivkin, Devorah Olam, Rinat Abramovitch, Henning Wege, Eithan Galun, and Daniel Goldenberg
|
| 10318-10331 |
|
| The antitumor potential of Interleukin27 in prostate cancer |
|
https://doi.org/10.18632/oncotarget.1425
Emma Di Carlo, Carlo Sorrentino, Alessia Zorzoli, Serena Di Meo, Maria Grazia Tupone, Emanuela Ognio, Gabriella Mincione, and Irma Airoldi
|
| 10332-10341 |
|
| Pharmacologic downregulation of EZH2 suppresses bladder cancer in vitro and in vivo |
|
https://doi.org/10.18632/oncotarget.1867
Shou-Hung Tang, Hsu-Shan Huang, Hong-Ui Wu, Yi-Ta Tsai, Mei-Jen Chuang, Cheng-Ping Yu, Shih-Ming Huang, Guang-Huan Sun, Sun-Yran Chang, Pei-Wen Hsiao, Dah-Shyong Yu, and Tai-Lung Cha
|
| 10342-10355 |
|
| PolyADPribosylation is involved in the epigenetic control of TET1 gene transcription |
|
https://doi.org/10.18632/oncotarget.1905
Fabio Ciccarone, Elisabetta Valentini, Maria Giulia Bacalini, Michele Zampieri, Roberta Calabrese, Tiziana Guastafierro, Germano Mariano, Anna Reale, Claudio Franceschi, and Paola Caiafa
|
| 10356-10367 |
|
| Failure of anti tumorderived endothelial cell immunotherapy depends on augmentation of tumor hypoxia |
|
https://doi.org/10.18632/oncotarget.2015
Annalisa Pezzolo, Danilo Marimpietri, Lizzia Raffaghello, Claudia Cocco, Angela Pistorio, Claudio Gambini, Michele Cilli, Alberto Horenstein, Fabio Malavasi, and Vito Pistoia
|
| 10368-10381 |
|
| p53 status as effect modifier of the association between pretreatment fasting glucose and breast cancer outcomes in non diabetic HER2 positive patients treated with trastuzumab |
|
https://doi.org/10.18632/oncotarget.2060
Patrizia Vici, Francesca Sperati, Marcello Maugeri-Saccà , Elisa Melucci, Anna Di Benedetto, Luigi Di Lauro, Laura Pizzuti, Domenico Sergi, Irene Terrenato, Luca Esposito, Carmelina Antonella Iannuzzi, Raffaella Pasquale, Claudio Botti, Barbara Fuhrman, Antonio Giordano, Marcella Mottolese, and Maddalena Barba
|
| 10382-10392 |
|
| Notch signaling drives multiple myeloma induced osteoclastogenesis |
|
https://doi.org/10.18632/oncotarget.2084
Michela Colombo, Katja Thümmler, Leonardo Mirandola, Silvia Garavelli, Katia Todoerti, Luana Apicella, Elisa Lazzari, Marialuigia Lancellotti, Natalia Platonova, Moeed Akbar, Maurizio Chiriva-Internati, Richard Soutar, Antonino Neri, Carl S. Goodyear, and Raffaella Chiaramonte
|
| 10393-10406 |
|
| Antitumor activity of S116836 a novel tyrosine kinase inhibitor against imatinibresistant FIP1L1PDGFRαexpressing cells |
|
https://doi.org/10.18632/oncotarget.2090
Yingying Shen, Xiaomei Ren, Ke Ding, Zhang Zhang, Deping Wang, and Jingxuan Pan
|
| 10407-10420 |
|
| H2AK119Ub1 and H3K27Me3 in molecular staging for survival prediction of patients with pancreatic ductal adenocarcinoma |
|
https://doi.org/10.18632/oncotarget.2126
Shi Chen, Jiangzhi Chen, Qian Zhan, Yi Zhu, Hao Chen, Xiaxing Deng, Zhaoyuan Hou, Baiyong Shen, Yanling Chen, and Chenghong Peng
|
| 10421-10433 |
|
| Mer590 a novel monoclonal antibody targeting MER receptor tyrosine kinase decreases colony formation and increases chemosensitivity in nonsmall cell lung cancer |
|
https://doi.org/10.18632/oncotarget.2142
Christopher T. Cummings, Rachel M.A. Linger, Rebecca A. Cohen, Susan Sather, Gregory D. Kirkpatrick, Kurtis D. Davies, Deborah DeRyckere, H. Shelton Earp, and Douglas K. Graham
|
| 10434-10445 |
|
| Medical treatment of orthotopic glioblastoma with transferrinconjugated nanoparticles encapsulating zoledronic acid |
|
https://doi.org/10.18632/oncotarget.2182
Manuela Porru, Silvia Zappavigna, Giuseppina Salzano, Amalia Luce, Antonella Stoppacciaro, Maria Luisa Balestrieri, Simona Artuso, Sara Lusa, Giuseppe De Rosa, Carlo Leonetti, and Michele Caraglia
|
| 10446-10459 |
|
| Efficacy of dual PI3K and mTOR inhibitors in vitro and in vivo in acute lymphoblastic leukemia |
|
https://doi.org/10.18632/oncotarget.2260
Jacky Wong, Robert Welschinger, John Hewson, Kenneth . F Bradstock, and Linda J. Bendall
|
| 10460-10472 |
|
| Thymidine phosphorylase activates NFκB and stimulates the expression of angiogenic and metastatic factors in human cancer cells |
|
https://doi.org/10.18632/oncotarget.2242
Sho Tabata, Ryuji Ikeda, Masatatsu Yamamoto, Shunji Shimaoka, Naofumi Mukaida, Yasuo Takeda, Katsushi Yamada, Tomoyoshi Soga, Tatsuhiko Furukawa, and Shin-ichi Akiyama
|
| 10473-10485 |
|
| Nicotinic acetylcholine receptors induce cKit ligand/Stem Cell Factor and promote stemness in an ARRB1/ βarrestin1 dependent manner in NSCLC |
|
https://doi.org/10.18632/oncotarget.2395
Deepak Perumal, Smitha Pillai, Jonathan Nguyen, Courtney Schaal, Domenico Coppola, and Srikumar P. Chellappan
|
| 10486-10502 |
|
| Metformin and erlotinib synergize to inhibit basal breast cancer |
|
https://doi.org/10.18632/oncotarget.2391
Ying-Ka Ingar Lau, Xing Du, Vinayak Rayannavar, Benjamin Hopkins, Jacquelyn Shaw, Eliana Bessler, Tiffany Thomas, Maira M. Pires, Megan Keniry, Ramon E. Parsons, Serge Cremers, Matthias Szabolcs, and Matthew A. Maurer
|
| 10503-10517 |
|
| RNAseq analysis reveals significant effects of EGFR signalling on the secretome of mesenchymal stem cells |
|
https://doi.org/10.18632/oncotarget.2420
Antonella De Luca, Cristin Roma, Marianna Gallo, Francesca Fenizia, Francesca Bergantino, Daniela Frezzetti, Susan Costantini, and Nicola Normanno
|
| 10518-10528 |
|
| AngioMatrix a signature of the tumor angiogenic switchspecific matrisome correlates with poor prognosis for glioma and colorectal cancer patients |
|
https://doi.org/10.18632/oncotarget.2470
Benoit Langlois, Falk Saupe, Tristan Rupp, Christiane Arnold, Michaël Van der Heyden, Gertraud Orend, and Thomas Hussenet
|
| 10529-10545 |
|
| Pharmacological targeting the ATR–CHK1–WEE1 axis involves balancing cell growth stimulation and apoptosis |
|
https://doi.org/10.18632/oncotarget.2508
Joyce P.Y. Mak, Wing Yu Man, Hoi Tang Ma, and Randy Y.C. Poon
|
| 10546-10557 |
|
| Deacetylation and degradation of HSPA5 is critical for E1A metastasis suppression in breast cancer cells |
|
https://doi.org/10.18632/oncotarget.2510
Yi-Wen Chang, Hsin-An Chen, Chi-Feng Tseng, Chih-Chen Hong, Jui-Ti Ma, Mien-Chie Hung, Chih-Hsiung Wu, Ming-Te Huang, and Jen-Liang Su
|
| 10558-10570 |
|
| SOX10 a novel HMGboxcontaining tumor suppressor inhibits growth and metastasis of digestive cancers by suppressing the Wnt/βcatenin pathway |
|
https://doi.org/10.18632/oncotarget.2512
Xin Tong, Lili Li, Xiaoyan Li, Lei Heng, Lan Zhong, Xianwei Su, Rong Rong, Shi Hu, Wenjia Liu, Baoqing Jia, Xing Liu, Geng Kou, Jun Han, Shangjing Guo, Yi Hu, Cheng Li, Qian Tao, and Yajun Guo
|
| 10571-10583 |
|
| Androgen receptor promotes gastric cancer cell migration and invasion via AKTphosphorylation dependent upregulation of matrix metalloproteinase 9 |
|
https://doi.org/10.18632/oncotarget.2513
Bao-gui Zhang, Tao Du, Ming-de Zang, Qing Chang, Zhi-yuan Fan, Jian-fang Li, Bei-qin Yu, Li-ping Su, Chen Li, Chao Yan, Qin-long Gu, Zheng-gang Zhu, Min Yan, and Bingya Liu
|
| 10584-10595 |
|
| Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5 |
|
https://doi.org/10.18632/oncotarget.2517
Malak S. Abedalthagafi, Parker H. Merrill, Wenya Linda Bi, Robert T. Jones, Marc L. Listewnik, Shakti H. Ramkissoon, Aaron R. Thorner, Ian F. Dunn, Rameen Beroukhim, Brian M. Alexander, Priscilla K. Brastianos, Joshua M. Francis, Rebecca D. Folkerth, Keith L. Ligon, Paul Van Hummelen, Azra H. Ligon, and Sandro Santagata
|
| 10596-10606 |
|
| Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR221 axis in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.2523
Catia Giovannini, Manuela Minguzzi, Michele Baglioni, Francesca Fornari, Ferdinando Giannone, Matteo Ravaioli, Matteo Cescon, Pasquale Chieco, Luigi Bolondi, and Laura Gramantieri
|
| 10607-10620 |
|
| Inhibitory effects of transcription factor Ikaros on the expression of liver cancer stem cell marker CD133 in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.2524
Lin Zhang, Hong Li, Chao Ge, Meng Li, Fang-yu Zhao, He-lei Hou, Miao-xin Zhu, Hua Tian, Li-xing Zhang, Tao-yang Chen, Guo-ping Jiang, Hai-yang Xie, Ying Cui, Ming Yao, and Jin-jun Li
|
| 10621-10635 |
|
| Downregulation of miRNA106b inhibits growth of melanoma cells by promoting G1phase cell cycle arrest and reactivation of p21/WAF1/Cip1 protein |
|
https://doi.org/10.18632/oncotarget.2527
Ram Prasad, and Santosh K. Katiyar
|
| 10636-10649 |
|
| Regulation of NADPHdependent Nitric Oxide and reactive oxygen species signalling in endothelial and melanoma cells by a photoactive NADPH analogue |
|
https://doi.org/10.18632/oncotarget.2525
Florian Rouaud, Miguel Romero-Perez, Huan Wang, Irina Lobysheva, Booma Ramassamy, Etienne Henry, Patrick Tauc, Damien Giacchero, Jean-Luc Boucher, Eric Deprez, Stéphane Rocchi, and Anny Slama-Schwok
|
| 10650-10664 |
|
| Inhibition of histone H3K79 methylation selectively inhibits proliferation selfrenewal and metastatic potential of breast cancer |
|
https://doi.org/10.18632/oncotarget.2496
Li Zhang, Lisheng Deng, Fengju Chen, Yuan Yao, Bulan Wu, Liping Wei, Qianxing Mo, and Yongcheng Song
|
| 10665-10677 |
|
| The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells |
|
https://doi.org/10.18632/oncotarget.2528
Lymor Ringer, Paul Sirajuddin, Lucas Tricoli, Sarah Waye, Muhammad Umer Choudhry, Erika Parasido, Angiela Sivakumar, Mary Heckler, Aisha Naeem, Iman Abdelgawad, Xuefeng Liu, Adam S. Feldman, Richard J. Lee, Chin-Lee Wu, Venkata Yenugonda, Bhaskar Kallakury, Anatoly Dritschilo, John Lynch, Richard Schlegel, Olga Rodriguez, Richard G. Pestell, Maria Laura Avantaggiati, and Chris Albanese
|
| 10678-10691 |
|
| Potential therapeutic effect of the secretome from human uterine cervical stem cells against both cancer and stromal cells compared with adipose tissue stem cells |
|
https://doi.org/10.18632/oncotarget.2530
Noemà Eiró, Juan Sendon-Lago, Samuel Seoane, MarÃa A. Bermúdez, Maria Luz Lamelas, Tomás Garcia-Caballero, José Schneider, Roman Perez-Fernandez, and Francisco J. Vizoso
|
| 10692-10708 |
|
| Regulation of the viability of Nf1 deficient cells by PKC isoforms |
|
https://doi.org/10.18632/oncotarget.2531
Xiaodong Zhou, Ling Shen, Toshima Parris, Junchi Huang, Bo Yi, Khalil Helou, and Changyan Chen
|
| 10709-10717 |
|
| CCL5 promotes VEGFdependent angiogenesis by downregulating miR200b through PI3K/Akt signaling pathway in human chondrosarcoma cells |
|
https://doi.org/10.18632/oncotarget.2532
Guan-Ting Liu, Hsien-Te Chen, Hsi-Kai Tsou, Tzu-Wei Tan, Yi-Chin Fong, Po-Chen Chen, Wei-Hung Yang, Shih-Wei Wang, Jui-Chieh Chen, and Chih-Hsin Tang
|
| 10718-10731 |
|
| Simultaneous targeting of PI3Kδ and a PI3Kδdependent MEK1/2Erk1/2 pathway for therapy in pediatric Bcell acute lymphoblastic leukemia |
|
https://doi.org/10.18632/oncotarget.2533
Xiang Wang, Xi Zhang, Ben-shang Li, Xiaowen Zhai, Zhuo Yang, Li-xia Ding, Hongsheng Wang, Chris Liang, Weiliang Zhu, Jian Ding, and Ling-hua Meng
|
| 10732-10744 |
|
| Resveratrol potentiates the in vitro and in vivo antitumoral effects of curcumin in head and neck carcinomas |
|
https://doi.org/10.18632/oncotarget.2534
Laura Masuelli, Enrica Di Stefano, Massimo Fantini, Rosanna Mattera, Monica Benvenuto, Laura Marzocchella, Pamela Sacchetti, Chiara Focaccetti, Roberta Bernardini, Ilaria Tresoldi, Valerio Izzi, Maurizio Mattei, Giovanni Vanni Frajese, Florigio Lista, Andrea Modesti, and Roberto Bei
|
| 10745-10762 |
|
| Fas signaling promotes chemoresistance in gastrointestinal cancer by upregulating Pglycoprotein |
|
https://doi.org/10.18632/oncotarget.2498
Haoxuan Zheng, Zhizhong Liu, Tao Liu, Yidong Cai, Yadong Wang, Shiyong Lin, Jinmin Chen, Jing Wang, Zhiqing Wang, and Bo Jiang
|
| 10763-10777 |
|
| Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer |
|
https://doi.org/10.18632/oncotarget.2502
Jianjun Tang, Gang Wang, Meifang Zhang, Feng-yan Li, Yi Sang, Boqing Wang, Kaishun Hu, Yuanzhong Wu, Rongzhen Luo, Dan Liao, Jingying Cao, Xin Wang, Li Wang, Ruhua Zhang, Xiaoshi Zhang, Wu-Guo Deng, Dan Xie, Rui-hua Xu, and Tiebang Kang
|
| 10778-10790 |
|
| Induction of a specific CD8+ Tcell response to cancer/testis antigens by demethylating pretreatment against osteosarcoma |
|
https://doi.org/10.18632/oncotarget.2505
Binghao Li, Xiaobing Zhu, Lingling Sun, Li Yuan, Jian Zhang, Hengyuan Li, and Zhaoming Ye
|
| 10791-10802 |
|
| Oct4 and nanog promote the epithelialmesenchymal transition of breast cancer stem cells and are associated with poor prognosis in breast cancer patients |
|
https://doi.org/10.18632/oncotarget.2506
Dan Wang, Ping Lu, Hao Zhang, Minna Luo, Xin Zhang, Xiaofei Wei, Jiyue Gao, Zuowei Zhao, and Caigang Liu
|
| 10803-10815 |
|
| miR145 inhibits tumor growth and metastasis by targeting metadherin in highgrade serous ovarian carcinoma |
|
https://doi.org/10.18632/oncotarget.2522
Ruifen Dong, Xiaolin Liu, Qing Zhang, Zhijun Jiang, Yingwei Li, Yuyan Wei, Yinuo Li, Qifeng Yang, Jinsong Liu, Jian-Jun Wei, Changshun Shao, Zhaojian Liu, and Beihua Kong
|
| 10816-10829 |
|
| A novel drug discovery strategy: Mechanistic investigation of an enantiomeric antitumor agent targeting dual p53 and NFκB pathways |
|
https://doi.org/10.18632/oncotarget.2521
Chunlin Zhuang, Chunquan Sheng, Woo Shik Shin, Yuelin Wu, Jin Li, Jianzhong Yao, Guoqiang Dong, Wen Zhang, Yuk Yin Sham, Zhenyuan Miao, and Wannian Zhang
|
| 10830-10839 |
|
| CDKL2 promotes epithelialmesenchymal transition and breast cancer progression |
|
https://doi.org/10.18632/oncotarget.2535
Linna Li, Chunping Liu, Robert J. Amato, Jeffrey T. Chang, Wenliang Li, and Wenliang Li
|
| 10840-10853 |
|
| Stromal TGFβ signaling induces AR activation in prostate cancer |
|
https://doi.org/10.18632/oncotarget.2536
Feng Yang, Yizhen Chen, Tao Shen, Dan Guo, Olga Dakhova, Michael M. Ittmann, Chad J. Creighton, Yiqun Zhang, Truong D. Dang, and David R. Rowley
|
| 10854-10869 |
|
| Msi1 promotes tumor growth and cell proliferation by targeting cell cycle checkpoint proteins p21 p27 and p53 in cervical carcinomas |
|
https://doi.org/10.18632/oncotarget.2539
Xian Liu, Wen-Ting Yang, and Peng-Sheng Zheng
|
| 10870-10885 |
|
| The ubiquitin E3 ligase ITCH enhances breast tumor progression by inhibiting the Hippo tumor suppressor pathway |
|
https://doi.org/10.18632/oncotarget.2540
Zaidoun Salah, Ella Itzhaki, and Rami I. Aqeilan
|
| 10886-10900 |
|
| Downregulation of BRCA1BRCA2containing complex subunit 3 sensitizes glioma cells to temozolomide |
|
https://doi.org/10.18632/oncotarget.2543
Kit Man Chai, Chih-Yen Wang, Hung-Jiun Liaw, Kuan-Min Fang, Chung-Shi Yang, and Shun-Fen Tzeng
|
| 10901-10915 |
|
| Angiostatic tumor inflammatory and antitumor effects of CXCL44770 and CXCL4L14770 in an EGFdependent breast cancer model |
|
https://doi.org/10.18632/oncotarget.2538
Katrien Van Raemdonck, Nele Berghmans, Vincent Vanheule, Antonella Bugatti, Paul Proost, Ghislain Opdenakker, Marco Presta, Jo Van Damme, and Sofie Struyf
|
| 10916-10933 |
|
| Proscillaridin A is cytotoxic for glioblastoma cell lines and controls tumor xenograft growth in vivo |
|
https://doi.org/10.18632/oncotarget.2541
Emilie Denicolaï, Nathalie Baeza-Kallee, Aurélie Tchoghandjian, Manon Carré, Carole Colin, Carine Jiguet Jiglaire, Sandy Mercurio, Christophe Beclin, and Dominique Figarella-Branger
|
| 10934-10948 |
|
| An NCR1based chimeric receptor endows Tcells with multiple antitumor specificities |
|
https://doi.org/10.18632/oncotarget.1919
Yair Tal, Shlomo Yaakobi, Miryam Horovitz-Fried, Einav Safyon, Benyamin Rosental, Angel Porgador, and Cyrille J. Cohen
|
| 10949-10958 |
