Combined BRAF^V600E- and SRC-inhibition induces apoptosis, evokes an immune response and reduces tumor growth in an immunocompetent orthotopic mouse model of anaplastic thyroid cancer

An interferon signature identified by RNA-sequencing of mammary tissues varies across the estrous cycle and is predictive of metastasis-free survival

A genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas

Week one FLT-PET response predicts complete remission to R-CHOP and survival in DLBCL

Potential clinical implications of BRAF mutations in histiocytic proliferations

Heme-oxygenase-1 implications in cell morphology and the adhesive behavior of prostate cancer cells

Silencing of LINE-1 retrotransposons contributes to variation in small noncoding RNA expression in human cancer cells

Artesunate overcomes drug resistance in multiple myeloma by inducing mitochondrial stress and non-caspase apoptosis

Metformin-induced metabolic reprogramming of chemoresistant ALDH^bright breast cancer cells

Loss of tumor suppressor mir-203 mediates overexpression of LIM and SH3 Protein 1 (LASP1) in high-risk prostate cancer thereby increasing cell proliferation and migration

Urokinase receptor promotes ovarian cancer cell dissemination through its 84-95 sequence

The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells

Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells

Repression of liver colorectal metastasis by the serpin Spn4A a naturally occurring inhibitor of the constitutive secretory proprotein convertases

SCF^β-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination

PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells

Post-translational regulation of COX2 activity by FYN in prostate cancer cells

Reduced ING1 levels in breast cancer promotes metastasis

Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1

Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer

Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment

Relevance of IGFBP2 proteolysis in glioma and contribution of the extracellular protease ADAMTS1

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

High nuclear level of Vav1 is a positive prognostic factor in early invasive breast tumors: a role in modulating genes related to the efficiency of metastatic process

XIAP inhibitors induce differentiation and impair clonogenic capacity of acute myeloid leukemia stem cells

Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3

DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response

SCF^FBXW7α modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stability

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines

NOX4 promotes non-small cell lung cancer cell proliferation and metastasis through positive feedback regulation of PI3K/Akt signaling

Rac1 regulates skin tumors by regulation of keratin 17 through recruitment and interaction with CD11b+Gr1+ cells

Thymocyte selection-associated high mobility group box gene (TOX) is aberrantly over-expressed in mycosis fungoides and correlates with poor prognosis

Apelin promotes lymphangiogenesis and lymph node metastasis

20(S)-Ginsenoside Rg₃ is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin

Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells

Host defense peptides for treatment of colorectal carcinoma – a comparative in vitro and in vivo analysis

PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia

Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding

New histone deacetylase inhibitors improve cisplatin antitumor properties against thoracic cancer cells

Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals

Icotinib antagonizes ABCG2-mediated multidrug resistance, but not the pemetrexed resistance mediated by thymidylate synthase and ABCG2

Discovery of novel non-ATP competitive FGFR1 inhibitors and evaluation of their anti-tumor activity in non-small cell lung cancer in vitro and in vivo

Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB

Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancer in vivo and in vitro through elevating p21 and ROS levels