About The Cover
Molecular docking of DNMT inhibitors to AID. The best insertion model is presented by a ribbon (not shown) and surface model (cover). See Ching-Chow Chen et al.
Table of Contents
Editorial Materials
Plasticity of melanoma and EMT-TF reprogramming
| Plasticity of melanoma and EMT-TF reprogramming |
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https://doi.org/10.18632/oncotarget.1662 Eugene Tulchinsky, J. Howard Pringle, Julie Caramel, and Stéphane Ansieau |
| 1-2 |
| PDF | How to cite |
DNp73: oncotarget in invasion and metastasis
| DNp73: oncotarget in invasion and metastasis |
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https://doi.org/10.18632/oncotarget.1746 Brigitte M. Pützer |
| 3-4 |
| PDF | How to cite |
Breaking Bad: how does a neuronal protein cause neuroendocrine cancer?
| Breaking Bad: how does a neuronal protein cause neuroendocrine cancer? |
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https://doi.org/10.18632/oncotarget.1710 Karine Pozo, Fiemu E. Nwariaku, and James A Bibb |
| 5-6 |
| PDF | How to cite |
A long lasting puzzle for −7/7q− syndrome
| A long lasting puzzle for −7/7q− syndrome |
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https://doi.org/10.18632/oncotarget.1763 Hiroaki Honda, and Toshiya Inaba |
| 7-8 |
| PDF | How to cite |
Spherical nucleic acids for precision medicine
| Spherical nucleic acids for precision medicine |
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https://doi.org/10.18632/oncotarget.1757 Chad A. Mirkin, and Alexander H. Stegh |
| 9-10 |
| PDF | How to cite |
Reviews
Targeting nucleocytoplasmic transport in cancer therapy
| Targeting nucleocytoplasmic transport in cancer therapy |
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https://doi.org/10.18632/oncotarget.1457 Richard Hill, Bastien Cautain, Nuria de Pedro, and Wolfgang Link |
| 11-28 |
| Abstract | PDF | HTML | How to cite |
Krüppel-like factors in cancer progression: three fingers on the steering wheel.
| Krüppel-like factors in cancer progression: three fingers on the steering wheel. |
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https://doi.org/10.18632/oncotarget.1456 Ridha Limame, Ken Op de Beeck, Filip Lardon, Olivier De Wever, and Patrick Pauwels |
| 29-48 |
| Abstract | PDF | HTML | How to cite |
mTOR pathway in colorectal cancer: an update
| mTOR pathway in colorectal cancer: an update |
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https://doi.org/10.18632/oncotarget.1548 Maria Giovanna Francipane, and Eric Lagasse |
| 49-66 |
| Abstract | PDF | HTML | How to cite |
NF2/Merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations
| NF2/Merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations |
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https://doi.org/10.18632/oncotarget.1557 Rebecca Dunbar Schroeder, Laura S. Angelo, and Razelle Kurzrock |
| 67-77 |
| Abstract | PDF | HTML | How to cite |
Perspectives of TGF-β inhibition in pancreatic and hepatocellular carcinomas
| Perspectives of TGF-β inhibition in pancreatic and hepatocellular carcinomas |
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https://doi.org/10.18632/oncotarget.1569 Cindy Neuzillet, Armand de Gramont, Annemilaï Tijeras-Raballand, Louis de Mestier, Jérôme Cros, Sandrine Faivre, and Eric Raymond |
| 78-94 |
| Abstract | PDF | HTML | How to cite |
Brief Reports
A novel immunomodulatory and molecularly targeted strategy for refractory Hodgkin’s lymphoma
| A novel immunomodulatory and molecularly targeted strategy for refractory Hodgkin’s lymphoma |
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https://doi.org/10.18632/oncotarget.1468 Vivek Subbiah, Robert E. Brown, Mary F. McGuire, Jamie Buryanek, Filip Janku, Anas Younes, and David Hong |
| 95-102 |
| Abstract | PDF | HTML | How to cite |
The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model
| The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model |
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https://doi.org/10.18632/oncotarget.1560 Sebastian Kobold, Melanie Merk, Luisa Hofer, Philip Peters, Richard Bucala, and Stefan Endres |
| 103-107 |
| Abstract | PDF | HTML | How to cite |
Research Papers
Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice
| Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice |
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https://doi.org/10.18632/oncotarget.1171 Marianna L Ianzano, Stefania Croci, Giordano Nicoletti, Arianna Palladini, Lorena Landuzzi, Valentina Grosso, Dario Ranieri, Massimiliano Dall'Ora, Ilaria Santeramo, Milena Urbini, Carla De Giovanni, Pier Luigi Lollini, and Patrizia Nanni |
| 108-119 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia
| MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia |
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https://doi.org/10.18632/oncotarget.1337 Annalisa Astolfi, Francesca Vendemini, Milena Urbini, Fraia Melchionda, Riccardo Masetti, Monica Franzoni, Virginia Libri, Salvatore Serravalle, Marco Togni, Giuseppina Paone, Luca Montemurro, Daniela Bressanin, Francesca Chiarini, Alberto M Martelli, Roberto Tonelli, and Andrea Pession |
| 120-130 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation
| A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation |
|
https://doi.org/10.18632/oncotarget.1405 Jennifer Munkley, Prabhakar Rajan, Nicholas P. Lafferty, Caroline Dalgliesh, Robert M. Jackson, Craig N. Robson, Hing Y. Leung, and David J. Elliott |
| 131-139 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Genetic subclonal complexity and miR125a-5p down-regulation identify a subset of patients with inferior outcome in low-risk CLL patients
| Genetic subclonal complexity and miR125a-5p down-regulation identify a subset of patients with inferior outcome in low-risk CLL patients |
|
https://doi.org/10.18632/oncotarget.1382 Gian Matteo Rigolin, Elena Saccenti, Lara Rizzotto, Manuela Ferracin, Sara Martinelli, Luca Formigaro, Francesca Cibien, Maurizio Cavallari, Enrico Lista, Giulia Daghia, Olga Sofritti, Maria Ciccone, Francesco Cavazzini, Laura Lupini, Cristian Bassi, Barbara Zagatti, Massimo Negrini, and Antonio Cuneo |
| 140-149 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Survivin promoter-regulated oncolytic adenovirus with Hsp70 gene exerts effective antitumor efficacy in gastric cancer immunotherapy
| Survivin promoter-regulated oncolytic adenovirus with Hsp70 gene exerts effective antitumor efficacy in gastric cancer immunotherapy |
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https://doi.org/10.18632/oncotarget.1430 Weiguo Wang, Weidan Ji, Huanzhang Hu, Juming Ma, Xiaoya Li, Weiqun Mei, Yang Xu, Hui-Zhen Hu, Yan Yan, Qizhe Song, Zhigang Li, and Changqing Su |
| 150-160 |
| Abstract | PDF | HTML | How to cite |
Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma
| Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma |
|
https://doi.org/10.18632/oncotarget.1083 Jennifer K Wolter, Nikolaus E Wolter, Alvaro Blanch, Teresa Partridge, Lynn Cheng, Daniel A. Morgenstern, Monika Podkowa, David R. Kaplan, and Meredith S. Irwin |
| 161-172 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death
| Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death |
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https://doi.org/10.18632/oncotarget.1500 Eran Schmukler, Eya Wolfson, Roni Haklai, Galit Elad-Sfadia, Yoel Kloog, and Ronit Pinkas-Kramarski |
| 173-184 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
The proto-oncogene KRAS is targeted by miR-200c
| The proto-oncogene KRAS is targeted by miR-200c |
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https://doi.org/10.18632/oncotarget.1427 Florian Kopp, Ernst Wagner, and Andreas Roidl |
| 185-195 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-кB target genes in human breast cancer
| Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-кB target genes in human breast cancer |
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https://doi.org/10.18632/oncotarget.1556 Alba Dalmases, Irene Gonzalez-Navarrete, Silvia Menendez, Oriol Arpí, Josep Maria Coromines, Sonia Servitja, Ignasi Tusquets, Cristina Chamizo, Raúl Rincón, Lluís Espinosa, Anna Bigas, Pilar Eroles, Jessica Furriol, Anna Lluch, Ana Rovira, Joan Albanell, and Federico Rojo |
| 196-210 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine
| AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine |
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https://doi.org/10.18632/oncotarget.1319 Chiou-Tsun Tsai, Pei-Ming Yang, Ting-Rong Chern, Shu-Hui Chuang, Jung-Hsin Lin, Lars Klemm, Markus Müschen, and Ching-Chow Chen |
| 211-223 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
A TRAF2 binding independent region of TNFR2 is responsible for TRAF2 depletion and enhancement of cytotoxicity driven by TNFR1
| A TRAF2 binding independent region of TNFR2 is responsible for TRAF2 depletion and enhancement of cytotoxicity driven by TNFR1 |
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https://doi.org/10.18632/oncotarget.1492 Lucía Cabal-Hierro, Noelia Artime, Julián Iglesias, Miguel A. Prado, Lorea Ugarte-Gil, Pedro Casado, Belén Fernández-García, Bryant G. Darnay, and Pedro S. Lazo |
| 224-236 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry
| Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry |
|
https://doi.org/10.18632/oncotarget.1599 Christine B. Ambrosone, Allyson C. Young, Lara E. Sucheston, Dan Wang, Li Yan, Song Liu, Li Tang, Qiang Hu, Jo L. Freudenheim, Peter G. Shields, Carl D. Morrison, Kitaw Demissie, and Michael J. Higgins |
| 237-248 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Overexpression of 14-3-3θ promotes tumor metastasis and indicates poor prognosis in breast carcinoma
| Overexpression of 14-3-3θ promotes tumor metastasis and indicates poor prognosis in breast carcinoma |
|
https://doi.org/10.18632/oncotarget.1502 Nanlin Li, Hui Wang, Fan Jing, Chao Tong, Jixin Yang, Hongliang Wei, Jun Yi, and Rui Ling |
| 249-257 |
| Abstract | PDF | HTML | How to cite |
Targeting chronic lymphocytic leukemia using CIGB-300, a clinical-stage CK2-specific cell-permeable peptide inhibitor
| Targeting chronic lymphocytic leukemia using CIGB-300, a clinical-stage CK2-specific cell-permeable peptide inhibitor |
|
https://doi.org/10.18632/oncotarget.1513 Leila R. Martins, Yasser Perera, Paulo Lúcio, Maria G. Silva, Silvio E. Perea, and João T. Barata |
| 258-263 |
| Abstract | PDF | HTML | How to cite |
FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis.
| FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. |
|
https://doi.org/10.18632/oncotarget.1600 Bee Shin Tan, Matthew R Anaka, Siddhartha Deb, Claudia Freyer, Lisa M Ebert, Anderly C Chueh, Sheren Al-Obaidi, Andreas Behren, Aparna Jayachandran, Jonathan Cebon, Weisan Chen, and John M Mariadason |
| 264-276 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling
| Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling |
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https://doi.org/10.18632/oncotarget.1696 Hendrik Ungefroren, Susanne Sebens, Klaudia Giehl, Ole Helm, Stephanie Groth, Fred Faendrich, Christoph Roecken, Bence Sipos, Hendrik Lehnert, and Frank Gieseler |
| 277-290 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Poly (ADP-ribose) polymerase 1 transcriptional regulation: A novel crosstalk between histone modification H3K9ac and ETS1 motif hypomethylation in BRCA1-mutated ovarian cancer
| Poly (ADP-ribose) polymerase 1 transcriptional regulation: A novel crosstalk between histone modification H3K9ac and ETS1 motif hypomethylation in BRCA1-mutated ovarian cancer |
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https://doi.org/10.18632/oncotarget.1549 Da Li, Fang-Fang Bi, Ji-Min Cao, Chen Cao, Chun-Yan Li, Bo Liu, and Qing Yang |
| 291-297 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress
| Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress |
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https://doi.org/10.18632/oncotarget.1628 Yu-Chin Lin, Meng-Hsuan Wu, Tzu-Tang Wei, Yun-Chieh Lin, Wen-Chih Huang, Liang-Yu Huang, Yi-Ting Lin, and Ching-Chow Chen |
| 298-308 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
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