Oncotarget

Volume 4, Issue 5

May 2013

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About The Cover

The potential interplay between mesenchymal stem cells and tumor microenvironment. See Droujinine, Eckert, Zhao. Larger Image.

Table of Contents

Editorial

Reaching Un-Drugable Intracellular Targets with the Long Arm of Antibodies

Reaching Un-Drugable Intracellular Targets with the Long Arm of Antibodies

https://doi.org/10.18632/oncotarget.1039

David A. Scheinberg, Tao Dao,  and Cheng Liu
647-648
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Perturbation of nucleotide metabolism - the driving force of oncogene-induced senescence

Perturbation of nucleotide metabolism - the driving force of oncogene-induced senescence

https://doi.org/10.18632/oncotarget.1023

Zbigniew Darzynkiewicz
649-650
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Reviews

To grab the stroma by the horns: From biology to cancer therapy with mesenchymal stem cells

To grab the stroma by the horns: From biology to cancer therapy with mesenchymal stem cells

https://doi.org/10.18632/oncotarget.1040

Ilia A. Droujinine, Mark A Eckert,  and Weian Zhao
651-664
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Research Papers

MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1

MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1

https://doi.org/10.18632/oncotarget.928

Ariel Bier, Niss Giladi, Noam Kronfeld, Hae Kyung Lee, Simona Cazacu, Susan Finniss, Cunli Xiang, Laila Poisson, Ana C deCarvalho, Shimon Slavin, Elad Jacoby, Michal Yalon, Amos Toren, Tom Mikkelsen,  and Chaya Brodie
665-676
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Cell death sensitization of leukemia cells by opioid receptor activation

Cell death sensitization of leukemia cells by opioid receptor activation

https://doi.org/10.18632/oncotarget.952

Claudia Friesen, Mareike Roscher, Inis Hormann, Iduna Fichtner, Andreas Alt, Ralf Hilger, Klaus-Michael Debatin,  and Erich Miltner
677-690
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Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors

Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors

https://doi.org/10.18632/oncotarget.975

Joanna L Gillis, Luke A Selth, Margaret M Centenera, Scott L Townley, Shihua Sun, Stephen R Plymate, Wayne D Tilley,  and Lisa M Butler
691-704
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy

https://doi.org/10.18632/oncotarget.974

Rabih Said, David S. Hong, Carla L. Warneke, J. Jack Lee, Jennifer J. Wheler, Filip Janku, Aung Naing, Gerald S. Falchook, Siqing Fu, Sarina Piha-Paul, Apostolia M. Tsimberidou,  and Razelle Kurzrock
705-714
Abstract  |  PDF  |  HTML  |  How to cite

Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations

Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations

https://doi.org/10.18632/oncotarget.990

Jonathan M. Gerber, Jessica L. Gucwa, David Esopi, Meltem Gurel, Michael C. Haffner, Milada Vala, William G. Nelson, Richard J. Jones,  and Srinivasan Yegnasubramanian
715-728
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies.

FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies.

https://doi.org/10.18632/oncotarget.1027

Rocky Cipriano, Kristy L.S. Miskimen, Benjamin L. Bryson, Chase R. Foy, Courtney A. Bartel,  and Mark W Jackson
729-738
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer

Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer

https://doi.org/10.18632/oncotarget.1034

Xiao-Yang Wang, Huina Yu, R. Ilona Linnpoila, Laodong Li, Dangyu Li, Biwen Bo, Hideyuki Okano, Luis O.F. Penalva,  and Robert I Glazer
739-750
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Powerful Inhibition of Experimental Human Pancreatic Cancers by Receptor Targeted Cytotoxic LH-RH analog AEZS-108

Powerful Inhibition of Experimental Human Pancreatic Cancers by Receptor Targeted Cytotoxic LH-RH analog AEZS-108

https://doi.org/10.18632/oncotarget.1044

Karoly Szepeshazi, Andrew V. Schally, Norman L. Block, Gabor Halmos, Mehrdad Nadji, Luca Szalontay, Irving Vidaurre, Andrew Abi-Chaker,  and Ferenc G. Rick
751-760
Abstract  |  PDF  |  HTML  |  How to cite

Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma

Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma

https://doi.org/10.18632/oncotarget.1047

Ryan T Pitman, Luke Wojdyla,  and Neelu Puri
761-771
Abstract  |  PDF  |  HTML  |  How to cite

Revisiting Clinical Trials Using EGFR Inhibitor-Based Regimens in Patients with Advanced Non-Small Cell Lung Cancer: A Retrospective Analysis of an MD Anderson Cancer Center Phase I Population

Revisiting Clinical Trials Using EGFR Inhibitor-Based Regimens in Patients with Advanced Non-Small Cell Lung Cancer: A Retrospective Analysis of an MD Anderson Cancer Center Phase I Population

https://doi.org/10.18632/oncotarget.1028

Jennifer Wheler, Gerald Falchook, Apostolia M. Tsimberidou, David Hong, Aung Naing, Sarina Piha-Paul, Su S. Chen, John Heymach, Siqing Fu, Su S. Chen, Bettzy Stephen, Jansina Y. Fok, Filip Janku,  and Razelle Kurzrock
772-784
Abstract  |  PDF  |  HTML  |  How to cite

CD44variant exon 9 plays an important role in colon cancer initiating cells

CD44variant exon 9 plays an important role in colon cancer initiating cells

https://doi.org/10.18632/oncotarget.1048

Youhei Kimura, Takanori Goi, Toshiyuki Nakazawa, Yasuo Hirono, Kanji Katayama, Takeshi Urano,  and Akio Yamaguchi
785-791
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Brain Tumor Stem Cell Multipotency Correlates with Nanog Expression and Extent of Passaging in Human Glioblastoma Xenografts

Brain Tumor Stem Cell Multipotency Correlates with Nanog Expression and Extent of Passaging in Human Glioblastoma Xenografts

https://doi.org/10.18632/oncotarget.1059

Dominique M. Higgins, Ruisi Wang, Brian Milligan, Mark Schroeder, Brett Carlson, Jenny Pokorny, Samuel H. Cheshier, Fredric B. Meyer, Irving L. Weissman, Jann N. Sarkaria,  and John R. Henley
792-801
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite


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