About The Cover
The October cover of Oncotarget depicts a phenotype of zebrafish injected with CIC MO. The knock-down of CIC results in mitochondrial DNA depletion and activation of autophagy. See Catalina-Rodriguez et al.
Table of Contents
Editorial
Targeting SHP2 phosphatase in Myeloproliferative Neoplasms
| Targeting SHP2 phosphatase in Myeloproliferative Neoplasms |
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https://doi.org/10.18632/oncotarget.665 Raghuveer Singh Mali, Rebecca Chan, and Reuben Kapur |
| 1049-1051 |
| PDF | HTML | How to cite |
p53 as a target in myeloproliferative neoplasms
| p53 as a target in myeloproliferative neoplasms |
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https://doi.org/10.18632/oncotarget.719 Min Lu, and Ronald Hoffman |
| 1052-1053 |
| PDF | HTML | How to cite |
Inhibiting the molecular evolution of cancer through HSP90
| Inhibiting the molecular evolution of cancer through HSP90 |
|
https://doi.org/10.18632/oncotarget.738 Ana Sofia Martins, Faith E. Davies, and Paul Workman |
| 1054-1056 |
| PDF | HTML | How to cite |
Regulation of p53 by Helicobacter pylori
| Regulation of p53 by Helicobacter pylori |
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https://doi.org/10.18632/oncotarget.698 Alexander Zaika, Jinxiong Wei, Jennifer Noto, and Richard Peek, Jr |
| 1057-1058 |
| PDF | HTML | How to cite |
HLX in AML: novel prognostic and therapeutic target
| HLX in AML: novel prognostic and therapeutic target |
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https://doi.org/10.18632/oncotarget.705 Ashley Pandolfi, and Ulrich Steidl |
| 1059-1060 |
| PDF | HTML | How to cite |
Exploiting the mTOR paradox for disease prevention
| Exploiting the mTOR paradox for disease prevention |
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https://doi.org/10.18632/oncotarget.712 Ramiro Iglesias-Bartolome, and J. Silvio Gutkind |
| 1061-1063 |
| PDF | HTML | How to cite |
Too much AKT turns PAX3-FKHR dead: A prospect of novel therapeutic strategy for alveolar rhabdomyosarcoma
| Too much AKT turns PAX3-FKHR dead: A prospect of novel therapeutic strategy for alveolar rhabdomyosarcoma |
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https://doi.org/10.18632/oncotarget.713 Mathivanan Jothi, and Asoke K. Mal |
| 1064-1065 |
| PDF | HTML | How to cite |
Burkitt lymphomagenesis linked to MYC plus PI3K in germinal center B cells
| Burkitt lymphomagenesis linked to MYC plus PI3K in germinal center B cells |
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https://doi.org/10.18632/oncotarget.726 Sandrine Sander, and Klaus Rajewsky |
| 1066-1067 |
| PDF | HTML | How to cite |
Reviews
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance
| Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance |
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https://doi.org/10.18632/oncotarget.659 James Andrew McCubrey, Linda S. Steelman, William H. Chappell, Stephen L. Abrams, Richard A. Franklin, Giuseppe Montalto, Melchiorre Cervello, Massimo Libra, Saverio Candido, Grazia Malaponte, Maria C. Mazzarino, Paolo Fagone, Ferdinando Nicoletti, Jörg Bäsecke, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Michele Milella, Agostino Tafuri, Francesca Chiarini, Camilla Evangelisti, Lucio Cocco, and Alberto M. Martelli |
| 1068-1111 |
| Abstract | PDF | HTML | How to cite |
Research: Complementary Reports
Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide
| Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide |
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https://doi.org/10.18632/oncotarget.604 Joanna Triscott, Cathy Lee, Kaiji Hu, Abbas Fotovati, Rachel Berns, Mary Pambid, Margaret Luk, Richard E Kast, Esther Kong, Eric Toyota, Stephen Yip, Brian Toyota, and Sandra E Dunn |
| 1112-1123 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
High-Throughput Chemical Screens Identify Disulfiram as an Inhibitor of Human Glioblastoma Stem Cells
| High-Throughput Chemical Screens Identify Disulfiram as an Inhibitor of Human Glioblastoma Stem Cells |
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https://doi.org/10.18632/oncotarget.707 Parvinder Hothi, Timothy J. Martins, LiPing Chen, Loic Deleyrolle, Jae-Geun Yoon, Brent Reynolds, and Greg Foltz |
| 1124-1136 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Research Papers
High cytidine deaminase expression in the liver provides sanctuary for cancer cells from decitabine treatment effects
| High cytidine deaminase expression in the liver provides sanctuary for cancer cells from decitabine treatment effects |
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https://doi.org/10.18632/oncotarget.597 Quteba Ebrahem, Reda Z Mahfouz, Kwok Peng Ng, and Yogen Saunthararajah |
| 1137-1145 |
| Abstract | PDF | HTML | How to cite |
FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration
| FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration |
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https://doi.org/10.18632/oncotarget.644 Véronique Frattini, Federica Pisati, Maria Carmela Speranza, Pietro Luigi Poliani, Gianmaria Frigé, Gabriele Cantini, Dimos Kapetis, Manuela Cominelli, Alessandra Rossi, Gaetano Finocchiaro, and Serena Pellegatta |
| 1146-1157 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Heat Shock Protein 90 is overexpressed in high-risk myelodysplastic syndromes and associated with higher expression and activation of Focal Adhesion Kinase
| Heat Shock Protein 90 is overexpressed in high-risk myelodysplastic syndromes and associated with higher expression and activation of Focal Adhesion Kinase |
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https://doi.org/10.18632/oncotarget.557 Pascale Flandrin-Gresta, Francoise Solly, Carmen Mariana Aanei, Jerome Cornillon, Emmanuelle Tavernier, Nathalie Nadal, Franck Morteux, Denis Guyotat, Eric Wattel, and Lydia Campos |
| 1158-1168 |
| Abstract | PDF | HTML | How to cite |
Targeting JNK-interacting-protein-1 (JIP1) sensitises osteosarcoma to doxorubicin
| Targeting JNK-interacting-protein-1 (JIP1) sensitises osteosarcoma to doxorubicin |
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https://doi.org/10.18632/oncotarget.600 Jantine Posthuma De Boer, Pim W. van Egmond, Marco N. Helder, Renée X. de Menezes, Anne-Marie Cleton-Jansen, Jeroen A.M. Beliën, Henk M.W. Verheul, Barend J. van Royen, Gert-Jan J.L. Kaspers, and Victor W. van Beusechem |
| 1169-1181 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Up-regulation of c-MYC and SIRT1 expression correlates with malignant transformation in the serrated route to colorectal cancer
| Up-regulation of c-MYC and SIRT1 expression correlates with malignant transformation in the serrated route to colorectal cancer |
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https://doi.org/10.18632/oncotarget.628 Lydia Kriegl, Michael Vieth, Thomas Kirchner, and Antje Menssen |
| 1182-1193 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma
| Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma |
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https://doi.org/10.18632/oncotarget.689 Kasthuri Kannan, Akiko Inagaki, Joachim Silber, Daniel Gorovets, Jianan Zhang, Edward R. Kastenhuber, Adriana Heguy, John H. Petrini, Timothy A. Chan, and Jason T. Huse |
| 1194-1203 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: Emergence of new molecular targets.
| Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: Emergence of new molecular targets. |
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https://doi.org/10.18632/oncotarget.679 Pamela L. Strissel, Matthias Ruebner, Falk Thiel, David Wachter, Arif B. Ekici, Friedericke Wolf, Franziska Thieme, Klemens Ruprecht, Matthias W. Beckmann, and Reiner Strick |
| 1204-1219 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis.
| The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis. |
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https://doi.org/10.18632/oncotarget.714 Olga Catalina-Rodriguez, Vamsi K. Kolukula, York Tomita, Anju Preet, Ferdinando Palmieri, Anton Wellstein, Stephen Byers, Amato J. Giaccia, Eric Glasgow, Chris Albanese, and Maria Laura Avantaggiati |
| 1220-1235 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
Effects of Ectopic Expression of NGAL on Doxorubicin Sensitivity.
| Effects of Ectopic Expression of NGAL on Doxorubicin Sensitivity. |
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https://doi.org/10.18632/oncotarget.691 William H Chappell, Stephen L. Abrams, Richard A Franklin, Giuseppe Montalto, Melchiorre Cervello, Alberto M Martelli, Saverio Candido, Massimo Libra, Jerry Polesel, Renato Talamini, Ralph Arlinghaus, Linda S Steelman, and James A McCubrey |
| 1236-1245 |
| Abstract | PDF | HTML | How to cite |
DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma
| DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma |
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https://doi.org/10.18632/oncotarget.675 Nicola Amodio, Marzia Leotta, Dina Bellizzi, Maria Teresa Di Martino, Patrizia D'Aquila, Marta Lionetti, Fernanda Fabiani, Emanuela Leone, Anna Maria Gullà, Giuseppe Passarino, Michele Caraglia, Massimo Negrini, Antonino Neri, Antonio Giordano, Pierosandro Tagliaferri, and Pierfrancesco Tassone |
| 1246-1258 |
| Abstract | PDF | HTML | Supplementary Information | How to cite |
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