Oncotarget

Volume 15 (2024)

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Table of Contents

Research Papers

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines

https://doi.org/10.18632/oncotarget.28551

Mathew Lozinski, Nikola A. Bowden, Moira C. Graves, Michael Fay, Bryan W. Day, Brett W. Stringer,  and Paul A. Tooney
1-18
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: Decreased long intergenic noncoding RNA P7 predicts unfavorable prognosis and promotes tumor proliferation via the modulation of the STAT1-MAPK pathway in hepatocellular carcinoma

Retraction: Decreased long intergenic noncoding RNA P7 predicts unfavorable prognosis and promotes tumor proliferation via the modulation of the STAT1-MAPK pathway in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.28366

Sijie Cheng, Tieling Li, Cheng Wang, Keyu Wang, Chengcai Lai, Jin Yan, Hongxia Fan, Fang Sun, Zhaohai Wang, Peirui Zhang, Linxiang Yu, Zhixian Hong, Guanglin Lei, Baijun Sun, Yuan Gao, Zhaohui Xiao, Xu Ji, Ruilan Wang, Jianzhong Wu, Xiliang Wang, Shaogeng Zhang,  and Penghui Yang
19-19
Retraction  |  PDF  |  How to cite

Research Perspectives

Bone marrow adipocytes provide early sign for progression from MGUS to multiple myeloma

Bone marrow adipocytes provide early sign for progression from MGUS to multiple myeloma

https://doi.org/10.18632/oncotarget.28548

Bilal M. El-Masri, Benedeta Leka, Fatima Mustapha, Michael Tveden Gundesen, Maja Hinge, Thomas Lund, Thomas L. Andersen, Marta Diaz-delCastillo,  and Abbas Jafari
20-26
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Case Reports

Lazarus effect in a patient initially empirically treated with osimertinib for EGFR L858R mutant non-small cell lung cancer with leptomeningeal disease: a case report

Lazarus effect in a patient initially empirically treated with osimertinib for EGFR L858R mutant non-small cell lung cancer with leptomeningeal disease: a case report

https://doi.org/10.18632/oncotarget.28550

Shreya Bhatia, Manuel G. Cortez, Spencer Lessans,  and Wade T. Iams
27-30
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

The fate of drug discovery in academia; dumping in the publication landfill?

The fate of drug discovery in academia; dumping in the publication landfill?

https://doi.org/10.18632/oncotarget.28552

Uzma Saqib, Isaac S. Demaree, Alexander G. Obukhov, Mirza S. Baig, Amiram Ariel,  and Krishnan Hajela
31-34
PDF  |  How to cite  |  Press Release

Retraction

Retraction: Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice

Retraction: Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice

https://doi.org/10.18632/oncotarget.28532

Fariba Poosti, Ruchi Bansal, Saleh Yazdani, Jai Prakash, Leonie Beljaars, Jacob van den Born, Martin H. de Borst, Harry van Goor, Jan-Luuk Hillebrands,  and Klaas Poelstra
35-35
Retraction  |  PDF  |  How to cite

Research Perspectives

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation

https://doi.org/10.18632/oncotarget.28544

Mark Lee,  and Luc GT Morris
36-48
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

BCAS1 defines a heterogeneous cell population in diffuse gliomas

BCAS1 defines a heterogeneous cell population in diffuse gliomas

https://doi.org/10.18632/oncotarget.28553

Raquel Morales-Gallel, María José Ulloa-Navas, Patricia García-Tárraga, Ricardo Prat-Acín, Gaspar Reynés, Pedro Pérez-Borredá, Luis Rubio, Vivian Capilla-González, Jaime Ferrer-Lozano,  and José Manuel García-Verdugo
49-64
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma

https://doi.org/10.18632/oncotarget.28547

Ashley Del Dosso, Elizabeth Tadevosyan,  and James R. Berenson
65-75
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples

Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples

https://doi.org/10.18632/oncotarget.28554

Chongtham Sovachandra Singh, Nabamita Boruah, Atanu Banerjee, Sillarine Kurkalang, Pooja Swargiary, Hughbert Dakhar,  and Anupam Chatterjee
76-89
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: Long noncoding RNA TUG1 is a diagnostic factor in lung adenocarcinoma and suppresses apoptosis via epigenetic silencing of BAX

Retraction: Long noncoding RNA TUG1 is a diagnostic factor in lung adenocarcinoma and suppresses apoptosis via epigenetic silencing of BAX

https://doi.org/10.18632/oncotarget.28462

Huan Liu, Guizhi Zhou, Xin Fu, Haiyan Cui, Guangrui Pu, Yao Xiao, Wei Sun, Xinhua Dong, Libin Zhang, Sijia Cao, Guiqin Li, Xiaowei Wu,  and Xu Yang
90-90
Retraction  |  PDF  |  How to cite

Research Papers

Genetic and therapeutic landscapes in cohort of pancreatic adenocarcinomas: next-generation sequencing and machine learning for full tumor exome analysis

Genetic and therapeutic landscapes in cohort of pancreatic adenocarcinomas: next-generation sequencing and machine learning for full tumor exome analysis

https://doi.org/10.18632/oncotarget.28512

P.A. Shatalov, N.A. Falaleeva, E.A. Bykova, D.O. Korostin, V.A. Belova, A.A. Zabolotneva, A.P. Shinkarkina, A. Yu Gorbachev, M.B. Potievskiy, V.S. Surkova, Zh V. Khailova, N.A. Kulemin, Denis Baranovskii, A.A. Kostin, A.D. Kaprin,  and P.V. Shegai
91-103
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: Targeting programmed cell death ligand 1 by CRISPR/Cas9 in osteosarcoma cells

Correction: Targeting programmed cell death ligand 1 by CRISPR/Cas9 in osteosarcoma cells

https://doi.org/10.18632/oncotarget.28536

Yunfei Liao, Lulu Chen, Yong Feng, Jacson Shen, Yan Gao, Gregory Cote, Edwin Choy, David Harmon, Henry Mankin, Francis Hornicek,  and Zhenfeng Duan
104-105
Correction  |  PDF  |  How to cite

Research Papers

Neurotrophic-tyrosine receptor kinase gene fusion in papillary thyroid cancer: A clinicogenomic biobank and record linkage study from Finland

Neurotrophic-tyrosine receptor kinase gene fusion in papillary thyroid cancer: A clinicogenomic biobank and record linkage study from Finland

https://doi.org/10.18632/oncotarget.28555

Wei Zhang, Arndt A. Schmitz, Roosa E. Kallionpää, Merja Perälä, Niina Pitkänen, Mikko Tukiainen, Erika Alanne, Korinna Jöhrens, Renate Schulze-Rath, Bahman Farahmand,  and Jihong Zong
106-116
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel

https://doi.org/10.18632/oncotarget.28549

Alberto Moscona-Nissan, Karl J. Habashy, Victor A. Arrieta, Adam M. Sonabend,  and Crismita Dmello
117-122
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1α inhibition, and hypoxia-activated chemotherapy

Retraction: Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1α inhibition, and hypoxia-activated chemotherapy

https://doi.org/10.18632/oncotarget.28560

Changhwan Yoon, Kevin K. Chang, Jun Ho Lee, William D. Tap, Charles P. Hart, M. Celeste Simon,  and Sam S. Yoon
123-123
Retraction  |  PDF  |  How to cite

Research Papers

GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells

GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells

https://doi.org/10.18632/oncotarget.28557

Michael R. Booth, Laurence Booth, Jane L. Roberts, Cameron West,  and Paul Dent
124-133
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health

Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health

https://doi.org/10.18632/oncotarget.28561

Elisabetta De Matteis, Maria Rosaria Tumolo, Paolo Tarantino, Mariangela Ciccarese, Tiziana Grassi, Francesco Bagordo, Maria Rita De Giorgio, Emanuele Rizzo,  and Graziana Ronzino
134-141
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer

Correction: Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer

https://doi.org/10.18632/oncotarget.28523

Maryam Zanjirband, Nicola Curtin, Richard J. Edmondson,  and John Lunec
142-142
Correction  |  PDF  |  How to cite

Corrections

Correction: YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model

Correction: YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model

https://doi.org/10.18632/oncotarget.28524

Tsion Zewdu Minas, Jenny Han, Tahereh Javaheri, Sung-Hyeok Hong, Michaela Schlederer, Yasemin Saygideğer-Kont, Haydar Çelik, Kristina M. Mueller, Idil Temel, Metin Özdemirli, Heinrich Kovar, Hayriye Verda Erkizan, Jeffrey Toretsky, Lukas Kenner, Richard Moriggl,  and Aykut Üren
143-143
Correction  |  PDF  |  How to cite

Research Papers

Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas

Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas

https://doi.org/10.18632/oncotarget.28559

Thomas M. Cardillo, Maria B. Zalath, Roberto Arrojo, Robert M. Sharkey, Serengulam V. Govindan, Chien-Hsing Chang,  and David M. Goldenberg
144-158
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells

GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells

https://doi.org/10.18632/oncotarget.28558

Laurence Booth, Jane L. Roberts, Cameron West,  and Paul Dent
159-174
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

G-quadruplex landscape and its regulation revealed by a new antibody capture method

G-quadruplex landscape and its regulation revealed by a new antibody capture method

https://doi.org/10.18632/oncotarget.28564

Subhamoy Datta, Manthan Patel, Chakkarai Sathyaseelan, Chandrama Ghosh, Akanksha Mudgal, Divyesh Patel, Thenmalarchelvi Rathinavelan,  and Umashankar Singh
175-198
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Corrections

Correction: Sigma-1 and Sigma-2 receptor ligands induce apoptosis and autophagy but have opposite effect on cell proliferation in uveal melanoma

Correction: Sigma-1 and Sigma-2 receptor ligands induce apoptosis and autophagy but have opposite effect on cell proliferation in uveal melanoma

https://doi.org/10.18632/oncotarget.28519

Lucia Longhitano, Carlo Castruccio Castracani, Daniele Tibullo, Roberto Avola, Maria Viola, Giuliano Russo, Orazio Prezzavento, Agostino Marrazzo, Emanuele Amata, Michele Reibaldi, Antonio Longo, Andrea Russo, Nunziatina Laura Parrinello,  and Giovanni Li Volti
199-199
Correction  |  PDF  |  How to cite

Research Papers

Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay

Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay

https://doi.org/10.18632/oncotarget.28565

Josette Northcott, Gabor Bartha, Jason Harris, Conan Li, Fabio C.P. Navarro, Rachel Marty Pyke, Manqing Hong, Qi Zhang, Shuyuan Ma, Tina X. Chen, Janet Lai, Nitin Udar, Juan-Sebastian Saldivar, Erin Ayash, Joshua Anderson, Jiang Li, Tiange Cui, Tu Le, Ruthie Chow, Randy Jerel Velasco, Chris Mallo, Rose Santiago, Robert C. Bruce, Laurie J. Goodman, Yi Chen, Dan Norton, Richard O. Chen,  and John M. Lyle
200-218
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway

Retraction: PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway

https://doi.org/10.18632/oncotarget.28522

Huijun Gao, Bing Sun, Hailu Fu, Xinming Chi, Faming Wang, Xiaoyu Qi, Jun Hu,  and Shujuan Shao
219-219
Retraction  |  PDF  |  How to cite

Research Papers

ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells

ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells

https://doi.org/10.18632/oncotarget.28563

Benigno C. Valdez, Bin Yuan, David Murray, Jeremy L. Ramdial, Uday Popat, Yago Nieto,  and Borje S. Andersson
220-231
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Perspectives

From osimertinib to preemptive combinations

From osimertinib to preemptive combinations

https://doi.org/10.18632/oncotarget.28569

Mikhail V. Blagosklonny
232-237
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer

https://doi.org/10.18632/oncotarget.28567

Haven R. Garber, Sreyashi Basu, Sonali Jindal, Zhong He, Khoi Chu, Akshara Singareeka Raghavendra, Clinton Yam, Lumarie Santiago, Beatriz E. Adrada, Padmanee Sharma, Elizabeth A. Mittendorf,  and Jennifer K. Litton
238-247
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Exploring the role of GHRH antagonist MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia

Exploring the role of GHRH antagonist MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.28579

Simonetta I. Gaumond, Rama Abdin, Joel Costoya, Andrew V. Schally,  and Joaquin J. Jimenez
248-254
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Knockdown of NEAT1 restrained the malignant progression of glioma stem cells by activating microRNA let-7e

Retraction: Knockdown of NEAT1 restrained the malignant progression of glioma stem cells by activating microRNA let-7e

https://doi.org/10.18632/oncotarget.28568

Wei Gong, Jian Zheng, Xiaobai Liu, Jun Ma, Yunhui Liu,  and Yixue Xue
255-255
Retraction  |  PDF  |  How to cite

Research Papers

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface

https://doi.org/10.18632/oncotarget.28578

Takahiro Ohashi, Sayuri Terada, Shinsuke Hiramoto, Yuko Nagata, Hirokazu Suzuki, Hitoshi Miyashita, Tetsuo Sasaki, Yasukatsu Tsukada,  and Keiko Fukushima
256-274
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure

https://doi.org/10.18632/oncotarget.28582

Shengliang Zhang,  and Wafik S. El-Deiry
275-284
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis

Correction: Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis

https://doi.org/10.18632/oncotarget.28528

Dominique Thuringer, Gaetan Jego, Kevin Berthenet, Arlette Hammann, Eric Solary,  and Carmen Garrido
285-287
Correction  |  PDF  |  How to cite

Research Papers

Deep learning-based whole-body PSMA PET/CT attenuation correction utilizing Pix-2-Pix GAN

Deep learning-based whole-body PSMA PET/CT attenuation correction utilizing Pix-2-Pix GAN

https://doi.org/10.18632/oncotarget.28583

Kevin C. Ma, Esther Mena, Liza Lindenberg, Nathan S. Lay, Phillip Eclarinal, Deborah E. Citrin, Peter A. Pinto, Bradford J. Wood, William L. Dahut, James L. Gulley, Ravi A. Madan, Peter L. Choyke, Ismail Baris Turkbey,  and Stephanie A. Harmon
288-300
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: Chronically high level of tgfb1a induction causes both hepatocellular carcinoma and cholangiocarcinoma via a dominant Erk pathway in zebrafish

Retraction: Chronically high level of tgfb1a induction causes both hepatocellular carcinoma and cholangiocarcinoma via a dominant Erk pathway in zebrafish

https://doi.org/10.18632/oncotarget.28570

Chuan Yan, Qiqi Yang, Han-Ming Shen, Jan M. Spitsbergen,  and Zhiyuan Gong
301-301
Retraction  |  PDF  |  How to cite

Research Papers

Cyclin D1 expression in penile cancer

Cyclin D1 expression in penile cancer

https://doi.org/10.18632/oncotarget.28584

Wesliany Everton Duarte, Jaqueline Diniz Pinho, Syomara Pereira da Costa Melo, Denner Rodrigo Diniz Duarte, Juliana Martins da Guia Ribeiro do Carmo, André Salim Khayat, José Ribamar Rodrigues Calixto, Marcos Adriano Garcia Campos, Rita da Graça Carvalhal Frazão Correa, Antonio Machado Alencar Júnior, Antônio Augusto Lima Teixeira-Júnior,  and Gyl Eanes Barros Silva
302-311
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Knockdown of TRIM65 inhibits lung cancer cell proliferation, migration and invasion: A therapeutic target in human lung cancer

Retraction: Knockdown of TRIM65 inhibits lung cancer cell proliferation, migration and invasion: A therapeutic target in human lung cancer

https://doi.org/10.18632/oncotarget.28571

Xiao-Lin Wang, Wei-Ping Shi, Hong-Can Shi, Shi-Chun Lu, Kang Wang, Chao Sun, Jian-Sheng He, Wei-Guo Jin, Xiao-Xia Lv, Hui Zou,  and Yu-Sheng Shu
312-312
Retraction  |  PDF  |  How to cite

Research Papers

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response

https://doi.org/10.18632/oncotarget.28585

Lulzim Shkreta, Johanne Toutant, Aurélie Delannoy, David Durantel, Anna Salvetti, Sophie Ehresmann, Martin Sauvageau, Julien A. Delbrouck, Alice Gravel-Trudeau, Christian Comeau, Caroline Huard, Jasmin Coulombe-Huntington, Mike Tyers, David Grierson, Pierre-Luc Boudreault,  and Benoit Chabot
313-325
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Video Interview

Corrections

Correction: Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1

Correction: Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1

https://doi.org/10.18632/oncotarget.28562

Jun Guo, Weiwei Fang, Libo Sun, Yonggang Lu, Lin Dou, Xiuqing Huang, Mingxiao Sun, Cheng Pang, Jing Qu, Guanghui Liu,  and Jian Li
326-327
Correction  |  PDF  |  How to cite

Research Papers

GZ17-6.02 kills PDX isolates of uveal melanoma

GZ17-6.02 kills PDX isolates of uveal melanoma

https://doi.org/10.18632/oncotarget.28586

Laurence Booth, Jane L. Roberts, Ivan Spasojevic, Kaitlyn C. Baker, Andrew Poklepovic, Cameron West, John M. Kirkwood,  and Paul Dent
328-344
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Reviews

The importance of integrated therapies on cancer: Silibinin, an old and new molecule

The importance of integrated therapies on cancer: Silibinin, an old and new molecule

https://doi.org/10.18632/oncotarget.28587

Elisa Roca, Giuseppe Colloca, Fiorella Lombardo, Andrea Bellieni, Alessandra Cucinella, Giorgio Madonia, Licia Martinelli, Maria Elisa Damiani, Ilaria Zampieri,  and Antonio Santo
345-353
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Acquired resistance to BRAFi reverses senescence-like phenotype in mutant BRAF melanoma

Retraction: Acquired resistance to BRAFi reverses senescence-like phenotype in mutant BRAF melanoma

https://doi.org/10.18632/oncotarget.28580

Mohammad Krayem, Ahmad Najem, Fabrice Journe, Renato Morandini, François Sales, Ahmad Awada,  and Ghanem E. Ghanem
354-354
Retraction  |  PDF  |  How to cite

Research Perspectives

Bruton’s tyrosine kinase inhibitor-related cardiotoxicity: The quest for predictive biomarkers and improved risk stratification

Bruton’s tyrosine kinase inhibitor-related cardiotoxicity: The quest for predictive biomarkers and improved risk stratification

https://doi.org/10.18632/oncotarget.28589

Jai N. Patel, Jai Singh,  and Nilanjan Ghosh
355-359
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Long non-coding RNA H19 induces hippocampal neuronal apoptosis via Wnt signaling in a streptozotocin-induced rat model of diabetes mellitus

Retraction: Long non-coding RNA H19 induces hippocampal neuronal apoptosis via Wnt signaling in a streptozotocin-induced rat model of diabetes mellitus

https://doi.org/10.18632/oncotarget.28576

Yu-Hao Zhao, Tie-Feng Ji, Qi Luo,  and Jin-Lu Yu
360-360
Retraction  |  PDF  |  How to cite

Research Papers

Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy

Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy

https://doi.org/10.18632/oncotarget.28588

Benigno C. Valdez, Apostolia M. Tsimberidou, Bin Yuan, Yago Nieto, Mehmet A. Baysal, Abhijit Chakraborty, Clark R. Andersen,  and Borje S. Andersson
361-373
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

When does a melanoma metastasize? Implications for management

When does a melanoma metastasize? Implications for management

https://doi.org/10.18632/oncotarget.28591

John F. Thompson,  and Gabrielle J. Williams
374-378
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: FOXC1 promotes melanoma by activating MST1R/PI3K/AKT pathway and is associated with poor prognosis in melanoma

Correction: FOXC1 promotes melanoma by activating MST1R/PI3K/AKT pathway and is associated with poor prognosis in melanoma

https://doi.org/10.18632/oncotarget.28590

Jinhua Wang, Li Li, Shiwei Liu, Ying Zhao, Lin Wang,  and Guanhua Du
379-380
Correction  |  PDF  |  How to cite

Research Papers

Assessment of serum tumor markers CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management

Assessment of serum tumor markers CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management

https://doi.org/10.18632/oncotarget.28566

Scott Strum, Mark Vincent, Meghan Gipson, Eric McArthur,  and Daniel Breadner
381-388
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Leveraging gold nanostars for precision laser interstitial thermal therapy

Leveraging gold nanostars for precision laser interstitial thermal therapy

https://doi.org/10.18632/oncotarget.28592

Aden P. Haskell-Mendoza, Ethan S. Srinivasan, Tuan Vo-Dinh,  and Peter E. Fecci
389-391
PDF  |  How to cite  |  Press Release

Research Perspectives

Starving cancer cells to enhance DNA damage and immunotherapy response

Starving cancer cells to enhance DNA damage and immunotherapy response

https://doi.org/10.18632/oncotarget.28595

Aashirwad Shahi,  and Dawit Kidane
392-399
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Genomics has more to reveal

Genomics has more to reveal

https://doi.org/10.18632/oncotarget.28596

Laurène Fenwarth,  and Nicolas Duployez
400-401
PDF  |  How to cite

Retraction

Retraction: Hypoxia-inducible factor 1a induces phenotype switch of human aortic vascular smooth muscle cell through PI3K/AKT/AEG-1 signaling

Retraction: Hypoxia-inducible factor 1a induces phenotype switch of human aortic vascular smooth muscle cell through PI3K/AKT/AEG-1 signaling

https://doi.org/10.18632/oncotarget.28575

Kai Liu, Changcun Fang, Yuwen Shen, Zhengqin Liu, Min Zhang, Bingbing Ma,  and Xinyan Pang
402-402
Retraction  |  PDF  |  How to cite

Editorial

Targeting ABC transporters in PDAC – past, present, or future?

Targeting ABC transporters in PDAC – past, present, or future?

https://doi.org/10.18632/oncotarget.28597

Cecilia Bergonzini, Elisa Giovannetti,  and Erik H.J. Danen
403-406
PDF  |  How to cite

Corrections

Correction: Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay

Correction: Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay

https://doi.org/10.18632/oncotarget.28581

Josette Northcott, Gabor Bartha, Jason Harris, Conan Li, Fabio C.P. Navarro, Rachel Marty Pyke, Manqing Hong, Qi Zhang, Shuyuan Ma, Tina X. Chen, Janet Lai, Nitin Udar, Juan-Sebastian Saldivar, Erin Ayash, Joshua Anderson, Jiang Li, Tiange Cui, Tu Le, Ruthie Chow, Randy Jerel Velasco, Chris Mallo, Rose Santiago, Robert C. Bruce, Laurie J. Goodman, Yi Chen, Dan Norton, Richard O. Chen,  and John M. Lyle
407-407
Correction  |  PDF  |  How to cite

Research Papers

Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma

Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma

https://doi.org/10.18632/oncotarget.28594

Kazuhiro Kitajima, Kozo Kuribayashi, Toshiyuki Minami, Hiroyuki Yokoyama, Akifumi Nakamura, Masaki Hashimoto, Takashi Kijima, Seiki Hasegawa, Hayato Kaida,  and Koichiro Yamakado
408-417
Abstract  |  PDF  |  Full Text  |  How to cite

Editorial

HER2-low and HER2-zero in breast cancer between prognosis, prediction and entity

HER2-low and HER2-zero in breast cancer between prognosis, prediction and entity

https://doi.org/10.18632/oncotarget.28598

Marcus Schmidt, Hans-Anton Lehr,  and Katrin Almstedt
418-420
PDF  |  How to cite


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