Oncotarget

Volume 14 (2023)

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About The Cover

The cover for Oncotarget's Volume 14 (2023) features Figure 1C, from "Inhibiting BRAF/EGFR/MEK suppresses cancer stemness and drug resistance of primary colorectal cancer cells" by Lamichhane, et al.

Table of Contents

Research Papers

Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001

Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001

https://doi.org/10.18632/oncotarget.28341

Xiaofan Li, Cristina Abrahams, Abigail Yu, Millicent Embry, Robert Henningsen, Venita DeAlmeida, Shannon Matheny, Toni Kline, Alice Yam, Ryan Stafford, Trevor Hallam, Mark Lupher,  and Arturo Molina
1-13
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels

Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels

https://doi.org/10.18632/oncotarget.28342

Christina Kuhn, Myriam Boeschen, Manuel Philip, Torsten Schöneberg, Doreen Thor,  and Susanne Horn
14-20
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Corrections

Correction: MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma

Correction: MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma

https://doi.org/10.18632/oncotarget.28336

David King, Xiao Dun Li, Gilberto S. Almeida, Colin Kwok, Polly Gravells, Daniel Harrison, Saoirse Burke, Albert Hallsworth, Yann Jamin, Sally George, Simon P. Robinson, Christopher J. Lord, Evon Poon, Daniel Yeomanson, Louis Chesler,  and Helen E. Bryant
21-22
Correction  |  PDF  |  How to cite

Research Papers

The chromatographic constitution of andiroba oil and its healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option

The chromatographic constitution of andiroba oil and its healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option

https://doi.org/10.18632/oncotarget.28338

Jessica T. Gomes, Ana Márcia V. Wanzeler, Sergio M.A. Júnior, Rosa Helena F. Chaves Soares, Carolina P. de Oliveira, Emanuelle de M. Rodrigues, Bruno M. Soares, Diego D.F.A. Alcantara, Rommel M.R. Burbano,  and Fabrício M. Tuji
23-39
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Perspectives

Intraventricular immunovirotherapy; a translational step forward

Intraventricular immunovirotherapy; a translational step forward

https://doi.org/10.18632/oncotarget.28343

Joshua D. Bernstock, Sarah Blitz, Kyung-Don Kang,  and Gregory K. Friedman
40-43
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells

Correction: IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells

https://doi.org/10.18632/oncotarget.28344

Rehanna Mansor, Jeff Holly, Rachel Barker, Kalina Biernacka, Hanna Zielinska, Anthony Koupparis, Edward Rowe, Jon Oxley, Alex Sewell, Richard M. Martin, Athene Lane, Lucy Hackshaw-McGeagh,  and Claire Perks
44-46
Correction  |  PDF  |  How to cite

Editorial

To be or not to be: the role of CD56 in multiple myeloma

To be or not to be: the role of CD56 in multiple myeloma

https://doi.org/10.18632/oncotarget.28350

Francesca Cottini,  and Don Benson
47-49
PDF  |  How to cite

Retraction

Retraction: Hsa-miR-139-5p inhibits proliferation and causes apoptosis associated with down-regulation of c-Met

Retraction: Hsa-miR-139-5p inhibits proliferation and causes apoptosis associated with down-regulation of c-Met

https://doi.org/10.18632/oncotarget.28329

Chengcao Sun, Ming Sang, Shujun Li, Xiaodong Sun, Cuili Yang, Yongyong Xi, Liang Wang, Feng Zhang, Yongyi Bi, Yunfeng Fu,  and Dejia Li
50-50
Retraction  |  PDF  |  How to cite

Editorial

Permeability and driving force: why is it difficult to control glycolytic flux by blocking lactate transporters?

Permeability and driving force: why is it difficult to control glycolytic flux by blocking lactate transporters?

https://doi.org/10.18632/oncotarget.28351

Wiktoria Blaszczak,  and Pawel Swietach
51-52
PDF  |  How to cite

Corrections

Correction: Synergistic antitumor activity by combining trastuzumab with retinoic acid in HER2 positive human breast cancer cells

Correction: Synergistic antitumor activity by combining trastuzumab with retinoic acid in HER2 positive human breast cancer cells

https://doi.org/10.18632/oncotarget.28345

Fiorella Vanderhoeven, Analía Lourdes Redondo, Ana Laura Martinez, Laura María Vargas-Roig, Angel Matias Sanchez,  and Marina Inés Flamini
53-53
Correction  |  PDF  |  How to cite

Editorial

The role of Kras and canonical Wnt pathways for tumorigenesis of extrahepatic biliary system

The role of Kras and canonical Wnt pathways for tumorigenesis of extrahepatic biliary system

https://doi.org/10.18632/oncotarget.28349

Munemasa Nagao, Akihisa Fukuda,  and Hiroshi Seno
54-56
PDF  |  How to cite

Research Papers

Spleen tyrosine kinase/FMS-like tyrosine kinase-3 inhibition in relapsed/refractory B-cell lymphoma, including diffuse large B-cell lymphoma: updated data with mivavotinib (TAK-659/CB-659)

Spleen tyrosine kinase/FMS-like tyrosine kinase-3 inhibition in relapsed/refractory B-cell lymphoma, including diffuse large B-cell lymphoma: updated data with mivavotinib (TAK-659/CB-659)

https://doi.org/10.18632/oncotarget.28352

Leo I. Gordon, Reem Karmali, Jason B. Kaplan, Rakesh Popat, Howard A. Burris III, Silvia Ferrari, Sumit Madan, Manish R. Patel, Giuseppe Gritti, Dima El-Sharkawi, F. Ian Chau, John Radford, Jaime Pérez de Oteyza, Pier Luigi Zinzani, Swaminathan P. Iyer, William Townsend, Harry Miao, Igor Proscurshim, Shining Wang, Shilpi Katyayan, Ying Yuan, Jiaxi Zhu, Kate Stumpo, Yaping Shou, Cecilia Carpio,  and Francesc Bosch
57-70
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Novel inflammation-combined prognostic index to predict survival outcomes in patients with gastric cancer

Novel inflammation-combined prognostic index to predict survival outcomes in patients with gastric cancer

https://doi.org/10.18632/oncotarget.28353

Noriyuki Hirahara, Takeshi Matsubara, Shunsuke Kaji, Hikota Hayashi, Yohei Sasaki, Koki Kawakami, Ryoji Hyakudomi, Tetsu Yamamoto,  and Yoshitsugu Tajima
71-82
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6

Correction: Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6

https://doi.org/10.18632/oncotarget.28115

Nicole Golob-Schwarzl, Caroline Schweiger, Carina Koller, Stefanie Krassnig, Margit Gogg-Kamerer, Nadine Gantenbein, Anna M. Toeglhofer, Christina Wodlej, Helmut Bergler, Brigitte Pertschy, Stefan Uranitsch, Magdalena Holter, Amin El-Heliebi, Julia Fuchs, Andreas Punschart, Philipp Stiegler, Marlen Keil, Jens Hoffmann, David Henderson, Hans Lehrach, Christoph Reinhard, Christian Regenbrecht, Rudolf Schicho, Peter Fickert, Sigurd Lax,  and Johannes Haybaeck
83-84
Correction  |  PDF  |  How to cite

Research Papers

Everolimus downregulates STAT3/HIF-1α/VEGF pathway to inhibit angiogenesis and lymphangiogenesis in TP53 mutant head and neck squamous cell carcinoma (HNSCC)

Everolimus downregulates STAT3/HIF-1α/VEGF pathway to inhibit angiogenesis and lymphangiogenesis in TP53 mutant head and neck squamous cell carcinoma (HNSCC)

https://doi.org/10.18632/oncotarget.28355

Md Maksudul Alam, Janmaris Marin Fermin, Mark Knackstedt, Mackenzie J. Noonan, Taylor Powell, Landon Goodreau, Emily K. Daniel, Xiaohua Rong, Tara Moore-Medlin, Alok R. Khandelwal,  and Cherie-Ann O. Nathan
85-95
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

The immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

The immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

https://doi.org/10.18632/oncotarget.28354

Anqi Shao,  and David M. Owens
96-103
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer

Correction: KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer

https://doi.org/10.18632/oncotarget.28361

Keisuke Taniuchi,  and Mitsunari Ogasawara
104-104
Correction  |  PDF  |  How to cite

Research Perspectives

WNT-pathway medulloblastoma: what constitutes low-risk and how low can one go?

WNT-pathway medulloblastoma: what constitutes low-risk and how low can one go?

https://doi.org/10.18632/oncotarget.28360

Shakthivel Mani, Abhishek Chatterjee, Archya Dasgupta, Neelam Shirsat, Sridhar Epari, Girish Chinnaswamy,  and Tejpal Gupta
105-110
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

The “extreme phenotype approach” applied to male breast cancer allows the identification of rare variants of ATR as potential breast cancer susceptibility alleles

The “extreme phenotype approach” applied to male breast cancer allows the identification of rare variants of ATR as potential breast cancer susceptibility alleles

https://doi.org/10.18632/oncotarget.28358

Martin Chevarin, Diana Alcantara, Juliette Albuisson, Marie-Agnès Collonge-Rame, Céline Populaire, Zohair Selmani, Amandine Baurand, Caroline Sawka, Geoffrey Bertolone, Patrick Callier, Yannis Duffourd, Philippe Jonveaux, Yves-Jean Bignon, Isabelle Coupier, François Cornelis, Christophe Cordier, Monique Mozelle-Nivoix, Jean-Baptiste Rivière, Paul Kuentz, Christel Thauvin, Romain Boidot, François Ghiringhelli, Marc O'Driscoll, Laurence Faivre,  and Sophie Nambot
111-125
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Addendum

Addendum: Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation

Addendum: Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation

https://doi.org/10.18632/oncotarget.28365

Karam Khaddour, Joshua Dowling, Jiayi Huang, Martha Council, David Chen, Lynn Cornelius, Tanner Johanns, Sonika Dahiya,  and George Ansstas
126-126
Addendum  |  PDF  |  How to cite

Editorial

Unveiling the non-canonical functions of EZH2 in prostate cancer

Unveiling the non-canonical functions of EZH2 in prostate cancer

https://doi.org/10.18632/oncotarget.28357

Yang Yi, Yanqiang Li, Kaifu Chen,  and Qi Cao
127-128
PDF  |  How to cite  |  Press Release

Corrections

Correction: Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma

Correction: Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma

https://doi.org/10.18632/oncotarget.28346

Barbara Marengo, Elda Meta, Chiara Brullo, Chiara De Ciucis, Renata Colla, Andrea Speciale, Ombretta Garbarino, Olga Bruno,  and Cinzia Domenicotti
129-130
Correction  |  PDF  |  How to cite

Addendum

Addendum: Prognostic significance of isochromosome 17q in hematologic malignancies

Addendum: Prognostic significance of isochromosome 17q in hematologic malignancies

https://doi.org/10.18632/oncotarget.28295

Dorota Koczkodaj, Justyna Muzyka-Kasietczuk, Sylwia Chocholska,  and Monika Podhorecka
131-131
Addendum  |  PDF  |  How to cite

Editorial

Unlocking the potential of molecular-driven stratification for osteosarcoma treatment and prognosis

Unlocking the potential of molecular-driven stratification for osteosarcoma treatment and prognosis

https://doi.org/10.18632/oncotarget.28364

Gaël Moquin-Beaudry, Maria Eugenia Marques da Costa, Nathalie Gaspar,  and Antonin Marchais
132-132
PDF  |  How to cite  |  Press Release

Research Papers

Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability

Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability

https://doi.org/10.18632/oncotarget.28359

Clark G. Wang, Malalage N. Peiris, April N. Meyer, Katelyn N. Nelson,  and Daniel J. Donoghue
133-145
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial Perspective

Leakage? or Secretion? unconventional protein secretion in cancer

Leakage? or Secretion? unconventional protein secretion in cancer

https://doi.org/10.18632/oncotarget.28368

Kohji Yamada,  and Kiyotsugu Yoshida
146-147
PDF  |  How to cite

Corrections

Correction: Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells

Correction: Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells

https://doi.org/10.18632/oncotarget.28251

Suthakar Ganapathy, Bo Peng, Ling Shen, Tianqi Yu, Jean Lafontant, Ping Li, Rui Xiong, Alexandros Makriyannis,  and Changyan Chen
148-148
Correction  |  PDF  |  How to cite

Addendum

Addendum: Melatonin increases overall survival of prostate cancer patients with poor prognosis after combined hormone radiation treatment

Addendum: Melatonin increases overall survival of prostate cancer patients with poor prognosis after combined hormone radiation treatment

https://doi.org/10.18632/oncotarget.28363

Gennady M. Zharinov, Oleg A. Bogomolov, Irina V. Chepurnaya, Natalia Yu. Neklasova,  and Vladimir N. Anisimov
149-149
Addendum  |  PDF  |  How to cite

Editorial

Mitochondria engage the integrated stress response to promote tumor growth

Mitochondria engage the integrated stress response to promote tumor growth

https://doi.org/10.18632/oncotarget.28372

Dillon P. Boulton,  and M. Cecilia Caino
150-152
PDF  |  How to cite  |  Press Release

Reviews

What is hemoglobin, albumin, lymphocyte, platelet (HALP) score? A comprehensive literature review of HALP’s prognostic ability in different cancer types

What is hemoglobin, albumin, lymphocyte, platelet (HALP) score? A comprehensive literature review of HALP’s prognostic ability in different cancer types

https://doi.org/10.18632/oncotarget.28367

Christian Mark Farag, Ryan Antar, Sinan Akosman, Matthew Ng,  and Michael J. Whalen
153-172
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Methylation-induced downregulation and tumor suppressive role of microRNA-29b in gastric cancer through targeting LASP1

Retraction: Methylation-induced downregulation and tumor suppressive role of microRNA-29b in gastric cancer through targeting LASP1

https://doi.org/10.18632/oncotarget.28381

Hui Li, Guoqing Liu, Ke Pan, Xiongying Miao,  and Yong Xie
173-173
Retraction  |  PDF  |  How to cite

Editorial Perspective

C/EBPβ cooperates with MYB to maintain the oncogenic program of AML cells

C/EBPβ cooperates with MYB to maintain the oncogenic program of AML cells

https://doi.org/10.18632/oncotarget.28377

Karl-Heinz Klempnauer
174-177
PDF  |  How to cite  |  Press Release

Research Papers

Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss

Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss

https://doi.org/10.18632/oncotarget.28376

Maroun Bou Zerdan, Prashanth Ashok Kumar, Elio Haroun, Nimisha Srivastava, Jeffrey Ross,  and Abirami Sivapiragasam
178-187
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Corrections

Correction: UBE2T knockdown inhibits gastric cancer progression

Correction: UBE2T knockdown inhibits gastric cancer progression

https://doi.org/10.18632/oncotarget.28356

Changjiang Luo, Yunyi Yao, Zeyuan Yu, Huinian Zhou, Lingyun Guo, Junqiang Zhang, Hongtai Cao, Genyuan Zhang, Yumin Li,  and Zuoyi Jiao
188-189
Correction  |  PDF  |  How to cite

Editorial

Proof-of-principle: targeted childhood leukemia prevention

Proof-of-principle: targeted childhood leukemia prevention

https://doi.org/10.18632/oncotarget.28371

César Cobaleda, Manuel Ramírez-Orellana, Carolina Vicente-Dueñas, Andreas Weiss, Kim E. Nichols,  and Isidro Sánchez-García
190-192
PDF  |  How to cite

Reviews

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

https://doi.org/10.18632/oncotarget.28382

Mikhail V. Blagosklonny
193-206
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Impact of cortactin in cancer progression on Wnt5a/ROR1 signaling pathway

Impact of cortactin in cancer progression on Wnt5a/ROR1 signaling pathway

https://doi.org/10.18632/oncotarget.28386

Kamrul Hasan,  and Thomas J. Kipps
207-209
PDF  |  How to cite  |  Press Release

Corrections

Correction: Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma

Correction: Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma

https://doi.org/10.18632/oncotarget.28347

Yonghao Zhan, Yifan Li, Bao Guan, Xiaoying Chen, Zhicong Chen, Anbang He, Shiming He, Yanqing Gong, Ding Peng, Yuchen Liu, Zhiming Cai, Xuesong Li,  and Liqun Zhou
210-210
Correction  |  PDF  |  How to cite

Editorial Perspective

Cancer-associated fibroblasts: challenges and opportunities

Cancer-associated fibroblasts: challenges and opportunities

https://doi.org/10.18632/oncotarget.28385

Hossein Tavana,  and Gary D. Luker
211-214
PDF  |  How to cite  |  Press Release

Corrections

Correction: Annexin A13 promotes tumor cell invasion in vitro and is associated with metastasis in human colorectal cancer

Correction: Annexin A13 promotes tumor cell invasion in vitro and is associated with metastasis in human colorectal cancer

https://doi.org/10.18632/oncotarget.28247

Guozhong Jiang, Pengju Wang, Weiwei Wang, Wencai Li, Liping Dai,  and Kuisheng Chen
215-215
Correction  |  PDF  |  How to cite

Editorial

Therapy drives genomic evolution in metastatic cancer

Therapy drives genomic evolution in metastatic cancer

https://doi.org/10.18632/oncotarget.28379

Ditte S. Christensen,  and Nicolai J. Birkbak
216-218
PDF  |  How to cite

Research Papers

Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior

Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior

https://doi.org/10.18632/oncotarget.28388

Fang Cheng, Victor Chérouvrier Hansson, Grigorios Georgolopoulos,  and Katrin Mani
219-235
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial Perspective

Genetic modifiers of p53: opportunities for breast cancer therapies

Genetic modifiers of p53: opportunities for breast cancer therapies

https://doi.org/10.18632/oncotarget.28387

Prabin Dhangada Majhi, Aman Sharma,  and D. Joseph Jerry
236-241
PDF  |  How to cite  |  Press Release

Retraction

Retraction: Overexpression of NR4A1 is associated with tumor recurrence and poor survival in non-small-cell lung carcinoma

Retraction: Overexpression of NR4A1 is associated with tumor recurrence and poor survival in non-small-cell lung carcinoma

https://doi.org/10.18632/oncotarget.28396

Bing Zhu, Jian-Ru Yang, Yang Jia, Pei Zhang, Lin Shen, Xiao-Long Li, Jing Li,  and Bing Wang
242-242
Retraction  |  PDF  |  How to cite

Research Papers

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines

https://doi.org/10.18632/oncotarget.28390

Nada Tawfeeq, Jassy Mary S. Lazarte, Yonghao Jin, Matthew D. Gregory,  and Nazarius S. Lamango
243-257
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

Neutrophil PAD4: how does it function in cancer beyond promoting NETosis?

Neutrophil PAD4: how does it function in cancer beyond promoting NETosis?

https://doi.org/10.18632/oncotarget.28369

Laura Garcia-Gerique,  and Yulia Nefedova
258-260
PDF  |  How to cite  |  Press Release

Research Papers

Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells

Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells

https://doi.org/10.18632/oncotarget.27728

Wataru Arai, Takumi Konno, Takayuki Kohno, Yuki Kodera, Mitsuhiro Tsujiwaki, Yuma Shindo, Hirofumi Chiba, Masahiro Miyajima, Yuji Sakuma, Atsushi Watanabe,  and Takashi Kojima
261-275
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

p53 protects against formation of extrahepatic biliary precancerous lesions in the context of oncogenic Kras

p53 protects against formation of extrahepatic biliary precancerous lesions in the context of oncogenic Kras

https://doi.org/10.18632/oncotarget.28380

Munemasa Nagao, Kenta Mizukoshi, Shinnosuke Nakayama, Mio Namikawa, Yukiko Hiramatsu, Takahisa Maruno, Yuki Nakanishi, Tatsuaki Tsuruyama, Akihisa Fukuda,  and Hiroshi Seno
276-279
PDF  |  How to cite

Corrections

Correction: YB-1 regulates tumor growth by promoting MACC1/c-Met pathway in human lung adenocarcinoma

Correction: YB-1 regulates tumor growth by promoting MACC1/c-Met pathway in human lung adenocarcinoma

https://doi.org/10.18632/oncotarget.28393

Tao Guo, Shilei Zhao, Peng Wang, Xiaoyuan Xue, Yan Zhang, Mengying Yang, Nan Li, Zhuoshi Li, Lingzhi Xu, Lei Jiang, Lei Zhao, Patrick C. Ma, Rafael Rosell, Jinxiu Li,  and Chundong Gu
280-280
Correction  |  PDF  |  How to cite

Editorial

Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors

Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors

https://doi.org/10.18632/oncotarget.28392

Giulia Franciosa,  and Jesper V. Olsen
281-283
PDF  |  How to cite  |  Press Release

Reviews

Crosstalk between triple negative breast cancer and microenvironment

Crosstalk between triple negative breast cancer and microenvironment

https://doi.org/10.18632/oncotarget.28397

Karly Smrekar, Artem Belyakov,  and Kideok Jin
284-293
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Retraction

Retraction: Significance of B10 cell in patients with thymoma complicated with myasthenia gravis

Retraction: Significance of B10 cell in patients with thymoma complicated with myasthenia gravis

https://doi.org/10.18632/oncotarget.28160

Yang Lu, Fanjie Meng, Yang Yang, Lan Li, Donghao Wang, Yuantao Cui, Shangwen Dong,  and Wanhua Wang
294-294
Retraction  |  PDF  |  How to cite

Editorial

Tumor necroptosis promotes metastasis through modulating the interplay between tumor and host immunity

Tumor necroptosis promotes metastasis through modulating the interplay between tumor and host immunity

https://doi.org/10.18632/oncotarget.28404

Zhaoshan Liu, Swati Choksi,  and Zheng-Gang Liu
295-296
PDF  |  How to cite  |  Press Release

Editorial Perspective

EGFR endocytosis: more than meets the eye

EGFR endocytosis: more than meets the eye

https://doi.org/10.18632/oncotarget.28400

Aysegul Sapmaz,  and Ayse Elif Erson-Bensan
297-301
PDF  |  How to cite

Research Papers

A phase I trial of riluzole and sorafenib in patients with advanced solid tumors: CTEP #8850

A phase I trial of riluzole and sorafenib in patients with advanced solid tumors: CTEP #8850

https://doi.org/10.18632/oncotarget.28403

Kristen R. Spencer, Daniella E. Portal, Joseph Aisner, Mark N. Stein, Jyoti Malhotra, Weichung Shih, Nancy Chan, Ann W. Silk, Shridar Ganesan, Susan Goodin, Murugesan Gounder, Hongxia Lin, Jiadong Li, Robert Cerchio, Christina Marinaro, Suzie Chen,  and Janice M. Mehnert
302-315
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Corrections

Correction: Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis

Correction: Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis

https://doi.org/10.18632/oncotarget.28394

Ajay Kale, Afaf Aldahish,  and Girish Shah
316-316
Correction  |  PDF  |  How to cite

Editorial

The nuclear envelope and metastasis

The nuclear envelope and metastasis

https://doi.org/10.18632/oncotarget.28375

Emily Hansen,  and James M. Holaska
317-320
PDF  |  How to cite  |  Press Release

Research Perspectives

Adopted neoplastic cells and the consequences of their existence

Adopted neoplastic cells and the consequences of their existence

https://doi.org/10.18632/oncotarget.28408

Yuri Lazebnik
321-341
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Perspectives

Cancer prevention with rapamycin

Cancer prevention with rapamycin

https://doi.org/10.18632/oncotarget.28410

Mikhail V. Blagosklonny
342-350
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

Importance of carbohydrate antigen (CA 19-9) and carcinoembrionic antigen (CEA) in the prognosis of patients with duodenal adenocarcinoma: a retrospective single-institution cohort study

Importance of carbohydrate antigen (CA 19-9) and carcinoembrionic antigen (CEA) in the prognosis of patients with duodenal adenocarcinoma: a retrospective single-institution cohort study

https://doi.org/10.18632/oncotarget.28406

Ellery Altshuler, Raymond Richhart, William King, Mahmoud Aryan, Akash Mathavan, Akshay Mathavan, Keegan Hones, Daniel F. Leach III, Logan Pucci, Joshua Riklan, Pat Haley, Ilyas Sahin, Brian Ramnaraign, Sherise Rogers, Ibrahim Nassour, Steven Hughes, Thomas J. George,  and Jesus Fabregas
351-357
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Perspectives

Crossroads: the role of biomarkers in the management of lumps in the breast

Crossroads: the role of biomarkers in the management of lumps in the breast

https://doi.org/10.18632/oncotarget.28402

Georg F. Weber
358-362
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Video Interview

Retraction

Retraction: LncRNA NEAT1 enhances the radio-resistance of cervical cancer via miR-193b-3p/CCND1 axis

Retraction: LncRNA NEAT1 enhances the radio-resistance of cervical cancer via miR-193b-3p/CCND1 axis

https://doi.org/10.18632/oncotarget.28416

Dongmei Han, Jianfeng Wang,  and Guanghui Cheng
363-363
Retraction  |  PDF  |  How to cite

Editorial

The critical immune basis for differential responses to immunotherapy in primary versus metastatic pancreatic cancer

The critical immune basis for differential responses to immunotherapy in primary versus metastatic pancreatic cancer

https://doi.org/10.18632/oncotarget.28373

Brian Diskin, Sarah Schwartz,  and George Miller
364-365
PDF  |  How to cite

Research Papers

Differential silencing of STAT3 isoforms leads to changes in STAT3 activation

Differential silencing of STAT3 isoforms leads to changes in STAT3 activation

https://doi.org/10.18632/oncotarget.28412

Inbal Shamir, Ilan Tsarfaty, Gidi Paret,  and Yael Nevo-Caspi
366-376
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Perspectives

Disruption of retinol-mediated IL-6 expression in colon cancer-associated fibroblasts: new perspectives on the role of vitamin A metabolism

Disruption of retinol-mediated IL-6 expression in colon cancer-associated fibroblasts: new perspectives on the role of vitamin A metabolism

https://doi.org/10.18632/oncotarget.28399

Romain Villéger, Marina Chulkina, Randy C. Mifflin, Don W. Powell,  and Irina V. Pinchuk
377-381
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

A balancing act: how whole-genome doubling and aneuploidy interact in human cancer

A balancing act: how whole-genome doubling and aneuploidy interact in human cancer

https://doi.org/10.18632/oncotarget.28374

Kavya Prasad,  and Uri Ben-David
382-383
PDF  |  How to cite

Reviews

Systemic AL amyloidosis: current approach and future direction

Systemic AL amyloidosis: current approach and future direction

https://doi.org/10.18632/oncotarget.28415

Maroun Bou Zerdan, Lewis Nasr, Farhan Khalid, Sabine Allam, Youssef Bouferraa, Saba Batool, Muhammad Tayyeb, Shubham Adroja, Mahinbanu Mammadii, Faiz Anwer, Shahzad Raza,  and Chakra P. Chaulagain
384-394
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

AGO2 in T-prolymphocytic leukemia: its canonical and non-canonical deregulation and function

AGO2 in T-prolymphocytic leukemia: its canonical and non-canonical deregulation and function

https://doi.org/10.18632/oncotarget.28378

Till Braun, Hanna Klepzig,  and Marco Herling
395-397
PDF  |  How to cite  |  Press Release

Retraction

Retraction: Overexpression of microRNA-132 enhances the radiosensitivity of cervical cancer cells by down-regulating Bmi-1

Retraction: Overexpression of microRNA-132 enhances the radiosensitivity of cervical cancer cells by down-regulating Bmi-1

https://doi.org/10.18632/oncotarget.28413

Gui-Feng Liu, Shu-Hua Zhang, Xue-Feng Li, Li-Yan Cao, Zhan-Zhao Fu,  and Shao-Nan Yu
398-398
Retraction  |  PDF  |  How to cite

Research Perspectives

Using cancer proteomics data to identify gene candidates for therapeutic targeting

Using cancer proteomics data to identify gene candidates for therapeutic targeting

https://doi.org/10.18632/oncotarget.28420

Diana Monsivais, Sydney E. Parks, Darshan S. Chandrashekar, Sooryanarayana Varambally,  and Chad J. Creighton
399-412
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

From the groin to the brain: a transfemoral path to blood-brain barrier opening

From the groin to the brain: a transfemoral path to blood-brain barrier opening

https://doi.org/10.18632/oncotarget.28414

Thomas C. Chen, Weijun Wang,  and Axel H. Schönthal
413-416
PDF  |  How to cite

Corrections

Correction: Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration

Correction: Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration

https://doi.org/10.18632/oncotarget.28411

Ao Zhang, Masahiro Hitomi, Noah Bar-Shain, Zafardjan Dalimov, Leigh Ellis, Kiran K. Velpula, Gail C. Fraizer, Robert G. Gourdie,  and Justin D. Lathia
417-418
Correction  |  PDF  |  How to cite

Research Perspectives

Targeting cellular respiration as a therapeutic strategy in glioblastoma

Targeting cellular respiration as a therapeutic strategy in glioblastoma

https://doi.org/10.18632/oncotarget.28424

Enyuan Shang, Trang Thi Thu Nguyen, Mike-Andrew Westhoff, Georg Karpel-Massler,  and Markus D. Siegelin
419-425
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

Human LY6 gene family: potential tumor-associated antigens and biomarkers of prognosis in uterine corpus endometrial carcinoma

Human LY6 gene family: potential tumor-associated antigens and biomarkers of prognosis in uterine corpus endometrial carcinoma

https://doi.org/10.18632/oncotarget.28409

Luke A. Rathbun, Anthony M. Magliocco,  and Anil K. Bamezai
426-437
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Addendum

Addendum: Newly diagnosed papillary craniopharyngioma with BRAF V600E mutation treated with single-agent selective BRAF inhibitor dabrafenib: a case report

Addendum: Newly diagnosed papillary craniopharyngioma with BRAF V600E mutation treated with single-agent selective BRAF inhibitor dabrafenib: a case report

https://doi.org/10.18632/oncotarget.28428

Mayank Rao, Meenakshi Bhattacharjee, Scott Shepard,  and Sigmund Hsu
438-438
Addendum  |  PDF  |  How to cite

Research Perspectives

HER3- A key survival pathway and an emerging therapeutic target in metastatic colorectal cancer and pancreatic ductal adenocarcinoma

HER3- A key survival pathway and an emerging therapeutic target in metastatic colorectal cancer and pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.28421

Omkar Desai,  and Rui Wang
439-443
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Video Interview

Editorial

Targeting H3K27me3 loss in pediatric brain tumors - a perspective on epigenetically guided cancer therapy

Targeting H3K27me3 loss in pediatric brain tumors - a perspective on epigenetically guided cancer therapy

https://doi.org/10.18632/oncotarget.28427

Michael Goldstein
444-447
PDF  |  How to cite  |  Press Release

Corrections

Correction: A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling

Correction: A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling

https://doi.org/10.18632/oncotarget.28430

Stephan J. Matissek, Mona Karbalivand, Weiguo Han, Ava Boutilier, Estefania Yzar-Garcia, Laura L. Kehoe, Devin Storm Gardner, Adam Hage, Krista Fleck, Vicki Jeffers, Ricardo Rajsbaum,  and Sherine F. Elsawa
448-448
Correction  |  PDF  |  How to cite

Addendum

Addendum: Histological and molecular analysis of a progressive diffuse intrinsic pontine glioma and synchronous metastatic lesions: a case report

Addendum: Histological and molecular analysis of a progressive diffuse intrinsic pontine glioma and synchronous metastatic lesions: a case report

https://doi.org/10.18632/oncotarget.28286

Javad Nazarian, Gary E. Mason, Cheng Ying Ho, Eshini Panditharatna, Madhuri Kambhampati, L. Gilbert Vezina, Roger J. Packer,  and Eugene I. Hwang
449-449
Addendum  |  PDF  |  How to cite

Research Papers

Development and implementation of an automated and highly accurate reporting process for NGS-based clonality testing

Development and implementation of an automated and highly accurate reporting process for NGS-based clonality testing

https://doi.org/10.18632/oncotarget.28429

Sean T. Glenn, Phillip M. Galbo Jr., Jesse D. Luce, Kiersten Marie Miles, Prashant K. Singh, Manuel J. Glynias,  and Carl Morrison
450-461
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

The molecular dialogue between the tumor cells and fibroblasts

The molecular dialogue between the tumor cells and fibroblasts

https://doi.org/10.18632/oncotarget.28405

Ramesh Butti,  and Gopal C. Kundu
462-463
PDF  |  How to cite  |  Video Interview

Corrections

Correction: miR-29a-3p suppresses cell proliferation and migration by downregulating IGF1R in hepatocellular carcinoma

Correction: miR-29a-3p suppresses cell proliferation and migration by downregulating IGF1R in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.28398

Xiao Wang, Shasha Liu, Ling Cao, Tengfei Zhang, Dongli Yue, Liping Wang, Yu Ping, Qianyi He, Chaoqi Zhang, Meng Wang, Xinfeng Chen, Qun Gao, Dan Wang, Zhen Zhang, Fei Wang, Li Yang, Jieyao Li, Lan Huang, Bin Zhang,  and Yi Zhang
464-465
Correction  |  PDF  |  How to cite

Research Papers

G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis

G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis

https://doi.org/10.18632/oncotarget.28433

Monalisa Parija, Amit K. Adhya,  and Sandip K. Mishra
466-480
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Corrections

Correction: Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

Correction: Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

https://doi.org/10.18632/oncotarget.28426

Astrid Escudero-Esparza, Michael Bartoschek, Chrysostomi Gialeli, Marcin Okroj, Sioned Owen, Karin Jirström, Akira Orimo, Wen G. Jiang, Kristian Pietras,  and Anna M. Blom
481-482
Correction  |  PDF  |  How to cite

Editorial

GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide

GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide

https://doi.org/10.18632/oncotarget.28370

Jun Ma, Ziyu Wang, Clark C. Chen,  and Ming Li
483-484
PDF  |  How to cite  |  Press Release

Research Papers

Role of creatine shuttle in colorectal cancer cells

Role of creatine shuttle in colorectal cancer cells

https://doi.org/10.18632/oncotarget.28436

Mayu Kita, Rina Fujiwara-Tani, Shingo Kishi, Shiori Mori, Hitoshi Ohmori, Chie Nakashima, Kei Goto, Takamitsu Sasaki, Kiyomu Fujii, Isao Kawahara, Ujjal Kumar Bhawal, Yi Luo,  and Hiroki Kuniyasu
485-501
Abstract  |  PDF  |  Full Text  |  How to cite

Addendum

Addendum: Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy

Addendum: Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy

https://doi.org/10.18632/oncotarget.28445

Stephanie A. Toll, Hung N. Tran, Jennifer Cotter, Alexander R. Judkins, Benita Tamrazi, Jaclyn A. Biegel, Girish Dhall, Nathan J. Robison, Kaaren Waters, Palak Patel, Robert Cooper,  and Ashley S. Margol
502-502
Addendum  |  PDF  |  How to cite

Research Perspectives

Targeting the Src N-terminal regulatory element in cancer

Targeting the Src N-terminal regulatory element in cancer

https://doi.org/10.18632/oncotarget.28434

Betlem Mezquita, Marjorie Reyes-Farias,  and Miquel Pons
503-513
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Latest updates on MET targeted therapy for EXON 14 mutations in lung cancer

Latest updates on MET targeted therapy for EXON 14 mutations in lung cancer

https://doi.org/10.18632/oncotarget.28419

Mira Al Jaberi, Wolfgang Clough,  and Samir Dalia
514-514
PDF  |  How to cite  |  Press Release

Addendum

Addendum: ROS1-GOPC/FIG: a novel gene fusion in hepatic angiosarcoma

Addendum: ROS1-GOPC/FIG: a novel gene fusion in hepatic angiosarcoma

https://doi.org/10.18632/oncotarget.28448

Eric I. Marks, Sahithi Pamarthy, Don Dizon, Ari Birnbaum, Evgeny Yakirevich, Howard Safran,  and Benedito A. Carneiro
515-515
Addendum  |  PDF  |  How to cite

Retraction

Retraction: Inhibition of microRNA-218 reduces HIF-1α by targeting on Robo1 in mice aortic endothelial cells under intermittent hypoxia

Retraction: Inhibition of microRNA-218 reduces HIF-1α by targeting on Robo1 in mice aortic endothelial cells under intermittent hypoxia

https://doi.org/10.18632/oncotarget.28449

Kai-Xiong Liu, Qin Chen, Gong-Ping Chen, Jian-Chai Huang, Jie-Feng Huang, Xin-Ru He, Ting Lin,  and Qi-Chang Lin
516-516
Retraction  |  PDF  |  How to cite

Research Papers

Value of chemotherapy post immunotherapy in stage IV non-small cell lung cancer (NSCLC)

Value of chemotherapy post immunotherapy in stage IV non-small cell lung cancer (NSCLC)

https://doi.org/10.18632/oncotarget.28444

Hazem I. Assi, Maroun Bou Zerdan, Mohammad Hodroj, Makram Khoury, Nour Sabiha Naji, Ghid Amhaz, Reine Abou Zeidane,  and Fadi El Karak
517-525
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Combined targeting of HEDGEHOG signaling and BRD4 as a novel therapeutic option against melanoma

Combined targeting of HEDGEHOG signaling and BRD4 as a novel therapeutic option against melanoma

https://doi.org/10.18632/oncotarget.28441

Silvia Pietrobono,  and Barbara Stecca
526-527
PDF  |  How to cite  |  Press Release

Research Papers

Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression

Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression

https://doi.org/10.18632/oncotarget.28442

Mohammad Salman Akhtar, Naseem Akhter, Arshi Talat, Raed A. Alharbi, Abdulmajeed A.A. Sindi, Faisal Klufah, Hanan E. Alyahyawi, Abdulmohsen Alruwetei, Abrar Ahmad, Mazin A. Zamzami, SVS Deo, Syed Akhtar Husain, Osama A. Badi,  and Mohammad Jahir Khan
528-541
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Addendum

Addendum: Laser speckle flowgraphy in juxtapapillary retinal capillary hemangioblastoma: a case report on natural course and therapeutic effect

Addendum: Laser speckle flowgraphy in juxtapapillary retinal capillary hemangioblastoma: a case report on natural course and therapeutic effect

https://doi.org/10.18632/oncotarget.28297

Mizuho Mitamura, Satoru Kase, Kiriko Hirooka,  and Susumu Ishida
542-542
Addendum  |  PDF  |  How to cite

Research Papers

Deconstructing the role of MALAT1 in MAPK-signaling in melanoma: insights from antisense oligonucleotide treatment

Deconstructing the role of MALAT1 in MAPK-signaling in melanoma: insights from antisense oligonucleotide treatment

https://doi.org/10.18632/oncotarget.28447

Valentin Feichtenschlager, Yixuan James Zheng, Wilson Ho, Linan Chen, Ciara Callanan, Christopher Chen, Albert Lee, Jose Ortiz, Klemens Rappersberger,  and Susana Ortiz-Urda
543-560
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

A macrophage is a macrophage is a macrophage—in metastasis

A macrophage is a macrophage is a macrophage—in metastasis

https://doi.org/10.18632/oncotarget.28423

Thomas T. Tapmeier
561-562
PDF  |  How to cite  |  Press Release

Reviews

ACSL4: biomarker, mediator and target in quadruple negative breast cancer

ACSL4: biomarker, mediator and target in quadruple negative breast cancer

https://doi.org/10.18632/oncotarget.28453

Marie E. Monaco
563-575
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

ERβ as a mediator of estrogen signaling in inflammatory breast cancer

ERβ as a mediator of estrogen signaling in inflammatory breast cancer

https://doi.org/10.18632/oncotarget.28425

Harika Nagandla,  and Christoforos Thomas
576-578
PDF  |  How to cite  |  Press Release

Retraction

Retraction: MicroRNA-363 inhibits ovarian cancer progression by inhibiting NOB1

Retraction: MicroRNA-363 inhibits ovarian cancer progression by inhibiting NOB1

https://doi.org/10.18632/oncotarget.28446

Yang Lin, Tianmin Xu, Shunqing Zhou,  and Manhua Cui
579-579
Retraction  |  PDF  |  How to cite

Research Papers

Investigating the prevalence of pathogenic variants in Saudi Arabian patients with familial cancer using a multigene next generation sequencing panel

Investigating the prevalence of pathogenic variants in Saudi Arabian patients with familial cancer using a multigene next generation sequencing panel

https://doi.org/10.18632/oncotarget.28457

Musa AlHarbi, Nahla Ali Mobark, Wael Abdel Rahman AlJabarat, Hadeel ElBardis, Ebtehal AlSolme, Abdullah Bany Hamdan, Ali H. AlFakeeh, Fatimah AlMushawah, Fawz AlHarthi, Abdullah A. AlSharm, Ali Abdullah O. Balbaid, Naji AlJohani, Alicia Y. Zhou, Heather A. Robinson, Saleh A. Alqahtani,  and Malak Abedalthagafi
580-594
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Editorial

Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?

Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?

https://doi.org/10.18632/oncotarget.28438

Chia-Chia Liu,  and Xiao-Song Wang
595-596
PDF  |  How to cite  |  Press Release

Research Papers

LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair

LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair

https://doi.org/10.18632/oncotarget.28454

Jianli Zhou, Drew Sturtevant, Cassie Love, Aditya Kulkarni, Neha Biyani, Umesh Kathad, Elizabeth Thacker, Sandeep Dave,  and Kishor Bhatia
597-611
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

The hope for targeting fatty acid binding proteins in multiple myeloma

The hope for targeting fatty acid binding proteins in multiple myeloma

https://doi.org/10.18632/oncotarget.28437

Heather Fairfield,  and Michaela R. Reagan
612-613
PDF  |  How to cite

Research Perspectives

Targeting GITR in cancer immunotherapy – there is no perfect knowledge

Targeting GITR in cancer immunotherapy – there is no perfect knowledge

https://doi.org/10.18632/oncotarget.28461

Diwakar Davar,  and Roberta Zappasodi
614-621
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer

Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer

https://doi.org/10.18632/oncotarget.28458

Devalingam Mahalingam, Salih Hanni, Anthony V. Serritella, Christos Fountzilas, Joel Michalek, Brian Hernandez, John Sarantopoulos, Paromitta Datta, Ofelia Romero, Sureshkumar Mulampurath Achutan Pillai, John Kuhn, Michael Pollak,  and Ian M. Thompson
622-636
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells

Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells

https://doi.org/10.18632/oncotarget.28465

André Luiz Mendes Juchem, Cristiano Trindade, Juliana Bondan da Silva, Miriana da Silva Machado, Temenouga Nikolova Guecheva, Jaqueline Cesar Rocha, Jenifer Saffi, Iuri Marques de Oliveira, João Antonio Pêgas Henriques,  and Alexandre Escargueil
637-649
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Corrections

Correction: iASPP overexpression is associated with clinical outcome in spinal chordoma and influences cellular proliferation, invasion, and sensitivity to cisplatin in vitro

Correction: iASPP overexpression is associated with clinical outcome in spinal chordoma and influences cellular proliferation, invasion, and sensitivity to cisplatin in vitro

https://doi.org/10.18632/oncotarget.28395

Yunlong Ma, Bin Zhu, Xiaoguang Liu, Zhongjun Liu, Liang Jiang, Feng Wei, Miao Yu, Fengliang Wu, Hua Zhou, Nanfang Xu, Xiao Liu, Lei Yong, Yongqiang Wang, Peng Wang, Chen Liang,  and Guanping He
650-652
Correction  |  PDF  |  How to cite

Editorial

Decoding the mechanism behind MCL-1 inhibitors: A pathway to understanding MCL-1 protein stability

Decoding the mechanism behind MCL-1 inhibitors: A pathway to understanding MCL-1 protein stability

https://doi.org/10.18632/oncotarget.28440

Shady I. Tantawy, Natalia Timofeeva, Ana Hernandez, Aloke Sarkar,  and Varsha Gandhi
653-655
PDF  |  How to cite  |  Press Release

Addendum

Addendum: Cerebral hemorrhage due to tuberculosis meningitis: a rare case report and literature review

Addendum: Cerebral hemorrhage due to tuberculosis meningitis: a rare case report and literature review

https://doi.org/10.18632/oncotarget.28284

Hai Zou, Ke-Hua Pan, Hong-Ying Pan, Dong-Sheng Huang,  and Ming-Hua Zheng
656-656
Addendum  |  PDF  |  How to cite

Editorial

The dark side of PLK1: Implications for cancer and genomic instability

The dark side of PLK1: Implications for cancer and genomic instability

https://doi.org/10.18632/oncotarget.28456

Lilia Gheghiani,  and Zheng Fu
657-659
PDF  |  How to cite

Research Perspectives

Deciphering the mechanisms of action of progesterone in breast cancer

Deciphering the mechanisms of action of progesterone in breast cancer

https://doi.org/10.18632/oncotarget.28455

Gaurav Chakravorty, Suhail Ahmad, Mukul S. Godbole, Sudeep Gupta, Rajendra A. Badwe,  and Amit Dutt
660-667
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Addendum

Addendum: Immune-related adverse events and atypical radiological response with checkpoint inhibitor immunotherapy in an elderly patient with high PD-L1 expressing lung adenocarcinoma

Addendum: Immune-related adverse events and atypical radiological response with checkpoint inhibitor immunotherapy in an elderly patient with high PD-L1 expressing lung adenocarcinoma

https://doi.org/10.18632/oncotarget.28471

Eduard Teixidor, Elia Sais, Carmen Amalia Vásquez, Walter Carbajal, Alejandro Hernández, Gloria Sánchez, Angel Izquierdo, Sara Verdura, Javier A. Menéndez,  and Joaquim Bosch-Barrera
668-668
Addendum  |  PDF  |  How to cite

Retraction

Retraction: Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer

Retraction: Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer

https://doi.org/10.18632/oncotarget.28439

Erhong Meng, Lalita A. Shevde,  and Rajeev S. Samant
669-669
Retraction  |  PDF  |  How to cite

Editorial

Obesity paradox and lung cancer, metformin-based therapeutic opportunity?

Obesity paradox and lung cancer, metformin-based therapeutic opportunity?

https://doi.org/10.18632/oncotarget.28432

Pedro Barrios-Bernal, Norma Hernández-Pedro, Luis Lara-Mejía,  and Oscar Arrieta
670-671
PDF  |  How to cite  |  Press Release

Reviews

Targeting Ras with protein engineering

Targeting Ras with protein engineering

https://doi.org/10.18632/oncotarget.28469

Atilio Tomazini,  and Julia M. Shifman
672-687
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

Transformation of immunosuppressive mtKRAS tumors into immunostimulatory tumors by Nerofe and Doxorubicin

Transformation of immunosuppressive mtKRAS tumors into immunostimulatory tumors by Nerofe and Doxorubicin

https://doi.org/10.18632/oncotarget.28467

Joel Ohana, Uziel Sandler, Orly Devary,  and Yoram Devary
688-699
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Corrections

Correction: Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis

Correction: Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis

https://doi.org/10.18632/oncotarget.28472

Letícia F. Leal, Ana Carolina Bueno, Débora C. Gomes, Rafael Abduch, Margaret de Castro,  and Sonir R. Antonini
700-700
Correction  |  PDF  |  How to cite

Editorial

Systemic treatment for brain metastasis in HER2- positive advanced breast cancer: what have we learned so far?

Systemic treatment for brain metastasis in HER2- positive advanced breast cancer: what have we learned so far?

https://doi.org/10.18632/oncotarget.28435

Marta Vaz Batista, José Perez-Gracia, Inês Eiriz, Maria Gion, Antonio Llombart, Sofia Braga,  and Javier Cortés
701-702
PDF  |  How to cite  |  Press Release

Case Reports

Intrathoracic synovial sarcoma with BRAF V600E mutation

Intrathoracic synovial sarcoma with BRAF V600E mutation

https://doi.org/10.18632/oncotarget.28475

Ida Russo, Sabina Barresi, Pier Luigi Di Paolo, Valentina Di Ruscio, Giada Del Baldo, Annalisa Serra, Silvia Vallese, Evelina Miele, Angela Mastronuzzi, Rita Alaggio, Andrea Ferrari,  and Giuseppe Maria Milano
703-708
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

Effectiveness and toxicity of cetuximab with concurrent RT in locally advanced cutaneous squamous cell skin cancer: a case series

Effectiveness and toxicity of cetuximab with concurrent RT in locally advanced cutaneous squamous cell skin cancer: a case series

https://doi.org/10.18632/oncotarget.28470

Mark Chang, Wolfram Samlowski,  and Raul Meoz
709-718
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Multiclonality of ER expression in DCIS – Implications for clinical practice and future research

Multiclonality of ER expression in DCIS – Implications for clinical practice and future research

https://doi.org/10.18632/oncotarget.28450

Mangesh A. Thorat
719-720
PDF  |  How to cite  |  Press Release  |  Video Interview

Addendum

Addendum: Systemic AL amyloidosis: current approach and future direction

Addendum: Systemic AL amyloidosis: current approach and future direction

https://doi.org/10.18632/oncotarget.28478

Maroun Bou Zerdan, Lewis Nasr, Farhan Khalid, Sabine Allam, Youssef Bouferraa, Saba Batool, Muhammad Tayyeb, Shubham Adroja, Mahinbanu Mammadii, Faiz Anwer, Shahzad Raza,  and Chakra P. Chaulagain
721-721
Addendum  |  PDF  |  How to cite

Addendum

Addendum: LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin’s lymphoma models and in cells deficient in DNA damage repair

Addendum: LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin’s lymphoma models and in cells deficient in DNA damage repair

https://doi.org/10.18632/oncotarget.28479

Jianli Zhou, Drew Sturtevant, Cassie Love, Aditya Kulkarni, Neha Biyani, Umesh Kathad, Elizabeth Thacker, Sandeep Dave,  and Kishor Bhatia
722-722
Addendum  |  PDF  |  How to cite

Research Papers

The uncharacterized transcript KIAA0930 confers a cachexic phenotype on cancer cells

The uncharacterized transcript KIAA0930 confers a cachexic phenotype on cancer cells

https://doi.org/10.18632/oncotarget.28476

Takahiro Yamakawa, Guoxiang Zhang, Liza Bengrine Najjar, Chun Li,  and Keiichi Itakura
723-737
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers

Development of a multiplex assay to assess activated p300/CBP in circulating prostate tumor cells

Development of a multiplex assay to assess activated p300/CBP in circulating prostate tumor cells

https://doi.org/10.18632/oncotarget.28477

Mikolaj Filon, Bing Yang, Tanaya A. Purohit, Jennifer Schehr, Anupama Singh, Marcelo Bigarella, Peter Lewis, John Denu, Joshua Lang,  and David F. Jarrard
738-746
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Addendum

Addendum: Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss

Addendum: Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss

https://doi.org/10.18632/oncotarget.28481

Maroun Bou Zerdan, Prashanth Ashok Kumar, Elio Haroun, Nimisha Srivastava, Jeffrey Ross,  and Abirami Sivapiragasam
747-747
Addendum  |  PDF  |  How to cite

Addendum

Addendum: What is hemoglobin, albumin, lymphocyte, platelet (HALP) score? A comprehensive literature review of HALP’s prognostic ability in different cancer types

Addendum: What is hemoglobin, albumin, lymphocyte, platelet (HALP) score? A comprehensive literature review of HALP’s prognostic ability in different cancer types

https://doi.org/10.18632/oncotarget.28485

Christian Mark Farag, Ryan Antar, Sinan Akosman, Matthew Ng,  and Michael J. Whalen
748-748
Addendum  |  PDF  |  How to cite

Research Perspectives

CDK9 INHIBITORS: a promising combination partner in the treatment of hematological malignancies

CDK9 INHIBITORS: a promising combination partner in the treatment of hematological malignancies

https://doi.org/10.18632/oncotarget.28473

Daniel Morillo, Gala Vega,  and Victor Moreno
749-752
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Addendum

Addendum: Effectiveness and toxicity of cetuximab with concurrent RT in locally advanced cutaneous squamous cell skin cancer: a case series

Addendum: Effectiveness and toxicity of cetuximab with concurrent RT in locally advanced cutaneous squamous cell skin cancer: a case series

https://doi.org/10.18632/oncotarget.28480

Mark Chang, Wolfram Samlowski,  and Raul Meoz
753-753
Addendum  |  PDF  |  How to cite

Addendum

Addendum: ACSL4: biomarker, mediator and target in quadruple negative breast cancer

Addendum: ACSL4: biomarker, mediator and target in quadruple negative breast cancer

https://doi.org/10.18632/oncotarget.28482

Marie E. Monaco
754-754
Addendum  |  PDF  |  How to cite

Editorial

Inhibition of glutamine metabolism: acting on tumoral cells or on tumor microenvironment?

Inhibition of glutamine metabolism: acting on tumoral cells or on tumor microenvironment?

https://doi.org/10.18632/oncotarget.28443

Raul Peña
755-757
PDF  |  How to cite  |  Press Release

Reviews

Peripheral surrogates of tumor burden to guide chemotherapeutic and immunotherapeutic strategies for HPV-associated malignancies

Peripheral surrogates of tumor burden to guide chemotherapeutic and immunotherapeutic strategies for HPV-associated malignancies

https://doi.org/10.18632/oncotarget.28487

Meghali Goswami, Jeffrey Schlom,  and Renee N. Donahue
758-774
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Predicting the molecular functions of regulatory genetic variants associated with cancer

Predicting the molecular functions of regulatory genetic variants associated with cancer

https://doi.org/10.18632/oncotarget.28451

Jun S. Song,  and Mohith Manjunath
775-777
PDF  |  How to cite  |  Press Release

Addendum

Addendum: Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis

Addendum: Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis

https://doi.org/10.18632/oncotarget.28484

Michael Jonathan Kucharczyk, Andrew Bang, Michael C. Tjong, Stefania Papatheodorou,  and Jesus C. Fabregas
778-778
Addendum  |  PDF  |  How to cite

Retraction

Retraction: The prognostic potential and carcinogenesis of long non-coding RNA TUG1 in human cholangiocarcinoma

Retraction: The prognostic potential and carcinogenesis of long non-coding RNA TUG1 in human cholangiocarcinoma

https://doi.org/10.18632/oncotarget.28418

Yi Xu, Kaiming Leng, Zhenglong Li, Fumin Zhang, Xiangyu Zhong, Pengcheng Kang, Xingming Jiang,  and Yunfu Cui
779-779
Retraction  |  PDF  |  How to cite

Editorial

Subpopulations of AIB1 isoform-expressing breast cancer cells enable invasion and metastasis

Subpopulations of AIB1 isoform-expressing breast cancer cells enable invasion and metastasis

https://doi.org/10.18632/oncotarget.28452

Amber J. Kiliti, Ghada M. Sharif, Anton Wellstein,  and Anna T. Riegel
780-781
PDF  |  How to cite  |  Press Release

Corrections

Correction: Interferon beta induces apoptosis in nasopharyngeal carcinoma cells via the TRAIL-signaling pathway

Correction: Interferon beta induces apoptosis in nasopharyngeal carcinoma cells via the TRAIL-signaling pathway

https://doi.org/10.18632/oncotarget.28464

Anna Makowska, Lora Wahab, Till Braunschweig, Nikiforos-Ioannis Kapetanakis, Christian Vokuhl, Bernd Denecke, Lian Shen, Pierre Busson,  and Udo Kontny
782-787
Correction  |  PDF  |  How to cite

Addendum

Addendum: Sequencing of BRCA1/2-alterations using NGS-based technology: annotation as a challenge

Addendum: Sequencing of BRCA1/2-alterations using NGS-based technology: annotation as a challenge

https://doi.org/10.18632/oncotarget.28483

Silvana Ebner, Ria Winkelmann, Saskia Martin, Jens Köllermann, Peter J. Wild,  and Melanie Demes
788-788
Addendum  |  PDF  |  How to cite

Research Papers

Analytic validation of NeXT Dx™, a comprehensive genomic profiling assay

Analytic validation of NeXT Dx™, a comprehensive genomic profiling assay

https://doi.org/10.18632/oncotarget.28490

Juan-Sebastian Saldivar, Jason Harris, Erin Ayash, Manqing Hong, Prateek Tandon, Saloni Sinha, Patricia Miranda Hebron, Erin E. Houghton, Kaleigh Thorne, Laurie J. Goodman, Conan Li, Twinkal R. Marfatia, Joshua Anderson, Massimo Morra, John Lyle, Gabor Bartha,  and Richard Chen
789-806
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Potential repurposing of DPP4 inhibitors for target therapy resistance in renal cell carcinoma

Potential repurposing of DPP4 inhibitors for target therapy resistance in renal cell carcinoma

https://doi.org/10.18632/oncotarget.28463

Kuniko Horie,  and Satoshi Inoue
807-808
PDF  |  How to cite  |  Press Release

Corrections

Correction: MiR-129 blocks estrogen induction of NOTCH signaling activity in breast cancer stem-like cells

Correction: MiR-129 blocks estrogen induction of NOTCH signaling activity in breast cancer stem-like cells

https://doi.org/10.18632/oncotarget.28201

Guodong Xiao, Xiang Li, Gang Li, Boxiang Zhang, Chongwen Xu, Sida Qin, Ning Du, Jichang Wang, Shou-Ching Tang, Jing Zhang, Hong Ren, Ke Chen,  and Xin Sun
809-809
Correction  |  PDF  |  How to cite

Addendum

Addendum: Crosstalk between triple negative breast cancer and microenvironment

Addendum: Crosstalk between triple negative breast cancer and microenvironment

https://doi.org/10.18632/oncotarget.28507

Karly Smrekar, Artem Belyakov,  and Kideok Jin
810-810
Addendum  |  PDF  |  How to cite

Research Papers

Real time ex vivo chemosensitivity assay for pancreatic adenocarcinoma

Real time ex vivo chemosensitivity assay for pancreatic adenocarcinoma

https://doi.org/10.18632/oncotarget.28508

Dae Won Kim, Francisca Beato, Youngchul Kim, Alexandra F. Tassielli, Ruifan Dai, Jason W. Denbo, Pamela J. Hodul, Mokenge P. Malafa,  and Jason B. Fleming
811-818
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

Reassessing the risks and benefits of COVID-19 precautions in 2023

Reassessing the risks and benefits of COVID-19 precautions in 2023

https://doi.org/10.18632/oncotarget.28468

Thomas A. Ollila, Rashida Taher,  and Prashanth Moku
819-820
PDF  |  How to cite  |  Press Release

Corrections

Correction: Adipocytes secreted leptin is a pro-tumor factor for survival of multiple myeloma under chemotherapy

Correction: Adipocytes secreted leptin is a pro-tumor factor for survival of multiple myeloma under chemotherapy

https://doi.org/10.18632/oncotarget.28236

Wen Yu, De-Dong Cao, Qiu-bai Li, Hui-ling Mei, Yu Hu,  and Tao Guo
821-823
Correction  |  PDF  |  How to cite

Addendum

Addendum: The chromatographic constitution of andiroba oil and its healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option

Addendum: The chromatographic constitution of andiroba oil and its healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option

https://doi.org/10.18632/oncotarget.28504

Jessica T. Gomes, Ana Márcia V. Wanzeler, Sergio M.A. Júnior, Rosa Helena F. Chaves Soares, Carolina P. de Oliveira, Emanuelle de M. Rodrigues, Bruno M. Soares, Diego D.F.A. Alcantara, Rommel M.R. Burbano,  and Fabrício M. Tuji
824-824
Addendum  |  PDF  |  How to cite

Research Papers

Transcriptomic analysis identifies four novel receptors potentially linking endometrial cancer with polycystic ovary syndrome and generates a transcriptomic atlas

Transcriptomic analysis identifies four novel receptors potentially linking endometrial cancer with polycystic ovary syndrome and generates a transcriptomic atlas

https://doi.org/10.18632/oncotarget.28513

Fatma Alqutami, Mahmood Hachim, Charlie Hodgman,  and William Atiomo
825-835
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Addendum

Addendum: Impact of Covid-19 on the management of patients with metastatic melanoma

Addendum: Impact of Covid-19 on the management of patients with metastatic melanoma

https://doi.org/10.18632/oncotarget.28496

Michèle Welti, Phil F. Cheng, Joanna Mangana, Mitchell P. Levesque, Reinhard Dummer,  and Laurence Imhof
836-836
Addendum  |  PDF  |  How to cite

Corrections

Correction: HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomide

Correction: HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomide

https://doi.org/10.18632/oncotarget.28515

Alessandro Canella, Hector Cordero Nieves, Douglas W. Sborov, Luciano Cascione, Hanna S. Radomska, Emily Smith, Andrew Stiff, Jessica Consiglio, Enrico Caserta, Lara Rizzotto, Nicola Zanesi, Volinia Stefano, Balveen Kaur, Xiaokui Mo, John C. Byrd, Yvonne A. Efebera, Craig C. Hofmeister,  and Flavia Pichiorri
837-838
Correction  |  PDF  |  How to cite

Editorial

DISE, an ancient anti-cancer mechanism that senses mutational load in cancerous cells?

DISE, an ancient anti-cancer mechanism that senses mutational load in cancerous cells?

https://doi.org/10.18632/oncotarget.28466

Monal Patel,  and Marcus E. Peter
839-841
PDF  |  How to cite  |  Press Release

Corrections

Correction: Induction of phenotypic changes in HER2-postive breast cancer cells in vivo and in vitro

Correction: Induction of phenotypic changes in HER2-postive breast cancer cells in vivo and in vitro

https://doi.org/10.18632/oncotarget.28520

Anastasia Frank-Kamenetskii, Julia Mook, Meredith Reeves, Corinne A. Boulanger, Thomas J. Meyer, Lauren Ragle, H. Caroline Jordan, Gilbert H. Smith,  and Brian W. Booth
842-842
Correction  |  PDF  |  How to cite

Reviews

UDP-glucose dehydrogenase (UGDH) in clinical oncology and cancer biology

UDP-glucose dehydrogenase (UGDH) in clinical oncology and cancer biology

https://doi.org/10.18632/oncotarget.28514

Meghan J. Price, Annee D. Nguyen, Jovita K. Byemerwa, Jasmine Flowers, César D. Baëta,  and C. Rory Goodwin
843-857
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial Perspective

STAT3 as a biologically relevant target in H3K27M-mutant diffuse midline glioma

STAT3 as a biologically relevant target in H3K27M-mutant diffuse midline glioma

https://doi.org/10.18632/oncotarget.28516

Jacob B. Anderson, Samantha M. Bouchal, Liang Zhang,  and David J. Daniels
858-859
PDF  |  How to cite  |  Press Release

Research Papers

Determination of genetic predisposition to early breast cancer in women of Kazakh ethnicity

Determination of genetic predisposition to early breast cancer in women of Kazakh ethnicity

https://doi.org/10.18632/oncotarget.28518

Gulnur Zhunussova, Nazgul Omarbayeva, Dilyara Kaidarova, Saltanat Abdikerim, Natalya Mit, Ilya Kisselev, Kanagat Yergali, Aigul Zhunussova, Tatyana Goncharova, Aliya Abdrakhmanova,  and Leyla Djansugurova
860-877
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: Serum amyloid a induces M2b-like macrophage polarization during liver inflammation

Retraction: Serum amyloid a induces M2b-like macrophage polarization during liver inflammation

https://doi.org/10.18632/oncotarget.28498

Yibin Wang, Haijun Huang, Renhua Sun, Bingyu Chen, Fang Han, Qian Li, Yin Ni, Xi Li, Jingquan Liu, Xiaozhou Mou,  and Yuexing Tu
878-878
Retraction  |  PDF  |  How to cite

Research Papers

Inhibiting BRAF/EGFR/MEK suppresses cancer stemness and drug resistance of primary colorectal cancer cells

Inhibiting BRAF/EGFR/MEK suppresses cancer stemness and drug resistance of primary colorectal cancer cells

https://doi.org/10.18632/oncotarget.28517

Astha Lamichhane, Gary D. Luker, Seema Agarwal,  and Hossein Tavana
879-889
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Corrections

Correction: Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer

Correction: Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer

https://doi.org/10.18632/oncotarget.28530

Devalingam Mahalingam, Salih Hanni, Anthony V. Serritella, Christos Fountzilas, Joel Michalek, Brian Hernandez, John Sarantopoulos, Paromitta Datta, Ofelia Romero, Sureshkumar Mulampurath Achutan Pillai, John Kuhn, Michael Pollak,  and Ian M. Thompson
890-892
Correction  |  PDF  |  How to cite

Research Papers

Apoptotic cells may drive cell death in hair follicles during their regression cycle

Apoptotic cells may drive cell death in hair follicles during their regression cycle

https://doi.org/10.18632/oncotarget.28529

Bradley D. Keister, Kailin R. Mesa,  and Krastan B. Blagoev
893-899
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

GLS2 shapes ferroptosis in hepatocellular carcinoma

GLS2 shapes ferroptosis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.28526

Sawako Suzuki, Divya Venkatesh, Tomoaki Tanaka,  and Carol Prives
900-903
PDF  |  How to cite  |  Press Release

Editorial

The uncharted role of HER2 mutant alleles in breast cancer

The uncharted role of HER2 mutant alleles in breast cancer

https://doi.org/10.18632/oncotarget.28489

Rashi Kalra, Bora Lim, Matthew J. Ellis,  and Shyam M. Kavuri
904-907
PDF  |  How to cite  |  Press Release

Corrections

Correction: MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase

Correction: MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase

https://doi.org/10.18632/oncotarget.28533

Recep Bayraktar, Martin Pichler, Pinar Kanlikilicer, Cristina Ivan, Emine Bayraktar, Nermin Kahraman, Burcu Aslan, Serpil Oguztuzun, Mustafa Ulasli, Ahmet Arslan, George Calin, Gabriel Lopez-Berestein,  and Bulent Ozpolat
908-909
Correction  |  PDF  |  How to cite

Research Papers

FAAH inhibition ameliorates breast cancer in a murine model

FAAH inhibition ameliorates breast cancer in a murine model

https://doi.org/10.18632/oncotarget.28534

Mallika Tripathy, Amy Bui, Jared Henderson, Jeffrey Sun, Christian Rutan Woods, Soumya Somani, Thao Doan, Anto Sam Crosslee Louis Sam Titus,  and Chandra Mohan
910-918
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Editorial

The double-edge sword of CRISPR application for in vivo studies

The double-edge sword of CRISPR application for in vivo studies

https://doi.org/10.18632/oncotarget.28459

Martin K. Thomsen
919-920
PDF  |  How to cite  |  Press Release

Reviews

Risk factors for long-term arm morbidities following breast cancer treatments: A systematic review

Risk factors for long-term arm morbidities following breast cancer treatments: A systematic review

https://doi.org/10.18632/oncotarget.28539

Ifat Klein, Michael Friger, Merav Ben David,  and Danit Shahar
921-942
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Retraction

Retraction: Matrine alleviates lipopolysaccharide-induced intestinal inflammation and oxidative stress via CCR7 signal

Retraction: Matrine alleviates lipopolysaccharide-induced intestinal inflammation and oxidative stress via CCR7 signal

https://doi.org/10.18632/oncotarget.28119

Guojun Wu, Wenhong Zhou, Junfeng Zhao, Xiaohua Pan, Yongjie Sun, Hao Xu, Peng Shi, Chong Geng, Ling Gao,  and Xingsong Tian
943-943
Retraction  |  PDF  |  How to cite

Editorial

Therapeutic potentials and challenges of cytostatic persister cancer cells

Therapeutic potentials and challenges of cytostatic persister cancer cells

https://doi.org/10.18632/oncotarget.28488

Paul Y. Kim,  and Cheuk T. Leung
944-945
PDF  |  How to cite  |  Press Release

Addendum

Addendum: Nasal NK/T cell lymphoma presents with long-term nasal blockage and fever: a rare case report and literature review

Addendum: Nasal NK/T cell lymphoma presents with long-term nasal blockage and fever: a rare case report and literature review

https://doi.org/10.18632/oncotarget.28285

Hai Zou, Ke-Hua Pan, Liang Wu, Hong-Ying Pan, Ya-Hui Ding,  and Ming-Hua Zheng
946-946
Addendum  |  PDF  |  How to cite

Editorial

Reductive carboxylation of glutamine as a potential target in acute myeloid leukemia

Reductive carboxylation of glutamine as a potential target in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.28474

Alessia Roma, Lawrence D. Goodridge,  and Paul A. Spagnuolo
947-948
PDF  |  How to cite  |  Press Release

Research Papers

Plasma levels of BCMA-positive extracellular vesicles correlate to response and side effects in myeloma patients treated with belantamab-mafodotin

Plasma levels of BCMA-positive extracellular vesicles correlate to response and side effects in myeloma patients treated with belantamab-mafodotin

https://doi.org/10.18632/oncotarget.28538

Carsten Springer, Jürgen Krauter,  and Arne Trummer
949-956
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Research Papers

Osteopontin induces mitochondrial biogenesis in deadherent cancer cells

Osteopontin induces mitochondrial biogenesis in deadherent cancer cells

https://doi.org/10.18632/oncotarget.28540

Gulimirerouzi Fnu,  and Georg F. Weber
957-969
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Video Interview

Corrections

Correction: Abnormal topological organization in white matter structural networks in survivors of acute lymphoblastic leukaemia with chemotherapy treatment

Correction: Abnormal topological organization in white matter structural networks in survivors of acute lymphoblastic leukaemia with chemotherapy treatment

https://doi.org/10.18632/oncotarget.28535

Liwei Zou, Lianzi Su, Rongmiao Qi, Fang Bao, Xianjing Fang, Longsheng Wang, Zhimin Zhai, Dan Li,  and Suisheng Zheng
970-970
Correction  |  PDF  |  How to cite

Addendum

Addendum: Importance of carbohydrate antigen (CA 19-9) and carcinoembrionic antigen (CEA) in the prognosis of patients with duodenal adenocarcinoma: a retrospective single-institution cohort study

Addendum: Importance of carbohydrate antigen (CA 19-9) and carcinoembrionic antigen (CEA) in the prognosis of patients with duodenal adenocarcinoma: a retrospective single-institution cohort study

https://doi.org/10.18632/oncotarget.28491

Ellery Altshuler, Raymond Richhart, William King, Mahmoud Aryan, Akash Mathavan, Akshay Mathavan, Keegan Hones, Daniel F. Leach III, Logan Pucci, Joshua Riklan, Pat Haley, Ilyas Sahin, Brian Ramnaraign, Sherise Rogers, Ibrahim Nassour, Steven Hughes, Thomas J. George,  and Jesus Fabregas
971-971
Addendum  |  PDF  |  How to cite

Research Perspectives

Melatonin and carcinogenesis in mice: the 50th anniversary of relationships

Melatonin and carcinogenesis in mice: the 50th anniversary of relationships

https://doi.org/10.18632/oncotarget.28537

Vladimir N. Anisimov,  and Alexey G. Golubev
972-976
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Reviews

Current perspectives on the management of refractory or relapsed classic hodgkin lymphoma in Brazil: Balancing efficacy, safety, and tolerability

Current perspectives on the management of refractory or relapsed classic hodgkin lymphoma in Brazil: Balancing efficacy, safety, and tolerability

https://doi.org/10.18632/oncotarget.28541

Flávia Dias Xavier, Danielle Leão Cordeiro de Farias, Abrahão Elias Hallack Neto, Glaciano Nogueira Ribeiro, Marco Aurelio Salvino de Araujo, Thiago Xavier Carneiro,  and Otavio Cesar Carvalho Guimarães Baiocchi
977-994
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

Therapeutically harnessing cancer stem cell-derived exosomes

Therapeutically harnessing cancer stem cell-derived exosomes

https://doi.org/10.18632/oncotarget.28542

Yong Teng
995-996
PDF  |  How to cite  |  Press Release

Research Papers

The pharmacodynamic and mechanistic foundation for the antineoplastic effects of GFH009, a potent and highly selective CDK9 inhibitor for the treatment of hematologic malignancies

The pharmacodynamic and mechanistic foundation for the antineoplastic effects of GFH009, a potent and highly selective CDK9 inhibitor for the treatment of hematologic malignancies

https://doi.org/10.18632/oncotarget.28543

Fusheng Zhou, Lili Tang, Siyuan Le, Mei Ge, Dragan Cicic, Fubo Xie, Jinmin Ren, Jiong Lan,  and Qiang Lu
997-1008
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Reviews

Transformation-associated recombination (TAR) cloning and its applications for gene function; genome architecture and evolution; biotechnology and biomedicine

Transformation-associated recombination (TAR) cloning and its applications for gene function; genome architecture and evolution; biotechnology and biomedicine

https://doi.org/10.18632/oncotarget.28546

Natalay Kouprina,  and Vladimir Larionov
1009-1033
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Editorial

One more step toward treatment of PARP inhibitor-resistant ovarian cancers

One more step toward treatment of PARP inhibitor-resistant ovarian cancers

https://doi.org/10.18632/oncotarget.28545

Upasana Ray, Prabhu Thirusangu,  and Viji Shridhar
1034-1035
PDF  |  How to cite  |  Press Release


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